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Study sets matching "diabetes mellitus biochemistry"

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Study sets matching "diabetes mellitus biochemistry"

56 terms
Biochemistry of Diabetes Mellitus
What are four major organs under regul…
Stress such as exercise can (inhibit/i…
TEST: List the 9 metabolic pathways th…
TEST: List whether insulin would incre…
1) Liver... 2) Adipose... 3) Muscle... 4) Brain
Stress INDUCES Catecholamine release --> glycogen and fat mob…
1) Glycolysis... 2) Gluconeogenesis... 3) Glucose uptake (GLUT tran…
1) Glycolysis INCREASES... 2) Gluconeogenesis DECREASES... 3) Gluco…
What are four major organs under regul…
1) Liver... 2) Adipose... 3) Muscle... 4) Brain
Stress such as exercise can (inhibit/i…
Stress INDUCES Catecholamine release --> glycogen and fat mob…
28 terms
Biochemistry of Diabetes Mellitus
Diabetes general description
Diabetes statistics
common features of diabetes
Effects of glucose not being cleared f…
condition in which insulin no longer regulates blood glucose…
9.3% of total population has it... > 60 : 25.9% (is age dependen…
All types create individuals that do not adequately respond t…
1. energy stores not repleted - tissues starved... 2. damages bl…
Diabetes general description
condition in which insulin no longer regulates blood glucose…
Diabetes statistics
9.3% of total population has it... > 60 : 25.9% (is age dependen…
78 terms
Diabetes Mellitus (biochemistry)
What mechanism raises the blood glucos…
What mechanism decreases (removes) the…
if there was extra Acetyl CoA, what wo…
do muscles put glucose in blood while…
1-dietary carbohydrates.... 2- two cycles that happen in liver :…
1-glycolysis ( after glucose enters the tissue when it's high…
By glycogenesis it's converted to glycogen (in fed state)... By…
no, it only gives glucose-6-phosphate. ( energy for it's self)
What mechanism raises the blood glucos…
1-dietary carbohydrates.... 2- two cycles that happen in liver :…
What mechanism decreases (removes) the…
1-glycolysis ( after glucose enters the tissue when it's high…
Biochemistry of Diabetes Mellitus
What are four major organs under regul…
Stress such as exercise can (inhibit/i…
TEST: List the 9 metabolic pathways th…
TEST: List whether insulin would incre…
1) Liver... 2) Adipose... 3) Muscle... 4) Brain
Stress INDUCES Catecholamine release --> glycogen and fat mob…
1) Glycolysis... 2) Gluconeogenesis... 3) Glucose uptake (GLUT tran…
1) Glycolysis INCREASES... 2) Gluconeogenesis DECREASES... 3) Gluco…
What are four major organs under regul…
1) Liver... 2) Adipose... 3) Muscle... 4) Brain
Stress such as exercise can (inhibit/i…
Stress INDUCES Catecholamine release --> glycogen and fat mob…
26 terms
biochemistry final Diabetes mellitus
Diabetes Mellitus
what may diabetes mellitus lead to? Re…
what is diabetes mellitus related to?
