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Study sets matching "cardiophys"

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Study sets matching "cardiophys"

37 terms
Cardiophys
arteries
capillaries
veins
capillary walls
elastic, muscular, arterioles
site of exchange with tissues
thinner walls than arteries, contain less elastic tissue and…
consists of endothelial cells (simple squamous epithelium), b…
arteries
elastic, muscular, arterioles
capillaries
site of exchange with tissues
58 terms
cardiophys
Increased sympathetic activation of my…
Mean aortic pressure (MAP)... a. Is the t…
the percentage of a fixed cardiac outp…
Which of the following is a true state…
A. Positive dromotropic... - increased rate of AV node stimulat…
D. ... MAP = SV X HR X TPR... Mean arterial pressure = Stroke volum…
D. ... Organ relative vascular resistance... - organs with higher…
D. ... - system pressure is higher than pulmonary because syste…
Increased sympathetic activation of my…
A. Positive dromotropic... - increased rate of AV node stimulat…
Mean aortic pressure (MAP)... a. Is the t…
D. ... MAP = SV X HR X TPR... Mean arterial pressure = Stroke volum…
14 terms
Cardiophys 3B
What drives filtration?
Starlings equation
Arterial side vs veinous side
How does body account for net outwards…
-hydrostatic pressure ... -leak of fluid from capillaires ... -capi…
-tells us that filtration is driven by pressure difference ba…
-arterial side its going out, venous coming back in ... -overall…
-lymphatic system
What drives filtration?
-hydrostatic pressure ... -leak of fluid from capillaires ... -capi…
Starlings equation
-tells us that filtration is driven by pressure difference ba…
15 terms
Cardiophys Hormones/Chemicals
Renin
Angiotensinogen
ACE
Angiotensin II
Secreted from juxtaglomerular cells in Kidney. Acts to conver…
Secreted by the liver constantly. Converted to angiotensin I…
Turns angiotensin I to II. From vascular epithelial cells and…
Causes aldosterone secretion, vasoconstriction, and Na resorp…
Renin
Secreted from juxtaglomerular cells in Kidney. Acts to conver…
Angiotensinogen
Secreted by the liver constantly. Converted to angiotensin I…
18 terms
Pharm-6-Cardiophys
What are the phase of a cardiac action…
in phase 0 of the cardiac action poten…
in phase 1 of the cardiac action poten…
What is responsible for the plateau in…
phase 0 upstroke; rapid depolarization... phase 1 early fast…
in phase 0 of the cardiac action potential, fast Na+ channe…
in phase 1 of the cardiac action potential, fast Na+ channe…
balance b/t... - Ca2+ influx (via L-type Ca2+ channels) ... - K+…
What are the phase of a cardiac action…
phase 0 upstroke; rapid depolarization... phase 1 early fast…
in phase 0 of the cardiac action poten…
in phase 0 of the cardiac action potential, fast Na+ channe…
114 terms
BIO331 - Exam #2, Blood & Cardiophys
98.6F, 37C
75 bpm
38C
Females: 4-5L; Males: 5-6L
Normal Values: Body Temp
Normal Values: Pulse
Normal Values: Blood Temp
Normal Values: Blood Volume
98.6F, 37C
Normal Values: Body Temp
75 bpm
Normal Values: Pulse
32 terms
human phys test 3 endocrine and cardiophys
The pituitary gland lies in a pocket o…
The pituitary gland has two lobes: the…
The anterior pituitary gland secretes…
Follicular stimulating hormone (FSH) a…
infundibulum
smooth muscle contractions such as labor or lactation or bloo…
secretion of other hormones from other organs.
secreted by anterior pituitary onto gonads for germ cell deve…
The pituitary gland lies in a pocket o…
infundibulum
The pituitary gland has two lobes: the…
smooth muscle contractions such as labor or lactation or bloo…
9 terms
Exam 3 Anatomy Lab: Respiration/Cardiophys
Expiratory Reserve Volume (ERV)
Expiratory Capacity
Tidal Volume
Inspiratory Reserve Volume (IRV)
max volume of air that can be forcefully exhaled after a norm…
the max volume of air that can be forcefully exhaled after a…
the amount of air that moves in (or out of) the lungs during…
the volume of air that can be forcefully inhaled after a norm…
Expiratory Reserve Volume (ERV)
max volume of air that can be forcefully exhaled after a norm…
Expiratory Capacity
the max volume of air that can be forcefully exhaled after a…
75 terms
A&P LAB EXAM 3 (cardiophys, resp, dig, urinary)
What cardiac structure ensures one way…
list layers of the heart wall from sup…
which pericardial layer produces peric…
what fixes the heart in place and prev…
valves
epicardium, myocardium, endocardium
visceral pericardium
pericardium
What cardiac structure ensures one way…
valves
list layers of the heart wall from sup…
epicardium, myocardium, endocardium
15 terms
Cerebral Circulation
main function of cerebral function
circle of willis function
capillary density of cerebrum
BBB function
maintain oxygen and glucose to hypoxia intolerant grey matter
anatomical guard against ischemia
high - small diffusion distance
provides a stable neuronal environment
main function of cerebral function
maintain oxygen and glucose to hypoxia intolerant grey matter
circle of willis function
anatomical guard against ischemia
122 terms
JUMC Physiology Midterm #3 (PRETEST)
E
C
D
B
During which interval on the EKG does the aortic valve close?
