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Study sets matching "cancer chapter 10"

13 terms
Chapter 10 - Oncology (Cancer)
-oma
-plasia
-therapy
blast/o
suffix for mass, tumor - neuroblastoma
suffix for formation, growth - neoplasia
suffix for treatment - chemotherapy
root for immature, embryonic - neoblastoma
-oma
suffix for mass, tumor - neuroblastoma
-plasia
suffix for formation, growth - neoplasia
10 terms
Chapter 10 Mutations and Cancer
benign
malignant
mutation
mutagen
noncancerous tumor that will not spread throughout the body
a cancerous tumor that spreads throughout the body
a change in the nucleotide sequence of DNA
any chemical or physical agent that can damage DNA by changin…
benign
noncancerous tumor that will not spread throughout the body
malignant
a cancerous tumor that spreads throughout the body
9 terms
Chapter 10: Mutations and Cancer
Benign Tumor
Carcinogen
Germ-Line Mutation
Malignant Tumor
A noncancerous tumor that will not spread throughout the body.
Any chemical agent that causes cancer by damaging DNA. Carcin…
A mutation occurring in gametes; passed on to offspring.
A cancerous tumor that spreads throughout the body.
Benign Tumor
A noncancerous tumor that will not spread throughout the body.
Carcinogen
Any chemical agent that causes cancer by damaging DNA. Carcin…
25 terms
Cancer Biology Chapter 10
stem cells
progenitor cells
cells in replicative senescence
Hallmarks of senescence
self-renewing... dedifferentiated... immortal
comes from stem cells... differentiated... post mitotic
stopped dividing... G0 phase... remains alive in growth factors tho…
large cytoplasm... expression of B-galactosidase... SAHF's (senesce…
stem cells
self-renewing... dedifferentiated... immortal
progenitor cells
comes from stem cells... differentiated... post mitotic
16 terms
Chapter 10 Cancer
Benign
Beta-carotene
Cancer
Carcinogen
remain localized, less threatening
form of vitamin A found in carrots and sweet potatoes, lowers…
group of diseases characterized by the presence of new cells…
food that is suspected to be cancer causing
Benign
remain localized, less threatening
Beta-carotene
form of vitamin A found in carrots and sweet potatoes, lowers…
45 terms
Chapter 10: Cancer
Growth rate of benign tumor
Growth rate of malignant tumor
Character of growth of benign tumor
Character of growth of malignant tumor
Slow
Fast
Expansion
Infiltration
Growth rate of benign tumor
Slow
Growth rate of malignant tumor
Fast
37 terms
Chapter 10 Cancer
Malignant
Benign
Four main groups of malignant growths
Cancers with decreasing death rates
- spread; usually more dangerous because they can invade and…
- remain localized; usually less threatening
Carcinomas - cancers of the epithelial tissue... Sarcomas - canc…
Lung (men), breast, prostate, colon/rectum cancer
Malignant
- spread; usually more dangerous because they can invade and…
Benign
- remain localized; usually less threatening
10 terms
Biology Chapter 10 Mutations and Cancer
benign
malignant
mutation
mutagen
noncancerous tumor that will not spread throughout the body
a cancerous tumor that spreads throughout the body
a change in the nucleotide sequence of DNA
any chemical or physical agent that can damage DNA by changin…
benign
noncancerous tumor that will not spread throughout the body
malignant
a cancerous tumor that spreads throughout the body
12 terms
Chapter 10 Mutations & Cancer
Cancer
Mutation
allele
Germ-Line Mutation
disease of uncontrolled cell division
change in nucleotide sequence of DNA. Affects structure and f…
Alternative form of gene.
