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Study sets matching "antibiotics"

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Study sets matching "antibiotics"

96 terms
Antibiotics
What are the patient factors to consid…
What the antibiotic factors to conside…
What is MIC?
What are the pharmaco-dynamic determin…
Site and source of infection... Likely cause of infection at sit…
Spectrum of activity... Method of administration... Penetration to…
Minimum Inhibitory Capacity - the concentration under standar…
Different parameters predict response to therapy for differen…
What are the patient factors to consid…
Site and source of infection... Likely cause of infection at sit…
What the antibiotic factors to conside…
Spectrum of activity... Method of administration... Penetration to…
96 terms
Antibiotics
What are the patient factors to consid…
What the antibiotic factors to conside…
What is MIC?
What are the pharmaco-dynamic determin…
Site and source of infection... Likely cause of infection at sit…
Spectrum of activity... Method of administration... Penetration to…
Minimum Inhibitory Capacity - the concentration under standar…
Different parameters predict response to therapy for differen…
What are the patient factors to consid…
Site and source of infection... Likely cause of infection at sit…
What the antibiotic factors to conside…
Spectrum of activity... Method of administration... Penetration to…
83 terms
Antibiotics
Gram stain
Gram stain coccobacilli
Coagulase test
Hemolysis test
Blood agar
Gram stain
Gram stain coccobacilli
31 terms
Antibiotics
CA-MRSA
CA-MRSA, Less Serous
Complicated Skin Infection... Suspected M…
Polymicrobial skin infections, could b…
Drug: Trimethoprim/Sulfametoxazole (Bactram)... ADR: ... -Hypersen…
I&D unless sever then Trimethoprim/Sulfametoxazole... ADR: ... -Hy…
Vancomycin... MOA:... Cell wall inhibitor, (block elongation)... ADR…
Piperacillin + Tazobactam... MOA: B-Lactam. Cell Wall Inhibitor…
CA-MRSA
Drug: Trimethoprim/Sulfametoxazole (Bactram)... ADR: ... -Hypersen…
CA-MRSA, Less Serous
I&D unless sever then Trimethoprim/Sulfametoxazole... ADR: ... -Hy…
19 terms
Antibiotics
Amoxicillin
Amoxicillin-Clavulanate
Moxifloxacin
Sulfamethoxazole-Trimethoprim
Amoxil, Trimox
Augmentin
Avelox
Bactrim, Septra
Amoxicillin
Amoxil, Trimox
Amoxicillin-Clavulanate
Augmentin
257 terms
Antibiotics
Aminoglycosides MOA
AMG - Concentration or Time
Aminoglycosides
When are aminoglycosides used?
bind to 30S and 50S part of ribosome (inhibition of protein s…
Concentration
-mycins, streptomycin, gentamicin, neomycin, tobramycin, rela…
Useful as adjunct treatment for serious infections (coverage…
Aminoglycosides MOA
bind to 30S and 50S part of ribosome (inhibition of protein s…
AMG - Concentration or Time
Concentration
42 terms
Antibiotics
Sulphonamides
Tetracyclines
Aminoglycosides
Aminoglycoside resistance
Acts but inhibiting folic acid synthesis
S-Subunit inibitors causing a missense/nonsense mutation
S-Subunit inibitors
add extra polar group to the molecule so to make it unable to…
Sulphonamides
Acts but inhibiting folic acid synthesis
Tetracyclines
S-Subunit inibitors causing a missense/nonsense mutation
19 terms
Antibiotics
Antibiotics exert their effects via 5…
Aminoglycans
Bacitracin... (Carbapenems)
Carbapenems
(1) Inhibition of cell wall synthesis (cephalosporins, penici…
-inhibits protein synthesis... -from Streptomyces and Micromnosp…
-from Bacillus, ... -highly toxic, ... -only used topically.
