Explain how enzymes within synaptic clefts and reuptake of neurotransmitter prevents continuous stimulation of the postsynaptic cell.
Enzyme acetylcholinesterase, released in synaptic and postsynaptic cleft, catalyzes the breakdown of acetylcholine and monoamine oxidase which inactivate epinephrine and norepinephrine after reuptake.
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Once all postsynaptic membrane receptors are taken, a chance of neurotransmitter accumulation and toxicity exists.
For example, acetylcholine accumulation can lead to weakness of muscles and muscular palsy. To prevent that, mechanisms for neurotransmitter degradation and reuptake exist.