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5 Written questions

5 Matching questions

  1. GENTAMICIN Action -
  2. AMPICILLIN side effects are
  3. OXACILLIN Nursing Implications -
  4. LEVOFLOXACIN Nursing implications
  1. a Action - Inhibits protein synthesis in bacteria at level of 30S ribosome; Bactericidal action; Notable for activity against. › Pseudomonas aeruginosa.
    › Klebsiella pneumoniae.
    › Escherichia coli.
    › Proteus.
    › Serratia.
    › Acinetobacter.
    › Staphylococcus aureus.
    In treatment of enterococcal infections, synergy with a penicillin is required.

    Use- Treatment of serious gram-negative bacterial infections and infections caused by staphylococci when penicillins or other less toxic drugs are contraindicated.
    • In combination with other agents in the management of serious enterococcal infections.
    • Prevention of infective endocarditis.
    • Topical, Ophth: Treatment of localized infections due to susceptible organisms.

    Side Effect - ataxia, vertigo, ototoxicity(vestibulare & cochlear) nephrotoxiticy, muscle paralysis(high parenteral doses); hybersensitivyt reactions

    Contraindictions - Hypersensitivity to gentamicin or other aminoglycosides.
    • Most parenteral products contain bisulfites and should be avoided in patients with known intolerance.
    • Pedi: Products containing benzyl alcohol should be avoided in neonates.

    Nursing implications - Keep patient well Hydrated, IM; Intermittent infusion; topical
    Evaluate 8th cranial nerve function, I/O, assess for superinfection

    Trade / Generic Name - Garamycin, G-Mycin, Jenamicin

    Classification - Aminoglycosides; anti-infectives

    Dosage: IM/IV 1-2mg/kg q 8hrs up to 6mg/kg a day in 3 divided doses
  2. b Seizures(high doses) pseudomembranous colitis, d/n/v/r, urticaria, blood dysrasias, anaphylaxis serum sickness, superinfection
  3. c PO; intermittent infusion
  4. d IM, IV, & intermittent Infusion; Observe for signs & symptoms of anaphylaxis
  5. e Inhibits protein synthesis in bacteria at level of 30S ribosome; Bactericidal action; Notable for activity against. ›

5 Multiple choice questions

  1. skin & skin structure infections, otitis media, sinusitis, respiratory infections, genitourinary infections, endocarditis prophylaxis, postexposure inhalational anthrax prophylaxis, mgmt of ulcer disease due to Helicobacter pylori
  2. Nursing implications - PO, admin with food; IM/IV, Direct IV, Intermittent infusion
  3. Appendicitis and peritonitis, Skin and skin structure infections, Gynecologic infections, Community-acquired and nosocomial pneumonia caused by piperacillin-resistant, beta-lactamase-producing bacteria.
  4. Action - bind to bacterial cell wall, leading to cell death; Inactivated by penicillinase enzyme; Gram positive aerobic cocci

    Use - Respiratory tract infections, sinusitis, skin & skin structure infections , bone & joint infections, urinary tract infection , endocardistis, bacterium, meningitis

    Side Effects - seizures, Nephritis, urticaria, allergic reaction ; Pain @ IM Site

    Contraindictions - Previous hypersensitivity to penicillin; Cross sensitivity with cephaloporins & beta lactam antibiotics

    Nursing Implications - IM, IV, & intermittent Infusion; Observe for signs & symptoms of anaphylaxis

    Trade / Generic Name - Bactocill

    Classification: Penicillinase resistant penicillins, Anti-infectives

    Dosage:Moderate Infection 250-500mg IM/IV q 4-6hrs
    Serve Infection 1-2gm IM/IV q 4-6hrs
  5. Bind to bacterial cell wall, resulting in cell death; Broad spectrum

5 True/False questions

  1. CIPROFLOXACIN side effects areSeizures, dizziness, drowsiness, headache, insomnia, agitation, confusion, d/n/r , pseudomembranous colitis, abdominal pain, abnormal liver enzymes, vaginitis, photosensitivity, hyperglycemia, hypoglycemia, eosinophilia, phlebitits at IV site, tendinitis, tendon rupture, peripheral neuropathy, anaphylaxis


  2. PIPERACILLIN side effects are- d/n/v/r/ constipation, drug induced hepatitis, confusion dizziness, headache, insomnia, lethargy, interstitial nephritis, bleeding ,leucopenia, neutropenia, thrombocytopenia, pain, phlebitis at IV site; hypersensitivity reactions, serum sickness, fever(increase in cystic fibrosis patients), superinfection


  3. CEFUROXIME Action -Binds to bacterial cell wall membrane, causing cell death; Bactericidal action against susceptible bacteria. Similar to that of first-generation cephalosporins but has increased activity against several other gram-negative pathogens


  4. LEVOFLOXACIN contraindictionsHypersensitivity (cross-sensitivity within class may exist).
    • Pedi: Children <18 yr [except for inhalation anthrax (post-exposure)].
    • OB: Pregnancy.


  5. CIPROFLOXACIN Nursing implications -Nursing implications - IM / IV; observe for s/s of anaphylaxis & monitor bowel function


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