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Study sets matching "3 molecular cells biology sec"

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Study sets matching "3 molecular cells biology sec"

22 terms
Molecular Cell Biology 3
seal
clamp
translocate
proximal
to close/fasten something tightly
to hold or fasten something very tightly so that it does not…
to move or transfer from one place to another; cause to chang…
near the point of attachment
seal
to close/fasten something tightly
clamp
to hold or fasten something very tightly so that it does not…
12 terms
Cell & Molecular Biology #3
activation energy
enzyme
substrate
product
the energy that must be acquired by a molecule to undergo a c…
a protein that catalyzes a specific chemical reaction
a molecule on which an enzyme acts
...
activation energy
the energy that must be acquired by a molecule to undergo a c…
enzyme
a protein that catalyzes a specific chemical reaction
20 terms
Molecular Cell Biology 3
1. ... Misfolding of polypeptides is a se…
2. ... Hydrophobic interactions make impo…
3. ... To determine the isoelectric point…
4. ... A naturally occurring hindrance to…
D
E
B
D
1. ... Misfolding of polypeptides is a se…
D
2. ... Hydrophobic interactions make impo…
E
22 terms
Molecular Cell Biology 3
ligand
intracellular receptors
cell surface receptors
endocrine signaling
attach to membrane receptor and trigger changes inside the ce…
hormone secreted & released; diffuses across cell membrane an…
ligands bind to membrane receptor sites and create a change w…
hypothalamus release hormones into blood stream to distant ta…
ligand
attach to membrane receptor and trigger changes inside the ce…
intracellular receptors
hormone secreted & released; diffuses across cell membrane an…
85 terms
Cell & Molecular Biology 3
types of proteins
condensation
left and right
none
enzymes, structural (alpha-keratin), transport (hemoglobin),…
peptide bond formation is a ____ reaction
the amino terminus (N-terminus) is on the ___ side, carboxyl…
how much rotation is there around the backbone axis of a poly…
types of proteins
enzymes, structural (alpha-keratin), transport (hemoglobin),…
condensation
peptide bond formation is a ____ reaction
23 terms
Molecular cell biology 3
Example of a checkpoint
Cancer cells immortality is by
Condensation reaction
Polar r group negatively charged posit…
If all spindles are not attached anaphase will not take place
No regulating phases divide and evade apoptosis , able to sec…
Attatchement if two monomers bond together through the loss o…
Serine/ aspartic/ lysine
Example of a checkpoint
If all spindles are not attached anaphase will not take place
Cancer cells immortality is by
No regulating phases divide and evade apoptosis , able to sec…
584 terms
Molecular and Cell Biology 3&4
Separates the inner and outer nuclear…
Outer nuclear membrane
Inner nuclear membrane
Nucleoplasm
Perinuclear space
Continuous with the ER lumen
Connects to nuclear lamina
Interior components of nucleus EXCEPT nucleolus
Separates the inner and outer nuclear…
Perinuclear space
Outer nuclear membrane
Continuous with the ER lumen
91 terms
Biology | Molecular Cell Exam 3
What are the functions of a plasma mem…
True or False: Only hydrophobic, uncha…
Fluid Mosaic Model
Integral Membrane vs. Peripheral Membr…
• Provides a barrier... • Concentrates solutes... • Provides struct…
True... ~ membrane is negatively charged
~ phospholipids move around... ~ proteins & other solutes get em…
Integral Membrane = outer & inner membrane... Peripheral Membran…
What are the functions of a plasma mem…
• Provides a barrier... • Concentrates solutes... • Provides struct…
True or False: Only hydrophobic, uncha…
True... ~ membrane is negatively charged
94 terms
Cell and Molecular Biology, Chapter 3
Coupling Endergonic and Exergonic reac…
Common intermediate
ATP hydrolysis
Roles for ATP hydrolysis in the cell
Formation of glutamine coupled with ATP hydrolysis; the downh…
Bridge between the two coupled reactions
ATP is converted to ADP & phosphate energized myosin heads (r…
Separate charge across a membrane... concentrate a particular so…
Coupling Endergonic and Exergonic reac…
Formation of glutamine coupled with ATP hydrolysis; the downh…
Common intermediate
Bridge between the two coupled reactions
56 terms
Cell and Molecular Biology Exam 3
What is the purpose of chaperones?
