12 terms

Chapter 10

CMV cytomegalovirus
DNA virus that accounts for many respiratory, ophthalmic, and liver infections
fusion inhibitor
a drug that prevents the fusion of the HIV-1 virus with the human cellular membrane, preventing it from entering the cell
helper T cell
human lymphocyte that helps initiate immune reactions on response to tissue invasion
hep B
serious to potentially fatal viral infection of the liver, transmitted by body fluids
retrovirus that attacks helper T cells, leading to a decrease in immune function and AIDS or ARC
influenza A
RNA virus that invades tissues of the respiratory tract, causing the signs and symptoms of the common cold ot "flu"
integrase inhibitor
a drug tha inhibits the activity of the virus-specific enzyme integrasem an encoded enzyme needed for viral replication, blocking this enzyme prevents the formation of the HIV-1 provirus
tissue hormone that is released in response to viral invasion, blocks viral replication
nonnucleoside reverse transcriptase inhibitors
drugs that bind to sites on the reverse transcriptase, preventing RNA- and DNA- dependent DNA polymerase activities needed to carry out the viral DNA synthesis; prevents the tranfer of information that allows the virus to replicate and survive
nucleoside reverse transcrpitase inhibitor
drugs that prevent the growth of the viral DNA chain, preventing it from inserting the host DNA, so viral replication cannot occur
protease inhibitors
drugs that block the activity of the enzume protease in HIV, proteast is essential for the maturation of infectious virus, and its absence leads to the formation of an immature and noninfective HIV particle
particle of DNA or RNA surrounded by a protein coat that survives by invading a cell to alter its functioning