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Question

When researchers compared gene expression in normal breast cells and cells from breast cancers, they found that the genes showing the most significant differences in expression encoded signal receptors. Explain why this result is not surprising.

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There are receptors on cell membranes that receive certain signals from the environment. Environmental signals cause a cascade reaction in the cell and a cellular response. The cellular response may be the transcription of target genes or the opening of transmembrane channels for specific molecules.

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