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Study sets matching "1 skeletal muscle relaxants"

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Study sets matching "1 skeletal muscle relaxants"

10 terms
skeletal muscle relaxants 1
what are the 2 categories of skeletal…
what are the two types of neuromuscula…
when Ach binds to the _ receptors on t…
How are the postjunctional receptors d…
neuromuscular blocking agents... skeletal muscle spasmolytic drugs
depolarizing... non-depolarizing... To provide skeletal muscle rel…
nicotinic cholinergic (Nm); potassium, sodium; contract; AchE…
They are glycoproteins with 5 subunits- 2 alpha, and 1 each o…
what are the 2 categories of skeletal…
neuromuscular blocking agents... skeletal muscle spasmolytic drugs
what are the two types of neuromuscula…
depolarizing... non-depolarizing... To provide skeletal muscle rel…
17 terms
Skeletal Muscle Relaxants (1/22)
What are the 2 broad types of muscle r…
What is the classification of skeletal…
What is the structure of the nicotinic…
What is a curare?
Neuromuscular blockers - completely paralyze skeletal muscle…
Peripherally acting drugs:... - Neuromuscular blocking drugs... - D…
2 a subunits... 1 y subunit... 1 B subunit... 1 d subunit - (switches…
alkaloid found in south american plants - most important one…
What are the 2 broad types of muscle r…
Neuromuscular blockers - completely paralyze skeletal muscle…
What is the classification of skeletal…
Peripherally acting drugs:... - Neuromuscular blocking drugs... - D…
14 terms
1.10 - Skeletal Muscle Relaxants
Atracurium
Tubocurarine
Pancuronium
Rocuronium
Nondepolarizing - Neuromuscular Blocker ... Elimination: Spontan…
Nondepolarizing - Neuromuscular Blocker... Elimination: Kidney (…
Nondepolarizing - Neuromuscular Blocker... Elimination: Kidney (…
Nondepolarizing - Neuromuscular Blocker... Elimination: Liver (7…
Atracurium
Nondepolarizing - Neuromuscular Blocker ... Elimination: Spontan…
Tubocurarine
Nondepolarizing - Neuromuscular Blocker... Elimination: Kidney (…
48 terms
Exam 1- Skeletal Muscle Relaxants
Skeletal Muscle Relaxants act on what…
Goal is to...
What is the most frequent route of adm…
For severe spasms what drug route is g…
-spinal cord... -neuromuscluar junction... -muscle cell
normalize muscle excitability without a profound disruption o…
oral
-IM... -IV
Skeletal Muscle Relaxants act on what…
-spinal cord... -neuromuscluar junction... -muscle cell
Goal is to...
normalize muscle excitability without a profound disruption o…
19 terms
Skeletal muscle relaxants/spasmolytics
Which one of the above produces muscle…
The effects of this drug can be shorte…
A 47-year-old man has a routine surgic…
A 34-year-old woman with multiple scle…
E. succinylcholine... Structurally, succinylcholine is two acety…
D. rocuronium... Rocuronium and the other ...curiums (atra, miv…
C. Dantrolene, a potent specific inhibitor of skeletal muscle…
A. baclofen... baclofen reduces muscle spasm at the spinal leve…
Which one of the above produces muscle…
E. succinylcholine... Structurally, succinylcholine is two acety…
The effects of this drug can be shorte…
D. rocuronium... Rocuronium and the other ...curiums (atra, miv…
60 terms
SUMMARY Skeletal Muscle Relaxants
Succinylcholine
Succinylcholine
Succinylcholine
Succinylcholine
Agonist at nicotinic acetylcholine (ACh) receptors, especiall…
Initial depolarization causes transient contractions, followe…
Placement of endotracheal tube at start of anesthetic procedu…
Rapid metabolism by plasma cholinesterase • normal duration,…
Succinylcholine
Agonist at nicotinic acetylcholine (ACh) receptors, especiall…
Succinylcholine
Initial depolarization causes transient contractions, followe…
66 terms
Skeletal Muscle Relaxants Lecture
What is the active compound that cause…
d - tubocurarine
