A pt presents with moderate allergic conjunctivitis x 2 weeks. He has tried benadryl-OTC, and Visine Orininal-OTC, but both have failed to relieve his symptoms. What is the drug therapy would be the most effective in relieving all of his symptoms, without referring his to opthalmology? Defend you answer.
Olopatadine (Patanol) (for the would be the most effective drug to prescribe in this situation.
As a combination of Opthalmic antihistamine and mast cell stabilizer, it would have the combined effect of reducing the current symptoms of itching, tearing, and swelling, plus provide future protecting by stabilizing the mast cell degranulation during subsequent allergen exposure.
Ketotifen (Zaditor) is another drug in this class, but it is an OTC drug and is less superior to Patanol.