Terms in this set (3)
Occurs when the inhibitor permanently impairs the enzyme (Covalent interactions). Bind very tightly to the enzyme-binding of the inhibitor to one of the R groups of an amino acid to the active site. This binding may block the active site binding groups so that the enzyme-substrate complex cannot form. (Ex: Snake venom, nerve gas)
Reversible, Competitive Inhibitors
-aka Structural analogs
-molecules that resemble the structure and change distribution of a natural substance for an enzyme. resemblance permits the inhibitor to occupy the enzyme site
-Inhibition is competitive because the inhibitor and substrate compete for binding to the active site
Reversible, Noncompetitive inhibitors
-Bind to an R group of an amino acid or to the metal ion cofactors
-binding is weak; enzyme activity is restored when inhibitor dissociates from the enzyme-inhibitor complex.
-These modify shape of the active site once bound elsewhere in structure; do not bind to active site.
OTHER SETS BY THIS CREATOR
Lipid Soluble vitamins and their coenzymes
H2O soluble vitamins & their coenzymes
Actions of eye muscles
THIS SET IS OFTEN IN FOLDERS WITH...
Structure of the cell
Bio 160 Chapter 1
Biology 160, week 1
Cell Communication (OpenStax Biology: Chapter 9)