Type 1 age of onset
Polygenic syndrome Deficiency of insulin (elevated fasting bl…
*may cause adult blindness, renal failure, nerve damage, hear…
Sedentary lifestyle/obestiy
AKA childhood diabetes ... *typically during childhood/puberty (…
Diabetes Mellitus
Polygenic syndrome Deficiency of insulin (elevated fasting bl…
what may diabetes mellitus lead to? Re…
*may cause adult blindness, renal failure, nerve damage, hear…
54 terms
Biochemistry of Diabetes Mellitus
What are four major organs under regul…
Stress such as exercise can (inhibit/i…
TEST: List the 9 metabolic pathways th…
TEST: List whether insulin would incre…
1) Liver... 2) Adipose... 3) Muscle... 4) Brain
Stress INDUCES Catecholamine release --> glycogen and fat mob…
1) Glycolysis... 2) Gluconeogenesis... 3) Glucose uptake (GLUT tran…
1) Glycolysis INCREASES... 2) Gluconeogenesis DECREASES... 3) Gluco…
What are four major organs under regul…
1) Liver... 2) Adipose... 3) Muscle... 4) Brain
Stress such as exercise can (inhibit/i…
Stress INDUCES Catecholamine release --> glycogen and fat mob…
54 terms
Biochemistry of Diabetes Mellitus
What are four major organs under regul…
Stress such as exercise can (inhibit/i…
TEST: List the 9 metabolic pathways th…
TEST: List whether insulin would incre…
1) Liver... 2) Adipose... 3) Muscle... 4) Brain
Stress INDUCES Catecholamine release --> glycogen and fat mob…
1) Glycolysis... 2) Gluconeogenesis... 3) Glucose uptake (GLUT tran…
1) Glycolysis INCREASES... 2) Gluconeogenesis DECREASES... 3) Gluco…
What are four major organs under regul…
1) Liver... 2) Adipose... 3) Muscle... 4) Brain
Stress such as exercise can (inhibit/i…
Stress INDUCES Catecholamine release --> glycogen and fat mob…
54 terms
Biochemistry of Diabetes Mellitus
What are four major organs under regul…
Stress such as exercise can (inhibit/i…
TEST: List the 9 metabolic pathways th…
TEST: List whether insulin would incre…
1) Liver... 2) Adipose... 3) Muscle... 4) Brain
Stress INDUCES Catecholamine release --> glycogen and fat mob…
1) Glycolysis... 2) Gluconeogenesis... 3) Glucose uptake (GLUT tran…
1) Glycolysis INCREASES... 2) Gluconeogenesis DECREASES... 3) Gluco…
What are four major organs under regul…
1) Liver... 2) Adipose... 3) Muscle... 4) Brain
Stress such as exercise can (inhibit/i…
Stress INDUCES Catecholamine release --> glycogen and fat mob…
54 terms
Biochemistry of Diabetes Mellitus
What are four major organs under regul…
Stress such as exercise can (inhibit/i…
TEST: List the 9 metabolic pathways th…
TEST: List whether insulin would incre…
1) Liver... 2) Adipose... 3) Muscle... 4) Brain
Stress INDUCES Catecholamine release --> glycogen and fat mob…
1) Glycolysis... 2) Gluconeogenesis... 3) Glucose uptake (GLUT tran…
1) Glycolysis INCREASES... 2) Gluconeogenesis DECREASES... 3) Gluco…
What are four major organs under regul…
1) Liver... 2) Adipose... 3) Muscle... 4) Brain
Stress such as exercise can (inhibit/i…
Stress INDUCES Catecholamine release --> glycogen and fat mob…
67 terms
Endo: Biochemistry of Diabetes Mellitus - (Squire) - $$
What are four major organs under regul…
Stress such as exercise can (inhibit/i…
What is Diabetes Mellitus?
TEST: List the 9 metabolic pathways th…
1) Liver... 2) Adipose... 3) Muscle... 4) Brain
Stress INDUCES Catecholamine release ... → glycogen and fat mob…
Elevated plasma glucose levels
1) Glycolysis... 2) Gluconeogenesis... 3) Glucose uptake (GLUT tr…
What are four major organs under regul…
1) Liver... 2) Adipose... 3) Muscle... 4) Brain
Stress such as exercise can (inhibit/i…
Stress INDUCES Catecholamine release ... → glycogen and fat mob…
61 terms
9. Biochemistry of Diabetes Mellitus - Squier
What are four major organs under regul…
Stress such as exercise can (inhibit/i…
TEST: List the 9 metabolic pathways th…
TEST: List whether insulin would incre…
1) Liver... 2) Adipose... 3) Muscle... 4) Brain
Stress INDUCES Catecholamine release --> glycogen and fat mob…
1) Glycolysis... 2) Gluconeogenesis... 3) Glucose uptake (GLUT tran…
1) Glycolysis INCREASES... 2) Gluconeogenesis DECREASES... 3) Gluco…
What are four major organs under regul…
1) Liver... 2) Adipose... 3) Muscle... 4) Brain
Stress such as exercise can (inhibit/i…
Stress INDUCES Catecholamine release --> glycogen and fat mob…
54 terms
02.11_Biochemistry of Diabetes Mellitus
What are four major organs under regul…
Stress such as exercise can (inhibit/i…
TEST: List the 9 metabolic pathways th…
TEST: List whether insulin would incre…
1) Liver... 2) Adipose... 3) Muscle... 4) Brain
Stress INDUCES Catecholamine release --> glycogen and fat mob…
1) Glycolysis... 2) Gluconeogenesis... 3) Glucose uptake (GLUT tran…
1) Glycolysis INCREASES... 2) Gluconeogenesis DECREASES... 3) Gluco…
What are four major organs under regul…
1) Liver... 2) Adipose... 3) Muscle... 4) Brain
Stress such as exercise can (inhibit/i…
Stress INDUCES Catecholamine release --> glycogen and fat mob…
25 terms
L6 Biochemistry and Diabetes Mellitus
ATP Cycle
ATP Cycle (stage 1 -2)
ATP Cycle (stage 2-3)
Energy produce, what happens?
