University of Michigan Winter '12
Where Aristotle believed mental experiences arose
Where Plato believed mental experiences arose
The belief that the mind and body are made up of different kinds of substance.
Dual Aspect Theory
The belief that the mind and body are two levels of explanation of the same thing.
The belief that the mind-based concepts will eventually be replaced by neuroscientific concepts.
Early anatomists believed that mental experiences were enabled by this part of the brain.
The failed idea that individual differences in cognition can be mapped on to differences in skull shape.
The accurate view that different regions of the brain serve different functions.
A patient with a lesion in this region might not be able to speak but would otherwise have good cognitive abilities.
A patient with a lesion in this region might have poor speech comprehension but good speech production.
The goal of this area of study is to provide a brain-based account of how cognitive and emotional processes operate.
This dimension tells us when a brain even occurs.
This dimension tells us where a brain event occurs.
The view that the heart is the seat of the soul/mind
The view that the brain is the seat of the soul/mind.
Galen of Pergamon
Doctor who found that a) perception of the world involves the brain b) the brain is probably the center of all intellect/mental faculties and c) sensation can be dissociated from perception.
Circle of Willis
An english physician, who studied brain anatomy, discovered this. A circle of arteries that supplied the brain with blood
The proposed view that different parts of the brain performed different functions. Includes discoveries of Broca and Wernicke's areas
A map of this shows that different sections stimulate different body movements.
A map of this shows that different sections stimulate different somatic sensations.
The study of differences in cortical layers between areas
A task invented in which a subject sees a list of words (color terms) printed in an ink color that differs from the word named. The subject is asked to name the ink colors of the words in the list and demonstrates great difficult in doing so. Early use of subtraction method
This term means that one can't attend to too many things at once or else you'll get overloaded.
Meaning "above," sometimes referred to as superior
Meaning "front," sometimes referred to as frontal or rostral
Meaning "below" or "belly," sometimes referred to as inferior
Meaning "tail," sometimes referred to as caudal
The brain's outer layer; gray matter.
Valleys in the brain surface; banks and fundus
Peaks in the brain surface
This sulcus divides the brain into two cerebral hemispheres
This term means "hard body" and was once thought to structurally support the two hemispheres of the brain
This sulcus separates the temporal lobe from the parietal lobe and frontal lobes.
This sulcus separates the parietal lobe from the occipital lobe.
Humans are this. Means that our sense of smell is relatively poor compared to most mammals.
This area of the brain interprets smells.
This area is at the bottom of the Sylvian Fissure and contains the primary taste cortex. Also plays a role in emotional processing.
You will find the auditory cortex by this gyrus.
This gyrus contains the motor cortex, which controls movement
This gyrus contains the somatosensory cortex, which controls somatic sensation
Means same side
Where some of the optic nerve fibers cross
This analyzes motion, spatial relations and how to interact with objects. Stems from the primary visual cortex.
This analyzes form, color and object recognition. Stems from the primary visual cortex.
Processes almost all sensory information (except olfactory) that passes through various nuclei on its way to the cerebral cortex. Motor information also passes through here.
Regulates bodily functions/needs, such as temperature, eating and drinking, sexual activity and regulation of endocrine functions.
A neural system (including the hippocampus, amygdala, and hypothalamus) located below the cerebral hemispheres; associated with emotions and drives.
This area houses the superior and inferior colliculi, which participate in subcortical routes for hearing (inferior) and gaze orienting/rudimentary vision (superior)
This area houses the pons, medulla and cerebellum.
This area of the brain integrates information about body and motor commands to produce coordinated movements (no direct control over movement).
This type of cell acts as a support system for neurons, insulates axons with myelin, removes debris following injury or cell death and aids in the maintenance of extracellular ions and neurotransmitters.
There are about 100 billion of these in the brain. They underlie cognition.
This scientist developed a stain that allowed visualization of individual neurons, and believed the brain was a continuous mass of tissue with a common cytoplasm.
The Neuron Doctrine
This idea was developed after using Golgi's stain to show that the brain was made up of individual nerve cells linked together by long extensions.
This part of the neuron receives inputs.
This part of the neuron is the cell body; it carries out basic cell functions.
This place in the neuron integrates the action of all receptor potentials and triggers an action potential if some critical threshold is surpassed.
This part of the neuron transmits action potential.
This is a fatty substance of a neuron that insulates the axon and allows faster conduction of action potentials.
This part of the neuron contains vesicles filled with neurotransmitter molecules; released into the synapse when an action potential occurs and bind with receptors on the post-synaptic cell.
