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Question

At first, Donnie’s wife accused her once-active 25-year-old husband of trying to get out of housework by constantly complaining about pain and stiffness in his lower back. But over the next 5 months, the pain and stiffness increased and seemed to be spreading up his vertebral column. The family doctor referred Donnie to a rheumatologist, who diagnosed ankylosing spondylitis (AS). AS, a chronic inflammation of joints at points where ligaments, tendons, and joint capsule insert into bone, causes fibrosis (the development of scar tissue), ossification, and fusion of joints. Combine your knowledge about bone growth, repair, and anatomy from chapters 6 and 7 and joint structure and function from this chapter to identify the category of joints primarily affected by AS, and explain how chronic inflammation of Donnie’s joints led to their fusion.

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Ankylosing spondylitis is a condition affecting the joints and ligaments of the spine. The first sign of AS is usually inflammation of the sacroiliac joints.

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