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5 Written questions

5 Matching questions

  1. carbapenems
  2. macrolides
  3. antimicrobial agents
  4. antibiotic inactivation
  5. chloramphenicol
  1. a used against gram positive; alternative to penicillin; erythromycin blocks protein synthesis by inhibiting chain elongation (ZPAC-azithromycin)
  2. b used against a variety of bacteria and rickettsiae and fungi; interferes with the peptide bond formation; meningitis, cholera, typhoid fever, rocky mountain spotted fever; can cause aplastic anemia or gray syndrome
  3. c bacteria may evolve the ability to enzymatically inactivate an antibiotic
  4. d chemotherapeutic drugs used to treat infectious disease
  5. e broad spectrum; highly resistant to beta lactamases; last resort for many bacterial infections; primaxin

5 Multiple choice questions

  1. says that antimicrobial agent should harm the the infectious agent but not the host
  2. bacteria evolve changes in drug targets like ribosomes or enzymes involved in replication
  3. attach to bacterial ribosomes blocking translation of RNA into proteins
  4. block DNA synthesis in bacteria; broad spectrum; urinary tract infections; ex. ciprofloxacin, nofloxacin
  5. kills bacteria in the intestines; inhibits cell wall synthesis but drug of last resort because it can cause damage to ears and kidneys; is resisted by enterococcus

5 True/False questions

  1. rifampininterferes with nucleic acid synthesis in RNA synthesis; effective against tb, leprosy, meningitis; causes liver damage; used with Isoniazid and Ethambutol


  2. antibioticsinhibits the peptide crosslinking of carbohydrates between peptidoglycan layers during wall formation


  3. neosporinintestinal infections; broad spectrum; ointments


  4. cephalosporinsbroader spectrum alternative to penicillins; gram positive and gram negative; resistant to many beta lactamases; cefixime


  5. therapeutic doseconcentration of a drug that eliminates pathogens in the host