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Study sets matching "diabetes insulin"

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Study sets matching "diabetes insulin"

Diabetes Insulin
Rapid-acting Insulin
Short-acting Insulin... *Regular
Intermediate-acting Insulin
Long-acting
Onset: 10 minutes... Peak: 1 to 3 hours... Duration: 3 to 5 hours
Onset: 30 minutes... Peak: 2.5 to 5 hours... Duration: 5 to 10 hours
Onset: 4 hours... Peak: 4 to 12 hours... Duration: 16 to 24 hours
Onset: 1 hour... No peak... Duration: 24 hours
Rapid-acting Insulin
Onset: 10 minutes... Peak: 1 to 3 hours... Duration: 3 to 5 hours
Short-acting Insulin... *Regular
Onset: 30 minutes... Peak: 2.5 to 5 hours... Duration: 5 to 10 hours
31 terms
Insulin + Diabetes
Biosynthesis & Post-translational proc…
Description of primary & secondary str…
Description of tertiary structure of i…
Description of quaternary structure of…
1) Preproinsulin translated by ribosomes... 2) Signal sequence c…
1°= AA sequences... 2°= α helices + β chains... -α helix: Gly1, Gl…
3°= folding of 2° structures into monomer... -AA form a moderat…
4°= arranging 3° structures into multi-subunit complexes ... -D…
Biosynthesis & Post-translational proc…
1) Preproinsulin translated by ribosomes... 2) Signal sequence c…
Description of primary & secondary str…
1°= AA sequences... 2°= α helices + β chains... -α helix: Gly1, Gl…
27 terms
Insulin and Diabetes
Islets of Langerhans
Pancreatic cell mass
Size/number
Innervation
embedded in exocrine acinar tissue
2% of total
0.2µm, ~3000 cells, size preserved across species, number dif…
Symp- adr... Parasymp-cholinergic and adrenergic on muscarinic r…
Islets of Langerhans
embedded in exocrine acinar tissue
Pancreatic cell mass
2% of total
8 terms
Diabetes insulin
Rapid acting - Lispro (Humalog )
Short Acting -Regular insulin Novolin R
Long acting- Insulin glargine (Lantus)
Rapid acting
more rapid onset <15. Given 15 minutes before a meal. ... Much l…
Used to treat DKA, to initiate treatment for newly diagnosed…
is a 24 hour, long acting rDNA Human insulin analog that is g…
name onset Peak Duration ... Lispro Humalog 0.25 1-1.5 hr 3-4... As…
Rapid acting - Lispro (Humalog )
more rapid onset <15. Given 15 minutes before a meal. ... Much l…
Short Acting -Regular insulin Novolin R
Used to treat DKA, to initiate treatment for newly diagnosed…
26 terms
DIABETES (INSULIN)
RAPID-ACTING: LISPRO (ONSET)
RAPID-ACTING: LISPRO (PEAK)
RAPID-ACTING: LISPRO (DURATION)
SHORT-ACTING: REGULAR (ONSET)
15 MINUTES
60-90 MINUTES
3-4 HOURS
30 MINUTES-1 HOUR
RAPID-ACTING: LISPRO (ONSET)
15 MINUTES
RAPID-ACTING: LISPRO (PEAK)
60-90 MINUTES
54 terms
Insulin and Diabetes
Acini
Islet of Langerhans
Alpha Cell
Beta Cell
exocrine glands that secrete digestive juices
secrete hormones into the blood
glucogan
Insulin
Acini
exocrine glands that secrete digestive juices
Islet of Langerhans
secrete hormones into the blood
46 terms
Diabetes and Insulin
If a patient has been ordered insulin,…
(True or False) Insulin Glargine (Lant…
When you cannot find an insulin syring…
Insulin Lispro (Humalog) is ______ -ac…
b. no, never administer insulin when patient's BG is less tha…
