Study sets matching "cancer"

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Study sets matching "cancer"

21 terms
cancer
Paraplatin
Leukeran
Cytoxan
Zanosar
carboplatin
chlorambucil
cyclophosphamide
streptozocin
Paraplatin
carboplatin
Leukeran
chlorambucil
83 terms
Cancer
parotid enlargement mcc
parotid tumor mcc
TNF-alpha
IL-1
mumps
pleomorphic adenoma
responsible for cachexia/shock
responsible for fever
parotid enlargement mcc
mumps
parotid tumor mcc
pleomorphic adenoma
12 terms
Cancer
Cancer risk factors
Name cancer's seven warning signals (C…
By what mechanisms does metastasis occur
How does a biopsy differ from an endos…
Radiation exposure, obesity, high fat diet, sun exposure, vir…
Change in Bowel or bladder habit... A sore that does not heal... Un…
1) Diffusion into other body cavities 2) Circulation via bloo…
Biopsies take a sample of a tissue and an endoscopy visualize…
Cancer risk factors
Radiation exposure, obesity, high fat diet, sun exposure, vir…
Name cancer's seven warning signals (C…
Change in Bowel or bladder habit... A sore that does not heal... Un…
Cancer
The nurse is giving a group presentati…
The nurse is teaching a 47-year-old wo…
A 72-year-old client recovering from l…
The nurse reviews the chart of a clien…
D. "I need to report the pain going down my legs to my health…
A. "My mother and grandmother had breast cancer, so I am at r…
D. Advancing age... Advancing age is the single most important…
B. "The brain tumor measures about 1 to 2 cm and shows no reg…
The nurse is giving a group presentati…
D. "I need to report the pain going down my legs to my health…
The nurse is teaching a 47-year-old wo…
A. "My mother and grandmother had breast cancer, so I am at r…
Cancer
They are genes that regulate cellular…
they are the mutated forms of proto-on…
nitrosamines are consumed after eating…
1. Radiationn and chemical carcinogens…
what are proto-oncogenes?
what are oncogenes?
what is nitrosamine? what does it do?
what are three mechanisms in which proto-oncogenes can be tur…
They are genes that regulate cellular…
what are proto-oncogenes?
they are the mutated forms of proto-on…
what are oncogenes?
Cancer
Carcinomas- most breast cancers
Adenocarcinoma- often type of breast ca
Sarcoma
Ductal carcinoma in situ
Type of cancer that starts in the cells (epithelial cells) th…
Carcinoma that starts in glandular tissue
Carcinoma that starts in cells of muscle, fat, or connective…
DCIS aka Intraductal carcinoma. Noninvasive or pre-invasive b…
Carcinomas- most breast cancers
Type of cancer that starts in the cells (epithelial cells) th…
Adenocarcinoma- often type of breast ca
Carcinoma that starts in glandular tissue
120 terms
Cancer
Li-Fraumeni Syndrome
Familial adenomatous polyposis
Ras
Familial neurofibromatosis type 1
Autosomal dominant disorder. Defect in one p53 allele.
Autosomal dominant disorder, resulting in colon cancer. Defec…
Single point mutation found in 30% of cancers. Most common on…
GAP mutation. Fails to catalyze Ras to turn itself off.
Li-Fraumeni Syndrome
Autosomal dominant disorder. Defect in one p53 allele.
Familial adenomatous polyposis
Autosomal dominant disorder, resulting in colon cancer. Defec…
50 terms
Cancer
staging
stomatitis
differentiation
T
The process of determining the extent of a cancer, including…
Inflammation of the oral tissues, often associated with some…
Development of functions and characteristics that are differe…
This letter refers to the extent of a primary tumor growth.