Where neurotransmitters are released after an action potential reaches the axon terminal.
A positive post-synaptic potential
A negative post-synaptic potential
Typically sensory cell; Example: hair cell in ear is perturbed by vibrations and has local effect on local permeability of membrane to ions.
The local interactions between cells; Example: one cell, the presynaptic cell influences the postsynaptic cell by the release of NT into the cleft
The process of creating an action potential by a rapid influx of Na+ through voltage gated ion channels.
A neural impulse; a sudden change (depolarization and repolarization) in the electrical properties of the neuron membrane in an axon.
Incoming bit of information that has local effect on membrane potential that spreads. Graded, decays over space.
This phase is where the action potential triggers the release of chemicals into the synaptic cleft.
Term for the number of action potentials propagated per second that varies along a continuum.
Regional Functional Specialization
Term meaning neurons that respond to similar types of information tend to be grouped together.
A way to identify neural connection
This is injected into axon terminals and travels back to the cell body.
This is injected into the cell body and travels to terminals.
The view that in between the stimulus and response there are many processes of the brain that occur.
The use of response time to infer the content, duration, and sequencing of cognitive processes
The idea that the time needed to complete a task consists of the time it takes to perceive the stimulus plus the time it takes to generate the response.
Means that people are faster at performing the same operation several times in a row than at switching operations.
This is the assumption that adding a new cognitive process does not affect the process underlying the existing task.
Another way to test stage models of cognition. If two factors influence DIFFERENT stages they should produce this type of effects on response time.
Another way to test stage models of cognition. If two factors influence the SAME stage, they should produce this type of effects on response time.
This method records neural activity directly; it counts the number of APs/second. It is invasive but provides excellent spatial and temporal resolution.
Type of neural representation; all of the information is carried by just one of the neurons in a given population cell.
Type of neural representation; all of the information is carried by all of the neurons in a given population.
Type of neural representation; all of the information is carried by a small proportion of the neurons in a given population
This type of coding provides a greater degree of response used to code information.
This type of coding provides a greater synchrony of response used to code information.
Summed Electrical Potentials
EEG picks up what on the scalp surface from millions of neurons?
EEG measures __________ __________ at the scalp surface that result from dendritic currents in large populations of neurons.
large, in parallel
To measure EEG signals 1) current must be flowing in dendrites of a _____ number of neurons, and 2) the neurons need to be positioned _________ with one another so the currents sum rather than cancel.
The Inverse Problem
Trying to determine which brain regions give rise to a particular scalp distribution of EEG signals.
EEG has fantastic __________ ________
Event Related Potentials
This is an average voltage change to a stimulus or event across time
Frequency analysis can help you determine what about the patient?
The series of positive and negative voltage deflections in an event-related potential
Early peaks of ERPs may approximately reflect the functioning of what process?
Later peaks of ERPs may approximately reflect the functioning of what process?
This method picks up magnetic signals on the scalp surface that stem from dendritic currents in large populations of neurons.
Where the neurons are located that MEG picks up on
This type of neuroimaging uses x-rays to create a 3D image of the brain
In a CT scan, high density tissue appears this color
In a CT scan, low density tissue appears this color
This type of imaging looks at the tilt protons in water-based hydrogen using a strong magnetic field.
DTI (Diffusion Tensor Imaging)
This type of neuroimaging measures the density and motion of water that travels along myelin covered axons. Creates images of white matter tracts in the brain.
VBM (Voxel-Based Morphometry)
MRI-based method for calculating the density of grey and white matter in each 3D pixel of a brain scan
PET (Positron Emission Tomography)
This type of neuroimaging measures local variations in blood flow which corresponds to the level of activity in a brain region; requires the injection of a radioactive isotope into the blood stream
Researchers use this to contrast brain activity in two different task conditions during PET
This type of neuroimaging is an indirect measure of neural activity. Its based on fact that oxygenated and deoxygenated blood have different magnetic properties.
This fMRI design measures the hemodynamic response to each stimulus in an experiment.
In lesioning, when function A is present and function B is absent in one person, and function A is absent and function B is present in another. Means that the two functions involve different mechanisms and operate independently of one another.
fMRI is used to measure what between brain regions during the performance of a task?
Volume, Oxygen Concentration
PET is based on blood _______, where as fMRI is based on blood _____________
This type of study tries to infer the mental process that a brain region supports by observing what mental process is disrupted when the region no longer functions properly.
A possible cause of a stroke. Hardening of arteries most commonly caused by a buildup of plaque on artery walls.
