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Question

What is the effect of a nonsense mutation in a gene?

A) It has no effect on the amino acid sequence of the encoded protein.
B) It prevents introns from being excised.
C) It alters the reading frame of the mRNA.
D) It introduces a premature stop codon into the mRNA.
E) It changes an amino acid in the encoded protein.

Solution

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Answered 11 months ago
Answered 11 months ago
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A nonsense variation is a certain type of substitution. The changed DNA sequence produces a stop signal that tells the cell to cease producing proteins prematurely. This is a typical type of mutation that occurs in both humans and other animals and results in the expression of a shortened or useless protein.

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