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5 Written questions

5 Matching questions

  1. PIPERACILLIN Nursing implications -
  2. AMPICILLIN Action -
  3. PENICILLIN G or V Contraindications -
  4. AMOXICILLIN side effects are
  5. CEFTRIAXONE Action -
  1. a intermittent infusion ; s/s of anaphylaxis
  2. b Bind to bacterial cell wall, resulting in cell death; Broad spectrum
  3. c Previous hypersensitivity to penicillin
  4. d d/n/v/r, seizures (high Doses), increase liver enzymes, urticaria, blood dyscrasias, anaphylaxis, serum sickness, superinfection
  5. e Action - Binds to the bacterial cell wall membrane, causing cell death; Bactericidal action against susceptible bacteria; Similar to that of second-generation cephalosporins, but activity against staphylococci is less, while activity against gram-negative pathogens is greater, even for organisms resistant to first- and second-generation agents. Notable is increased action against.

5 Multiple choice questions

  1. Use - Treatment of. Respiratory tract infections, Skin and skin structure infections, Bone and joint infections (IV), Urinary tract infections, Gynecological infections, Septicemia (IV), Otitis media (PO), Meningitis (IV), Lyme disease (PO); Perioperative prophylaxis (IV).
  2. Hypersensitivity to cephalosporins.
    • Serious hypersensitivity to penicillins.
    • Pedi: Neonates 28 days (use in hyperbilirubinemic neonates may lead to kernicterus).
    • Pedi: Neonates 28 days requiring calcium-containing IV solutions ( risk of precipitation formation).
  3. Nursing implications- IV; IM; Intermittent infusion
  4. Binds to bacterial cell wall membrane, causing cell death; Bactericidal action against susceptible bacteria. Similar to that of first-generation cephalosporins but has increased activity against several other gram-negative pathogens
  5. Hypersensitivity to penicillins, beta-lactams, cephalosporins, or tazobactam (cross-sensitivity may occur

5 True/False questions

  1. CIPROFLOXACIN Contraindictions -Hypersensitivity (cross-sensitivity within class may exist).
    • OB: Do not use unless potential benefit outweighs potential fetal risk.
    • Pedi: Use only for treatment of anthrax and complicated urinary tract infections in children 1-17 years due to possible arthropathy

          

  2. AUGMENTIN (Amoxicillin/Clavulanate) Action-Binds to bacterial cell wall, causing cell death; spectrum of amoxicillin is broader than penicillin. Clavulanate resists action of beta-lactamase, an enzyme produced by bacteria that is capable of inactivating some penicillins; Bactericidal action against susceptible bacteria

          

  3. LEVOFLOXACIN useAction - Inhibits bacterial DNA synthesis by inhibiting DNA gyrase enzyme.; Death of susceptible bacteria; Active against gram-positive pathogens, including. › Staphylococcus aureus.
    › Staphylococcus epidermidis.
    › Staphylococcus saprophyticus.
    › Streptococcus pyogenes.
    › Streptococcus pneumoniae.
    › Enterococcus faecalis.
    › Bacillus anthracis.
    Gram-negative spectrum notable for activity against. › Escherichia coli.
    › Klebsiella pneumoniae.
    › Enterobacter cloacae.
    › Proteus mirabilis.
    › Pseudomonas aeruginosa.
    › Serratia marcescens.
    › Haemophilus influenzae.
    › Moraxella catarrhalis.
    Additional spectrum includes. › Chlamydophylia pneumoniae.
    › Legionella pneumoniae.
    › Mycoplasma pneumoniae.

    Use- PO, IV: Treatment of the following bacterial infections. › Urinary tract infections, including cystitis, pyelonephritis, and prostatitis.
    › Respiratory tract infections, including acute sinusitis, acute exacerbations of chronic bronchitis, community-acquired pneumonia, and nosocomial pneumonia.
    › Uncomplicated and complicated skin and skin structure infections.
    • Post-exposure treatment of inhalational anthrax

    Side Effect -d/n/v/r; seizures, dizziness, drowsiness, headache, insomnia, agitation, confusion, QTc prolongation, arrhythmias, hepatotoxicity, pseudomembranous colitis, abdomininal pain, vaginitis, photosensitivity, hyper/hypeglcemia, phlenbitis @IV site, peripheral neuropathy, arthralgia, tendinitis, tendon rupture, anaphylaxis

    Contraindictions - Hypersensitivity (cross-sensitivity within class may exist).
    • Pedi: Children <18 yr [except for inhalational anthrax (post-exposure)].
    • OB: Pregnancy.

    Nursing implications - PO; intermittent infusion

    Trade / Generic Name - Levaquin

    Classification - Fluoroquinolones; anti-infectives

    Dosage: Most infections PO 250-750 mg q 24hrs
    Inhalation Anthrax 500mg daily for 60 days

          

  4. CIPROFLOXACINPO, IV: Treatment of the following bacterial infections. › Urinary tract infections, including cystitis, pyelonephritis, and prostatitis.
    › Respiratory tract infections, including acute sinusitis, acute exacerbations of chronic bronchitis, community-acquired pneumonia, and nosocomial pneumonia.
    › Uncomplicated and complicated skin and skin structure infections.
    • Post-exposure treatment of inhalational anthrax

          

  5. GENTAMICIN Contraindictions -Hypersensitivity to gentamicin or other aminoglycosides.
    • Most parenteral products contain bisulfites and should be avoided in patients with known intolerance.
    • Pedi: Products containing benzyl alcohol should be avoided in neonates.