Two types of membrane potentials
Pharmacological Classifications
d - tubocurarine
Produce skeletal muscle paralysis ... Prototype of non depolari…
Endplate potential ... Action potential
Nondepolarizing... Depolarizing
What is the active compound that cause…
d - tubocurarine
d - tubocurarine
Produce skeletal muscle paralysis ... Prototype of non depolari…
33 terms
Skeletal Muscle Relaxants
Nicotinic Blockers
Skeletal muscle relaxants
Skeletal muscle relaxants: Non-depolar…
Skeletal muscle relaxants: Depolarizin…
PERIPHERAL actiong... Two Types:... *Nicotinic (Muscle) (NM) rece…
Act on nicotinic receptors present at the neuromuscular junct…
CURONIUM (Curare... derivatives)... Long acting: d-tubocurarine,…
Succinylcholine (Suxamethonium)
Nicotinic Blockers
PERIPHERAL actiong... Two Types:... *Nicotinic (Muscle) (NM) rece…
Skeletal muscle relaxants
Act on nicotinic receptors present at the neuromuscular junct…
123 terms
Anesthetics and Skeletal Muscle Relaxants
Name the ester-type local anesthetics…
Name the amide-type local anesthetics…
Which local anesthetics have topical a…
Which local anesthetics have parentera…
Benzocaine, Cocaine, Chloroprocaine, Procaine, Tetracaine
Articaine, Bupivacaine, Lidocaine, Mepivacaine, Priolocaine,…
Bezocaine, Cocaine, Tetracaine, Lidocaine
All EXCEPT benzocaine and cocaine
Name the ester-type local anesthetics…
Benzocaine, Cocaine, Chloroprocaine, Procaine, Tetracaine
Name the amide-type local anesthetics…
Articaine, Bupivacaine, Lidocaine, Mepivacaine, Priolocaine,…
19 terms
Skeletal muscle relaxants/spasmolytics
Which one of the above produces muscle…
The effects of this drug can be shorte…
A 47-year-old man has a routine surgic…
A 34-year-old woman with multiple scle…
E. succinylcholine... Structurally, succinylcholine is two acety…
D. rocuronium... Rocuronium and the other ...curiums (atra, miv…
C. Dantrolene, a potent specific inhibitor of skeletal muscle…
A. baclofen... baclofen reduces muscle spasm at the spinal leve…
Which one of the above produces muscle…
E. succinylcholine... Structurally, succinylcholine is two acety…
The effects of this drug can be shorte…
D. rocuronium... Rocuronium and the other ...curiums (atra, miv…
27 terms
Pharmacology Test 1 - Skeletal Muscle Relaxants
Peripheral Muscle Relaxants
Centrally-Acting Muscle Relaxants
2 classes of Neuromuscular relaxants
non-depolarizing blockers
-inhibit muscle contractions by interfering with the contract…
-block conduction within the spinal cord... -for pain
1. non-depolarizing blockers... 2. depolarizing blockers
competitive antagonists
Peripheral Muscle Relaxants
-inhibit muscle contractions by interfering with the contract…
Centrally-Acting Muscle Relaxants
-block conduction within the spinal cord... -for pain
28 terms
Skeletal Muscle Relaxants (week 3)
Contraction of skeletal muscle (big pi…
motor unit (pic)
steps and pic
skeletal muscle contraction video clip:
Somatic neurons connect with skeletal muscle fibers at the ne…
http://www.bing.com/videos/search?q=neuromuscular+jucntion+de…
Contraction of skeletal muscle (big pi…
Somatic neurons connect with skeletal muscle fibers at the ne…
motor unit (pic)
26 terms
Skeletal Muscle Relaxants
Spasticity
Spasticity symptoms
Clonus
Mechanism
A disordered sensory motor control resulting from upper motor…
Hypertonicity (increased muscle tone) ... Exaggerated deep tendo…
series of rapid muscle contractions
hyper excitability of alpha motor neurons in the spinal cord
Spasticity
A disordered sensory motor control resulting from upper motor…
Spasticity symptoms
Hypertonicity (increased muscle tone) ... Exaggerated deep tendo…
40 terms
Block 3 Pharmacology 1: Skeletal Muscle Relaxants
What are the two classes of spasmolyti…
What are antispastic drugs used for?
What are antispasmodic drugs used for?
What are the acute-use antispasmodics?