occurs in gametes and is passed on to offspring. In every cel…
Cancer
disease of uncontrolled cell division
Mutation
change in nucleotide sequence of DNA. Affects structure and f…
16 terms
Chapter 10 - Mutations & Cancer
Cancer
BRCA 1
BRCA 2
BRCA Genes
A disease of uncontrolled cell division
Located in chromosome 17
Located in chromosome 13
Mutation that increase the risk on developing breast cancer
Cancer
A disease of uncontrolled cell division
BRCA 1
Located in chromosome 17
15 terms
Definitions Chapter 10- Cancer Epidemiology
Define individual Carcinogens
Transgenerational Inheritance
Transgenerational Effects
Developmental Plasticity
cancer causing substances
The heritable transmission to future generations of environme…
An epigenetic alteration in sex cells
A degree to which an organism's development is dependent on i…
Define individual Carcinogens
cancer causing substances
Transgenerational Inheritance
The heritable transmission to future generations of environme…
63 terms
Chapter 10: Cancer Epidemiology
what cancers have increased substantia…
3 epigenetic processes
transgenerational inheritance
developmental pasticity
melanoma, NHL, testicular, brain, and thyroid
1) methylation ... 2) histone modifications... 3) miRNAs
inheritance of environmental linked genetic changes via germl…
how much an organisms development is contingent on the enviro…
what cancers have increased substantia…
melanoma, NHL, testicular, brain, and thyroid
3 epigenetic processes
1) methylation ... 2) histone modifications... 3) miRNAs
14 terms
Chapter 10: Cancer
Benign
Malignant
Carcinoma
Sarcoma
Noncancerous- tumors tend to remain localized and usually do…
Cancerous- tumors consist of renegade cells that do not respo…
cancer of the epithelial cells that line the outer and inner…
cancer that strikes muscles, bones, and cartilage
Benign
Noncancerous- tumors tend to remain localized and usually do…
Malignant
Cancerous- tumors consist of renegade cells that do not respo…
Chapter 10 Cancer (Health)
Regulatory Genes
Oncogenes
Proto-Oncogenes
Three Mechanisms
Genes that control cell specialization, replication, DNA repa…
Faculty regulatory genes believed to activate the development…
Normal regulatory genes that may become oncogenes
•Genetic mutations... -Miscopying of genes during cell division…
Regulatory Genes
Genes that control cell specialization, replication, DNA repa…
Oncogenes
Faculty regulatory genes believed to activate the development…
12 terms
Chapter 10: Mutations and Cancer
Mutation
Germ-line mutation
Somatic mutatuon
Function protuen
Change in the nucleotide sequence of DNA
A mutation occurring in the gametes; passed on to offspring
A mutation that occurs in a body (non-gamete) cell; not passe…
In its normal form, this protein regulates the cell cycle
Mutation
Change in the nucleotide sequence of DNA
Germ-line mutation
A mutation occurring in the gametes; passed on to offspring
14 terms
Chapter 10: Cancer Epidemiology
Although cancer arises from a complica…
(epigenetics and genetics)
Epigenetic changes collaborate with ge…
The three major types of epigenetic pr…
carcinogens
...
development of cancer.
methylation, histone modifications, and micro-RNAs (miRNAs)
Although cancer arises from a complica…
carcinogens
(epigenetics and genetics)
...
17 terms
Chapter 10: Viruses and Cancer
Cancer
Carcinogens
Sarcoma
Rous sarcoma virus (RSV)
the uncontrolled growth of a single cell that eventually form…
a substance capable of causing cancer in living tissue
slow-growing solid tumor
...
Cancer
the uncontrolled growth of a single cell that eventually form…
Carcinogens
a substance capable of causing cancer in living tissue
12 terms
Chapter 10 Cancer and Other
Benign Tumor
Malignant Tumor
1. Surgery 2. Radiation 3. Chemotherapy
23
Non-Cancerous Tumor
Cancerous Tumor
What are 3 treatments for cancer?
What is the human Haploid Number?
Benign Tumor
Non-Cancerous Tumor
Malignant Tumor
Cancerous Tumor
14 terms
Chapter 10 Mutations and Cancer
mutation
Proto-oncogene
Oncogene
tumor suppressor
a change in the nucleotide sequence of DNA
- A gene that codes for a protein that helps cells divide nor…
-A mutated and overactive form of a proto-oncogene.... -Drive ce…
- A gene that codes for proteins that monitor and check cell…
mutation
a change in the nucleotide sequence of DNA
Proto-oncogene
- A gene that codes for a protein that helps cells divide nor…
263 terms
Chapter 10 and cancer biology
splitting of cytoplasm into two cells
what determines cell division (reprodu…
how much DNA in each cell?
What are the two problems that cells f…
cytokinesis
limits to cell size
2 meters
information overload and exchanging materials
splitting of cytoplasm into two cells
cytokinesis
what determines cell division (reprodu…
limits to cell size
60 terms
Chapter 10 Cancer
10 hallmarks of cancer... acquired biolog…
self sufficiency in growth signaling... e…
insensitivity to signals pressuring gr…
ability to avoid apoptosis... examples of…
1. self sufficiency in growth signaling... 2. insensitivity to s…
activate cellular oncogene
inactivate TP53 to avoid p53-mediated cell cycle arrest
produce IGF survival factor
10 hallmarks of cancer... acquired biolog…
1. self sufficiency in growth signaling... 2. insensitivity to s…
self sufficiency in growth signaling... e…
activate cellular oncogene
62 terms
Chapter 10: Biology of Cancer
Adenocarcinoma
Adjuvant chemotherapy
Anaplasia
Angiogenesis
Malignant tumor of glandular epithelium.