In a test subject, oxygen consumption was measured at 700 mL/…
Which one of the following is the best index of preload?... a. B…
Which one of the following is the best index of afterload?... a.…
E
During which interval on the EKG does the aortic valve close?
C
In a test subject, oxygen consumption was measured at 700 mL/…
13 terms
Coronary Circulation
most of coronary arterial BF happens d…
flow pattern is due to
flow out into veins occurs during
myocardial O2 extraction
diastole
systolic compression of arteriolar vessels within myocardium
systole as myocardial focres squees blood into vein
very high
most of coronary arterial BF happens d…
diastole
flow pattern is due to
systolic compression of arteriolar vessels within myocardium
17 terms
Cutaneous Circulation
vessels in epidermis
skin blood flow function
skin and subQ are
how heat gets out of body
none
regulate internal temperature
insulators
radiated out... evaporation... conduct-convect
vessels in epidermis
none
skin blood flow function
regulate internal temperature
23 terms
Fetal Circulation
placenta acts as a
blood from mom comes to fetus via
umbilical vein blood goes to
ductus venosus
parallel organ that provides vascular shunt on mom
umbilical vein
IVC
opening that takes umbilical vein and liver blood to IVC
placenta acts as a
parallel organ that provides vascular shunt on mom
blood from mom comes to fetus via
umbilical vein
49 terms
Microcirculation
gas exchange occurs via
fluid exchange via
fluid exchange primarily occurs through
protein passes through
diffusion through wall via fick's law
convection through, small and large pores
aquaporin channels
large pores
gas exchange occurs via
diffusion through wall via fick's law
fluid exchange via
convection through, small and large pores
74 terms
Cardiovascular Controls
vasomotor center location
HR determined by
SV depends on
for fixed BV, ABP/MAP depends on
medullary CV control centers
interplay between sympathetic and vagal activity
SNS alterations of Ca availability changing contractility... pre…
CO... TPR
vasomotor center location
medullary CV control centers
HR determined by
interplay between sympathetic and vagal activity
30 terms
Electromechanical Activity
action potential leads to opening of
calcium entering myocytes will lead to
afterload
preload
voltage gated L type calcium channel
calcium induced calcium release from SR
load contracting muscle works against
initial stretch as muscle starts to contract
action potential leads to opening of
voltage gated L type calcium channel
calcium entering myocytes will lead to
calcium induced calcium release from SR
58 terms
Hemodynamics
PV loop
loop width indicates
stroke work
stroke work found by
view cardiac cycle in terms of volume and pressure
SV
work done by heart per beat
area of PV loop
PV loop
view cardiac cycle in terms of volume and pressure
loop width indicates
SV
57 terms
Oxygen Exchange & Venous System
amount of oxygen per 100mL of blood at…
after blood passes through systemic ci…
amount of oxygen released at periphery
O2 extraction/utilization
20mL of oxygen
75% - 15mL of oxygen per 100mL of blood
5mL per 100mL of blood
amount of O2 used
amount of oxygen per 100mL of blood at…
20mL of oxygen
after blood passes through systemic ci…
75% - 15mL of oxygen per 100mL of blood
116 terms
Arterial Pulse Propagation & Reflection
acute causes of heart failure (3)
chronic causes of heart failure (3)
pressure/volume overload occurs due to…
increased afterload produced by
MI... infection... post bypass surgery
pressure/volume overload... adaptive remodeling... functional decline
increased afterload... aortic regurgitation
HTN... aortic stenosis
acute causes of heart failure (3)
MI... infection... post bypass surgery
chronic causes of heart failure (3)
pressure/volume overload... adaptive remodeling... functional decline
111 terms
Peripheral Vascular Control
shear stress causes endothelial cell i…
NO from EC causes
NE binds to alpha receptors to cause
EPI binds
NO
flow induced vasodilation
vasoconstriction
alpha receptors... B2 receptors (preferentially)
shear stress causes endothelial cell i…
NO
NO from EC causes
flow induced vasodilation
24 terms
CV Coupling
compliance of veins is found by
if TPR is very large compared to Ra an…
Pressure in veins found by
when heart is stopped Pv found by
adding compliance of peripheral and central veins
can neglect both Ra and Rv
Pa - QR
Pa - R
compliance of veins is found by
adding compliance of peripheral and central veins
if TPR is very large compared to Ra an…
can neglect both Ra and Rv
48 terms
Cardiac Cycle
increased contractility effect on card…
drugs used to increase contractility c…
changes in Ca entry and storage can be…
cardiac glycoside increases contractil…
increases slope of PIP line -> greater SV
positive inotropic agents
SNS activity on heart... changes in levels of circulating catech…
inhibiting Na/K pump which decreases EC Na levels which decre…
increased contractility effect on card…
increases slope of PIP line -> greater SV
drugs used to increase contractility c…
positive inotropic agents
6 terms
CardioPhys Exam 3
fenestrated capillaries
diffusion capillaries
Q = K T x 'P FILT
Lymphedema = Edema + Protein
Kidney glomeruli •Intestinal mucosa •Endocrine Glands
•Bone Marrow •Spleen •Liver
...