Antispastics and antispasmodics.
Long-term treatment of spasticity in CNS disorders.
Prevention and relief of use-related minor muscle spasms.
Chlorzoxazone, cyclobenaprine, methocarbamol, crasioprodol an…
What are the two classes of spasmolyti…
Antispastics and antispasmodics.
What are antispastic drugs used for?
Long-term treatment of spasticity in CNS disorders.
9 terms
Skeletal Muscle Relaxants
Baclofen
Carisoprodol
Cyclobenzaprine
Methocarbamol
Gablofen, Lioresal
Soma
Amrix, Fexmid, Flexeril
Robaxin
Baclofen
Gablofen, Lioresal
Carisoprodol
Soma
9 terms
Skeletal muscle relaxants
Diazepam (skeletal muscle relaxants)
Cylcobenzaprine (skeletal muscle relax…
Methocrbamol (skeletal muscle relaxants)
Baclofen (skeletal muscle relaxants)
Valium
Flexeril
Robaxin
Lioresal
Diazepam (skeletal muscle relaxants)
Valium
Cylcobenzaprine (skeletal muscle relax…
Flexeril
21 terms
6-1 Skeletal Muscle Relaxants and Neuromuscular Blockers
Muscle relaxants are use to?
Most muscle relaxants act on the?
Spasticity?
Muscle Relaxants: therapeutic indicati…
-diminish skeletal muscle tone for:... muscle relaxation (musc…
Central nervous system.... They are not selective for muscle r…
Increased muscle tone.... Excessive muscle tone (due to augmente…
-Muscle spasm due to:... Multiple sclerosis ... Cerebral palsy... Spin…
Muscle relaxants are use to?
-diminish skeletal muscle tone for:... muscle relaxation (musc…
Most muscle relaxants act on the?
Central nervous system.... They are not selective for muscle r…
Skeletal Muscle Relaxants
Strain
Sprains
Skeletal Muscle Spindle
Type I and II sensory afferents
Twist or over-stretching, pull and/or tear of a muscle or ten…
Stretch or/and tear of a ligament (connects bone to bone) tha…
-Responsible for controlling muscle tone
-Within the spindle center they respond to rate and degree of…
Strain
Twist or over-stretching, pull and/or tear of a muscle or ten…
Sprains
Stretch or/and tear of a ligament (connects bone to bone) tha…
15 terms
Pharmacology- Skeletal muscle relaxants
d-tubocurarine
Succinylcholine
Pancuronium
Pipecuronium
Due to its prominent histamine releasing, ganglionic blocking…
Despite its actions similar to d-TC and K+ release causing hy…
Synthetic compound, 5 times more potent than d-TC provides go…
Slow onset & long duration of action, steroidal in nature... Rec…
d-tubocurarine
Due to its prominent histamine releasing, ganglionic blocking…
Succinylcholine
Despite its actions similar to d-TC and K+ release causing hy…
33 terms
Skeletal Muscle Relaxants
Nicotinic Blockers
Skeletal muscle relaxants
Skeletal muscle relaxants: Non-depolar…
Skeletal muscle relaxants: Depolarizin…
PERIPHERAL actiong... Two Types:... *Nicotinic (Muscle) (NM) rece…
Act on nicotinic receptors present at the neuromuscular junct…
CURONIUM (Curare... derivatives)... Long acting: d-tubocurarine,…
Succinylcholine (Suxamethonium)
Nicotinic Blockers
PERIPHERAL actiong... Two Types:... *Nicotinic (Muscle) (NM) rece…
Skeletal muscle relaxants
Act on nicotinic receptors present at the neuromuscular junct…
12 terms
skeletal muscle relaxants
diazepam
baclofen
cyclobenzaprine
dantrolene
benzodiazepine... positive allosteric modulator that acts at GAB…
MOA: agonist at GABA B receptor (Gi/Go coupled)... acts on GABA…
used to treat local muscle spasm... tricyclic structure... MOA: ant…
MOA: binds to RyR channel in SR and inhibits opening of chann…
diazepam
