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Week 2: AH Streptococcus: Viridans Group
Terms in this set (26)
AT BCIT we are responsible for differentiation viridans from ____________
When can we ignore speciating viridans group? What is the exception?
If a part of normal flora? If it looks more like S. Pneumoniae
S. mitis Group are normal flora of what 4 sites?
oral cavity; GIT; female genital tract; skin
S. mitis group is the primary flora found in what site?
What are the 5 subgroups of the viridans group that we consider. Which two are most important to us?
S. mitis Group; S. anginosus Group; S. salivarius Group; S. mutans group; S. bovis group;
S. anginosus and S. bovis
Which group is the poster child for viridans group?
Why is viridans a misonmer?
b/c some viridans in the group are BH or NH
What Lancfield groups can S. anginosus be? Are they always groupable?
A,C,F or G; no
What is the classic morphology (micro and macro) from viridans (S. anginosus in particular)?
On BAP/CO2 --> AH sm gr raised dry
Will be less trans than strep pneumo
s/ gpc (variable) pr ch pleo (cocci, rods, clubs)
How are we expected to ID viridans at Level 2 (micro and macro)?
AH sm gr raised dry
s/gpc pleo ch
What problem does viridans have with hemolysis as it gets older?
What biochemical tests are used to identify viridans group?
Taxo P (Optochin); Bile Solubility
When is full identification to species group performed for viridans group strep?
when isolated from sterile sites
How is a positive Taxo-P for viridans interpreted?
no zone = resistant --> POS for viridans
What result of Bile Solubility test indicates viridans?
NEG -->Insoluble (Intact colonies)
S. Pneumonia is POS --> soluble
When is the Bile Solubility test performed on viridans?
Only 1) S. pnemmoniae is suggested by zone diameter or 2) if zone is equivocal
When is no further testing of viridans required?
If Taxo-P = resistant with no zone of inhibition and macro/micro appearance is typical of viridans (dry & raised on plate, pleomorphic on smear)
In the right host, what 6 conditions might viridans lead to?
What is SBE? Which strep group causes it?
Sub-acute bacterial endocarditis; viridans group
What % of SBE is caused by viridans group?
In what type of heart valves is SBE caused by viridans more frequent? What are the symptoms?
damaged native heart valves; weight loss, anemia, heart murmer
Strep Pneumonia causes acute bacterial endocarditis due to ________
complications of lumbar pneumonia
Resistance seen in viridans requires which two drugs for combined therapy? Why is this effective?
Penicillin/ampicillin and aminoglycosides. Penicillin breaks down wall so that aminoglycoside can get to ribosomes (aminoglycosides usually a gram neg drug)
What is in the A category of AST for viridans?
Penecillin (Pen G is drug of choice)
How are AST plates of strep viridans incubated?
Same as other strep: BAMH/CO2 20-24hrs
AST of viridan group isolates from CSF or blood involves which 4 drugs? Which two require MIC method?
Penicillin, ampicillin, ceftriaxone, vancomycin; Pen and amp
THIS SET IS OFTEN IN FOLDERS WITH...
Week 1: Group A Strep
Week 1: BH Group C & G Strep
Week 1: Strep Anginosus Group (small colony BH)
Week 1: Group B Strep (S. Agalactiae)
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