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5 Written questions

5 Matching questions

  1. AMPICILLIN Nursing implications -
  2. CEFTRIAXONE use
  3. CEFTRIAXONE Contraindictions -
  4. AMOXICILLIN Action -
  5. Oxacillin Use
  1. a Hypersensitivity to cephalosporins.
    • Serious hypersensitivity to penicillins.
    • Pedi: Neonates 28 days (use in hyperbilirubinemic neonates may lead to kernicterus).
    • Pedi: Neonates 28 days requiring calcium-containing IV solutions ( risk of precipitation formation).
  2. b Treatment of. Skin and skin structure infections.
    › Bone and joint infections.
    › Complicated and uncomplicated urinary tract infections.
    › Uncomplicated gynecological infections including gonorrhea.
    › Lower respiratory tract infections.
    › Intra-abdominal infections.
    › Septicemia.
    › Meningitis.
    › Otitis media.
    Perioperative prophylaxis
  3. c Binds to bacterial cell wall, causing cell death; bactericidal action; spectrum is broader than penicillins
  4. d IM / IV use for moderately severe to severe infections; change to PO asap; s/s anaphylaxis & monitor bowl functions
  5. e Respiratory tract infections, sinusitis, skin & skin structure infections , bone & joint infections, urinary tract infection , endocardistis, bacterium, meningitis

5 Multiple choice questions

  1. - d/v/n/r urticaria, seizures(high doses) pseudomembranous colitis, hepatic dysfunction, vaginal candidiasis, blood dycrasias, allergic reactions including anaphylaxis & serum sickness, superinfection
  2. skin & skin structure infections, soft-tissue infections, otitis media, sinusitis, respiratory infections, genitourinary infections, meningitis, septicemia. Endocarditis prophylaxi
  3. Action - Binds to the bacterial cell wall membrane, causing cell death; Bactericidal action against susceptible bacteria; Similar to that of second-generation cephalosporins, but activity against staphylococci is less, while activity against gram-negative pathogens is greater, even for organisms resistant to first- and second-generation agents. Notable is increased action against. › Acinetobacter.
    › Enterobacter.
    › Haemophilus influenzae (including -lactamase-producing strains).
    › Haemophilus parainfluenzae.
    › Escherichia coli.
    › Klebsiella pneumoniae.
    › Morganella morganii.
    › Neisseria.
    › Proteus.
    › Providencia.
    › Serratia.
    › Moraxella catarrhalis.
    Has some activity against anaerobes, includingBacteroides fragilis .

    Use - Treatment of. › Skin and skin structure infections.
    › Bone and joint infections.
    › Complicated and uncomplicated urinary tract infections.
    › Uncomplicated gynecological infections including gonorrhea.
    › Lower respiratory tract infections.
    › Intra-abdominal infections.
    › Septicemia.
    › Meningitis.
    › Otitis media.
    Perioperative prophylaxis

    Side Effect - sezures (High doses), pseudomembranous colitis, d/, cholelithaiasis, gallbladder sludging, rashes, urticaria, bleeding, eosinophilia, hemolytic anemia, leucopenia, thrombocytosis, pain @ IM site, phlebitis at IV site, anaphylaxis, superinfection

    Contraindictions - Hypersensitivity to cephalosporins.
    • Serious hypersensitivity to penicillins.
    • Pedi: Neonates 28 days (use in hyperbilirubinemic neonates may lead to kernicterus).
    • Pedi: Neonates 28 days requiring calcium-containing IV solutions ( risk of precipitation formation).

    Nursing implications- IV; IM; Intermittent infusion

    Trade / Generic Name - Rocephin

    Classification - 3rd Generation cephalosporins; anti-infectives

    Dosage: IM/IV 1-2gm q 12-24hr most infections
    IM 250mg-Gonorehea
    2gm q 12hrs
  4. Hypersensitivity (cross-sensitivity within class may exist).
    • OB: Do not use unless potential benefit outweighs potential fetal risk.
    • Pedi: Use only for treatment of anthrax and complicated urinary tract infections in children 1-17 years due to possible arthropathy
  5. Binds to bacterial cell wall membrane, causing cell death; Bactericidal action against susceptible bacteria. Similar to that of first-generation cephalosporins but has increased activity against several other gram-negative pathogens

5 True/False questions

  1. CEFAZOLIN useAction - Binds to bacterial cell wall membrane, causing cell death; Bactericidal action against susceptible bacteria; Active against many gram-positive cocci including. (Streptococcus pneumonia, Group A beta-hemolytic streptococci. , Penicillinase-producing staphylococci) Active against some gram-negative rods including(Proteus mirabilis & Escherichia coli)

    Use - Treatment of the following infections due to susceptible organisms, Skin and skin structure infections (including burn wounds). Pneumonia, Urinary tract infections, Biliary tract infections, Genital infections, Bone and joint infections, Septicemia, Bacterial endocarditis prophylaxis for dental and upper respiratory procedures; Perioperative prophylaxis

    Side Effect - d/n/v/r; seizures(high doses), pseudomembranous colitis, cramps, Stevens-Johnson Syndrome, Pruritis, urticaria, leucopenia, neutropenia, thrombocytopenia, pain at IM site, phlebitis at IV site, anaphylaxis serum sickness, superinfection

    Contraindictions - Hypersensitivity to cephalosporins, Serious hypersensitivity to penicillins

    Nursing implications - IM / IV; observe for s/s of anaphylaxis & monitor bowel function

    Trade / Generic Name - Ancef

    Classification - First Generation cephalosporins; anti- infectives

    Dosage IM/IV 500mg - 2gm q 6-8 hrs max 12gm/day
    Mild infection with gram positive cocci 250-500mg q
    8hrs
    Pneumonia 500mg q 12hrs

          

  2. PIPERACILLIN Action -Binds to bacterial cell wall membrane, causing cell death. Spectrum is extended compared with other penicillins; Death of susceptible bacteria( active against piperacillin-resistant, beta-lactamase-producing)

          

  3. GENTAMICIN Contraindictions -Hypersensitivity to gentamicin or other aminoglycosides.
    • Most parenteral products contain bisulfites and should be avoided in patients with known intolerance.
    • Pedi: Products containing benzyl alcohol should be avoided in neonates.

          

  4. AUGMENTIN (Amoxicillin/Clavulanate) Contraindictions -Nursing implications - PO(Administer at the start of a meal to enhance absorption and to decrease GI side effects. Do not administer with high fat meals; clavulanate absorption is decreased.)

          

  5. AMOXICILLIN Nursing implications -PO ; Less GI distress than Ampilicin; s/s anaphylaxis, Monitor bowl function