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Which factors influence the rate of glomerular filtration?

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Glomerular filtration rate is the amount of fluid that is filtered in one minute. Normal rate is about 125 ml/min. This factor is the best in revealing the level of kidney function. Factors that affect the glomerular filtration are glomerular hydrostatic pressure, glomerular colloidal osmotic pressure, and the hydrostatic pressure in the Bowman's capsule. Glomerular hydrostatic pressure in the glomerulus is about 60 mmHg, which is higher than in other capillaries in the body (20-25 mmHg). In the Bowman's capsule, it is about 18 mmHg which tells us that the water will go from the glomerulus to the capsular space. Colloid osmotic pressure is around 32 mm Hg.

Net filtration pressure = Glomerular hydrostatic pressure - Plasma colloid osmotic pressure - Capsular hydrostatic pressure

Glomerular filtration rate is directly proportional to the net filtration pressure. Various factors that affect glomerular hydrostatic pressure, plasma colloid pressure, or capsular hydrostatic pressure indirectly affect the glomerular filtration rate.

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