Cycle taken by ATP energy to constantly produce energy with o…
Adenine, ribosome and 3 phosphate groups (ATP) let out energy…
Through respiration ADP can then be transferred back into ATP…
A reaction which requires that energy will be close by during…
ATP Cycle
Cycle taken by ATP energy to constantly produce energy with o…
ATP Cycle (stage 1 -2)
Adenine, ribosome and 3 phosphate groups (ATP) let out energy…
61 terms
ENDO 2.13 Biochemistry of Diabetes Mellitus
What are four major organs under regul…
Stress such as exercise can (inhibit/i…
TEST: List the 9 metabolic pathways th…
TEST: List whether insulin would incre…
1) Liver... 2) Adipose... 3) Muscle... 4) Brain
Stress INDUCES Catecholamine release --> glycogen and fat mob…
1) Glycolysis... 2) Gluconeogenesis... 3) Glucose uptake (GLUT tran…
1) Glycolysis INCREASES... 2) Gluconeogenesis DECREASES... 3) Gluco…
What are four major organs under regul…
1) Liver... 2) Adipose... 3) Muscle... 4) Brain
Stress such as exercise can (inhibit/i…
Stress INDUCES Catecholamine release --> glycogen and fat mob…
67 terms
Endo: Biochemistry of Diabetes Mellitus - (Squire) - JCN
What are four major organs under regul…
Stress such as exercise can (inhibit/i…
What is Diabetes Mellitus?
TEST: List the 9 metabolic pathways th…
1) Liver... 2) Adipose... 3) Muscle... 4) Brain
Stress INDUCES Catecholamine release ... → glycogen and fat mob…
Elevated plasma glucose levels
1) Glycolysis... 2) Gluconeogenesis... 3) Glucose uptake (GLUT tr…
What are four major organs under regul…
1) Liver... 2) Adipose... 3) Muscle... 4) Brain
Stress such as exercise can (inhibit/i…
Stress INDUCES Catecholamine release ... → glycogen and fat mob…
67 terms
Endo: Biochemistry of Diabetes Mellitus - (Squire) - JCN
What are four major organs under regul…
Stress such as exercise can (inhibit/i…
What is Diabetes Mellitus?
TEST: List the 9 metabolic pathways th…
1) Liver... 2) Adipose... 3) Muscle... 4) Brain
Stress INDUCES Catecholamine release ... → glycogen and fat mob…
Elevated plasma glucose levels
1) Glycolysis... 2) Gluconeogenesis... 3) Glucose uptake (GLUT tr…
What are four major organs under regul…
1) Liver... 2) Adipose... 3) Muscle... 4) Brain
Stress such as exercise can (inhibit/i…
Stress INDUCES Catecholamine release ... → glycogen and fat mob…
61 terms
ENDO 2.13 Biochemistry of Diabetes Mellitus
What are four major organs under regul…
Stress such as exercise can (inhibit/i…
TEST: List the 9 metabolic pathways th…
TEST: List whether insulin would incre…
1) Liver... 2) Adipose... 3) Muscle... 4) Brain
Stress INDUCES Catecholamine release --> glycogen and fat mob…
1) Glycolysis... 2) Gluconeogenesis... 3) Glucose uptake (GLUT tran…
1) Glycolysis INCREASES... 2) Gluconeogenesis DECREASES... 3) Gluco…
What are four major organs under regul…
1) Liver... 2) Adipose... 3) Muscle... 4) Brain
Stress such as exercise can (inhibit/i…
Stress INDUCES Catecholamine release --> glycogen and fat mob…
30 terms
Diabetes Mellitus
Name the four types of diabetes.... What…
Type I Diabetes is a result of what?
Type II Diabetes is a result of what?
What happens to the amount of insulin…
1. Type I Diabetes - insulin dependent diabetes. The result o…
Autoimmune destruction of the pancreatic beta cells and a res…
Patients start to develop a resistance to insulin, usually as…
They decrease in number
Name the four types of diabetes.... What…
1. Type I Diabetes - insulin dependent diabetes. The result o…
Type I Diabetes is a result of what?