False, the long acting insulins such as Insulin Glargine (Lan…
No
rapid
If a patient has been ordered insulin,…
b. no, never administer insulin when patient's BG is less tha…
(True or False) Insulin Glargine (Lant…
False, the long acting insulins such as Insulin Glargine (Lan…
11 terms
Diabetes Insulin
Rapid acting
Short acting
Intermediate acting
Long acting
Lispro, aspart, glulisine
Humulin R, Novolin R
NPH ( Humulin N, Novolin N)
Determir, Lantus
Rapid acting
Lispro, aspart, glulisine
Short acting
Humulin R, Novolin R
8 terms
Diabetes: Insulin
Lispro
Aspart
Glulisine
Inhaled Insulin
HUMALOG
NOVOLOG
APIDRA
AFREZZA
Lispro
HUMALOG
Aspart
NOVOLOG
8 terms
Diabetes/ Insulin
Byetta
Amaril
Glucotrol
Diabeta
Exenatide
Glimepiride
Glipizide
Glyburide
Byetta
Exenatide
Amaril
Glimepiride
13 terms
Diabetes - Insulin
Insulin MOA
Rapid Acting Insulin Agents
Rapid Acting Insulin dosing
Rapid Acting Insulin warnings
Mediates uptake of glucose by muscles and adipose tissue
Aspart (NovoLOG and NovoLOG Flexion)... Glulisine (Apidra, Apidr…
100 units/ml... (Kwikpen comes as 200 units/ml - use when patien…
Hypoglycemia... Hypokalemia... Renal/hepatic impairment - use caution
Insulin MOA
Mediates uptake of glucose by muscles and adipose tissue
Rapid Acting Insulin Agents
Aspart (NovoLOG and NovoLOG Flexion)... Glulisine (Apidra, Apidr…
16 terms
Diabetes & Insulin
Rapid Acting Insulin brands
Short Acting Insulin brands
Intermediate acting brands
Long Acting Insulin brands
Lispro, Aspart, Glusuline
Regular
NPH
Glargiline
Rapid Acting Insulin brands
Lispro, Aspart, Glusuline
Short Acting Insulin brands
Regular
36 terms
Diabetes - Insulin
insulin lispro
insulin aspart
insulin glulisine
regular insulin
Humalog
NovoLog
Apidra
Humulin R (Eli Lily)... Novolin R (Norvo Nordisk)
insulin lispro
Humalog
insulin aspart
NovoLog
36 terms
Insulin, Diabetes
Rapid-Acting Insulins
Short-Acting Insulins, aka Regular
Intermediate-Acting Insulins
Long-Acting Insulins
Humalog... Novalog... Apidra... Onset: 15 minutes... Duration: 3-5 hours…
Humulin R (Regular)... Novolin R (Regular)... Onset: 30 minutes... Du…
Humulin N (NPH)... Novolin N (NPH)... Onset: 1-1.5 hours... Duration:…
Lantus... Levemir... Onset: 1 hour... Duration: 24 hours... Mixing: NO M…
Rapid-Acting Insulins
Humalog... Novalog... Apidra... Onset: 15 minutes... Duration: 3-5 hours…
Short-Acting Insulins, aka Regular
Humulin R (Regular)... Novolin R (Regular)... Onset: 30 minutes... Du…
12 terms
Diabetes Insulin
Humalog Onset
Humalog peak
Humalog duration
humulin R Onset
10-30 mins
.5-3 hours
3-5 hours
30-60 mins
Humalog Onset
10-30 mins
Humalog peak
.5-3 hours
37 terms
Diabetes-insulin
Insulin uses
Ultra-short acting insulin
Short-acting insulin
Intermediate
-Type 1 and type 2 diabetes ... -High fasting glucose levels > 2…
- similar to the way natural actual insulin works ... -Aspart, L…
more affordable bc been around longer... -Regular: onset 30-60 m…
NPH- onset 2-4 hours, peak 4-8 hrs, duration 8-12 hrs
Insulin uses
-Type 1 and type 2 diabetes ... -High fasting glucose levels > 2…
Ultra-short acting insulin
- similar to the way natural actual insulin works ... -Aspart, L…
22 terms
Diabetes/ Insulin
Works in the Pancreas
Works in Liver & Cells
