6 Canine Melanoma

Term

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what is the tissue origin for melanomas?

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Terms in this set (17)

what is the tissue origin for melanomas?

mesenchymal

note: also has characteristics of round cell tumors, somewhat epithelial and neuroendocrine too

T/F Melanoma is the most common oral tumor in dogs

TRUE

Dobies and mini Schnauzers tend to have (higher/lower) grade melanomas.

Poodles tend to have (higher/lower) grade melanomas.

dobies, schnauzers: lower grade, more benign

poodles: higher grade, more malignant

T/F Skin melanomas are caused by excessive UV exposure

FALSE

Your patient has an oral melanoma. You know how important it is to aspirate regional LNs (submandibular) when staging melanomas because they met there so frequently. You look at the aspirate on a slide and see cells with pigment in them. You decide to send them to the pathologist, because you're not sure if they're melanoma cells or if they're ____

melanophages

(macrophages that ate pigment that wandered outside of cells; these are commonly found in submandibular LNs of dogs with highly pigmented mouths)

T/F Melanoma grade predicts outcome

TRUE

EXAM Q
Describe oral melanoma staging:
Stage I
Stage II
Stage III
Stage IV

Stage I - <2cm tumor, node negative
Stage II - tumors 2-4cm diameter, node negative
Stage III - >4 cm tumor and/or positive nodes
Stage IV - distant metastatic disease (liver, lung, spleen; anywhere besides LN)

EXAM Q
In cutaneous melanomas, it is important to get a histologic report because ___ correlates to malignancy.

mitotic index

In cutaneous melanomas, most melanomas located in _____ areas are benign, but most at the _____ areas are malignant

benign: haired skin, eyelid

malignant: mucocutaneous jxn

List three prognostic factors for oral melanoma

-size: <2 cm has better survival, >2 cm more likely to met
-position: rostral is better
-bony lysis: worse prognosis
-aggressive first treatment intervention: better px