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13 terms

Pathophysiology Test 1 Chapter 10

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define the terms nutritional status and metabolism
nutritional status describes the condition of the body related to the availability and use of nutrients
metabolism is the organized process through which nutrients such as carbohydrates, fats, and proteins are broken down, transformed, or otherwise converted into cellular energy
define the term calorie and state the number of calories derived from the oxidation of 1 g of protein, fat, and carbohydrate
calorie is the amount of heat or energy required to raise the temperature of 1 g of water by 1 degree C
the oxidation of protein provides 4kcal/g; fats 9 kcal/g; carbohydrates 4kcal/g
calories in =
calories used + calories stored
caloric intake is controlled by
appetite
hunger and satiety centers in hypothalamus
calorie use is controlled by
metabolic rate
thyroid hormones
activity level
calories are stored in
adipose tissue
white adipose tissue
brown adipose tissue
90% of body energy stored as triglycerides in the fat cells of the body.

Brown adipose mostly NB and able to produce heat.
discuss the role of the hypothalamus in the control of energy intake
the hypothalamus contains the feeding center for hunger and satiety
it recieves neural input from the GI tract that provides information about stomach filling, chemical signals from nutrients in the blood, and input from the cerebral cortex regarding the smell, sight, and taste of food
adipose tissue
not just a resovior for energy storage
express and secrete bioactive peptides
energy metabolism
neuroendocrine function
immune function
chronic inflammatory response
abnormal cytokine production
increase c reactive protein
type 2 diabetes
list the major causes of malnutrition and starvation
poverty
lack of knowledge
acute and chronic illness
self imposed dietary restriction
upper and lower body obesity
Two types of obesity based on distribution of fat
Upper body: central, abdominal, or visceral

Lower body: peripheral or gluteal-femoral.

Determined by dividing the waist by the hip circumference. Waist to hip ratios greater than 1.0 in men or 0.8 in women
marasmus
too few calories in diet
too little protein in diet
progressive loss of muscle mass and fat stores due to inadequate food intake that is equally deficient in calories and protein
child with marasmus has a wasted appearance with loss of muscle mass stunted growth and loss of subcutaneous fat; a protruding abdomen (from muscular hypotonia)wrinkled skin sparse dry and dull hair and depressed heart rate blood pressure and body temp diarrhea is common
kwashiorkor
adequate calories in diet
too little protein in diet
more severe form of malnutrition
severe loss of the viscera protein compartment with a resultant hypoalbuminemia that gives rise to generalized or dependent edema
state the causes of malnutrition in trauma and illness
in persons with severe injury or illness net protein breakdown is accelerated and protein rebuilding disrupted. protein mass is lost from the liver, GI tract, kidneys, and heart. as protein is lost from the liver, hepatic synthesis of proteins declines and plsma protein levels are decreased
there also is a decrease in immune cells
wound healing is poor, and the body is unable to fight off infection bc of multiple immunologic malfunctions throughout the body