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Terms in this set (13)
Result from the influence of an unrelated factor or agent, either natural or artificial
Happen naturally and randomly, arising from replication error and base modifications
occur in any cell except germ cells and are not heritable
Occur in gametes and are inherited
Change a codon resulting in altered amino acid
changes a codon into a stop codon and results in premature termination of translation
Alters a codon but does not result in a change in the amino acid at that position of the protein
Fibrodysplasia Ossificans Progressiva - point mutation in a bone morphogenetic protein type I receptor
Frame shift mutation
Result from insertions or deletions of a base pair. Eg. Muscular dystrophy results from a frame shift mutation in the dystrophy gene on X chromosome.
Eg2. ABO blood system
DNA replication errors
DNA polymerase occasionally insets incorrect nucleotides, generally due to base mispairing
- Lead to point mutations
During replication can lead to small insertions or deletions
Elements that can move within the genome and insert themselves into various positions within the genome, potentially causing mutations
Arise from DNA damage caused by chemicals and radiation
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