Autoimmune destruction of the pancreatic beta cells and a res…
20 terms
Diabetes Mellitus
diabetes mellitus
hyperglycemia
hypoglycemia
type I diabetes
Often referred to by doctors as diabetes mellitus, describes…
State in which blood glucose concentration is too high.
State in which blood glucose concentration is too low.
Autoimmune disease where beta cells are destroyed so the body…
diabetes mellitus
Often referred to by doctors as diabetes mellitus, describes…
hyperglycemia
State in which blood glucose concentration is too high.
25 terms
Diabetes Mellitus
Dawn Phenomenon
Treat with bedtime injection of NPH to…
Somogyi effect
Treat with decreased nighttime NPH dos…
Normal glucose until 2-8 am when it risis. Results from decre…
Treatment of Dawn Phenomenon
Nocturnal hypoglycemia followed by rebound hyperglycemia due…
Treatment of Somogyi effect
Dawn Phenomenon
Normal glucose until 2-8 am when it risis. Results from decre…
Treat with bedtime injection of NPH to…
Treatment of Dawn Phenomenon
171 terms
Diabetes Mellitus
Diabetes Mellitus
How much does diabetes increase a pers…
What is the number one cause of death…
What are specific (rare) types of di…
a group of metabolic diseases characterized by hyperglycemia…
increases risk 2 to 4 times
cardiovascular disease
• cystic fibrosis-related diabetes... • drug-induced (high-dose…
Diabetes Mellitus
a group of metabolic diseases characterized by hyperglycemia…
How much does diabetes increase a pers…
increases risk 2 to 4 times
126 terms
Diabetes Mellitus
insulin
insulin
glycogen
70-100
What transports and metabolizes glucose for energy?
What stimulates storage of glucose in the liver and muscle as…
Insulin stimulates storage of glucose in the liver and muscle…
The normal Fasting Blood Glucose level is?
insulin
What transports and metabolizes glucose for energy?
insulin
What stimulates storage of glucose in the liver and muscle as…
72 terms
Diabetes Mellitus
Diabetes Mellitus
Patho of Normal Pancriatic Islet
Patho of Type I DM
Patho of Type II DM
D/O of hyperglycemia from defects in insulin production, acti…
Islet is composed of Beta Islets that produce insulin ... Normal…
Auto antibodies attack Beta Cells, thus halting insulin produ…
Due to Obestiy, Sedentary L/S, Diet
Diabetes Mellitus
D/O of hyperglycemia from defects in insulin production, acti…
Patho of Normal Pancriatic Islet
Islet is composed of Beta Islets that produce insulin ... Normal…
69 terms
Diabetes Mellitus
Diabetes Mellitus
Results from defects in
leads to abnormalities
4 Major Types
characterized by chronic hyperglycemia due to inadequate insu…
-insulin secretion... -insulin action... -both
-carbohydrate metabolism... -fat metabolism
-Type 1... -Type 2... -Gestational Diabetes... -Other Specific types
Diabetes Mellitus
characterized by chronic hyperglycemia due to inadequate insu…
Results from defects in
-insulin secretion... -insulin action... -both
58 terms
Diabetes mellitus
Adrenalin
retroperitoneal
exokrine Drüse
endokrine Drüse
im Nebennierenmark gebildetes Hormon
hinter dem Bauchfell
äusserer Sekretion
innerer Sekretion
Adrenalin
im Nebennierenmark gebildetes Hormon
retroperitoneal
hinter dem Bauchfell
77 terms
Diabetes Mellitus
What is Diabetes Mellitus?
Diabete Mellitus is leading cause of w…
67% of adults with diabetes will also…
TRUE or FALSE: Drinking alcohol can in…
A chronic multi-system disease related to abnormal insulin pr…
Adult blindness... End-stage kidney disease... Non-traumatic lower…
hypertension
False- it may cause hypoglycemia if not taken with food.
What is Diabetes Mellitus?