A possible cause of a stroke. A weak, bulging spot on an artery wall and is prone to suddenly expand or burst, disrupting blood supply.
Common type of brain tumor. Its a tumor of white matter, glia cells.
Occurs when a focal lesion impairs one cognitive process while leaving another relatively intact.
Potential explanation for a single dissociation. Maybe the impaired task is just harder
Potential explanation for a single dissociation. Maybe the patient failed to understand the instructions for the impaired task.
Assumption of single case studies - focal brain damage can produce selective cognitive deficits.
Assumption of single case studies - brain damage can affect one or more components within the cognitive system, but does not result in an entirely new cognitive system being created.
Assumption of single case studies - all cognitive systems are essentially the same.
This form of neuropsychology uses lesions to infer the functions of specific brain regions and is thus very concerned with lesion location. Uses group study methodologies.
Type of lesion-deficit association - this type of grouping can be useful for investigating the neural correlates of a disease pathology but not for dissecting cognitive theory.
by Behavioral System
Type of lesion-deficit association - this type of grouping can potentially identify multiple regions that enable a cognitive process
by Lesion Location
Lesion-deficit association - this type of grouping can be useful for testing predictions derived from functional imaging.
Method of temporary lesioning that disrupts neurons to trigger associated behaviors and reveal what "behaviors" might be lost if the neurons were damaged.
TMS (Transcranial Magnetic Stimulation)
Method of temporary lesioning where an magnetic field is created to induce a current in the nearby neurons and disrupt the cognitive function that may be happening at that point in time.
Type of TMS that can measure altered performance on a behavioral task for several minutes after stimulation ends. Used to treat depression.
Single or Paired-Pulse
Type of TMS involves delivering pulses at one or more times during a trial to then measure effects of TMS on behavior with relatively high temporal resolution.
Temporarily lesioning a brain region could actually lead to what, for competing brain regions?
Lesions identify areas ____________ for a function.
PET and TMS
Which two methods would you use to see what the "visual" cortex of a blind person
An approach in which behavior is described in terms of a sequence of cognitive stages.
This term means that later stages of processing can being before earlier stages are complete.
Computational models in which information processing occurs using many interconnected nodes.
The notion that certain cognitive processes (or regions of the brain) are restricted in the type of information they process.
The idea that a cognitive process (or brain region) is dedicated solely to one particular type of information.
Regions of cortex defined by the relative distribution of cell types across cortical layers (cytoarchitecture).
Regions of subcortical gray matter involved in aspects of motor control and skill learning; they consist of structures such as the caudate nucleus, putamen and globus pallidus
A midbrain nucleus that forms part of a subcortical sensory pathway involved in programming fast eye movements.
A midbrain nucleus that forms part of a subcortical auditory pathway.
This type of electrophysiology recording uses the electrical activity (in terms of APs/sec) of many individually recorded neurons.
A hypothetical neuron that just responds to one particular stimulus
Additive Factors Method
A general method for dividing reaction times into different stages devised by Sternberg.
Associative Priming (semantic priming)
A term meaning reaction times are faster to a stimulus if that stimulus is preceded by a stimulus of similar meaning (RADIO and radio)
Term meaning related to properties of the stimulus
Term meaning related to properties of the task
An attempt to solve the invers problem in ERP research that involves assuming how many regions of electrical activity contribute to the signal recorded at the scalp.
HRF (Hemodynamic Response Function)
Changes in the BOLD signal over time.
The mapping of individual differences in brain anatomy onto a standard template.
Redistributing brain activity from neighboring voxels to enhance the signal-to-noise ratio.
A surgical procedure in which fibers of the corpus callosum are severed
Terms meaning difficulties in spelling and writing.
A term meaning swelling of the brain following injury
A term meaning discrete brain lesion can disrupt the functioning of distant brain regions that are structurally intact.
Cognitive neuroscience in non-human animals
LGN (Lateral Geniculate Nucleus)
Information from the left and right visual fields synapses on this region before continuing to the primary visual cortex
Type of agnosia where there is a failure to understand the meaning of objects due to a deficit at the level of object perception.
Type of agnosia where there is a failure to understand the meanings of objects due to a deficit at the level of semantic memory.
Descartes believed that the soul interacted with this brain region.
If someone dissected a brain to separate the right and left hemisphere, what type of "slice" would this be?
BCI (Brain-Computer Interface)
This technique allows computers to use patterns of electrical activity as input.
This technique involves inserting specific proteins into rats' brains, which turns certain neurons on with specific colors of light.
This theory thinks that regardless of where a lesion is made, an animal will recover or show no deficits in performance.