benzodiazepine... positive allosteric modulator that acts at GAB…
baclofen
MOA: agonist at GABA B receptor (Gi/Go coupled)... acts on GABA…
16 terms
Skeletal Muscle Relaxants (Final)
sprain vs. strain
sprain vs. strain curtailed
symptoms of a sprain
symptoms of a strain
sprain - stretch and/or tear of a ligament, caused by direc…
sprains - ligaments... strains - muscle/tendon, associated with…
pain, bruising, inflammation, severe pain and joint loosening…
muscle spasms, muscle weakness, pain, swelling, inflammation,…
sprain vs. strain
sprain - stretch and/or tear of a ligament, caused by direc…
sprain vs. strain curtailed
sprains - ligaments... strains - muscle/tendon, associated with…
8 terms
Skeletal Muscle Relaxants Drugs
Flexeril... (Brand Name)
Norflex... (Brand Name)
Parafon Forte... (Brand Name)
Robaxin... (Brand Name)
Cyclobenzaprine
Orphenadrine
Chlorzoxazone
Methocarbamol
Flexeril... (Brand Name)
Cyclobenzaprine
Norflex... (Brand Name)
Orphenadrine
36 terms
Skeletal Muscle Relaxants
Atracurium (benzylisoquinolines)
Cisatracurium (benzylisoquinolines)
Pancuronium (aminosteroid)
Vecuronium (aminosteroid)
non-depolarizing (compatative) blocker... ADME: ... -Poor GI need I…
non-depolarizing (compatative) blocker... -Poor GI need IV, ... -Pl…
non-depolarizing (compatative) blocker... - Long acting (1-2hrs)…
non-depolarizing (compatative) blocker... AE's - Caution with li…
Atracurium (benzylisoquinolines)
non-depolarizing (compatative) blocker... ADME: ... -Poor GI need I…
Cisatracurium (benzylisoquinolines)
non-depolarizing (compatative) blocker... -Poor GI need IV, ... -Pl…
34 terms
Skeletal Muscle Relaxants (FINAL)
a twist, over-stretching, pull and/or…
a stretch and/or tear of a LIGAMENT th…
What are muscle relaxants used for
__responsible for controlling muscle t…
strains
sprains
-sprains... - strains... - lower back pain/injury
A) skeletal muscle spindles
a twist, over-stretching, pull and/or…
strains
a stretch and/or tear of a LIGAMENT th…
sprains
21 terms
Skeletal Muscle Relaxants
What do NMB block at low/high doses re…
Do most clinical NMB work pre-synaptic…
What is the name of the only depolariz…
Non-depolarizing NMBs are competitive/…
low: transmission of neurological signal at NMJ... high: ion cha…
post-synaptically
suxamethonium
competitive antagonists... nicotinic... ACh
What do NMB block at low/high doses re…
low: transmission of neurological signal at NMJ... high: ion cha…
Do most clinical NMB work pre-synaptic…
post-synaptically
49 terms
Skeletal Muscle Relaxants
Enzyme that breaks down Ach at the NJM?
What are the 2 classes of NMJ blockers?
What is the function of nondepolarizin…
Example of a nondepolarizing NMJ blocker
Acetlycholinesterase (AchE)
Nondepolarizing and Depolarizing
Nicotinic receptor competitive anatagonists
Tubocurare
Enzyme that breaks down Ach at the NJM?
Acetlycholinesterase (AchE)
What are the 2 classes of NMJ blockers?
Nondepolarizing and Depolarizing
62 terms
Skeletal Muscle Relaxants
What are skeletal muscle relaxants use…
What is a sprain?
Symptoms of a sprain?
What is a strain?
Strains... Lower back injury/ pain
A stretch/ and or tear of a ligament that is caused by a dire…
Pain ... bruising... inflammation... - severe pain and joint loosening…
A twist, over stretching, pull and or tear of the muscle or t…
What are skeletal muscle relaxants use…
Strains... Lower back injury/ pain
What is a sprain?