What region of a sarcomere only contai…
What makes up the backbone of DNA mole…
What is the difference between purines…
recognize and bind to the unfolded or misfolded proteins and…
I band
alternating phosphate and sugar groups
Purines - 2 rings (AG); Purine - 1 ring (CT)
What is the purpose of chaperones?
recognize and bind to the unfolded or misfolded proteins and…
What region of a sarcomere only contai…
I band
67 terms
Molecular Biology of the Cell Chapter 3
What constitutes most of the cell's dr…
Some Protein Functions (7+)
Another word for protein
Polypeptide Backbone
Proteins
-Catalyze... -Channels and pumps to control passage in/out of th…
Polypeptide
This is a fundamental chain that all amino acids have in comm…
What constitutes most of the cell's dr…
Proteins
Some Protein Functions (7+)
-Catalyze... -Channels and pumps to control passage in/out of th…
17 terms
Cell and Molecular Biology Chapter 3
Cell Theory
Cell Division
Bacteria
Characteristics of Bacteria
Schleiden & Schwann (1838-1839) ... All living cells are formed…
A cell reproduces by duplicating its DNA and dividing in two,…
Bacteria are the smallest and simplest cells. ... They often con…
Prokaryotic (before the nucleus)... Non membrane bound organelle…
Cell Theory
Schleiden & Schwann (1838-1839) ... All living cells are formed…
Cell Division
A cell reproduces by duplicating its DNA and dividing in two,…
77 terms
Molecular Biology of the Cell Exam 3
Mitochondria
Chloroplast
Tom Complex
Mitochondrial Hsp 70
-breaks down cards and fatty acids to make ATP via oxidative…
responsible for phtosynthesis ... -similar to mitochondria... -has…
-translocase of the outer membrane in mitochondria ... -then tra…
-chaperone that drives protein import into mitochondria ... -pro…
Mitochondria
-breaks down cards and fatty acids to make ATP via oxidative…
Chloroplast
responsible for phtosynthesis ... -similar to mitochondria... -has…
19 terms
Cell and Molecular Biology chapter 3
shaped like a v(2 hydrogens(partially…
overall charge of a molecule is uneven
linking together of like molecules; ma…
clinging of one substance to another,…
what is water?
what is a polar molecule?
what is cohesion?
what is adhesion?
shaped like a v(2 hydrogens(partially…
what is water?
overall charge of a molecule is uneven
what is a polar molecule?
39 terms
Molecular Cell Biology Chapter 3
energy that can be used to do work
increasing order in the cell _, which…
to decrease disorder requires an _ of…
there is a tendency toward higher _ in…
free energy (deltaG)
generates heat, increased
input
disorder
energy that can be used to do work
free energy (deltaG)
increasing order in the cell _, which…
generates heat, increased
51 terms
Cell & Molecular Biology Chapter 3
Carbon
Hydrocarbons
Functional Group
Isomers
Makes life possible because of its ability to form four coval…
Non-polar because of similar electronegativities... Hydrophobic…
Groups of atoms with characteristic chemical features and pro…
Two molecules with an identical formula but different structu…
Carbon
Makes life possible because of its ability to form four coval…
Hydrocarbons
Non-polar because of similar electronegativities... Hydrophobic…
126 terms
Test 3- cell and molecular biology
codon
initiation codon
property of codon- number in each codon
property of codon- beginning of transl…
3 nitrogenous base sequence that codes for 1 amino acid
AUG=methionine
always a triplet
translation always starts with the initiation codon
codon
3 nitrogenous base sequence that codes for 1 amino acid
initiation codon
AUG=methionine
54 terms
Cell and Molecular Biology exam 3
You are interested in studying muscle…
The action potential is very important…
You are weighing the components found…
When studying the outer leaflet of the…
Calcium channels found in the transverse tubules
Sodium
50:50
(phosphatidylcholine, sphingolipid, glycolipid) ... (phosphatid…
You are interested in studying muscle…
Calcium channels found in the transverse tubules
The action potential is very important…
Sodium
64 terms
Molecular Cell Biology Exam 3
what does "gene expression" govern?