-broad spectrum w/ two-part structure. ... -Primaxin and cilasta…
Antibiotics exert their effects via 5…
(1) Inhibition of cell wall synthesis (cephalosporins, penici…
Aminoglycans
-inhibits protein synthesis... -from Streptomyces and Micromnosp…
126 terms
Antibiotics
If you have a Cardiothoracic surgery w…
If you have a Cardiothoracic surgery w…
If you have a Colorectal surgery what…
If you have a Colorectal surgery what…
Routine: Cefazolin... if MRSA: Cefazolin +vancomycin
Vancomycin + aztreonam ( routine & MRSA)
Ampicillin/sulbactam
Ciprofloxacin + metronidazole or... ciprofloxacin + clindamycin
If you have a Cardiothoracic surgery w…
Routine: Cefazolin... if MRSA: Cefazolin +vancomycin
If you have a Cardiothoracic surgery w…
Vancomycin + aztreonam ( routine & MRSA)
169 terms
Antibiotics
Beta-Lactam Antibiotics
MOA of Beta-Lactam Antibiotics
What are some methods of resistance th…
What are some subclasses Penicillin (P…
Penicillins... Cephalosporins... Carbapenems... Monobactams
Binds to PBP's --> activates bacterial autolytic enzymes that…
Beta-Lactamase (destroys the beta lactam ring → rendering ant…
Natural Penicillins... Antistaphylococcal Penicillins... Aminopenic…
Beta-Lactam Antibiotics
Penicillins... Cephalosporins... Carbapenems... Monobactams
MOA of Beta-Lactam Antibiotics
Binds to PBP's --> activates bacterial autolytic enzymes that…
24 terms
Antibiotics
Monobactams
Carbapenems
Glycopeptide
Daptomycin
Azetreonam... Bactericidal: inhibit penicillin binding proteins(…
Meropenem... Serious or highly resistant hospital infections... bro…
Vancomycin ... Use orally for C.difficile... Inhibits Cell wall syn…
Lipopeptide... BInds plasma membrane of gram positive organism i…
Monobactams
Azetreonam... Bactericidal: inhibit penicillin binding proteins(…
Carbapenems
Meropenem... Serious or highly resistant hospital infections... bro…
58 terms
Antibiotics
Penicillin G
Penicillin V
Ampicillin
Amoxicillin
Penem: beta-lactam with a 5-member ring with sulfur... ♣ benzene…
Penem: beta-lactam with a 5-member ring with sulfur... ♣ phenoxy…
Penem: beta-lactam with a 5-member ring with sulfur... ♣ Amine g…
Penem: beta-lactam with a 5-member ring with sulfur... ♣ Amine g…
Penicillin G
Penem: beta-lactam with a 5-member ring with sulfur... ♣ benzene…
Penicillin V
Penem: beta-lactam with a 5-member ring with sulfur... ♣ phenoxy…
109 terms
Antibiotics
What are the patient factors to consid…
What the antibiotic factors to conside…
What is MIC?
What are the pharmaco-dynamic determin…
Site and source of infection... Likely cause of infection at sit…
Spectrum of activity... Method of administration... Penetration to…
Minimum Inhibitory Capacity - the concentration under standar…
Different parameters predict response to therapy for differen…
What are the patient factors to consid…
Site and source of infection... Likely cause of infection at sit…
What the antibiotic factors to conside…
Spectrum of activity... Method of administration... Penetration to…
126 terms
Antibiotics
If you have a Cardiothoracic surgery w…
If you have a Cardiothoracic surgery w…
If you have a Colorectal surgery what…
If you have a Colorectal surgery what…
Routine: Cefazolin... if MRSA: Cefazolin +vancomycin
Vancomycin + aztreonam ( routine & MRSA)
Ampicillin/sulbactam
Ciprofloxacin + metronidazole or... ciprofloxacin + clindamycin
If you have a Cardiothoracic surgery w…
Routine: Cefazolin... if MRSA: Cefazolin +vancomycin
If you have a Cardiothoracic surgery w…
Vancomycin + aztreonam ( routine & MRSA)
169 terms
Antibiotics
Beta-Lactam Antibiotics
MOA of Beta-Lactam Antibiotics
What are some methods of resistance th…
What are some subclasses Penicillin (P…
Penicillins... Cephalosporins... Carbapenems... Monobactams
Binds to PBP's --> activates bacterial autolytic enzymes that…
Beta-Lactamase (destroys the beta lactam ring → rendering ant…
Natural Penicillins... Antistaphylococcal Penicillins... Aminopenic…
Beta-Lactam Antibiotics
