14 terms

Ch 1: History

Francesco Redi
Disproved spontaneous generation by demonstrating that maggots developed without access to meat.
Louis Pasteur
Disproved spontaneous generation by using swan-shaped flask that prevented dust particles from contaminating broth.
Robert Hooke
provided the earliest record of microbes using his single lens microscope; author of "Micrographia"
Antonie Leeuwenhoek
Expanded on Hook's observations; Constructed hundreds of microscopes; Considered the "Father of Microbiology"
John Tyndall
Developed process of "Tyndallization" by use of a Tyndall Box coated with glycerin to catch any floating bacteria in the air; Used urine flasks to demonstrate the use of a Tyndall Box; Stated that some microbes have very high heat resistance
Ferdinand Cohn
Discovered heat resistant bacterial ENDOSPORES, which explained why boiling did not always eliminate all microorganisms.
Robert Koch
Linked microscopic organisms with disease by studying anthrax, which he infected mice with; Developed Koch's Postulates
Ignaz Semmellueis
Showed that women became infected in the maternity ward after examinations by physicians coming directly from the autopsy room.
Joseph Lister
Introduced aseptic techniques to keep the medical setting more sterile.
John Needham
Proposed to test whether or not microorganisms appeared spontaneously after boiling; boiled chicken broth, put it into a flask, sealed it, and waited...microorganisms grew; claimed victory for spontaneous generation
Lazzaro Spallanzani
Suggested that microorganisms were still able to enter the flask in Needham's experiment; modified Needham's experiment by placing chicken broth in a flask, sealed flask, drew off the air to create a vacuum, then boiled broth...no microorganisms grew!
Hooke, Leeuwenhoek
Who demonstrated that microbes exist?
Cohn, Pasteur, Tyndall
Who demonstrated that bacteria reproduces rather than spontaneously generates?
Robert Koch
Who demonstrated that microbes are responsible for diseases?