describe stem cell differentiation
define "more differentiated" (broadly)
how may differentiation be induced?
which proteins are being produced
a stem cell divides, producing one more-differentiated daught…
exhibiting some change in gene expression... *in class: "differe…
by neighboring cells and/or hormones
what does "gene expression" govern?
which proteins are being produced
describe stem cell differentiation
a stem cell divides, producing one more-differentiated daught…
53 terms
Molecular Biology of the Cell Chapter 3
What constitutes most of the cell's dr…
Some Protein Functions (7+)
Another word for protein
Polypeptide Backbone
Proteins
-Catalyze... -Channels and pumps to control passage in/out of th…
Polypeptide
This is a fundamental chain that all amino acids have in comm…
What constitutes most of the cell's dr…
Proteins
Some Protein Functions (7+)
-Catalyze... -Channels and pumps to control passage in/out of th…
252 terms
theme 3 - molecular cell biology
how does a tRNA molecule bind?
why is the tRNA molecule modified?
what is the ribosomes function in tran…
where can ribosomes be found?
anticodon binds to RNA codon by complementary base pairing af…
to allow for folding
controls translation by joining subunits at start codon, inte…
endoplasmic reticulum (proteins for use within the cell) and…
how does a tRNA molecule bind?
anticodon binds to RNA codon by complementary base pairing af…
why is the tRNA molecule modified?
to allow for folding
78 terms
Molecular Cell Biology Ch. 3
3D protein structure derived from
What are the four structural hierarchi…
What groups form a peptide bond?
What type of reaction is linked to the…
AA & intramolecular noncovalent interactions
Primary AA sequence, Secondary A helix and B sheet, Tertiary…
Amino group and carboxyl group
Dehydration
3D protein structure derived from
AA & intramolecular noncovalent interactions
What are the four structural hierarchi…
Primary AA sequence, Secondary A helix and B sheet, Tertiary…
13 terms
Molecular cell biology 10/3
What are epigenetic modifications?
What does addition/removal of methyl g…
What does Xist do? Where is it located?
Is it good to have a "mosaic" of cells…
Modifications that impact gene expression such as histone mod…
Addition: DNA methyltransferase... Removal: Time, DNA excision/r…
It induces chromosome compaction to form a bar body. Xist non…
Yes! You get disease resistance. If one of your X chromosomes…
What are epigenetic modifications?
Modifications that impact gene expression such as histone mod…
What does addition/removal of methyl g…
Addition: DNA methyltransferase... Removal: Time, DNA excision/r…
29 terms
Molecular and Cell Biology Lecture 3
Four Structural Representations of SH2…
backbone
Ribbon
Wire
1. Backbone... 2. Ribbon... 3. Wire... 4. Space-filling
shows the organization of the polypeptide chain, a clean way…
an easy way to visualize secondary structure such as alpha he…
Highlights the side chains and their relative proximities
Four Structural Representations of SH2…
1. Backbone... 2. Ribbon... 3. Wire... 4. Space-filling
backbone
shows the organization of the polypeptide chain, a clean way…
19 terms
Cell and Molecular Biology Exam 3
Krebs, Fisher and Sutherland
Direct Cell-Cell Signaling
Endocrine signalling
Paracrine signalling
Cultured skeletal muscle cells and saw an increase of cAMP on…
Ligand not released, membrane bound, anchored to receiving ce…
Secreting and target cell far apart, using circulatory system…
Secreting cell and target cell are neighboring, in same tissu…
Krebs, Fisher and Sutherland
Cultured skeletal muscle cells and saw an increase of cAMP on…
Direct Cell-Cell Signaling
Ligand not released, membrane bound, anchored to receiving ce…
32 terms
Cell and Molecular Biology Quiz 3
Prokaryotes
Eukaryotes
Both Have
2 Forms of Prokaryotes
No nucleus or membrane-bound organelles (nucleoid, ribosomes,…
Has nucleus and membrane-bound organelles
Cytosol, chromosomes, ribosomes
Bacteria, archea
Prokaryotes
No nucleus or membrane-bound organelles (nucleoid, ribosomes,…
Eukaryotes
Has nucleus and membrane-bound organelles
21 terms
Cell & Molecular Biology Test 3
DNA sequencing
expression vectors
reporter gene
gene fluorescent protein
...
