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5 Written questions

5 Matching questions

  1. target modification
  2. toxic dose
  3. vancomycin
  4. cephalosporins
  5. alternate metabolic pathway
  1. a kills bacteria in the intestines; inhibits cell wall synthesis but drug of last resort because it can cause damage to ears and kidneys; is resisted by enterococcus
  2. b concentration of a drug that causes harm to the host
  3. c broader spectrum alternative to penicillins; gram positive and gram negative; resistant to many beta lactamases; cefixime
  4. d resistance to sulfonamides may develop if the bacterial enzyme changes or if the bacteria evolves an alternate metabolic pathway
  5. e bacteria evolve changes in drug targets like ribosomes or enzymes involved in replication

5 Multiple choice questions

  1. intestinal infections; broad spectrum; ointments
  2. used in wound tissue
  3. drug synthesized in the pharmaceutical lab; like prontosil and salvarsan
  4. first modern synthetic antimicrobial agent; Hata and Ehrlich; arshphenamine; used against syphilis
  5. used to treat infections, diseases, and other disorders such as cancer

5 True/False questions

  1. ethambutolinhibits mycolic acid from being incorporated into the cell wall in mycobacteria; narrow spectrum; combined with rifampin and isoniazid

          

  2. antibioticsinhibits the peptide crosslinking of carbohydrates between peptidoglycan layers during wall formation

          

  3. Isoniazidinterferes with mycolic acid in cell wall synthesis of mycobacteria; narrow spectrum; usually combined with rifampin and ethambutol; limited to tuberculosis

          

  4. chloramphenicolused against a variety of bacteria and rickettsiae and fungi; interferes with the peptide bond formation; meningitis, cholera, typhoid fever, rocky mountain spotted fever; can cause aplastic anemia or gray syndrome

          

  5. antimicrobial spectrumchemotherapeutic drugs used to treat infectious disease