A chronic multi-system disease related to abnormal insulin pr…
Diabete Mellitus is leading cause of w…
Adult blindness... End-stage kidney disease... Non-traumatic lower…
13 terms
Diabetes mellitus
Type 1 DM
Type 2 DM
hyperglycemia
S/S Type 1 DM
autoimmune... prior to age 30... lack of insulin
lifestyle/diet/weight risks... obesity is biggest predictor of T…
elevated levels of glucose in blood... normal blood sugar levels…
classic symptoms: 3 polys... weight loss, muscle wasting... hypergl…
Type 1 DM
autoimmune... prior to age 30... lack of insulin
Type 2 DM
lifestyle/diet/weight risks... obesity is biggest predictor of T…
23 terms
Diabetes Mellitus
What is the definition of diabetes?
What are 4 characteristic symptoms of…
What is the diagnostic criteria for di…
What is impaired glucose tolerance ass…
Chronic hyperglycaemia at levels sufficient to cause specific…
Polydipsia (thirst) and polyuria... Blurred vision... Oral/genital…
If patient symptomatic, blood tested once - twice is asymptom…
Insulin resistance, present 17% of 35-65 year olds... Significan…
What is the definition of diabetes?
Chronic hyperglycaemia at levels sufficient to cause specific…
What are 4 characteristic symptoms of…
Polydipsia (thirst) and polyuria... Blurred vision... Oral/genital…
29 terms
Diabetes Mellitus
Prediabetes
Diabetes in the Elderly
Life expectancy ____________ with the…
Two major impacts diabetes has on peop…
Elevated blood glucose... Damage beginning to CV system
Increase mortality... Increase rate of institutionalization... Incr…
decreases
leading cause of lower limb amputation and kidney disease
Prediabetes
Elevated blood glucose... Damage beginning to CV system
Diabetes in the Elderly
Increase mortality... Increase rate of institutionalization... Incr…
34 terms
Diabetes Mellitus
polydipsia
dawn phenomenon
polyphagia
polyuria
chronic thirst, excessive intake of water; it is a common sym…
early morning rise in blood glucose level related to growth h…
excessive hunger; it is a common symptom of uncontrolled diab…
increased frequency or volume of urinary output; it is a comm…
polydipsia
chronic thirst, excessive intake of water; it is a common sym…
dawn phenomenon
early morning rise in blood glucose level related to growth h…
20 terms
Diabetes Mellitus
What is diabetes mellitus?
Diabetes mellitus stats
Gestational diabetes
Gestational DM: Risks to the baby
Disorder of CHO metabolism... -Due to insufficient insulin produ…
>29 million people (≅9.3%) in U.S.... 37% of adults aged 20+ y…
Up to 9% of pregnancies... Screening at 24-28 wks... Risk factors…
Excess glucose crosses the placenta... Higher fetal insulin lev…
What is diabetes mellitus?
Disorder of CHO metabolism... -Due to insufficient insulin produ…
Diabetes mellitus stats
>29 million people (≅9.3%) in U.S.... 37% of adults aged 20+ y…
67 terms
Diabetes Mellitus
hyperglycemia
Secondary Diabetes Mellitus
Type 1 Diabetes
Type 2 Diabetes
most persistant biochemical feature of DM
Due to diseases that physically destroy pancreatic islets, ex…
caused by lack of insulin
due to loss of response and sensitivity to insulin
hyperglycemia
most persistant biochemical feature of DM
Secondary Diabetes Mellitus
Due to diseases that physically destroy pancreatic islets, ex…
14 terms
Diabetes Mellitus
Overview
Glucose metabolism
Regulation of blood glucose
Diabetes type 1
The disease diabetes mellitus is marked by inadequate insulin…
Glucose Metabolism You learned in the chapter introduction th…
Homeostasis of blood glu-... cose is remarkably effective. If yo…
When we discussed the ele-... ments essential to normal insulin…
Overview
The disease diabetes mellitus is marked by inadequate insulin…
Glucose metabolism
Glucose Metabolism You learned in the chapter introduction th…
23 terms
Diabetes Mellitus
Diabetes Mellitus central processes
Type 1 DM
Type 2 DM
Ketosis prone diabetes
B-cell failure in producing sufficient insulin and/or insulin…
-disease of β-cell failure resulting in lack of circulating i…
-initially asymptomatic and therefore not typically diagnosed…
Patients who do not have T1DM and evidence of autoantibodies…
Diabetes Mellitus central processes
B-cell failure in producing sufficient insulin and/or insulin…
Type 1 DM
-disease of β-cell failure resulting in lack of circulating i…
48 terms
Diabetes Mellitus
Glucose
diabetes mellitus
What is used for
Which cells used it the most?
