Related questions with answers
How does the archaeal RNA polymerase differ from that in Bacteria? How does the initiation of transcription in the two domains differ? Why do eukaryotic mRNAs have to be "processed" whereas most prokaryotic RNAs do not?
Solution
VerifiedThe archaeal RNA polymerase has 11 to 13 subunits, whereas the bacterial RNA polymerase has only 4 subunits. In other words, the archaeal RNA polymerase is more complex than its bacterial counterpart.
While bacterial transcription is initiated by a sigma factor, archaeal transcription is initiated by TBP (TATA-binding protein) and TFB (archaeal transcription factor B). Once TBP recognizes and binds to the TATA box and TFB recognizes and binds to the B recognition element sequence (BRE), archaeal RNA polymerase can attach and commence transcription.
Unlike most prokaryotic RNAs, eukaryotic mRNAs have to be processed because Eukarya contain genes composed of both coding and noncoding regions. Therefore, processing isolates the coding regions (exons) from the noncoding regions (introns) and generates mature RNAs (RNAs that contain only exons).
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