Works in Pancreas & Liver
Works in small intestine
Glipizide, Glyburide, Starlix
Metformin
Januvia
Precose
Works in the Pancreas
Glipizide, Glyburide, Starlix
Works in Liver & Cells
Metformin
9 terms
Insulin(diabetes)
Lantus
Humalog
Novolog
Levemir
Insulin glargine
Insulin lispro
Insulin aspart
Insulin detemir
Lantus
Insulin glargine
Humalog
Insulin lispro
18 terms
Diabetes/insulin
Byetta
Amaryl
Glucotrol,
Glucotrol xl
Exenatide
Glimepiride
Glipizide
Glipizide
Byetta
Exenatide
Amaryl
Glimepiride
18 terms
Diabetes/Insulin
Byetta
Amaryl
Glucotrol
Diabeta, Micronase, Glynase
Exenatide
Glimeperide
Glipizide
Glyburide
Byetta
Exenatide
Amaryl
Glimeperide
9 terms
Diabetes:/ insulin
Actos
Avandia
Janumet
Lantus
Pioglitazone
Rosiglitazone
Metformin/ sitagliptin
Insulin glargine
Actos
Pioglitazone
Avandia
Rosiglitazone
25 terms
Diabetes/Insulin
Insulin Lispro (humalog)
Rapid acting insulin
Insulin aspart (NovoLog)
Insulin glulisine (Apidra)
Onset; 10-30 min ... Peak; 30min-3hr ... Duration; 3-5hr
Insulin Lispro (humalog)... &... Insulin aspart (NovoLog)... &... Insulin…
Onset; 10-30 min ... Peak; 30min-3hr ... Duration; 3-5hr
Onset; 10-30 min ... Peak; 30min-3hr ... Duration; 3-5hr
Insulin Lispro (humalog)
Onset; 10-30 min ... Peak; 30min-3hr ... Duration; 3-5hr
Rapid acting insulin
Insulin Lispro (humalog)... &... Insulin aspart (NovoLog)... &... Insulin…
12 terms
Diabetes/Insulin
Byetta
Amaryl
Glucotrol
Diabeta, Micronase, Glynase
Exenatide
Glimepiride
Glipizide
Glyburide
Byetta
Exenatide
Amaryl
Glimepiride
17 terms
Diabetes Insulin
rapid acting insulin
rapid acting onset of action
rapid acting peak action
rapid acting effective duration
lispro... aspart... glulisine
5-15 min
30-90 min
3-5 hr
rapid acting insulin
lispro... aspart... glulisine
rapid acting onset of action
5-15 min
16 terms
Diabetes/Insulin
Byetta
Amaryl
Glucotrol
Glucotrol XL
Exenatide
Glimepiride
Glipizide
Glipizide
Byetta
Exenatide
Amaryl
Glimepiride
12 terms
Diabetes/Insulin
Rapid-acting insulin
Short-acting insulin
Intermediate-acting insulin
Extended long-acting insulin
Clear, bolus, prandial... Ex: Lispro (Humalog)... Onset: 10-15 min…
aka "fast-acting"... Clear, bolus, prandial... Ex: regular (Humulin…
Cloudy, basal... Ex: NPH (Humulin N)... Onset: 1-3 hr... Peak: 6-8 hr…
Clear, basal... Ex: Glargine (Lantus)... Onset: 1-2 hr... Peak: relati…
Rapid-acting insulin
Clear, bolus, prandial... Ex: Lispro (Humalog)... Onset: 10-15 min…
Short-acting insulin
aka "fast-acting"... Clear, bolus, prandial... Ex: regular (Humulin…
46 terms
diabetes insulin
Rapid are Lispro,Aspart, Glulisine--15…
LAG IS RAPID
REGULAR HUMULIN IS short not rapid 30…
intermediate NPH, DETENIR, 70/30 1.5 H…
aka : Humolog, novolog, apidra
RAG IS HNA
HumulinR, novolinR
NPH IS HUMU/ NOVO, DETENIR IS LEVENIR, 70/30 IS HUMU OR NOVO
Rapid are Lispro,Aspart, Glulisine--15…
aka : Humolog, novolog, apidra
LAG IS RAPID
RAG IS HNA
43 terms
Diabetes & insulin
What organ is insulin produced in ?
What cells produce insulin ?
Purpose of insulin
Hyperglycemia
Pancreas
Beta cells
To open cells to allow nutrients in to metabolize
High blood sugar
What organ is insulin produced in ?
Pancreas
What cells produce insulin ?
