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Terms in this set (21)
Is treponema pallidum gram positive or gram negative?
Gram negative rod
What infection does treponema pallidum cause?
What type of organism is treponema pallidum?
Obligate intracellular organism - can't live outside a cell
What technique does treponema pallidum utilize?
Does treponema pallidum contain lipopolysaccharides?
No (there are no endotoxins)
How is Treponema pallidum transmitted?
Usually sexually transmitted
Can treponema pallidum survive outside of host?
No. It is very sensitive to environmental factors.
What 2 categories of disease does treponema pallidum cause?
Acquired syphilis and congenital syphilis
How is acquired syphilis transmitted?
Sexual contact, break in the skin or mucous membrane (usually genitals, or mouth), sharing needles, direct contact with skin lesions
How is congenital syphilis transmitted?
Transmitted during fetal development or birthing process
What are the stages of syphilis?
Primary, secondary, tertiary
What are the symptoms of primary syphilis?
Occurs within 1-3 weeks after someone has been infected with treponema pallidum, development of hard, painless ulcer (chancre) usually around the genitalia, with spontaneous healing - before healing, the ulcer is covered in a fluid that contains a lot of spirochetes!
How long is the asymptomatic period during primary syphilis?
It can last for up to 24 weeks after the chancre heals
What is the most infectious stage of syphilis?
The secondary stage, or dissemination stage
What are the symptoms of Secondary syphilis?
Spirochetemia (spirochetes in the blood) and infects capillaries near the skin - red rash on any part of the body, but especially the palms and soles. Can also cause multi-organ disease: Hepatitis, meningitis, and nephritis
What happens after the secondary skin lesions resolve?
Syphilis goes into a latent period - which can last for years!
What happens during the latent period of syphilis?
The spirochetes are dormant and a person is asymptomatic
What are the symptoms of tertiary syphilis?
Nervous system degradation, heart problems, and tumors known as gummas throughout the body (skin, liver, bones, brain)
What is the best way to diagnose treponema pallidum?
Anti-body tests in the blood
Does treponema pallidum grow in culture?
What shape is Treponema pallidum?
spirochete (corkscrew shaped)
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