Penicillins... Cephalosporins... Carbapenems... Monobactams
MOA of Beta-Lactam Antibiotics
Binds to PBP's --> activates bacterial autolytic enzymes that…
8 terms
Antibiotics
Penicillin and Cephalosporin
Sulfonamides and trimethoprim
synergistic effect
Aminoglycosides (streptomycin, gentami…
Block synthesis of peptidoglycan, causing the cell wall to lyse
Inhibit nucleic acid synthesis
Additive effect, achieved by multiple drugs working together,…
Block protein synthesis
Penicillin and Cephalosporin
Block synthesis of peptidoglycan, causing the cell wall to lyse
Sulfonamides and trimethoprim
Inhibit nucleic acid synthesis
10 terms
Antibiotics
antibiotics
Bacteria
microorganisms
biomass
Drugs that block the growth and reproduction of bacteria
(plural of bacterium) a group of very small living things tha…
Living creatures that are too small to see with the naked eye
Measure of the total dry mass of organisms in a given area
antibiotics
Drugs that block the growth and reproduction of bacteria
Bacteria
(plural of bacterium) a group of very small living things tha…
19 terms
Antibiotics
Amoxil, Trimox
Augmentin
Avelox
Bactrim, Septra
Amoxicillin
Amoxicillin-Clavulanate
Moxifloxacin
Sulfamethoxazole-Trimethoprim
Amoxil, Trimox
Amoxicillin
Augmentin
Amoxicillin-Clavulanate
181 terms
Antibiotics
What is the MOA of Penicillin G/V?
What Penicillin is Oral?... What Penicil…
What is the Clinical Usage of Penicill…
What Toxicity can Penicillin G/V produ…
- bind penicillin-binding proteins (transpeptidases)... -*block…
Oral:... - Penicillin V... IV:... - Penicillin G
Bateriocidal against:... - gram-pos organisms... - gram-neg cocci... -…
- Hypersensitivity rxn... -*Hemolytic anemia
What is the MOA of Penicillin G/V?
- bind penicillin-binding proteins (transpeptidases)... -*block…
What Penicillin is Oral?... What Penicil…
Oral:... - Penicillin V... IV:... - Penicillin G
42 terms
Antibiotics
Selective toxicity
Bacteriostatic... use
bactericidal... -use (2)
antibiotic vs antimicrobial
ability to kill or injure invading organisms without harming…
-inhibits bacterial growth... used when immune system can take…
killing of bacteria... use ... -during invasive infection... -immune…
antibiotic= natural... antimicrobial= synthetic
Selective toxicity
ability to kill or injure invading organisms without harming…
Bacteriostatic... use
-inhibits bacterial growth... used when immune system can take…
112 terms
Antibiotics
Penicillin: action
Where does penicillin bind to bacteria
are penicillins bacteriostatic or bact…
Why are penicillins generally safe to…
Weakens cell wall by disrupting synthesis ... Weakens cell wall…
at cell wall at PCN-Binding Proteins which are found during b…
bactericidal
Humans don't have cell walls
Penicillin: action
Weakens cell wall by disrupting synthesis ... Weakens cell wall…
Where does penicillin bind to bacteria
at cell wall at PCN-Binding Proteins which are found during b…
41 terms
Antibiotics
What's the appropriate antibiotic trea…
What's the appropriate antibiotic trea…
What's the appropriate antibiotic trea…
What's the appropriate antibiotic trea…
- Nafcillin... - Oxacillin... - Dicloxacillin... - Cephalexin... - Amoxic…
Mild:... - trimethoprim + sulfamethoxazole... Moderate:... - trimetho…
Allergic to β-lactams... - azithromycin... - clarithromycin... - clind…
Erysipelas... - penicillin V... - amoxicillin... - cephalexin
What's the appropriate antibiotic trea…
- Nafcillin... - Oxacillin... - Dicloxacillin... - Cephalexin... - Amoxic…
What's the appropriate antibiotic trea…
Mild:... - trimethoprim + sulfamethoxazole... Moderate:... - trimetho…
12 terms
Antibiotics
Penicillin
Vancomycin
tetracycline
sulfonamides
acts on cell wall synthesis
acts on cell wall synthesis
inhibit protein synthesis
antimetabolite action
Penicillin
acts on cell wall synthesis
Vancomycin
acts on cell wall synthesis
96 terms
Antibiotics
What are the patient factors to consid…
What the antibiotic factors to conside…
What is MIC?