staging
The process of determining the extent of a cancer, including…
stomatitis
Inflammation of the oral tissues, often associated with some…
24 terms
Cancer
Cytoskeleton
what are the three filaments
Intermediate Filaments
Structure of Intermediate Filaments
provides eukaryotic cells the abilities to adopt a variety of…
A) intermediate filament 10 nm diameter.... B) microtubules 25 n…
Tensile, toughtest, durable
1. Subunits are fibrous protein with N - terminal globular he…
Cytoskeleton
provides eukaryotic cells the abilities to adopt a variety of…
what are the three filaments
A) intermediate filament 10 nm diameter.... B) microtubules 25 n…
Cancer
Cancer
Metastasis
Malignant cancer cells
Benign
Cells grows abnormally
Abnormal cells have invasive characteristics and spread to di…
Uncontrolled growth
Resemble normal cells, grows slowly diary not metastasize, us…
Cancer
Cells grows abnormally
Metastasis
Abnormal cells have invasive characteristics and spread to di…
174 terms
Cancer
Growth that causes tissue to increase…
Growth that causes tissue to increase…
Any new or continued cell growth not n…
The distinct and recognizable appearan…
hypertrophy
hyperplasia
neoplasia
morphology
Growth that causes tissue to increase…
hypertrophy
Growth that causes tissue to increase…
hyperplasia
61 terms
Cancer
Stage I Cancer
Stage II-III Cancer
Stage IV Cancer
Combination chemotherapy should...(4 t…
T1-2... N0... M0
T3-4... N0-3... M0
Tany... Nany... M1
Be active as a single agent... Use different mechanism... Have diff…
Stage I Cancer
T1-2... N0... M0
Stage II-III Cancer
T3-4... N0-3... M0
60 terms
Cancer
Yes or no? Cancer runs in families, it…
Cancer is a genetic disease
Over half of the cancers in this count…
Oncogenes are cancer causing genes
Yes but the cancer is not 100% certain
Yes
Yes
Yes
Yes or no? Cancer runs in families, it…
Yes but the cancer is not 100% certain
Cancer is a genetic disease
Yes
Cancer
Genetic disease
Normal cells
Cancer cells
Genes controlling cell division
damage to DNA; acquired or inherited; usually more than 1 gen…
form tissues that hold together; adhere to each other and to…
lost ability to receive inhibitory signal or need for stimula…
proto-oncogenes and tumor-suppressor genes
Genetic disease
damage to DNA; acquired or inherited; usually more than 1 gen…
Normal cells
form tissues that hold together; adhere to each other and to…
50 terms
Cancer
Proto-oncogene
Tumor Suppressor
Retinoblastoma (Rb)
E2F
Gene that promotes cell division or inhibits apoptosis. Becom…
Gene that inhibits cell division or promotes apoptosis. Becom…
Tumor Suppressor that binds and inhibits E2F
Transcription factor for S-phase genes. Needed to pass Restri…
Proto-oncogene
Gene that promotes cell division or inhibits apoptosis. Becom…
Tumor Suppressor
Gene that inhibits cell division or promotes apoptosis. Becom…
Cancer
tumor
benign
malignant
biopsy
lump of cells
non-fatal spread
fatal spread
when they take a piece of cancer cells and study them
tumor
lump of cells
benign
non-fatal spread
Cancer
Types of tumors
Cancer as micro-evolution
Malignant tumor
Benign tumor
- carcinoma (derived from epithelial cells)... - sarcoma (derive…
- somatic cells are fated to die... - cancer cells derive from a…
- uncontrolled growth... - invasion... - colonizes new territory (m…
- proliferate in defiance of normal social controls aka UNCON…
Types of tumors
- carcinoma (derived from epithelial cells)... - sarcoma (derive…
Cancer as micro-evolution
- somatic cells are fated to die... - cancer cells derive from a…
59 terms
cancer
cancer
six
carcinogen
initiator
the uncontrolled growth of abnormal cells; can affect every p…
there are __ steps to cancer formation
step 1. of cancer formation- ... exposure to a ___, a cancer-cau…
step 2. of cancer formation- ... entry of the ___ into a cell
cancer
