6 Canine Melanoma

1 / 17
what is the tissue origin for melanomas?
Click the card to flip 👆
Terms in this set (17)
Your patient has an oral melanoma. You know how important it is to aspirate regional LNs (submandibular) when staging melanomas because they met there so frequently. You look at the aspirate on a slide and see cells with pigment in them. You decide to send them to the pathologist, because you're not sure if they're melanoma cells or if they're ____
T/F Chemotherapy is crucial to the success of melanoma treatmentFALSE It's a mesenchymal tumor --> very resistant to chemoDescribe the ideal treatment plan for an oral melanomaFor local disease: -SURGERY -radiation For distant mets: -chemo (carboplatin, piroxicam) -immunotherapyWhat is the main problem with trying to use immunotherapy to treat melanomas?tolerance or anergyIn dogs using the Merial Oncept vaccine, median survival time was ~____~1 yr (389 days)The UF melanoma vaccine uses _______ as the antigen it wants the body to target. This is an unusual antigen, because it is not a protein (the typical strong antigens are proteins)gangioside-3, GD3In the UF melanoma vaccine study, they analyzed survival data based on location (oral, foot, cutaneous), grade (low, intermediate, high), and stage (I, II, III, IV). Which category was an independent predictor of survival, i.e. which of these makes a difference in how long they live?GRADEDescribe the grading system for canine melanomas as it was used in the UF Vaccine study -Low -Intermediate -High-Low: 0-3 mitotic figures/10 hpf -Intermediate: 4-12 mitotic figures/10 hpf -High: >12 mitotic figures/10 hpf