What are the pharmaco-dynamic determin…
Site and source of infection... Likely cause of infection at sit…
Spectrum of activity... Method of administration... Penetration to…
Minimum Inhibitory Capacity - the concentration under standar…
Different parameters predict response to therapy for differen…
What are the patient factors to consid…
Site and source of infection... Likely cause of infection at sit…
What the antibiotic factors to conside…
Spectrum of activity... Method of administration... Penetration to…
57 terms
Antibiotics
Site of Action (image)
What is the difference between a macro…
What drugs interfere with *peptidoglyc…
What drugs interfere with *peptidoglyc…
Though they have similar names and both inhibit bacterial rib…
Penicillins... Cephalosporins... Carbapenems... Monobactams (aztreonam)
Glycopeptides (vancomycin, bacitracin)
Site of Action (image)
What is the difference between a macro…
Though they have similar names and both inhibit bacterial rib…
30 terms
ANTIBIOTICS
1st generation cephalosporins
Coverage 1st generation cephalosporins
2nd generation cephalosporins
Coverage 2nd generation cephalosporins
cefazolin... cefadroxil... cephalexin
Moraxella... E coli
cefoxitin... cefotetan... cefuroxime
1st generation coverage +... Providencia... Hemophilus... Klebsiella... C…
1st generation cephalosporins
cefazolin... cefadroxil... cephalexin
Coverage 1st generation cephalosporins
Moraxella... E coli
23 terms
Antibiotics
penicillin g
penicillin v
nafcillin
amoxicillin
Pfizerpen
Pen Vee K
Unipen
Amoxil
penicillin g
Pfizerpen
penicillin v
Pen Vee K
64 terms
antibiotics
antibiotics action
1-β-lactam antibiotics
2-mechanism of action
3-example of β-lactam antibiotics
1-Inhibition of Cell Wall Synthesis... a)Penicillins... b)Cephalosp…
β-lactam ring is present in each compound
1-Interfere with final cross-linking assembly step... 2- Disrupt…
Penicillins... .Cephalosporins
antibiotics action
1-Inhibition of Cell Wall Synthesis... a)Penicillins... b)Cephalosp…
1-β-lactam antibiotics
β-lactam ring is present in each compound
21 terms
Antibiotics
Define bactericidal antibiotics and li…
Define bacteriostatic antibiotics and…
Define time-dependent killing antibiot…
Define concentration-dependent killing…
Kill bacteria:... - Aminoglycosides... - Penicillins... - Cephalospori…
Inhibit growth of bacteria, allowing the immune system to eli…
Time above the minimum inhibitory concentration required in t…
High concentrations are required to kill bacteria (often 10x…
Define bactericidal antibiotics and li…
Kill bacteria:... - Aminoglycosides... - Penicillins... - Cephalospori…
Define bacteriostatic antibiotics and…
Inhibit growth of bacteria, allowing the immune system to eli…
31 terms
Antibiotics
Nitrofurantoin
Rifampin
Clindamycin
Trimethoprim/Sulfamehoxazole
Nitrofurantoin
Rifampin
15 terms
Antibiotics
Penicllins
Antistaph for beta lactam resistance
Broad spectrum penicllins
Antipeudomonas
Cell wall inhibitors
Methicillin, dicloxacillin, nafcillin
Ampicillin and amoxicillin
Piperacillin
Penicllins
Cell wall inhibitors
Antistaph for beta lactam resistance
Methicillin, dicloxacillin, nafcillin
42 terms
Antibiotics
antibiotics
Goals of antibiotic therapy
2 ways to classify antibiotics
Differences and Their Corresponding Dr…
Anti (Greek) = against; bios (Greek) = life... An umbrella term…
-To take advantage of differences in human (eukaryote) cells…
Classify by method of taking advantage of differences between…
Antibiotics can be classified by these differences between hu…
antibiotics
Anti (Greek) = against; bios (Greek) = life... An umbrella term…