Sugar or glycaemia in blood
multisystem disease with metabolic, vascular and neuropathic…
cellular respiration to make ATP... stored... as glycogen in liver…
adipose tissue, muscle and liver
Glucose
Sugar or glycaemia in blood
diabetes mellitus
multisystem disease with metabolic, vascular and neuropathic…
23 terms
Diabetes Mellitus
Definition
Type 1: IDDM or juvenile diabetes
Type 2: NIDDM or adult diabetes
Gestational diabetes
a group of diseases characterized by hyperglycemia, insulin s…
chronic endocrine disorder charaecterized by complete destruc…
impairment in insulin production, insulin resistance, and/or…
interference with insulin receptors by placental lactogen cau…
Definition
a group of diseases characterized by hyperglycemia, insulin s…
Type 1: IDDM or juvenile diabetes
chronic endocrine disorder charaecterized by complete destruc…
37 terms
Diabetes Mellitus
Diabetes is a risk factor for:
Diabetes is the ____ driver of healthc…
Define diabetes mellitus
Pathogenesis of type 2 diabetes
Blindness... Kidney Failure... Gangrene... Heart Attack... Stroke
2nd biggest
metabolic disorder from multiple etiologies... Characteristics:…
Genetic predisposition + obesity, lifestyle factors... leading t…
Diabetes is a risk factor for:
Blindness... Kidney Failure... Gangrene... Heart Attack... Stroke
Diabetes is the ____ driver of healthc…
2nd biggest
14 terms
Diabetes Mellitus
Glucotrol
Glynase
Amaryl
Micronase
Glipizide
Glyburide
Glimepiride
Glyburide
Glucotrol
Glipizide
Glynase
Glyburide
21 terms
Diabetes Mellitus
Diabetes
Being a disease of the pancreas
Regulation of blood glucose
Without insulin
A chronic disease, characterized by with a deficiency of insu…
Normally, beta cells in pancreas secrete insulin, insulin mov…
Negative feedback system... -High glucose=release insulin, gluco…
-conversion of glucose to glycogen is not longer promoted... -up…
Diabetes
A chronic disease, characterized by with a deficiency of insu…
Being a disease of the pancreas
Normally, beta cells in pancreas secrete insulin, insulin mov…
25 terms
Diabetes Mellitus
Epidemiology of diabetes
Hyperglycaemia definition
Glucosuria physiology
Polyuria physiology
Affects 2-3% population, much more common in older people (>5…
Blood glucose >10mM =renal threshold for glucose
Glucose in urine, tubular fluid exceeds renal threshold for r…
High volume of urine, osmotic diuresis due to glucose in tubu…
Epidemiology of diabetes
Affects 2-3% population, much more common in older people (>5…
Hyperglycaemia definition
Blood glucose >10mM =renal threshold for glucose
35 terms
Diabetes Mellitus
Absorptive phase
post-absorptive phase
obligatroy glucose organ
glucose sparing organ
- dominated by anabolism... - insulin production
- dominated by fat and carb catabolism... - production of glucos…
- Brain & CNS
- muscle... - burn fat when resting, not glucose
Absorptive phase
- dominated by anabolism... - insulin production
post-absorptive phase
- dominated by fat and carb catabolism... - production of glucos…
26 terms
Diabetes Mellitus
Characteristics of Diabetic Ketoacidos…
Factors that cause DKA
Pathophysiology of DKA
Long-term Complications of DM
> Hyperglycemia... > Ketosis... > Acidosis... > Dehydration
Caused by a profound lack of insulin... > Illness and Infection…
> With low insulin, glucose cannot be used for energy so fat…
> Retinopathy... > Nephropathy... - ACE inhibitors and ARBs slow p…
Characteristics of Diabetic Ketoacidos…
> Hyperglycemia... > Ketosis... > Acidosis... > Dehydration
Factors that cause DKA
Caused by a profound lack of insulin... > Illness and Infection…
26 terms
Diabetes Mellitus
Characteristics of Diabetic Ketoacidos…
Factors that cause DKA
Pathophysiology of DKA
Long-term Complications of DM
> Hyperglycemia... > Ketosis... > Acidosis... > Dehydration
Caused by a profound lack of insulin... > Illness and Infection…
> With low insulin, glucose cannot be used for energy so fat…