Beta cells
12 terms
Diabetes-Insulin
Insulin aspart
Insulin lispro
Insulin glulisine
Insulin regular
(Novolog) Rapid-Acting
(Humalog) Rapid-Acting
(Apidra) Rapid-Acting
(Novolin R, Humulin R) Short
Insulin aspart
(Novolog) Rapid-Acting
Insulin lispro
(Humalog) Rapid-Acting
43 terms
Insulin -diabetes
HbA1c
type 1 is a ___ disease where you loose
what are stimulants of insulin release:
what are amplifiers of insulin release
hemoglobin measured... normal (non-diabetic: 6%)... target 7% or b…
wasting ... -loose: glycogen, fat, muscle ... -excretion of glucose…
glucose, mannose... leucine... vagal stimualtion ... sulfonyl ureas
enteric hormones: cholecystokinin, secretin, gastrin... beta adr…
HbA1c
hemoglobin measured... normal (non-diabetic: 6%)... target 7% or b…
type 1 is a ___ disease where you loose
wasting ... -loose: glycogen, fat, muscle ... -excretion of glucose…
22 terms
Diabetes/ Insulin
Works in the Pancreas
Works in Liver & Cells
Works in Pancreas & Liver
Works in small intestine
Glipizide, Glyburide, Starlix
Metformin
Januvia
Precose
Works in the Pancreas
Glipizide, Glyburide, Starlix
Works in Liver & Cells
Metformin
13 terms
Diabetes - Insulin and Insulin Guidelines
Insulins
NovoLOG... NovoLOG FlexPen... (rapid)
Apidra... Apidra SoloStar... (rapid)
HumaLOG... HumaLOG KwikPen... (rapid)
MoA:... SE: hypoglycemia, hypokalemia
Insulin ASPART... - Usual maint. dose: 0.5 to 1 units/kg/day... -
Insulin GLULISINE... - Usual maint. dose:
insulin LISPRO... -
Insulins
MoA:... SE: hypoglycemia, hypokalemia
NovoLOG... NovoLOG FlexPen... (rapid)
Insulin ASPART... - Usual maint. dose: 0.5 to 1 units/kg/day... -
11 terms
DIABETES/INSULIN
BYETTA
AMARYL
GLUCOTROL, GLUCOTROL XL
JANUVIA
EXENATIDE (DIABETES/ INSULIN)
GLIMEPIRIDE (DIABETES/ INSULIN)
GLIPIZIDE (DIABETES/INSULIN)
SITAGLIPTIN (DIABETES/ INSULIN)
BYETTA
EXENATIDE (DIABETES/ INSULIN)
AMARYL
GLIMEPIRIDE (DIABETES/ INSULIN)
34 terms
Diabetes - INSULIN
What was the very first attempt to pro…
What is a PZI complex?
What does NPH stand for?
When is the peak period of NPH after a…
Developing insulin products with protamine.... PROTAMINE is a b…
Protamine-zinc-insulin complex. This complex has isoelectric…
Neutral Protamine Hagedorn Insulin also called isophane. Deve…
6 to 12 hours.
What was the very first attempt to pro…
Developing insulin products with protamine.... PROTAMINE is a b…
What is a PZI complex?
Protamine-zinc-insulin complex. This complex has isoelectric…
37 terms
Diabetes - Insulin
"Ideal Insulin Characteristics"
Rapid-Acting Insulins: (name 3)
Rapid-Acting Insulins - Onset
Short-Acting Insulin: (name 1)
Basal:... - 24 hour effect... - No peak... - Consistent, reproducible…
Insulin aspart, Novolog... Insulin glulisine, Apidra... Insulin lis…
Fastest onset of action within 5-15 minutes. It is important…
Regular Insulin... (Humulin R, Novolin R)
"Ideal Insulin Characteristics"
Basal:... - 24 hour effect... - No peak... - Consistent, reproducible…
Rapid-Acting Insulins: (name 3)
Insulin aspart, Novolog... Insulin glulisine, Apidra... Insulin lis…
69 terms
Diabetes & Insulin
What do Alpha, Beta & Delta cells in t…
Which glucose transporters are in the…
Beta cells become polarized or depolar…
What blood glucose levels stimulate in…
Alpha cells: Glucagon; increase blood glucose levels; opposes…