...
gene encoding a protein whose activity is easy to monitor exp…
(GFP) type of reporter protein
DNA sequencing
...
expression vectors
...
99 terms
Cell and Molecular Biology Exam 3
scientist: explorer
scientist: tinker
scientist: optimizer
scientist: summarizer
create a new framework of thinking, philosophical, artistic,…
develop the major techniques, ingenious, inventive, often rea…
use and adapt tools to new subjects, detail oriented, hard-wo…
capture the knowledge of the first three stages, repackage it…
scientist: explorer
create a new framework of thinking, philosophical, artistic,…
scientist: tinker
develop the major techniques, ingenious, inventive, often rea…
18 terms
Cell Molecular Biology Test 3
Flippases
NADPH
Newly synthesized phospholipids are ad…
A _______ gradient drives pyruvate imp…
catalyze the transfer of phospholipids from one side of the E…
is formed by the last protein in the photosynthetic electron…
cytoplasmic
proton
Flippases
catalyze the transfer of phospholipids from one side of the E…
NADPH
is formed by the last protein in the photosynthetic electron…
21 terms
Cell and Molecular Biology Exam 3
proplastids
chromoplasts
Outer membrane
inner membrane
pro-generate plastids in which plastids originated that can l…
(contain pigments); as fruit rises, the chlorophyll breaks do…
(chloroplast structure); highly permeable to small metabolite…
(chloroplast structure); not very permeable
proplastids
pro-generate plastids in which plastids originated that can l…
chromoplasts
(contain pigments); as fruit rises, the chlorophyll breaks do…
41 terms
exam 3 cell and molecular biology
O2
transmembrane protein
protein-attached
several amphipathic alpha helices... and…
molecules that diffuse readily across membranes
membrane proteins extends through the lipid bilayer
membrane proteins classified as a peripheral membrane
structures used by transmembrane proteins that form aqueous p…
O2
molecules that diffuse readily across membranes
transmembrane protein
membrane proteins extends through the lipid bilayer
18 terms
Cell & Molecular Biology Exam 3
Where do proteins that travel through…
What kind of glycosylation occurs in t…
What kind of glycosylation occurs in t…
What is receptor mediated endocytosis?
ER, golgi, lysosomes, endosomes, secretory vessels, plasma me…
N-Linked glycolysation is added to proteins
N-Linked glycosylation is modified, and O-Linked glycosylatio…
Form of pinocytosis, where molecules outside the cell bind to…
Where do proteins that travel through…
ER, golgi, lysosomes, endosomes, secretory vessels, plasma me…
What kind of glycosylation occurs in t…
N-Linked glycolysation is added to proteins
34 terms
Cell and Molecular Biology (Exam 3)
According to the base pairing rule, yo…
Which of the following is TRUE about h…
If a child belonged to blood type O, h…
The fur color of a Siamese cat (shown…
A and T
Human DNA's wrap around scaffold proteins
Type AB mother and type O father
Temperature sensitivity of the black allele
According to the base pairing rule, yo…
A and T
Which of the following is TRUE about h…
Human DNA's wrap around scaffold proteins
45 terms
molecular cell biology test 3
oxidative decarboxylation
aerobic respiration
cyclin dependent kinases
cyclins
In Pyruvate Dehyrogenase Complex and Krebs cycle in which a m…
conversion of chemical energy into organic molecule like gluc…
involved in cell cycle regulation, phoshorylate key proteins…
proteins that interact with cdks to provide subrstrate specic…
oxidative decarboxylation
In Pyruvate Dehyrogenase Complex and Krebs cycle in which a m…
aerobic respiration
conversion of chemical energy into organic molecule like gluc…
18 terms
Cell Molecular Biology Test 3
Flippases
NADPH
Newly synthesized phospholipids are ad…
A _______ gradient drives pyruvate imp…
catalyze the transfer of phospholipids from one side of the E…
is formed by the last protein in the photosynthetic electron…
cytoplasmic
proton
Flippases
catalyze the transfer of phospholipids from one side of the E…
NADPH
is formed by the last protein in the photosynthetic electron…
102 terms
Cell and Molecular Biology Test 3
What is the main advantage of eukaryot…
Cell membrane
What are the four major phospholipids…
Describe the structure of cholesterol.