> Retinopathy... > Nephropathy... - ACE inhibitors and ARBs slow p…
Characteristics of Diabetic Ketoacidos…
> Hyperglycemia... > Ketosis... > Acidosis... > Dehydration
Factors that cause DKA
Caused by a profound lack of insulin... > Illness and Infection…
39 terms
diabetes mellitus
DM characteristics
normal glucose parameters
impaired fasting glucose
impaired glucose tolerance
chronic d/o w abnl metabolism of carbs, protein, fat
fasting plasma <100... 2 hour glucose <140
fasting plasma glucose 100-125
2 hour glucose 140-200
DM characteristics
chronic d/o w abnl metabolism of carbs, protein, fat
normal glucose parameters
fasting plasma <100... 2 hour glucose <140
26 terms
Diabetes Mellitus
Characteristics of Diabetic Ketoacidos…
Factors that cause DKA
Pathophysiology of DKA
Long-term Complications of DM
> Hyperglycemia... > Ketosis... > Acidosis... > Dehydration
Caused by a profound lack of insulin... > Illness and Infection…
> With low insulin, glucose cannot be used for energy so fat…
> Retinopathy... > Nephropathy... - ACE inhibitors and ARBs slow p…
Characteristics of Diabetic Ketoacidos…
> Hyperglycemia... > Ketosis... > Acidosis... > Dehydration
Factors that cause DKA
Caused by a profound lack of insulin... > Illness and Infection…
19 terms
Diabetes mellitus
Screening for DM
Diabetic meds
Complications of insulin treatment
Storage of insulin
*-fast plasma glucose (FPG) levels than or equal to 110 mg/dL…
-Insulin (used in pregnancy)... Sulfonylureas... *Alpha-glucosi…
HYPOGLYCEMIA... DI:... -Hypoglycemic agents... *-beta adrenergic…
*-Unopened vials should be stored under refrigeration until n…
Screening for DM
*-fast plasma glucose (FPG) levels than or equal to 110 mg/dL…
Diabetic meds
-Insulin (used in pregnancy)... Sulfonylureas... *Alpha-glucosi…
40 terms
Diabetes Mellitus
Diabetes Mellitus
Kidney Review
What does insulin do?
What does glucagon do?
-A chronic disease of insulin deficiency or resistance... -Insul…
Beta cells are responsible for insulin secretion (*amylin 100…
1) Mediates transport of glucose from the blood stream into c…
1) Promotes glycogenolysis (breaking down glycogen to produce…
Diabetes Mellitus
-A chronic disease of insulin deficiency or resistance... -Insul…
Kidney Review
Beta cells are responsible for insulin secretion (*amylin 100…
13 terms
Diabetes Mellitus
Biguanide
Sulfonylureas
(TZD) Thiazolidinedione
Meglitinides
Ex: Metformin... MOA: Insulin sensitizer*, dec hepatic glucose p…
Ex: Glipizide, Glyburide, Glimeperide... MOA: Insulin secretagog…
Ex: Pioglitazone (Actos), Rosiglitazone (Avandia)... MOA: Insuli…
Ex: Repaglinide (Prandin), Netaglinide (Starlix)... MOA: Short a…
Biguanide
Ex: Metformin... MOA: Insulin sensitizer*, dec hepatic glucose p…
Sulfonylureas
Ex: Glipizide, Glyburide, Glimeperide... MOA: Insulin secretagog…
46 terms
Diabetes Mellitus
insulin fuction
glycogen function
treatment of T1DM and goal
ultra short acting insulin
1. promotes the storage of glucose... 2. promotes the storage of…
inhibits synthesis of new glucose
insulin... adjunct treatment w/ synthetic amylin (pramlintide)…
insulin lispro ... 15-30 min onset; 1-2 h peak; 4-6 h duration;…
insulin fuction
1. promotes the storage of glucose... 2. promotes the storage of…
glycogen function
inhibits synthesis of new glucose
100 terms
Diabetes mellitus
How is a person diagnosed with DM?
A1C test level in DM patients
FPG/ FBS level in DM patients
2-hour PG level in DM patients
- A1C test... - Fasting plasma glucose... - 2 hour Plasma glucose... -…
> or equal 6.5 %
> or equal 126 mg/ dL ... Requirements: no calorie intake for 8…
> or equal 200 mg/ dL... During oral glucose test, pt ingest 75…
How is a person diagnosed with DM?
- A1C test... - Fasting plasma glucose... - 2 hour Plasma glucose... -…
A1C test level in DM patients
> or equal 6.5 %
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