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How does heparin help prevent blood clot formation?

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Heparin is a product of the heparin-secreting cells, which are most abundant in the liver, lungs, in the connective tissue surrounding capillaries, and prevents blood clot formation. Heparin inhibits coagulation by inactivating thrombin ( the major clotting protein) and preventing the conversion of fibrinogen to fibrin. Heparin and Coumadin are used as drugs to prevent abnormal clotting.

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