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IPAP 1-15 Pharm 2 Exam 1 Review
Terms in this set (14)
23 year old diagnosed with schizo. She's seein' shit, says her parents are trying to get rid of her, smoked a pack a day since 16, hearing voices that say to kill herself. That's a general description. Forgot to take a pic of the set up for the question:
The medical team decides to initiate txt for the pt. Which of the following anti-psychotic meds is the best initial txt for this pt?
A. Haloperidol (Haldol)
B. Thioridazine (Mallari)
C. Clozapine (Clozaril)
D. Risperidone (Risperdal)
E. Nefazodone (Serzone)
Which anticonvulsive drug txt has a high incidence of kidney stones?
85 yo woman with Parkinson's dz currently being txt'ed with carbidopa/levodopa and dopamine agonist, but symptoms are worsening. She has normal liver function. Selegiline is added to her regimen. How does Selegiline work in Parkinson's?
A. Increase NE synthesis
B. Inhibit COMT
C. Inhibit MAO
D. Stimulate acetylcholine release
E. Stimulate NE release
Sometimes combo txt of Parkinsons is warranted. Which of the following drug combos could work cooperatively to enhance a clinical anti-parkinsonion response?
A. Amphetamin and ammantidine
B. Levodopa and Carbidopa
C. Amantadine and haloperidol
D. Dopamine and Tyramine
E. Quetiapine and dopamine
Levodopa and Carbidopa
30 yo man presents for management of neuropathic pain. Pain is tingling burning pain in extremities that did not respond to gabapentin. Past medical hx of depression, peripheral vascular dz, and diabetes. Recently dx'd with diabetic neuropathy. What is the best med to replace gabapentin to txt diabetic neuropathy that may also help txt his depression?
Which atypical neuroleptic/antipsychotic is reserved for pts who are resistant to other antipsychotics and is indicated to reduce the risk of suicide?
Little kid weighing 56 lbs is prescribed Phenytoin for his seizure disorder. Reference oral dose is 15 mg/kg/day in 3 divided doses. How many mLs of a 125 mg/5mL suspension do you need to prescribe per dose for him?
A. 5 mLs
B. 12 mLs
C. 15 mLs
D. 8 mLs
E. 10 mLs
Which of the following local anesthetics are less likely to cause systemic toxicity?
34 yo male with general tonic-clonic seizures. Currently taking phenytoin 300 mg QHS and experiencing 2-3 seizures per month. His labs from this morning reveal a serum concentration of 8 mcg/ml. You want his level closer to 15 mcg/ml. What dosage adjustments is the best option to make?
A. Continue phenytoin at this dose, check albumin and free phenytoin level
B. Double phenytoin dose to 600 mg QHS
C. Increase phenytoin dose to 400 mg QHS
D. Add valproic acid and gradually taper phenytoin
E. Add on of the new AED agents (lamotrigine/topiramate)
Continue phenytoin and check levels
Extrapyramidal symptoms are cause mainly by:
A. Stimulation of GABA receptors
B. Stimulation of dopamine receptors
C. Blockage of dopamine receptors
D. Blockage of serotonin receptors
E. Blockage of NE and Serotonin receptors
Blockage of dopamine receptors
Which of the following agents are classified as a serotonin, NE reuptake inhibitor (SNRI)?
132 lb lady, 18 years old needs needs to be sedated. The sedating loading dose of Midazolam is 0.05 mg/kg. Vial concentration you have of Midazolam is 4 mg/mL. How much do you give her?
A. 10 mL
B. 0.5 mL
C. 3 mL
D. 0.75 mL
E. 1.5 mL
132 lbx / 2.2 kg = 60 kg
0.05 mg/kg x 60 kg = 3 mg
4 mg / 1 mL = 3 mg / ? mL
Which of the following medications would most likely exacerbate a preexisting seizure disorder?
A 36 yo woman presents with a 2 month history of depressed mood, anhedonia (can't experience pleasure), increased appetite, weight gain, hyper somnolence, and suicidal ideation. This is the pt's 1st episode of major depression. Which of the following anti-depressants would be most appropriate in the txt of this pt?
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