...
...
...
Adenocarcinoma
Malignant tumor of glandular epithelium.
Adjuvant chemotherapy
...
43 terms
Biology of Cancer-Chapter 10
Malignant Tumor
Benign Tumor
Carcinoma
Adenocarcinomas
-not well differentiated, non encapsulated, invasive, rapid g…
-slow growing, encapsulated, non-invasive, well differentiate…
Originate in the epithelial tissue
Arise from or form ductal or glandular structures.
Malignant Tumor
-not well differentiated, non encapsulated, invasive, rapid g…
Benign Tumor
-slow growing, encapsulated, non-invasive, well differentiate…
17 terms
Chapter 10 Mutations and Cancer
Cancer
Genes BRCA1 and BRCA 2
Mutation
Allele
Disease of uncontrolled cell division
located on chromosome 17 and 13... mutation increases risk of de…
-change in the nucleotide sequence of DNA... -Affects structure…
alternative form of a gene... Mutations give rise to alleles ... Nu…
Cancer
Disease of uncontrolled cell division
Genes BRCA1 and BRCA 2
located on chromosome 17 and 13... mutation increases risk of de…
39 terms
Mutations and cancer chapter 10
Cancer
Genes BRCA1 and BRCA 2
Mutation
Allele
disease of uncontrolled cell division
located on chromosome 17 and 13... mutation increases risk of de…
change in the nucleotide sequence of DNA... Affects structure an…
alternative form of a gene... Mutations give rise to alleles ... Nu…
Cancer
disease of uncontrolled cell division
Genes BRCA1 and BRCA 2
located on chromosome 17 and 13... mutation increases risk of de…
14 terms
Chapter 10: cancer
A 50-year-old female develops skin can…
Which of the following patients would…
A nurse is preparing to teach the most…
Which of the following compounds has b…
Basal cell carcinoma
Light complexion, light eyes, fair hair
Leukemia
Alcohol
A 50-year-old female develops skin can…
Basal cell carcinoma
Which of the following patients would…
Light complexion, light eyes, fair hair
Biology of Cancer-Chapter 10
Malignant Tumor
Benign Tumor
Carcinoma
Adenocarcinomas
-not well differentiated, non encapsulated, invasive, rapid g…
-slow growing, encapsulated, non-invasive, well differentiate…
Originate in the epithelial tissue
Arise from or form ductal or glandular structures.
Malignant Tumor
-not well differentiated, non encapsulated, invasive, rapid g…
Benign Tumor
-slow growing, encapsulated, non-invasive, well differentiate…
10 terms
Chapter 10: Mutations and Cancer
mutation
germ-line mutation
somatic mutation
mutagen
a change in the nucleotide sequence of DNA
a mutation occurring in gametes (passed on to offspring)
a mutation that occurs in a body (nongamete) cell (not passed…
any chemical or physical agent that can damage DNA by changin…
mutation
a change in the nucleotide sequence of DNA
germ-line mutation
a mutation occurring in gametes (passed on to offspring)
10 terms
Chapter 10: Mutation and Cancer
Mutation
Germ-Line Mutation
Somatic Mutation
Mutagen
a change in the nucleotide sequence of DNA
a mutation occurring in gametes; passed on to offspring
a mutation that occurs in a body (nongamete) cell; not passed…
any chemical or physical agent that can damage DNA by changin…
Mutation
a change in the nucleotide sequence of DNA
Germ-Line Mutation
a mutation occurring in gametes; passed on to offspring
8 terms
Biology of Cancer Chapter 10
RB Gene
P53 Gene
APC Gene
TGFB-Smad
--Cell cycle, phosphorlytation allows to pass G1 step... Ras-MA…
-- DNA damage, phosphorlyation turns on 2 step of cycle arres…
-- receptor stimulates nuclear cell proliferation when protei…
--loss of function leads to epethilial cell proliferation... P1…
RB Gene
--Cell cycle, phosphorlytation allows to pass G1 step... Ras-MA…
P53 Gene
-- DNA damage, phosphorlyation turns on 2 step of cycle arres…
12 terms
Chapter 10 - Biology of Cancer
Benign tumors use which suffix?
Anaplasia
Carcinomas
Sarcoma
-oma
loss of cell differentiation
epithelial tissue cancer
connective, tissue, muscle, bone cancers
Benign tumors use which suffix?
