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what are the requirements for a molecule to be immunogenic(immunogenicity requirements) Hint: there are 5
route and scheduled of immunization
use of adjuvants
What does size of the Ag have to do with the immune response?
The greater the size of the Ag, the larger the immune response
T or F, the more complex the antigen, the harder it is to mount an immune response
F, the more complex, the better the response
How are adjuvant limited in their ability to increase immunogenicity?
they cant make non-immunogenic compounds immunogenic
How do most adjuvants carry out their function(of increasing a compounds immunogenicity)?
they increase macrophage and helper t cell functions
What are thymic(t cell) dependent antigens and thymic(t cell) independent antigens?
They either do or do not stimulate T cells
T or F, thymic(t cell) independent antigens will not stimulate T cells but will stimulate b cells?
T or F, most T cell independent antigens are Commonly made of repeating units (ex.: carbohydrates, some polymers)
How can haptens become antigenic when they are conjugated to something immunogenic
They acts as epitopes
What is immunological cross reaction?
when an Ab semi reacts with an epitope on an Ag but not all of them. This Ag is not the right one to react fully with the Ab
T or F, When an Ab binds to an Ag epitope, the rxn is held together by covalent bonds
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