the uncontrolled growth of abnormal cells; can affect every p…
six
there are __ steps to cancer formation
169 terms
Cancer
Childhood CA is
Most prevalent - 0-14 yr olds
Most prevalent - 15-19 yr olds
2nd leading cause of death in US child…
Rare... (15,780 new CA/year)
Leukemia - 26%... CNS - 21% ... Lymphoma - 10%
Hodgkin - 15%... Thyroid - 11%... CNS - 10%... Testicular - 8%
CA
Childhood CA is
Rare... (15,780 new CA/year)
Most prevalent - 0-14 yr olds
Leukemia - 26%... CNS - 21% ... Lymphoma - 10%
99 terms
Cancer
Neoplasm
Cancer
Benign Tumors
Carcinoma
Growth of cells or tumor which is autonomous/uncontrolled, of…
Generic name for malignant neoplasms or tumors, which are agg…
Neoplasias that don't spread/are not malignant
Epithelial malignant neoplasm
Neoplasm
Growth of cells or tumor which is autonomous/uncontrolled, of…
Cancer
Generic name for malignant neoplasms or tumors, which are agg…
25 terms
Cancer
cancer
an uncontrolled growth of cells
a genetic disease
carcinomas
-an uncontrolled growth of cells... -a genetic disease... -a family…
healthy cells turn into the enemy... -divide too quickly or abno…
-mutations in DNA can cause normal cells to become cancerous…
from cells which protect the body from air and internal fluid…
cancer
-an uncontrolled growth of cells... -a genetic disease... -a family…
an uncontrolled growth of cells
healthy cells turn into the enemy... -divide too quickly or abno…
24 terms
Cancer
Benign
Malignant
Characteristics
Angiogenesis
Remain at original site
Spread to new tissue... Metastasis
Unlimited cell division... Passed to progeny... Loss of density dep…
Formation of blood vessels
Benign
Remain at original site
Malignant
Spread to new tissue... Metastasis
101 terms
Cancer
Difference between Tumor and Cancer
What are the four cancer types?
Oncogene vs Proto-Oncogene
ERB/HER1
Cancer is a malignant tumor... Tumor is abnormal mass of maligna…
Carcinoma (in situ or invasive)- Epithelial cells... Sarcomas (r…
Proto-Oncogene- A protein that normally promotes proliferatio…
Codes for EGFR... SCC-Lung Cancer
Difference between Tumor and Cancer
Cancer is a malignant tumor... Tumor is abnormal mass of maligna…
What are the four cancer types?
Carcinoma (in situ or invasive)- Epithelial cells... Sarcomas (r…
Cancer
What is cancer?
Carcinoma
sarcoma
leukemia
A group of diseases characterized by the uncontrolled and unr…
Begins in skin of tissues that line or cover internal organs
begins in bone, cartilage, fat, muscle, blood vessels, or oth…
starts in blood-forming tissue such as bone marrow
What is cancer?
A group of diseases characterized by the uncontrolled and unr…
Carcinoma
Begins in skin of tissues that line or cover internal organs
Cancer
Cancer
Tumor
Benign
Malignant
A malignant growth or tumor caused by abnormal, uncontrolled…
Mass of cells that continue to grow and divide without any ob…
A tumor that is not cancerous.
Any tumor that is cancerous and has the potential of spreadin…
Cancer
A malignant growth or tumor caused by abnormal, uncontrolled…
Tumor
Mass of cells that continue to grow and divide without any ob…
Cancer
Cancer
Tumor
Benign Tumor
Malignant Tumor
A growth or tumor caused by uncontrolled cell division.
Mass of cells that continue to grow and divide uncontrollably
A tumor that will not spread cancer to other parts of the body.
A tumor that has the potential of spreading to other parts of…
Cancer
A growth or tumor caused by uncontrolled cell division.
Tumor
Mass of cells that continue to grow and divide uncontrollably
61 terms
Cancer
neoplasia
differentiation
anaplasia
metastasis
What is the formation or presence of a new, abnormal growth o…
What is the specialization process by which cells turn into t…
What is lack of or loss of cell differentiation (cells don't…
What is spreading of the cells to different parts of the body?