-oma
Anaplasia
loss of cell differentiation
10 terms
Chapter 10- Mutations and Cancer
Mutations
Germ-Line Mutation
Somatic Mutation
Mutagens
change in the nucleotide sequence of DNA
mutation occurring in gametes; passed on to offspring
mutation that occurs in a body (nongamete) cell; not passed o…
any chemical or physical agent that can damage DNA by changin…
Mutations
change in the nucleotide sequence of DNA
Germ-Line Mutation
mutation occurring in gametes; passed on to offspring
51 terms
Chapter 10: Immunity and Cancer
Immune System Function
Immune system has what types of effects?
Innate immunity
Adaptive immunity
Protects host from infectious agents and promotes repair of t…
Anti-tumor: Recognition and destruction of tumor cells and vi…
Early, non-specific immune response, mediated by immune cells…
Specific! Occurs later and is mediated by T and B cells.
Immune System Function
Protects host from infectious agents and promotes repair of t…
Immune system has what types of effects?
Anti-tumor: Recognition and destruction of tumor cells and vi…
10 terms
Pathophysiology Chapter 10 Cancer Epidemiology
transgenerational inheritance
developmental plasticity
xenobiotics
bystander effects
the heritable transmission to future generations of environme…
the degree to which an organism's development is contingent o…
compounds including toxic, mutagenic, and carcinogenic chemic…
genetic effects in so-called bystander cells or innocent cell…
transgenerational inheritance
the heritable transmission to future generations of environme…
developmental plasticity
the degree to which an organism's development is contingent o…
117 terms
Virology: Chapter 10 Cancer
What did hippocrates observe?
What cancer were chimney sweeps associ…
Where was the 1st cancer hospital loca…
How many cancers are associated with v…
carcinomas
scrotal cancer
Reims, Fracne
20%
What did hippocrates observe?
carcinomas
What cancer were chimney sweeps associ…
scrotal cancer
15 terms
Chapter 10- Cancer Epidemiology
30%
Squamous and Small Cell
60
respiratory and GI
Smoking is associated with ___% of all cancer deaths.
Smoking is associated with _______ and _____ ____ adenocarcin…
___ chemicals present in cigarette smoke are considered carci…
Bidi smoking has been assocaited with cancer of ____ and ____…
30%
Smoking is associated with ___% of all cancer deaths.
Squamous and Small Cell
Smoking is associated with _______ and _____ ____ adenocarcin…
17 terms
CHAPTER 10: Mutations and Cancer
MUTATION
GERM-LINE MUTATION
SOMATIC MUTATION
ALLELE
...
...
...
alternative versions of the same gene, for every one gene the…
MUTATION
...
GERM-LINE MUTATION
...
11 terms
Chapter 10 - Mutations and Cancer
Benign Tumor
Malignant Tumor
Mutation
Mutagen
noncancerous tumor that will not spread throughout the body
a cancerous tumor that spreads throughout the body
a change in the nucleotide sequence of DNA
any chemical or physical agent that can damage DNA by changin…
Benign Tumor
noncancerous tumor that will not spread throughout the body
Malignant Tumor
a cancerous tumor that spreads throughout the body
34 terms
Cancer: Chapter 10 Biology
What do Cancer cells Lack?
Cell Differentiation
Who discovered Cancer?
Hippocrates
Cell differentiation
The cancer cell no longer knows what its job is in the human…
Hippocrates
found a breast tumor that looked like a crab. "The Father of…
What do Cancer cells Lack?
Cell differentiation
Cell Differentiation
The cancer cell no longer knows what its job is in the human…
18 terms
Cancer Epidemiology Chapter 10
Xenobiotic
Foods that increase cancer risk
Environmental Risk Factors: Alcohol Co…
Environmental Risk Factors: Ionizing R…
a chemical compound (as a drug, pesticide, or carcinogen) tha…
Fat (especially large amounts of omega-6 fatty acids); high-g…
Risk factor fora:... --oral cavity... --pharynx... -- hypopharynx... --la…
--Emission from x-rays, radioisotopes, radon, and other radio…
Xenobiotic
a chemical compound (as a drug, pesticide, or carcinogen) tha…
Foods that increase cancer risk
Fat (especially large amounts of omega-6 fatty acids); high-g…
10 terms
Chapter 10 Cancer Epidemiology
What increases the number of cancer ca…
What are the majority of cancers cause…
What cancers are increasing in U.S
Cigarette smoking causes what
Environmental , lifestyle factors and occupational exposure .
Carcinogen exposure.
*Melanoma... *non-hodgkin lymphoma... *Testicular... *Brain... *Thyroid…
5 million deaths per yr.... Cancer of the lung, lower urinary t…
What increases the number of cancer ca…
Environmental , lifestyle factors and occupational exposure .