Goals of antibiotic therapy
-To take advantage of differences in human (eukaryote) cells…
26 terms
Antibiotics
Penicillin Family
Bacitracin
Vancomycin
Carbapenems
Antibacterial Agent... M- inhibits cell wall synthesis ... P- Again…
Antibacterial agent... -Inhibits cell wall synthesis ... -against g…
Antibacterial Agent... -Inhibits cell wall synthesis ... -against a…
Antibacterial Agent... -Inhibits cell wall synthesis ... -life thre…
Penicillin Family
Antibacterial Agent... M- inhibits cell wall synthesis ... P- Again…
Bacitracin
Antibacterial agent... -Inhibits cell wall synthesis ... -against g…
110 terms
Antibiotics
beta lactam ring structure
resistant
Nitrocefin or Cefinase
Penicillins, Cephalosporins, Monobacta…
beta lactamase positive organisms are _____________ to beta l…
test for beta lactamase uses ____________________ disc: posit…
antibiotics containing beta lactam ring
beta lactam ring structure
resistant
beta lactamase positive organisms are _____________ to beta l…
5 terms
Antibiotics
Only one safe antibiotics in the pregn…
TMP-SMX is not good for the pregnent
Treatment for TB and their side effect…
Amphoteric in B vs azoles
Cephalexin, 1st cephalosproin, cover most bugs in UTI
consume Folic acid in the first trimester; compete for biliru…
Rifampin( RNA polymerase ), isoniazid, parazin-amide, etham-b…
Severe systemic fungus infection vs local or less severe syst…
Only one safe antibiotics in the pregn…
Cephalexin, 1st cephalosproin, cover most bugs in UTI
TMP-SMX is not good for the pregnent
consume Folic acid in the first trimester; compete for biliru…
113 terms
Antibiotics
Spectrum of Natural Penicillin
Spectrum of Penicillinase Resistant Pe…
Spectrum of Amino Penicillins
Spectrum Extended Spectrum Penicillins
Gram Positive
Resistant to hydrolysis by staphylococcal penicillinase and o…
Gram Positive and some gram negative (H. influenza)
Increased activity against Gram Negative Pseudomonas and Prot…
Spectrum of Natural Penicillin
Gram Positive
Spectrum of Penicillinase Resistant Pe…
Resistant to hydrolysis by staphylococcal penicillinase and o…
19 terms
antibiotics
hail
resistance
pave the way
soil
okrzyknąć
odporność
utorować drogę
gleba, ziemia
hail
okrzyknąć
resistance
odporność
73 terms
Antibiotics
1. Identify the antibiotics that targe…
1. Identify the antibiotics that targe…
1. Identify the antibiotics that targe…
2. Compare and apply the basic pharmac…
The Beta-lactams are the most commonly used antibiotics.
...
1. Identify the antibiotics that targe…
The Beta-lactams are the most commonly used antibiotics.
1. Identify the antibiotics that targe…
5 terms
Antibiotics
Sites of Antibiotics action
Describe three general ways that antib…
Explain the pharmacokinetics and pharm…
Describe the risks of inappropriate an…
1. Empirical/ initial therapy... - broad spectrum agent given un…
1. Pharmacokinetic factors:... - Absorption/ route of administra…
Emergence of antibiotic-resistant pathogens
Sites of Antibiotics action
Describe three general ways that antib…
1. Empirical/ initial therapy... - broad spectrum agent given un…
18 terms
Antibiotics
Amoxicillin
Azithromycin
Cefdinir
Cefuroxime
Amoxil
Zithromax, Z-Pak
Omnicef
Ceftin
Amoxicillin
Amoxil
Azithromycin
Zithromax, Z-Pak
20 terms
Antibiotics
Fluoroquinolone
Penicillin
Cephalosporin
Macrolide
Fluoroquinolone
Penicillin
15 terms
ANTIBIOTICS
Omnicef
Ceftin
Keflex
Cleocin
cefdinir - cephalosporin... watch for cross sensitivity to penic…
cefuroxime - cephalosporin... watch for cross sensitivity to pen…
cephalexin - cephalosporin... watch for cross sensitivity to pen…
