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Roles include: component of cell membranes, precursor of bile acids, precursor of steroids
On sinusoidal surface of liver cells, hydrolyzes TG into FFAs and glycerol; does not react readily with chylomicrons, handles TG hydrolysis of chylomicron remnants and HDL metabolism
Familial combined hypercholesterolemia
Increased LDL and VLDL due to overproduction of VDL -> Increased LDL
In adipose tissue and muscle, insulin stimulates insertion of a ____ into the cell membrane
androgen binding protein
Sertoli cells in the testes produce ____, which helps to concentrate testosterone to high levels in the testes
ovulate in response to hormonal changes at the end of the follicular phase of the estrous or menstrual cycle
have the genes and sex organs of one sex but the appearance of the opposite sex
XXY gene, seminiferous tubules do not develop, resulting in infertility; elevated E/T ratio
both ovarian and testicular tissue are present. Individuals may appear male or female depending on whether testosterone was produced in quantities sufficient to stimulate development of male genitalia
___ stimulate the excitability of uterine muscle and progesterone inhibits uterine contractions
placental production of estrogen, progesterone, hCG, and hPL may contribute to maternal ____
vasopressin and angiotensin
During pre-eclampsia, the mother has abnormally increased sensitivity to _____
Breast cancer is a malignant proliferation of ___ cells lining the ducts or lobules of the breast
member of the epidermal growth factor receptor superfamily that is overexpressed in most breast cancers
One early change during the development of prostrate cancer is the hypermethylation of the ___ gene promoter
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