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Question

Red blood cells do not perform aerobic respiration, but they do perform glycolysis. Why do all cells need an energy source, and what would happen if glycolysis were blocked in a red blood cell?

Solution

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All cells need an energy source to have enough energy to perform some actions in essential processes (e.g. synthesis of macromolecules, pumping ions across membranes). Red blood cells don’t have mitochondria and they are completely dependent on glycolysis for ATP. Therefore, if the process of glycolysis was blocked in a red blood cell, loss of its membrane potential would occur and that would lead to death.

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