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5 Written questions

5 Matching questions

  1. chemotherapeutic agents
  2. polymyxins
  3. antibiotic resistance test
  4. sulfonamides
  5. chemotherapeutic index
  1. a toxic dose divided by therapeutic dose (all per kg body weight)
  2. b increase membrane permeability of gram negative bacteria; topical use
  3. c used to treat infections, diseases, and other disorders such as cancer
  4. d interfere with the DNA synthesis by competing with PABA in making folic acid; eventually kills the bacterial cell
  5. e tube dilution method, agar disk diffusion

5 Multiple choice questions

  1. drugs partly of laboratory origin and partly of microbial origin; improve the natural product; reduce side effects
  2. used against gram negative infections of the urinary tract
  3. bacteria may evolve the ability to prevent drug entry into the cytoplasm or to pump the drug out of the cytoplasm
  4. intestinal infections; broad spectrum; ointments
  5. polypeptide antibiotic; interferes with transport of cell wall precursors through the cell membrane; toxic internally so used topically

5 True/False questions

  1. monobactamsbroad spectrum; highly resistant to beta lactamases; last resort for many bacterial infections; primaxin


  2. therapeutic doseconcentration of a drug that eliminates pathogens in the host


  3. synthetic drugdrug synthesized in the pharmaceutical lab; like prontosil and salvarsan


  4. cephalosporinsbroader spectrum alternative to penicillins; gram positive and gram negative; resistant to many beta lactamases; cefixime


  5. antimicrobial agentsrange of pathogens to which a certain drug will work