GLUT 1 & GLUT 3: all mammalian tissues... GLUT 2: Liver and Panc…
GLUT 2 becomes depolarized. ATP/K channel is closed so ATP an…
>100 mg/dl
What do Alpha, Beta & Delta cells in t…
Alpha cells: Glucagon; increase blood glucose levels; opposes…
Which glucose transporters are in the…
GLUT 1 & GLUT 3: all mammalian tissues... GLUT 2: Liver and Panc…
23 terms
Diabetes (Insulin)
Glargine (Lantus)... Detemir (Levemir)
NPH (Humulin N, Novolin N)
Regular (Humulin R, Novolin R)
Aspart (Novolog)... Lispro (Humalog)... Glul…
Long-acting... analog ... basal... Onsest: 2-4h... Duration: 18-24hr
Intermediate acting ... Human ... Basal... Duration: 10-18hr
Short... Human... Prandial
Rapid Acting ... Analog ... Prandial
Glargine (Lantus)... Detemir (Levemir)
Long-acting... analog ... basal... Onsest: 2-4h... Duration: 18-24hr
NPH (Humulin N, Novolin N)
Intermediate acting ... Human ... Basal... Duration: 10-18hr
Diabetes - Insulin
T1DM & T2DM who need insulin
test to look for native insulin
Ultra short acting insulin
Short acting insulin
- FG > 280-300mg/dL... - initial A1c > 9-11%... - ketoacidosis... - ge…
C-Peptide
Aspart, lispro, & glulisine
regular
T1DM & T2DM who need insulin
- FG > 280-300mg/dL... - initial A1c > 9-11%... - ketoacidosis... - ge…
test to look for native insulin
C-Peptide
11 terms
Diabetes Insulin
Rapid acting insulin: Onset/ Peak/ Len…
Name 3 rapid acting insulins
When should a rapid acting insulin be…
Generic name: Humalog
15 minutes/ 30-90 minutes/ 3- 5 hours
Humalog (Lispro)... Aspart (Novolog)... Glulisine (Apidra)
15 minutes before eating
Trade name: Lispro
Rapid acting insulin: Onset/ Peak/ Len…
15 minutes/ 30-90 minutes/ 3- 5 hours
Name 3 rapid acting insulins
Humalog (Lispro)... Aspart (Novolog)... Glulisine (Apidra)
Diabetes and Insulin
Diabetes Mellitus:
Types of Diabetes Mellitus:
Symptoms of Diabetes Mellitus:
Diabetes Mellitus Treatment Goal:
Disorder of carbohydrate metabolism.
Type 1: Deficiency of insulin, generally develops during chil…
Sustained hyperglycemia (principle sign), polyuria, polyplasi…
Primary goal is to prevent long term complications. Tight con…
Diabetes Mellitus:
Disorder of carbohydrate metabolism.
Types of Diabetes Mellitus:
Type 1: Deficiency of insulin, generally develops during chil…
Diabetes Insulin
Lispro(Humalog) /Aspart (Novolog)... onse…
Human regular... onset, peak,duration
Human nph, lente... onset, peak,duration
Ulralente... onset, peak,duration
onset=5-10 min.... peak= 1 hr... duration= 2-4 hrs.
onset= 1/2-2 hr.... peak= 2-4 hrs.... duration= 4-6 hrs.
onset= 2-4 hrs.... peak= 4-10 hrs.... duration= 10-16
onset= 6-10 hrs.... peak= none... duration= 18-20 hrs.
Lispro(Humalog) /Aspart (Novolog)... onse…
onset=5-10 min.... peak= 1 hr... duration= 2-4 hrs.
Human regular... onset, peak,duration
onset= 1/2-2 hr.... peak= 2-4 hrs.... duration= 4-6 hrs.
40 terms
Diabetes, Insulin
How does insulin work?
Where is insulin absorbed the fastest.…
Give 6 rules for storing insulin.
2 things to remember about the injecti…
1. decreases blood glucose by;... transporting glucose into cel…
abdomen, arm, legs... Avoid: site that may be heavily exercised…
1. Store current vial at room temp, back up vials in the frid…
1. Some clients may develop uticaria at the injection site... 2.…
How does insulin work?