A stretch/ and or tear of a ligament that is caused by a dire…
19 terms
Pharmacology (Skeletal Muscle Relaxants)
3 Types of muscle groups
Voluntary movement of skeletal muscles
Depolorization
Skeletal muscle relaxants
1. Cardiac muscle (heart) = involuntary... -PANS ... -SANS... 2.Smooth…
-Skeletal muscle movement is controlled by the impulses that…
-When ACH binds to the skeletal muscle receptor (nicotinic-M)…
***Relaxant drugs block skeletal muscle contraction by interf…
3 Types of muscle groups
1. Cardiac muscle (heart) = involuntary... -PANS ... -SANS... 2.Smooth…
Voluntary movement of skeletal muscles
-Skeletal muscle movement is controlled by the impulses that…
18 terms
Pharmacology Skeletal Muscle Relaxants
Overall Physiologic Effect of Muscle R…
Spasm
Spasticity
Causes of Spasms
decrease muscle spasm or spasticity for certain neurologic an…
cramp which is a sudden involuntary, painful muscle contracti…
involves increased muscle tone or contraction and stiff, awkw…
Musculoskeletal trauma/injury... Irritant... Inflammation (sprains,…
Overall Physiologic Effect of Muscle R…
decrease muscle spasm or spasticity for certain neurologic an…
Spasm
cramp which is a sudden involuntary, painful muscle contracti…
27 terms
Pharm - Skeletal Muscle Relaxants
Succinylcholine
Adverse effects of succinylcholine
Tubocurarine, Atracurium, Cisatracuriu…
Adverse effects of benzylisoquinolines
-The only depolarizing blocker... -Two acetylcholine molecules l…
-Activates sympathetic and parasympathetic muscarinic recepto…
-Benzylisoquinolines... -Non depolarizing blockers --> competiti…
May cause hypotension due to histamine release
Succinylcholine
-The only depolarizing blocker... -Two acetylcholine molecules l…
Adverse effects of succinylcholine
-Activates sympathetic and parasympathetic muscarinic recepto…
19 terms
Skeletal muscle relaxants/spasmolytics
Which one of the above produces muscle…
The effects of this drug can be shorte…
A 47-year-old man has a routine surgic…
A 34-year-old woman with multiple scle…
E. succinylcholine... Structurally, succinylcholine is two acety…
D. rocuronium... Rocuronium and the other ...curiums (atra, miv…
C. Dantrolene, a potent specific inhibitor of skeletal muscle…
A. baclofen... baclofen reduces muscle spasm at the spinal leve…
Which one of the above produces muscle…
E. succinylcholine... Structurally, succinylcholine is two acety…
The effects of this drug can be shorte…
D. rocuronium... Rocuronium and the other ...curiums (atra, miv…
9 terms
CNS skeletal muscle relaxants
Name: Methocarbomal... Mechanism: CNS Ske…
Name: Carisoprodol... Mechanism: CNS Skel…
Name: Metaxalone... Mechanism: CNS Skelet…
Name: Baclofen... Mechanism: CNS Skeletal…
Name: Methocarbomal... Mechanism: CNS Ske…
Name: Carisoprodol... Mechanism: CNS Skel…
8 terms
Skeletal Muscle Relaxants Drugs
(Valium)
(Flexeril)
(Robaxin)
(Parafon Forte)
Diazepam
Cyclobenzaprine
Methocarbamol
Chlorzoxazone
(Valium)
Diazepam
(Flexeril)
Cyclobenzaprine
14 terms
Skeletal Muscle Relaxants
Where do neuromuscular blocking agents…
What are skeletal muscle relaxants use…
How do NON-depolarizing neuromuscular…
How does a Depolarizing neuromuscular…
neuromuscular junction: blocking nicotinic cholinergic recept…
-surgical procedures... -tracheal intubation... -seizures
-curari
-Succinylcholine
Where do neuromuscular blocking agents…
neuromuscular junction: blocking nicotinic cholinergic recept…
