Histology Connective Tissue 2
Terms in this set (33)
4 functions of the ground substance
What are the two groups of ground substance?
Glycosaminoglycans (GAGs) and Glycoproteins
What are GAGs
Structural proteins bound to protein core to create a bottle brush structure
Name 2 types of GAGs
hyaluronic acid and the sulfates
Name 4 Glycoproteins
fibronectin, laminin, chondronectin, and integrins
What charge do the GAGs have?
highly negative because of the sulfate group
Explain how hyaluronic acid differs from the rest of the GAGs
longer chain and forms the base of the bottle brush that the core protein binds to
decribe a proteoglycan monomer
A bunch of GAGs around a central protein linked to hyaluronic acid.
What are the functions of the glycoproteins?
glue. stabilizes ECM and links it to the surface
Most abundant, 2 peptides linked with a disulfide bond
What is the function of fibronectin?
cell attachment to ECM
Where is laminin found?
What is the function of laminin?
binding site for GAGs so that it can create a mat holding the cell to the deeper tissue.
What shape is the laminin nucleus
What stain is used for glycoproteins?
What is the function of tissue fluid?
small amount of water for diffusion and solvation
Name the two types of embryonic CT
mesenchyme and mucous
Where is the mesenchyme?
in embryo and can become any type of cell
Where is the mucous CT present?
What is another name for Umbilical mucous CT?
What is the purpose of Whartons Jelly?
Prevents knotting of cord
What are the two types of CT proper?
Loose CT (Areolar) and Dense CT
Decribe loose CT
large number of cells, less fibers, highly vascularized=high metabolism
What are two types of Dense CT
Dense Regular and Dense Irregular
Descibe dense irregular CT
Fibers in an irregular fashion to resist stress in all directions. Mainly collagen and fibroblasts
Where is Dense Irregular CT found?
dermis, submucosa of GI
Describe Dense regular CT
Fibers oriented in one way to impact tensile strength
Where is dense regular CT found?
Tendons, ligaments, and aponeuroses
What is the endotendineum
CT around cell in tendon
What is the peritendineum
CT around group of cells in tendon
What is the epitendineum?
CT around the tendon
Waht are the 4 types of CT?
Reticular, Elastic, adipose, and specialized
What are the 3 types of specialized CT?
cartilage, bone, and blood