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Pelvic inflammatory Disease

Terms in this set (9)

What is PID?
A clinical syndrome resulting from cervical microorganisms ascending to the endometrium, fallopian tubes, and contiguous structures
What are the risk factors for PID?
Being a teenage girl, having multiple sexual partners, using intrauterine devices, and having prior PID
What are the usual pathogens in PID?
Usually polymicrobic agents: N. gonorrhea, C. trachomatis, and mixed aerobic and anaerobic bacteria
What is the classic triad of symptoms and signs in PID?
Pelvic pain, increased vaginal discharge, and fever (found in only 20% of women). Asymptomatic PID may also occur.
What are the sequelae of PID?
Infertility, ectopic pregnancy, chronic pelvic pain, and recurrent episodes of PID
How is the diagnosis of PID made?
Clinical findings suggested by direct abdominal tenderness, cervical motion tenderness, and adnexal tenderness plus 1 or more of the following: temperature > 38°C, WBC count > 10,000/mm3, or pelvic abscess found by manual examination or ultrasonography
What is the differential diagnosis for PID?
Ectopic pregnancy, acute appendicitis, ruptured ovarian cyst, endometriosis, and ovarian torsion
What is the treatment for PID for Outpatient therapy?
1. Ceftriaxone 250 mg IM single dose plus doxycycline 100 mg twice a day for 14 days, with or without metronidazole

2. Cefoxitin 2 g IM single dose and Probenecid 1 g orally given concurrently, plus doxycycline 100 mg twice a day for 14 days, with or without metronidazole
Inpatient therapy?
1. Cefoxitin (2 g IV every 6 hours) or cefotetan (2 g IV every 12 hours) plus doxycycline (100 mg IV every 12 hours). Cefoxitin or cefotetan should be continued for at least 48 hours after significant clinical improvement is noted.

2. Clindamycin 900 mg IV every 8 hours plus gentamicin 2 mg/kg loading dose, 1.5 mg/kg every 8 hours
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