What are skeletal muscle relaxants use…
-surgical procedures... -tracheal intubation... -seizures
57 terms
Skeletal Muscle Relaxants and Spasmolytics
which receptors are the focus of skele…
what do all neuro-musclular (NM) block…
basic structure of depolarizing NM Blo…
basic structure of non depolarizing NM…
receptor #5... release Ach onto Nicotinic receptors located on…
show structural resemblance to Ach... highly polar, lipid solub…
2 Ach linked - acts to activate Nicotinic receptors... and Musc…
Ach moiety in bulky, rigid ring structure - ... The molecular n…
which receptors are the focus of skele…
receptor #5... release Ach onto Nicotinic receptors located on…
what do all neuro-musclular (NM) block…
show structural resemblance to Ach... highly polar, lipid solub…
19 terms
Skeletal muscle relaxants/spasmolytics
Which one of the above produces muscle…
The effects of this drug can be shorte…
A 47-year-old man has a routine surgic…
A 34-year-old woman with multiple scle…
E. succinylcholine... Structurally, succinylcholine is two acety…
D. rocuronium... Rocuronium and the other ...curiums (atra, miv…
C. Dantrolene, a potent specific inhibitor of skeletal muscle…
A. baclofen... baclofen reduces muscle spasm at the spinal leve…
Which one of the above produces muscle…
E. succinylcholine... Structurally, succinylcholine is two acety…
The effects of this drug can be shorte…
D. rocuronium... Rocuronium and the other ...curiums (atra, miv…
12 terms
Skeletal Muscle Relaxants
Skeletal muscle relaxants: chronic use…
Skeletal muscle relaxants: chronic use…
Skeletal muscle relaxant for acute use
Spasmolytic drugs
Baclofen... Cyclobenzaprine... Diazepam... Tizanidine
Dantrolene... Botulinum toxin
Cyclobenzaprine
*most act in CNS... *reduce abnormally elevated tone caused by n…
Skeletal muscle relaxants: chronic use…
Baclofen... Cyclobenzaprine... Diazepam... Tizanidine
Skeletal muscle relaxants: chronic use…
Dantrolene... Botulinum toxin
9 terms
Skeletal Muscle Relaxants
Structurally related to acetylcholine,…
These drugs strongly potentiate and pr…
These prevent the action of Ach at the…
Agent with long duration of action and…
Neuromuscular blocking drugs
Inhaled anesthetics, especially isoflurane, aminoglycosides,…
Nondepolarizing type antagonists
Tubocurarine
Structurally related to acetylcholine,…
Neuromuscular blocking drugs
These drugs strongly potentiate and pr…
Inhaled anesthetics, especially isoflurane, aminoglycosides,…
42 terms
Skeletal Muscle Relaxants
Main use of Skeletal Muscle relaxants
all neurons exiting the spinal column…
Are nicotinic receptors at the neuromu…
All NMJ relaxants show structural rese…
*Skeletal muscle paralysis during surgery, prolonged ventilat…
cholinergic—neurons that synthesize and release acetylcholine…
no -- they have different subunit compositions of the post-sy…
acetylcholine... - Depolarizing: 2 Ach linked... - Nondepolarizing…
Main use of Skeletal Muscle relaxants
*Skeletal muscle paralysis during surgery, prolonged ventilat…
all neurons exiting the spinal column…
cholinergic—neurons that synthesize and release acetylcholine…
32 terms
skeletal muscle relaxants, spasmolytics
Atracurium
Cisatracurium
Rocuronium
Mivacurim
Spontaneous elimination, so great for multi organ failure pat…
Spontaneous elimination, so great for multi organ failure pat…
Shortest onset (1-2 min), so great for intubations for people…
Has the shortest duration at around 12 min.