What are the majority of cancers cause…
Carcinogen exposure.
19 terms
Chapter 10: Cancer Epidemiology
risk for cancer
epigenetics
tobacco
diet
can occur because of genes (such as breast cancer with the BR…
change in genetic expression without DNA mutation (DNA methyl…
multipotent carcinogenic mixture linked to cancers of the lun…
may account for 30% of the overall risk factors for cancer.... x…
risk for cancer
can occur because of genes (such as breast cancer with the BR…
epigenetics
change in genetic expression without DNA mutation (DNA methyl…
40 terms
Chapter 10 Biology of Cancer
cancer
benign tumor characteristics
malignant tumor characteristics
benign tumor classification
diseases in which abnormal cells divide without control and a…
grow slowly, well-defined capsule, not invasive, well differe…
grow rapidly, not encapsulated, invasive, poorly differentiat…
named according to the tissues from which they arise and incl…
cancer
diseases in which abnormal cells divide without control and a…
benign tumor characteristics
grow slowly, well-defined capsule, not invasive, well differe…
16 terms
Chapter 10 Mutations and Cancer
Cancer
Mutation
Allele
Germ line mutation occurs in?
Disease of uncontrolled cell division
Change in the nucleotide sequence of DNA. Affects structure &…
Alternative form of a gene. Mutations give arise to alleles.…
In gametes and is passed on to the offspring
Cancer
Disease of uncontrolled cell division
Mutation
Change in the nucleotide sequence of DNA. Affects structure &…
9 terms
Chapter 10: Mutations and Cancer
Benign Tumor
Carcinogen
Germ-Line Mutation
Malignant Tumor
A noncancerous Tumor that will not spread throughout the body
Any chemical agent that causes cancer by damaging DNA. These…
A mutation occurring in gametes; passed on to offspring
A cancerous tumor that spreads throughout the body
Benign Tumor
A noncancerous Tumor that will not spread throughout the body
Carcinogen
Any chemical agent that causes cancer by damaging DNA. These…
10 terms
Pathophysiology Chapter 10 Cancer Epidemiology
transgenerational inheritance
developmental plasticity
xenobiotics
bystander effects
the heritable transmission to future generations of environme…
the degree to which an organism's development is contingent o…
compounds including toxic, mutagenic, and carcinogenic chemic…
genetic effects in so-called bystander cells or innocent cell…
transgenerational inheritance
the heritable transmission to future generations of environme…
developmental plasticity
the degree to which an organism's development is contingent o…
21 terms
Chapter 10 Mutations and Cancer
Cancer
BRCA1 and BRCA2 genes
Mutation
Cancer can result if...
disease of uncontrolled cell division
-located on chromosome 17 and 13... -mutation of these genes inc…
-change in the nucleotide sequence of DNA... -affects structure…
cancer can result if mutation affects normal functioning of c…
Cancer
disease of uncontrolled cell division
BRCA1 and BRCA2 genes
-located on chromosome 17 and 13... -mutation of these genes inc…
44 terms
Chapter 10- Bio of Cancer.
Tumor Supressor Gene
What type of experiment provided the f…
When would a hybrid cell revert back t…
After a single copy of a TSG has under…
A gene whose function is to inhibit cell proliferation or pro…
Cell Fusion Experiments. ... -When a cancer cell was fused with…
Once normal cells loses a particular chromosome containing th…
Phenomenon known as Loss of Heterozygosity- where a mechani…
Tumor Supressor Gene
A gene whose function is to inhibit cell proliferation or pro…
What type of experiment provided the f…
Cell Fusion Experiments. ... -When a cancer cell was fused with…
17 terms
PSYC 335 Chapter 10: Cancer
Cancer
Metastasis
Carcinoma
Sarcoma
A set of diseases in which abnormal body cells multiply and s…
The process by which malignant body cells proliferate in numb…
Cancer of the epithelial cells that line the outer and inner…
Cancer that strikes muscles, bones, and cartilage
Cancer
A set of diseases in which abnormal body cells multiply and s…
Metastasis
The process by which malignant body cells proliferate in numb…
27 terms
Chapter 10: Biology of Cancer
Upon review of a client's chart, the n…
Which information indicates the nurse…
A client is receiving radiation and as…
A nurse is teaching about characterist…
4. The client is at increased risk for breast cancer.
3... Cancer refers to a malignant tumor.
3... Radiation is used to kill cancer cells while minimizing dam…
1,4 and 5
Upon review of a client's chart, the n…
4. The client is at increased risk for breast cancer.
Which information indicates the nurse…
3... Cancer refers to a malignant tumor.
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