clindamycin - lincosamide
Omnicef
cefdinir - cephalosporin... watch for cross sensitivity to penic…
Ceftin
cefuroxime - cephalosporin... watch for cross sensitivity to pen…
45 terms
Antibiotics
Sulfamethoxazole
Sulfisoxazole
Sulfadiazine
Trimethoprim
Sulfonamide - block folic acid synthesis
Sulfonamide - block folic acid synthesis
Sulfonamide - block folic acid synthesis
Sulfonamide - block folic acid synthesis
Sulfamethoxazole
Sulfonamide - block folic acid synthesis
Sulfisoxazole
Sulfonamide - block folic acid synthesis
32 terms
antibiotics
Beta-Lactam
Vancomycin
Bacitracin
cycloserine
penicillin... analog D-alanyl-D-alanine irreversibly binds to P…
binds directly to the D-alanine-D-alanine preventing the tetr…
blocks BACTOPRENOL preventing shuttling NAM and NAG across in…
blocks conversion of L-alanine to D-alanine and linkage of D-…
Beta-Lactam
penicillin... analog D-alanyl-D-alanine irreversibly binds to P…
Vancomycin
binds directly to the D-alanine-D-alanine preventing the tetr…
49 terms
Antibiotics
Carbapenems--broadest spectrum of B-La…
action of carbapenems
Monobactams
activity of monobactams
meropenem, doripenem
treat gram-negative organisms, gram positive organisms and an…
aztreonam (Azactam)
treat gram negative organisms including peudomonas sp.
Carbapenems--broadest spectrum of B-La…
meropenem, doripenem
action of carbapenems
treat gram-negative organisms, gram positive organisms and an…
27 terms
Antibiotics
Macrobid
Bactrim
Septra
Amoxil
nitrofurantoin... Nitrofuran
sulfamethoxazole/trimethoprim... Sulfa
sulfamethoxazole/trimethoprim... Sulfa
amoxicillin... combination penicillin
Macrobid
nitrofurantoin... Nitrofuran
Bactrim
sulfamethoxazole/trimethoprim... Sulfa
14 terms
ANTIBIOTICS
gentamicyn
ertapenem
cefaclor
cefditoren
aminoglycoside... -auruginosa, coli, proteus, klebsiella, citrob…
carbopenem... -Hospital A.pneumo, GI complications, pelvic infec…
cephalosporin (A+T) anthrax thyphoid 1/2 BOX... -surgical, respi…
cephalosporinn ... -bronchitis, derma, pharyngitis, tonsils t=(T…
gentamicyn
aminoglycoside... -auruginosa, coli, proteus, klebsiella, citrob…
ertapenem
carbopenem... -Hospital A.pneumo, GI complications, pelvic infec…
85 terms
Antibiotics
penicillin MOA, PK
penicillin static/cidal, conc/ time
penicillin PAE
penicillin toxicity
covalently bind PBPs bacterial transpeptidase... short half-life…
cidal, time
...
rash, anaphylaxis... pencillin allergy to beta-lactam... cephalospo…
penicillin MOA, PK
covalently bind PBPs bacterial transpeptidase... short half-life…
penicillin static/cidal, conc/ time
cidal, time
47 terms
Antibiotics
Antibiotic
Bacteriocidal
Bacteriostatic
Selective Toxicity
chemical agent produced by a microrganism that inhibits growt…
antibiotic activity that results in death of bacteria
arrests growth of bacteria
an antimicrobial effect that is directed at bacterial enzymes…
Antibiotic
chemical agent produced by a microrganism that inhibits growt…
Bacteriocidal
antibiotic activity that results in death of bacteria
24 terms
Antibiotics
Monobactams
Carbapenems
Glycopeptide
Daptomycin
Azetreonam... Bactericidal: inhibit penicillin binding proteins(…
Meropenem... Serious or highly resistant hospital infections... bro…
Vancomycin ... Use orally for C.difficile... Inhibits Cell wall syn…
Lipopeptide... BInds plasma membrane of gram positive organism i…
Monobactams
Azetreonam... Bactericidal: inhibit penicillin binding proteins(…
Carbapenems
Meropenem... Serious or highly resistant hospital infections... bro…
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