neoplasia
What is the formation or presence of a new, abnormal growth o…
differentiation
What is the specialization process by which cells turn into t…
16 terms
Cancer
Neoplasm
Benign Growth
Malignant Growth
Metastasis
Abnormal mass of dividing cells (a type of tumor)
Localized, compact growth (good) may have capsule around it
Cancer: Uncontrolled growth w/ no capsule -- Cells behave pri…
Spread of cancer throughout body
Neoplasm
Abnormal mass of dividing cells (a type of tumor)
Benign Growth
Localized, compact growth (good) may have capsule around it
Cancer
risk factor
mutation
tumor
oncogene
is any attribute, characteristic or exposure of an individual…
a error in genetic material
a swelling of a part of the body, generally without inflammat…
a gene that in certain circumstances can transform a cell int…
risk factor
is any attribute, characteristic or exposure of an individual…
mutation
a error in genetic material
34 terms
cancer
Pancytopenia
Leukopenia
Anemia
Thrombocytopenia
deficiency of all blood cells (red, white, and platelets)
deficiency of white cells
hemoglobin of 6 or 7
platelets- Bleeding
Pancytopenia
deficiency of all blood cells (red, white, and platelets)
Leukopenia
deficiency of white cells
16 terms
Cancer
cancer
mutation
tumor
surgery
disease in which some body cells grow and divide uncontrollab…
change in a gene or chromosome
mass of abnormal cells that develops when cancerous cells div…
treatment where tumor and surrounding cells are removed
cancer
disease in which some body cells grow and divide uncontrollab…
mutation
change in a gene or chromosome
30 terms
Cancer
Cancer behaviors
Carcinomas
Sarcomas
Lymphomaa
Continue to reproduce... Ignore cell signals for contact inhibit…
Endodermal or ectodermal, epithelial lining of organs and gla…
Mesodermal connective tissue... Sarcoma refers to cancer that o…
Lymphoid tissue... Lymphomas develop in the glands or nodes of t…
Cancer behaviors
Continue to reproduce... Ignore cell signals for contact inhibit…
Carcinomas
Endodermal or ectodermal, epithelial lining of organs and gla…
47 terms
Cancer
cancer
benign
malignant
metastasis
malignant neoplasm marked by uncontrolled growth of cells ... -…
over growth of normal tissues that do not cause risk to patie…
-a mass of cancer cells that may invade surrounding tissues o…
movement of cancer cells from primary sit to another part... -c…
cancer
malignant neoplasm marked by uncontrolled growth of cells ... -…
benign
over growth of normal tissues that do not cause risk to patie…
Cancer
to reduce the risk
to impact smth
to contribute to smth
to do research
to diminish the risk
to influence smth
to add to smth
to analyse
to reduce the risk
to diminish the risk
to impact smth
to influence smth
49 terms
Cancer
Two major dysfunctions present in the…
cancer cells divide indiscriminately a…
Through differentiation__
Protooncogenes are__
:(1) defective cellular proliferation (growth) and (2) defect…
__produce more than two cells at the time of mitosis.
__cells become capable of performing only specific functions.
__normal cellular genes that are important regulators of norm…
Two major dysfunctions present in the…
:(1) defective cellular proliferation (growth) and (2) defect…
cancer cells divide indiscriminately a…
__produce more than two cells at the time of mitosis.
Cancer
2 major problems with chemotherapy
Angiogenesis
Angiostatin
How did Dr. Folkman believe cancerous…
Poisonous chemicals... Symptoms
New blood vessel growth
Stop blood vessel growth
A tumor couldn't grow without blood supply, so cut off the bl…
2 major problems with chemotherapy
Poisonous chemicals... Symptoms
Angiogenesis
New blood vessel growth
122 terms
Cancer
Most common cancer for male
Most common cancer for female
most common for both
What is equilibrium of cells
prostate
breast
colon cancer
ability to regenerate at an equal rate of death of cells
Most common cancer for male
prostate
Most common cancer for female
breast
Cancer
Incidence of lung, colorectal, and ora…
Non-hodgkin's lymphoma and skin cancer…
Which cancer is rising faster than any…
Cancer is high in what gender and ethn…
decreased
Increased
Melanoma
Men and African Americans
Incidence of lung, colorectal, and ora…
decreased
Non-hodgkin's lymphoma and skin cancer…
Increased
15 terms
cancer
carcinoma
sarcoma
myeloma
leukemia
skin or internal organ lining
connective tissue ( bone muscle blood vessels)
plasma cells of bone marrow
blood/ bone marrow
carcinoma
skin or internal organ lining
sarcoma
connective tissue ( bone muscle blood vessels)
44 terms
Cancer
Colo-rectal cancer
Breast Cancer
Lung Cancer
Epigenetics
- there are 2 types
...
...
-stress triggers a gene that was inherited to express itself…
Colo-rectal cancer
- there are 2 types
Breast Cancer
...
