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The number of codons exceeds the number of amino acids, meaning that few amino acids can be encoded by more than one codon. The one-to-one correspondence between amino acid and codon lacks here, making genetic code .
As already mentioned, one amino acid can be encoded by more than one codon. In cases like this, there are different tRNAs (anticodons) for the same amino acid.
However, it is also possible that one tRNA molecule recognizes more than one codon. That is called and can happen when the standard base pairs are formed only at the first two positions of the codon. At the third position, improper pairing is tolerated (e.g., one anticodon of lysyl tRNA in can base-pair with AAA or AAG codons). The fidelity of the genetic code is affected, as the third base of a codon is not accurately recognized.
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