They have subdivided internal membrane compartments which all…
-crucial for permeability of cell... -acts as the "gatekeeper"--…
1. phosphatidyl-ethanolamine ... 2. sphingomyelin ... 3. Sphingosin…
Polar head, connected to riding steroid ring structure (stiff…
What is the main advantage of eukaryot…
They have subdivided internal membrane compartments which all…
Cell membrane
-crucial for permeability of cell... -acts as the "gatekeeper"--…
223 terms
Molecular and cell biology: exam 3
Cell signaling in nature
Overview of eukaryotic cell signaling
Overview of eukaryotic cell signaling 2
Methods for studying signaling pathways
-detect nutrients... -detect energy and light sources... -monitor e…
-cell signaling: ... converting environmental input signals to…
-output cellular responses: ... cell division, differentiation/d…
-methods that examine cellular processes in response to speci…
Cell signaling in nature
-detect nutrients... -detect energy and light sources... -monitor e…
Overview of eukaryotic cell signaling
-cell signaling: ... converting environmental input signals to…
163 terms
Cell Molecular Biology Exam 3
Examples of single gene inheritance di…
Multifactorial disease examples
Aneuploidy disease examples
Mitochondrial disease examples
Sickle cell anemia, cystic fibrosis, Marfan's syndrome
Alzheimer's, cancer, heart disease... heritability
Down's Syndrome, Turner Syndrome
LHON, MERF (epilepsy), MELAS (dementia)
Examples of single gene inheritance di…
Sickle cell anemia, cystic fibrosis, Marfan's syndrome
Multifactorial disease examples
Alzheimer's, cancer, heart disease... heritability
63 terms
Cell and Molecular Biology (Exam 3)
The flow of ions through open channels…
Because ions are charged particles, th…
Driving force of an ion
Direction of the electrical force
Both the permeability of the channels to the ion, and the dri…
The concentration gradient and the electrical field across th…
The sum of the concentration force of the ion and the electri…
depends on the ion's charge
The flow of ions through open channels…
Both the permeability of the channels to the ion, and the dri…
Because ions are charged particles, th…
The concentration gradient and the electrical field across th…
35 terms
Exam 3- Cell and Molecular Biology
To have a hormone receptor system that…
What causes the beta and gamma subunit…
Microtubules can be initiated at.......
The process of down-regulation reduces…
Far below the Kd before the stimulation of hormone secretion
Beta and gamma subunits don't dissociate
Basal bodies
Partial inactivation of the receptors, often by phosphorylation
To have a hormone receptor system that…
Far below the Kd before the stimulation of hormone secretion
What causes the beta and gamma subunit…
Beta and gamma subunits don't dissociate
65 terms
molecular biology of the cell exam 3
reception transduction response
reception
Transduction
response
the three stages of cell signaling
a chemical signal binds to a cellular protein at the cell sur…
binding leads to a change in the receptor that triggers a ser…
the transduced signal triggers a specific cellular activity…
reception transduction response
the three stages of cell signaling
reception
a chemical signal binds to a cellular protein at the cell sur…
1,069 terms
Cell Molecular Biology Lodish Glossary
ABC transporter proteins
Acetyl
Acetyl CoA
Acetylcholine receptor
Membrane transport proteins that use ATP to transfer peptides…
CH3-C=O Functional group derived from acetic acid. Added to s…
Acetyl + CoA through a tioester group. Water-soluble molecule…
Membrane bound protein (ion channel) that when bound to acety…
ABC transporter proteins
Membrane transport proteins that use ATP to transfer peptides…
Acetyl
CH3-C=O Functional group derived from acetic acid. Added to s…
45 terms
Molecular Biology of the Cell Chapter 13 Part 3
Lysosome
Hydrolases
Lipases, nucleases, phosphatases, and…
Glycosylated
What membrane bound organelle is involved in intracellular di…
The lysosome contains >40 acid what which are active only at…
Besides the hydrolases, the lysosome contains what?