35 terms
Cancer
Neoplasm
Hyperplastic
Metaplastic
Dysplastic
-TUMOR... abnormal tissue mass, ... -uncontrolled growth:... which exc…
tissue or organ is larger due to excessive numbers of cells
-PRECANCEROUS... one type of normal cell layer is displaced by a…
cells appear abnormal in cytological screen
Neoplasm
-TUMOR... abnormal tissue mass, ... -uncontrolled growth:... which exc…
Hyperplastic
tissue or organ is larger due to excessive numbers of cells
Cancer
cancer
tumor
carcinogen
lifestyle factors
a group of over 100 diseases that disrupts the cell cycle and…
a mass of cancer cells
any substance that is known to cause cancer
activities or choices that will affect your health
cancer
a group of over 100 diseases that disrupts the cell cycle and…
tumor
a mass of cancer cells
98 terms
Cancer
Oncogene
Growth factors
Growth factor receptors
G proteins
Mutant versions of proto-oncogenes that function without a re…
Platelet derived growth factor ... Insulin like growht factor ... p…
human epideral growth factor 2 ... ERBB2
RAS (30% of all cancers, half of all colon)
Oncogene
Mutant versions of proto-oncogenes that function without a re…
Growth factors
Platelet derived growth factor ... Insulin like growht factor ... p…
9 terms
Cancer
t(15,17) translation mutation
t(9,22)
CD19 and CD3
T315I
APL... -ATRA targets specifically for apoptosis
Ph(+)... -poor prognosis... -ALL, CML
BiTE... Blinatumomab - ALL
BCR-ABL dependent: mutation in TK binding domain... -beware resi…
t(15,17) translation mutation
APL... -ATRA targets specifically for apoptosis
t(9,22)
Ph(+)... -poor prognosis... -ALL, CML
Cancer
Describe Cancer:
Metastasis
3 Routes of metastasis:
Cancer classification:
Cancer is a neoplastic disorder that can involve all body org…
cancer cells move from their original location to other sites
local seeding - distribution of shed cancer cells occurs in t…
Solid tumors: associated with the organs from which they deve…
Describe Cancer:
Cancer is a neoplastic disorder that can involve all body org…
Metastasis
cancer cells move from their original location to other sites
Cancer
What is cancer?
Carcinoma
sarcoma
leukemia
A group of diseases characterized by the uncontrolled and unr…
Begins in skin of tissues that line or cover internal organs
begins in bone, cartilage, fat, muscle, blood vessels, or oth…
starts in blood-forming tissue such as bone marrow
What is cancer?
A group of diseases characterized by the uncontrolled and unr…
Carcinoma
Begins in skin of tissues that line or cover internal organs
25 terms
Cancer
Cancer
HPV
Tumor
Malignant
A disease in which some body cells grow and divide uncontroll…
human papilloma virus
Cells that divide in to a clusters of tissue.
Cancerous...to cause harm
Cancer
A disease in which some body cells grow and divide uncontroll…
HPV
human papilloma virus
68 terms
Cancer
Cancer
Mitosis
5 Kinds of Regular Mitosis
Angiogenesis
unrestrained cell growth; abnormal cell division
cell division resulting in 2 identical daughter cells
Repair- same cell replacement to damaged tissue... Replacement-…
Growth of capillaries (to bypass an occlusion)
Cancer
unrestrained cell growth; abnormal cell division
Mitosis
cell division resulting in 2 identical daughter cells
15 terms
Cancer
Angiogenesis
Metastasis
Mitosis
Etiology of cancer
Chemical signal sent by cell to recieve blood supply.
Migration of cancerous cells
signal sent to start cell division. (does not apply to cancer…
changes to DNA = altered genes = mutated cell/tumor (benign o…
Angiogenesis
Chemical signal sent by cell to recieve blood supply.
Metastasis
Migration of cancerous cells
31 terms
Cancer
steps in carcinogenesis
Hallmarks of cancer
Cell growth autonomy
Evasion of growth inhibitory signals
Intitiaton ... Promotion... Progression
-Evasion of apoptosis... -Growth signal autonomy... -evasion of gro…
cancer cells not dependent on normal growth factor signaling…
acquired mutations of gene silencing disrupt stop signaling t…
steps in carcinogenesis
Intitiaton ... Promotion... Progression
Hallmarks of cancer
-Evasion of apoptosis... -Growth signal autonomy... -evasion of gro…
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