1. decreases blood glucose by;... transporting glucose into cel…
Where is insulin absorbed the fastest.…
abdomen, arm, legs... Avoid: site that may be heavily exercised…
22 terms
Insulin and diabetes
Muscle
Adipose
Liver
Blood glucose
Increases nutrient uptake... Increases glycogen synthesis... Increa…
Increase nutrient uptake... Fat synthesis... Activates lipoprptein…
Stimulates synthesis of glycogen and fat in liver... Stop synthe…
Usually 50 to 150 mg per 100 ml... Diabetics have 100 to 250... Lig…
Muscle
Increases nutrient uptake... Increases glycogen synthesis... Increa…
Adipose
Increase nutrient uptake... Fat synthesis... Activates lipoprptein…
20 terms
Insulin. Diabetes
A client is to receive glargine (Lantu…
The nurse is teaching the client about…
Which of the following conditions is t…
A client's 12:00 noon blood glucose wa…
Put air into the glargine insulin vial, and draw up the corre…
anything less than 70
Obesity
access for hypoglycemia
A client is to receive glargine (Lantu…
Put air into the glargine insulin vial, and draw up the corre…
The nurse is teaching the client about…
anything less than 70
10 terms
Insulin and Diabetes
Lispro (Humalog)
Aspart (Novolog)
Regular insulin (Humulin R)
NPH insulin (Humulin N)
rapid acting; clear... onset: 10-15 mins... peak: 1 hr... duration: 3…
rapid acting; clear... onset: 10-15 mins... peak: 40-50 mins... durati…
short acting; clear... onset: 30 min-1 hour... peak: 2-3 hrs... durati…
intermediate acting; cloudy... onset: 2-4 hrs... peak: 6-10 hrs... dur…
Lispro (Humalog)
rapid acting; clear... onset: 10-15 mins... peak: 1 hr... duration: 3…
Aspart (Novolog)
rapid acting; clear... onset: 10-15 mins... peak: 40-50 mins... durati…
43 terms
Insulin and Diabetes
Insulin Release Is produced by...
Insulin is released primarily in respo…
Insulin is also release in response to…
Insulin release is inhibited by...
The β cells of Islets of Langerhans in the Pancreas. ... Riboso…
Glucose
Vagal, β2 adrenergic stimulation, Leucine, Arginine and GI ho…
Somatostatin and α-adrenergic stimulation
Insulin Release Is produced by...
The β cells of Islets of Langerhans in the Pancreas. ... Riboso…
Insulin is released primarily in respo…
Glucose
9 terms
Insulin and Diabetes
Sulfonylureas and Meglinides... -ide
Glucagon
GLP1 (incretin)
DPPIV inhibitor
Function: increases secretion of insulin... MOA: blocks ATP dep…
MOA: Increases blood glucose by mobilizing glycogen storage a…
MOA: stimulates insulin secretion from pancreatic beta cells…
MOA: proline specific amino peptidase that catalyzes breakdow…
Sulfonylureas and Meglinides... -ide
Function: increases secretion of insulin... MOA: blocks ATP dep…
Glucagon
MOA: Increases blood glucose by mobilizing glycogen storage a…
14 terms
Insulin (diabetes)
Lispro... Aspart ... Onset?
Lispro... Aspart... Classification?
Regular:... (Humulin R)... (Novolin R)... (Ilet…
Lispro/ Aspart... Time of adverse reaction?
-Onset: <15 min... -Peak: 1 hr... -Duration: 3 hrs
Rapid-acting... -Given w/food
Short acting... -clear color
Mid-morning: weakness & trembling ... -Pt should eat within 15 m…
Lispro... Aspart ... Onset?
-Onset: <15 min... -Peak: 1 hr... -Duration: 3 hrs
Lispro... Aspart... Classification?
Rapid-acting... -Given w/food
65 terms
Diabetes and Insulin
Diabetes Mellitus
Type I diabetes
Type II diabetes
Endocrine Pancreas
Disorder of Carbohydrate, fat, and protein metabolism brought…
loss of beta cell function and absolute insulin deficiency
results from impaired ability of the tissues to use insulin (…
Releases hormones into the blood
Diabetes Mellitus
Disorder of Carbohydrate, fat, and protein metabolism brought…
Type I diabetes
loss of beta cell function and absolute insulin deficiency
17 terms
Insulin and diabetes
how many islets in human pancreas
what sympathetic innervation do islets…
what parasymp. innervations do islets…
islets in rats
10x6
adrenergic
cholinergic
3,000 cells, 80% are b cells
how many islets in human pancreas
10x6
what sympathetic innervation do islets…
adrenergic
1 of 10