17 terms

microbiology: mutation, repairs and recombination

point mutation
mutation that's the addition, deletion or substitution of a single base
mutation that's any change in the genetic code that leads to placement of a different amino acid during translation (a codon is changed)
silent mutation
mutation that alters a base but does not change the amino acid (because it gets another codon for the same acid)
when a mutated gene goes back to its original state
chemical carcinogens
the Ames test is one based on back-mutations and tests for _____ _______
frameshift mutation, complete change of proteins
mutation that that happens because a reading frame of mRNA has been changed by insertion or deletion of bases. does this change the protein being made?
excision repair
mutation repair where special enzymes remove incorrect bases and add correct ones. only seen in some bacteria.
light repair
mutation repair when enzymes produced in the presence of light repair the DNA
ames test, mutation
the _____ test expresses back mutation. a bacterial gene is marked and used to test the _______ rate of a chemical.
higher, potent
in the ames test, the _____ the rate of back mutation, the more ______ the mutagen (carcinogen in humans)
the genetic transfer of dna from one bacterium to another
the _______ organism is the one in recombination that has and expresses the NEW dna
type of recombination that involves the direct exchange of plasmids
type of recombination where naked dna transfers indirectly
the _______test proved that dna from a dead cell can be acquired and expressed by a live cell
what is the virulence factor in a griffith's test?
type of recombination in which a bacteriophage (virus) is the vector using donor & recipient cells