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5 Written questions

5 Matching questions

  1. penicillinase
  2. oxazolidinones
  3. synthetic drug
  4. alternate metabolic pathway
  5. chemotherapeutic agents
  1. a effective against gram positive bacteria but is a last resort because it produces allergic reactions and is highly toxic to mitochondria
  2. b used to treat infections, diseases, and other disorders such as cancer
  3. c inactivates penicillin by opening the beta lactam ring
  4. d drug synthesized in the pharmaceutical lab; like prontosil and salvarsan
  5. e resistance to sulfonamides may develop if the bacterial enzyme changes or if the bacteria evolves an alternate metabolic pathway

5 Multiple choice questions

  1. kills bacteria in the intestines; inhibits cell wall synthesis but drug of last resort because it can cause damage to ears and kidneys; is resisted by enterococcus
  2. active against aerobic, gram negative rods; narrow spectrum; low toxicity; used for noscomial diseases and bacterial meningitis
  3. used against a variety of bacteria and rickettsiae and fungi; interferes with the peptide bond formation; meningitis, cholera, typhoid fever, rocky mountain spotted fever; can cause aplastic anemia or gray syndrome
  4. derived from a lincosamide; used against penicillin resistant bacteria; typically kills microbiota causing pseudomembranous colitis
  5. bacteria evolve changes in drug targets like ribosomes or enzymes involved in replication

5 True/False questions

  1. macrolidesused against gram positive; alternative to penicillin; erythromycin blocks protein synthesis by inhibiting chain elongation (ZPAC-azithromycin)

          

  2. neosporinintestinal infections; broad spectrum; ointments

          

  3. Alexander Flemingderived from a lincosamide; used against penicillin resistant bacteria; typically kills microbiota causing pseudomembranous colitis

          

  4. gentamicinused in wound tissue

          

  5. toxic doseconcentration of a drug that causes harm to the host