Atracurium
Spontaneous elimination, so great for multi organ failure pat…
Cisatracurium
Spontaneous elimination, so great for multi organ failure pat…
32 terms
Skeletal Muscle Relaxants (FINAL)
__a twist, over-stretching, pull and/o…
__ a stretch and/or tear of a LIGAMENT…
__responsible for controlling muscle t…
___ responds to rate and degree of str…
strains
sprains
A) skeletal muscle spindles
B) Type I and II sensory afferents,
__a twist, over-stretching, pull and/o…
strains
__ a stretch and/or tear of a LIGAMENT…
sprains
14 terms
Pharmacology - Skeletal muscle relaxants
Neuromuscular blockers
spasmolytic agents
Non-depolarizing relaxing drugs MOA
AEs of non- depolarizing
- interfere with transmission at the neuromuscular endplate (…
- used to treat conditions of excess skeletal muscle tone... - c…
tubocurarine... - competitive block of Ach... - highly polar... inacti…
- hypotension (histamine)... - tubocurarine, pancuronium
Neuromuscular blockers
- interfere with transmission at the neuromuscular endplate (…
spasmolytic agents
- used to treat conditions of excess skeletal muscle tone... - c…
19 terms
Skeletal muscle relaxants/spasmolytics
Which one of the above produces muscle…
The effects of this drug can be shorte…
A 47-year-old man has a routine surgic…
A 34-year-old woman with multiple scle…
E. succinylcholine... Structurally, succinylcholine is two acety…
D. rocuronium... Rocuronium and the other ...curiums (atra, miv…
C. Dantrolene, a potent specific inhibitor of skeletal muscle…
A. baclofen... baclofen reduces muscle spasm at the spinal leve…
Which one of the above produces muscle…
E. succinylcholine... Structurally, succinylcholine is two acety…
The effects of this drug can be shorte…
D. rocuronium... Rocuronium and the other ...curiums (atra, miv…
19 terms
Skeletal muscle relaxants/spasmolytics
Which one of the above produces muscle…
The effects of this drug can be shorte…
A 47-year-old man has a routine surgic…
A 34-year-old woman with multiple scle…
E. succinylcholine... Structurally, succinylcholine is two acety…
D. rocuronium... Rocuronium and the other ...curiums (atra, miv…
C. Dantrolene, a potent specific inhibitor of skeletal muscle…
A. baclofen... baclofen reduces muscle spasm at the spinal leve…
Which one of the above produces muscle…
E. succinylcholine... Structurally, succinylcholine is two acety…
The effects of this drug can be shorte…
D. rocuronium... Rocuronium and the other ...curiums (atra, miv…
35 terms
Skeletal Muscle Relaxants
Non depolarizing blockers/Competitive…
Non depolarizing blockers... second gener…
Depolarizing blockers... Is this drug sh…
What is the class effect of ALL Nondep…
Tubocurarine (Long acting)... Mivacruim (not metab/cleared by ki…
second generation... Cisatracuium (doesn't release histamine + i…
Succinylcholine... Short acting... Doesn't get metabolized by Ach…
Allows for Muscle relaxation and now don't need higher doses…
Non depolarizing blockers/Competitive…
Tubocurarine (Long acting)... Mivacruim (not metab/cleared by ki…
Non depolarizing blockers... second gener…
second generation... Cisatracuium (doesn't release histamine + i…
22 terms
Pharmacology- skeletal muscle relaxants
Spacicity
Treatment for spacicity involves reduc…
Centrally acting agents (muscle relaxe…
Baclofen (lioresal) ... MOA
Characterized by an increase in tonic stretch reflexes and fl…
Reduce the activity of the Ia affarent fibers that excite the…
Baclofen (lioresal) ... Carisoprodol (soma) ... Cyclobenzaprine (fl…
GABA agonist that interferes with the release of excitatory t…
Spacicity
Characterized by an increase in tonic stretch reflexes and fl…
Treatment for spacicity involves reduc…
Reduce the activity of the Ia affarent fibers that excite the…
8 terms
PHARM skeletal muscle relaxants
_____________, also called curare, is…
_________________, AKA succinylcholine…
__________ acting muscle relaxants dia…
Depolarizing muscle relaxants result i…
tubocurarine, peripherally, non-depolarizing, competitive
suxamethonium, peripherally, depolarizing
Centrally, GABAa, GABAb, orally
excitation, flaccid paralysis, phase 1 block
_____________, also called curare, is…
tubocurarine, peripherally, non-depolarizing, competitive
_________________, AKA succinylcholine…
suxamethonium, peripherally, depolarizing
24 terms
Pharmacology: Skeletal Muscle Relaxants
Neuromuscular Blocking Agents
Atracurium
Cisatracurium
Pancuronium
-curium
Neuromuscular Blocking Agents
Neuromuscular Blocking Agents
Neuromuscular Blocking Agents
Neuromuscular Blocking Agents
-curium
Atracurium
Neuromuscular Blocking Agents
35 terms
ADD LOTS OF NOTES 1-Skeletal Muscle Relaxants
slide 2
spasticity
pictures slides 4-6
muscle spasms due to
...
-increased muscle stiffness... -excessive muscle tone... (due to a…
...
MS... Cerebral palsy ... Spinal cord injury... Tetanus contractions ... S…
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spasticity
-increased muscle stiffness... -excessive muscle tone... (due to a…
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