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Innate and Adaptive Jeopardy Questions
Terms in this set (25)
Phagocytic cell type that resides in tissues and develops from monocytes.
Another term for transmigration of neutrophils through vascular endothelium.
Adhesion molecules that facilitate neutrophil rolling along vascular endothelium.
Signal delivered by T cells that is required for B cell isotope switching and requires cell-to-cell contact.
In addition to antigen and costimulation, this signal is required for the differentiation of naive CD4 T cells into Th1 effectors.
Type of cytokine that directs cells towards the site of infection.
Cytokine that activates macrophage bactericidal function.
Cytokine produced by T cells that recruits neutrophils to infected mucosal surfaces.
Cytokine required for NK cell development.
Receptor required for the detection of IL-2, IL-7, IL-15
common gamma chain cytokine receptor (IL2RG)
Predominant antibody isotype in people with CD40-deficiency.
Enzyme required for somatic hypermutation.
Activation-induced cytidine deaminase (AID)
Two ways that the complement system destroys bacteria.
Opsonization and formation of the membrane attack complex.
Antibody isotope that neutralizes pathogens, but has weak opsonization and complement fixing activities.
Frequency of IVIG administration in patients with SCID.
Molecule involved in tissue transplant rejection. Later, Rolf Zinkernagel and Peter Doherty discovered that it also presents viral antigens to cytotoxic T cells.
Major Histocompatibility Complex I (MHC I)
Myeloid-derived antigen presenting cells discovered by Ralph Steinman.
Process discovered by Susumu Tonegawa that is responsible for generating antibody diversity.
Innate humoral group of proteins discovered by Jules Bordet that helps the immune system to recognize and destroy bacteria.
1) The receptor for lipopolysaccharide (LPS), and
2) Cytokine produced in response to LPS. These findings were discovered by Bruce Beutler. Hint: the cytokine is named for its anti-cancer activity.
1) Toll-like receptor 4 (TLR4)
2) Tumor Necrosis Factor (TNF)
Term for a lymphocyte that persists following an infection and is capable of mounting a vigorous response upon reinfection with the same pathogen.
Enzyme produced in B cells undergoing a germinal center reaction that is required for mutating the variable region.
Activation-Induced Cytidine Deaminase (AID)
Enzyme released by NK cells that induces target cell apoptosis.
Antibody isotype that is most prevalent in the gut that can neutralize bacteria or toxins.
Term for a B or T cell proliferating in response to an antigen.
THIS SET IS OFTEN IN FOLDERS WITH...
D1 Survey of immune system
D1 Study Questions
D2 Study Questions
D3 Innate Immunity Study Questions
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