If the bacteria E. coli synthesize DNA at a rate of 100,000 nucleotides per min and it takes 30 min to replicate the DNA, how many base pairs are in an E. coli chromosome?

Describe the role of DNA helicase, DNA polymerase, and DNA ligase in DNA replication.

Suppose that E. coli synthesizes DNA at a rate of 100,000 nucleotides per minute and takes 40 minutes to replicate its chromosome. (a) How many base pairs are present in the entire E. coli chromosome? (b) What is the physical length of the chromosome in its helical configuration-that is, what is the circumference of the chromosome if it were opened into a circle?

Analyze how the activity of DNA polymerase is consistent with Watson and Crick's model of semiconservative replication.

Describe two characteristics that DNA needs to fulfill its role as a genetic material.

Describe the function of each of the following in protein synthesis: rRNA, mRNA, and tRNA.

An outbreak of E. coli infections in August of 2010 occurred in three Washington state day care centers. There were eight confirmed and six suspected cases of E. coli, with over 70 children awaiting test results. Outbreaks of E. coli infections for 2009 are reported to be less than 1 per 100,000, down from 2.5 per 100,000 reported earlier. Using the rate of 1 per 100,000, find the following probabilities. a. What is the probability that at most two outbreaks per 100,000 are reported across the United States this year? b. What is the probability that more than three outbreaks per 100,000 are reported across the United States this year?

At what age did most adult smokers begin their habit?

Summarize the experiments of Griffith and Avery that indicated that DNA is the genetic material.

During DNA replication, the leading strand is synthesized continuously, whereas the lagging strand is synthesized as Okazaki fragments. Why is this so?

A. DNA synthesis can take place only in the 5' to 3' direction.

B. There are thousands of origins of replication on the lagging strand but only one on the leading strand.

C. DNA polymerases can bind to only one strand at a time.

What is the importance of regulating gene expression? ___________________________

Hypothesize why DNA replication has such accuracy.

Describe the data used by Watson and Crick to determine the structure of DNA.

Draw and label a segment of DNA showing its helix and complementary base pairing.