Drug Classification: Penicillins
Therapeutic Use: same as penicillin G
Contraindication: The molecular weight, degree of protein binding, and pharmacokinetic profile of clavulanic acid together with information from a single patient with renal insufficiency all suggest that this compound may also be removed by hemodialysis or hypersensitivity.
Therapeutic Blood serum level:330 mcg/mL
Adverse effects: same as penicillin G
Usual Dose: up to 3.1 g IV q4-6h or 200-300 mg/kg/d IV in divided doses q4-6h
Nursing Implications: As with any penicillin, an allergic reaction, including anaphylaxis, may occur during administration of TIMENTIN, particularly in a hypersensitive individual.
Patient/ family teaching: The nurse should advise the patient if they have diarrhea that is watery or bloody;blood in your urine, feeling an urgent need to urinate, painful or difficult urination;
easy bruising or bleeding, unusual weakness;dry mouth, increased thirst, confusion, increased urination, muscle pain or weakness, fast heart rate, feeling light-headed, fainting;fever, chills, body aches, flu symptoms;fever, sore throat, and headache with a severe blistering, peeling, and red skin rash;chest pain; or seizure (convulsions) to contact the primary care provider immediately.