Week 3: Headache

Drug interaction and effect between acetaminophen and alcohol
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Terms in this set (21)
Drug interaction and effect between acetaminophen and alcohol
Increased risk of hepatotoxicity
Drug interaction and effect between acetaminophen and warfarin
Increased risk of bleeding (elevations in INR) respectively
Drug interaction and effect between aspirin and valproic acid
affect protein binding and inhibit valporic acid metabolism
Drug interaction and effect between NSAIDs including COX inhibitors
Increased risk of gastroduodenal ulcers and bleeding
Drug interaction and effect between ibuprofen and aspirin
decrease antiplatelet effect of aspirin
Drug interaction and effect between ibuprofen and phenytoin
displacement from protein binding sites
Drug interaction and effect between several NASIDs and bisphosphonates
increase risk of GI esophageal ulceration
Drug interaction and effect between several NSAIDs and digoxin
renal clearance of digoxin inhibited
Drug interaction and effect between salicylates and NSAIDs with anticoagulants
increase risk of bleeding especially in the GI
Drug interaction and effect between salicylates and NSAIDs and alcohol
increase risk of GI bleeding
Drug interaction and effect between salicylates and NSAIDs with methotrexatedecreased methotrexate clearanceDrug interaction and effect between salicylates and sulfonulureasincrease risk of hypoglycemiaat what age does reye's syndrome usually occur?children 15 and youngerWho should not be given ASA to decrease risk of Reyes syndromeAspirin and other salicylates (including bismuth subsalicylate and nonaspirin salicylates) should be avoided in children and teenagers who have influenza or chickenpoxchoice of drug for kids 2 year and older for headache?acetaminophen or ibuprofechoice of drug for children 12 yo and upnaproxento avoid reye's syndrome in children what drug should we use?aspirin or aspirin-containing products children 15 and underchoice of drug for older adultsacetaminophen to avoid GI toxicitychoice of drug for pregnant womenacetaminophenchoice of drug for lactating women2.4 g of ibuprofen / day naproxenWhat drug(s) should patients avoid in last trimester of pregnancy and why?aspirin