Question

Describe how the concentration of Ca2+Ca^{2+} in the sarcoplasmic reticulum of a muscle cell changes before, during, and after the cell is excited by a nerve impulse (action potential).

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Answered two weeks ago

Ca2+ ion is the most important for muscle contraction. The inner cell storage of calcium is its endoplasmic reticulum, called sarcoplasmic in muscle cells. While resting, Ca2+ concentration in the sarcoplasm (muscle cell cytoplasm) is low. When the cell receives a nerve impulse and starts depolarizing, the depolarization impulse travels along T tubule (invagination of cell membrane) and reaches sarcoplasmic reticulum. It releases Ca2+ ions and they enable contraction, when its concentration in the sarcoplasm is much greater. After the contraction is over, the sarcoplasmic reticulum pumps the Ca2+ ions back in.

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