The membrane proteins of the lysosome are highly what?
Lysosome
What membrane bound organelle is involved in intracellular di…
Hydrolases
The lysosome contains >40 acid what which are active only at…
30 terms
Molecular Cell Biology Lecture 3 (Alzheimers)
What happens when mis-folded or partia…
How does Alzheimers relate to dementia?
Describe the pathology of Alzheimers
What are amyloid plaques?
They turn into an insoluble mess that cannot be un-messified.…
It is a major cause of dementia.
There is a reduced Brain mass. In an autopsy, you see this re…
Protein aggregates/"tangles" that are insoluable
What happens when mis-folded or partia…
They turn into an insoluble mess that cannot be un-messified.…
How does Alzheimers relate to dementia?
It is a major cause of dementia.
Biology Cell Sec. 3 and 4
cell wall
Peptidoglycan
chitin
cellulose
structure that surrounds some cells, provides protection and…
bacterical cell walls are made of
fungal cell walls are made of
plant cell walls are made of
cell wall
structure that surrounds some cells, provides protection and…
Peptidoglycan
bacterical cell walls are made of
99 terms
Molecular Cell Biology
lactose operon uses __________ control…
Lac I... When is it expressed?... What kind…
When O1 and O2/O3 are bound by the rep…
Lac O
combinatorial... polycistronic
repressor; expressed all of the time; it is a helix-turn-helix
loop, which hinders RNAP from initiating transcription
operator; binds the repressor
lactose operon uses __________ control…
combinatorial... polycistronic
Lac I... When is it expressed?... What kind…
repressor; expressed all of the time; it is a helix-turn-helix
135 terms
Cell and Molecular Biology
Activation Energy
Amino acid
Anaphase
ATP
The energy required to start a chemical reaction
An organic molecule possessing one carboxyl, one amino, and o…
The stage of mitosis in which sister chromatids are pulled ap…
Adenosine triphosphate, the main source of energy for cells
Activation Energy
The energy required to start a chemical reaction
Amino acid
An organic molecule possessing one carboxyl, one amino, and o…
45 terms
Molecular Biology of the Cell Chapter 13 Part 3
Lysosome
Hydrolases
Lipases, nucleases, phosphatases, and…
Glycosylated
What membrane bound organelle is involved in intracellular di…
The lysosome contains >40 acid what which are active only at…
Besides the hydrolases, the lysosome contains what?
The membrane proteins of the lysosome are highly what?
Lysosome
What membrane bound organelle is involved in intracellular di…
Hydrolases
The lysosome contains >40 acid what which are active only at…
45 terms
Molecular Biology of the Cell Chapter 13 Part 3
Lysosome
Hydrolases
Lipases, nucleases, phosphatases, and…
Glycosylated
What membrane bound organelle is involved in intracellular di…
The lysosome contains >40 acid what which are active only at…
Besides the hydrolases, the lysosome contains what?
The membrane proteins of the lysosome are highly what?
Lysosome
What membrane bound organelle is involved in intracellular di…
Hydrolases
The lysosome contains >40 acid what which are active only at…
33 terms
Biology: Cell and Molecular
Light Dependent Reaction
Light Independent Reaction "Calvin Cyc…
Lipases
Cytokinesis
-happens in thylakoid membrane... -convert light energy (photons…
-happens in stroma of chloroplast... -uses ATP and NADPH from Li…
enzymes that digest fats (glycerol backbone and fatty acids)
-occurs in animals... -splits cytoplasm into 2 cells... -microfilam…
Light Dependent Reaction
-happens in thylakoid membrane... -convert light energy (photons…
Light Independent Reaction "Calvin Cyc…
-happens in stroma of chloroplast... -uses ATP and NADPH from Li…
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