...
fenestrated capillaries
Kidney glomeruli •Intestinal mucosa •Endocrine Glands
diffusion capillaries
•Bone Marrow •Spleen •Liver
13 terms
CardioPhys 1
ventricular systolic pressure
driving pressure (delta P)
Q... coefficient of proportionality
systole
pressure that occurs at peak ventricular contraction as blood…
P1-P= potential energy gradient
(P1-P1)/R
ventricular contraction... A-V valves closed
ventricular systolic pressure
pressure that occurs at peak ventricular contraction as blood…
driving pressure (delta P)
P1-P= potential energy gradient
15 terms
CV Introduction, CO/SV, Blood Pressure
What areas of the heart are supplied b…
What areas of the heart are supplied b…
What is SVR?
What is PVR?
Right ventricle... Inferior surfaces... Septum
Splits into the...... LAD --> RBB, LBB, Septum, Anterior Surface…
Systemic Vascular Resistance ... SVR = (MAP-R. Atrial P)/CO... *Cha…
Pulmonary Vascular Resistance... PVR = (MPAP - L. Atrial P)/CO... *…
What areas of the heart are supplied b…
Right ventricle... Inferior surfaces... Septum
What areas of the heart are supplied b…
Splits into the...... LAD --> RBB, LBB, Septum, Anterior Surface…
28 terms
CardioPhys 1
Determine Pc
turbulence loses _____
Large Arteries energy is _____
Laplaces Law
ratio RA/RV higher ratio, smaller Pc
energy
Loseless
Tension = tramural pressure radius/ wall thicknesss
Determine Pc
ratio RA/RV higher ratio, smaller Pc
turbulence loses _____
energy
20 terms
Vascular Resistance, ANS Control, Cardiac Output, Blood Flow/Velocity
How does blood flow lose energy?
What is TPR?
What is PVR?
What is the SVR of the following condi…
Due to friction with the vessel. Kinetic energy is transferre…
Total Peripheral Resistance / Systemic Vascular Resistance. T…
Pulmonary Vascular Resistance... PVR = MPAP-PCWP / CO... Mean pulmo…
SVR = (110-10)/6 ... SVR = 100/6 mmHg /(L/min)
How does blood flow lose energy?
Due to friction with the vessel. Kinetic energy is transferre…
What is TPR?
Total Peripheral Resistance / Systemic Vascular Resistance. T…
CardioPhys 1
Right coronary artery supplies
Anterior descending artery supplies
Circumflex artery supplies
Flow of blood
SA node... AV node... Right ventricle... septum... inferior surfaces... main…
Left bundle branch... Right bundle branch... Septum
posterior wall... lateral wall
RA -> TV -> RV -> PV -> lung -> LA -> MV -> LV -> AV -> organ…
Right coronary artery supplies
SA node... AV node... Right ventricle... septum... inferior surfaces... main…
Anterior descending artery supplies
Left bundle branch... Right bundle branch... Septum
CardioPhys Final
Contraction initiation due to calcium
Contraction termination
Phospholamban
Ectopic excitation
1. Electrical activity -> SA node -> ventricles via electrica…
Elevated sarcoplasmic Ca++ increases Ca++ pump and ion transp…
reuptake inhibitory protein... controls Ca-ATPase pump... To incre…
SR [Ca++] is not restored to pre-systolic levels... Excitation c…
Contraction initiation due to calcium
1. Electrical activity -> SA node -> ventricles via electrica…
Contraction termination
Elevated sarcoplasmic Ca++ increases Ca++ pump and ion transp…
151 terms
CardioPhys Exam1
Does the parasympathetic nervous syste…
What is the blood that gets back to th…
What is the hydraulic resistance equat…
What is the definition of resistance a…
no
the peripheral vascular system
P = Flow x Resistance... MAP = Q X TPR... Change in P = Q X R
How "difficult" it is to move blood through the cardiovascula…
Does the parasympathetic nervous syste…
no
What is the blood that gets back to th…
the peripheral vascular system
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