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Study sets matching "diabetes mellitus type"

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Study sets matching "diabetes mellitus type"

33 terms
Diabetes Mellitus Type 1
What is insulin?
What is main effect of insulin?
Other effects of insulin?
Post-prandial state
Hormone that is produced in the pancreas Beta cells
to regulate glucose metabolism... Increases glucose storage and…
Fat metabolism (↑ production, ↓ breakdown) ... Protein metabolis…
after a meal
What is insulin?
Hormone that is produced in the pancreas Beta cells
What is main effect of insulin?
to regulate glucose metabolism... Increases glucose storage and…
5 terms
Diabetes Mellitus Type 2
Polyuria
Polydipsia
Hyperglycemia
Hypoglycemia
Production of abnormally large values of dilute urine.
Abnormally great thirst as a symptom of disease.
An excess of glucose in the bloodstream.
Low blood sugar.
Polyuria
Production of abnormally large values of dilute urine.
Polydipsia
Abnormally great thirst as a symptom of disease.
5 terms
Diabetes Mellitus Type 2
Polyuria
Polydipsia
Hyperglycemia
Hypoglycemia
A condition usually defined as excessive or abnormally large…
Excessive thirst or excess drinking.
(High blood sugar) A condition in which an excessive amount o…
(Low blood sugar) When blood sugar decreases to below normal…
Polyuria
A condition usually defined as excessive or abnormally large…
Polydipsia
Excessive thirst or excess drinking.
32 terms
Type 2 Diabetes Mellitus
RIsk factors for T2DM
Diagnostic Criteria for Diabetes tests
HbA1c levels for diagnosing
FPG levels in diangoisng
Genetic: Family history, thrifty genes, genetic markers... Demo…
FPG ... 2 hour PG ... random glucose... HBA1C
HbA1c less than 5.7% is normal.... HbA1c between 5.7% and 6.4% r…
FPG - fasting plasma glucose, IFG is impaired fasting glucose…
RIsk factors for T2DM
Genetic: Family history, thrifty genes, genetic markers... Demo…
Diagnostic Criteria for Diabetes tests
FPG ... 2 hour PG ... random glucose... HBA1C
60 terms
Diabetes Mellitus Type 2
What is diabetes mellitus? What are th…
What is Type II DM and why does it no…
MC form of diabetes?
Etiology of DM 2?
Group of metabolic disorders characterized by hyperglycemia…
Chronic condition that affects the way your body metabolizes…
TYPE 2 DIABETES... MC form of diabetes (90-95%)... Prevalence risi…
Strong genetic component... Identical twins, parents w/DM Envir…
What is diabetes mellitus? What are th…
Group of metabolic disorders characterized by hyperglycemia…
What is Type II DM and why does it no…
Chronic condition that affects the way your body metabolizes…
13 terms
Diabetes Mellitus Type 2
A dysfunction in glucose metabolism th…
Risk factors = ... a. family history (str…
Historically diagnosed after age (40 y…
H/P = ... a. (asymptomatic or symptomatic…
Development of tissue resistance to insulin , leading to hy…
b. exercise
40yr
a. asymptomatic... b. polydipsia... c. hyperglycemia... d. Nonketotic
A dysfunction in glucose metabolism th…
Development of tissue resistance to insulin , leading to hy…
Risk factors = ... a. family history (str…
b. exercise
52 terms
Type 1 Diabetes Mellitus
this is a chronic disorder with elevat…
diabetes mellitus can be a _______ or…
what are the 4 types of diabetes melli…
what are diseases of the pancreas that…
diabetes mellitus
-primary... -secondary
-type 1 diabetes... -type 2 diabetes... -gestational ... -malnutrition…
-pancreatitis... -hemochromatosis
this is a chronic disorder with elevat…
diabetes mellitus
diabetes mellitus can be a _______ or…
-primary... -secondary
18 terms
Diabetes mellitus type 1
How much of the endocrine pancreas mus…
What are the classes of type 1 diabete…
Differentiate between autoimmune DM1 i…
List some autoantibodies which are pre…
Over 90%
1) Immune-mediated (Autoimmune DM1) = the presence of autoant…
In children:... - Usually rapidly developing... - Usually AAI antib…
- ICA (Islets Cell Antibodies)... - IAA (Insulin Auto Antibodies…
How much of the endocrine pancreas mus…
Over 90%
What are the classes of type 1 diabete…
1) Immune-mediated (Autoimmune DM1) = the presence of autoant…
5 terms
Diabetes Mellitus Type 2
polyuria
polydispsia
hyperglycemia
hypoglycemia
...
...
...
...
polyuria
...
polydispsia
...
10 terms
Diabetes Mellitus type 2
Diabetes type 2
Biguanides (metformin)
Alpha-glucosidase (Acarbose, Miglitol)
Thiazolidinediones (TZDs)... pioglitazone…
When the beta cells produce too little insulin
main site of action: Liver... Keep the liver from releasing too…
main site of action: intestine... Slow the digestion of some car…
main site of action: muscle cells... Make muscle and fat cells m…
Diabetes type 2
When the beta cells produce too little insulin
Biguanides (metformin)
main site of action: Liver... Keep the liver from releasing too…
43 terms
Diabetes Mellitus Type 1
Diabetes facts
Diabetes
types of diabetes
blood glucose
many people... 90-95% have type 2... 6th leading cause of death…
A condition in which the body cannot make or cannot use insul…
Type I... Formerly known as :... juvenile diabetes... "brittle" diabe…
Sugar (glucose) is ... an important source ... of energy... Insulin i…
Diabetes facts
many people... 90-95% have type 2... 6th leading cause of death…
Diabetes
A condition in which the body cannot make or cannot use insul…
9 terms
Type 2 Diabetes Mellitus
____ = impaired glucose tolerance or i…
_____ = defective response of cell rec…
complications and sequelae of diabetes…
FPG for diabetes = ___
prediabetes
type 2 diabetes mellitus
hypoglycemia, hyperglycemia, neuropathy, angiopathy, podiatri…
>126 mg/dl
____ = impaired glucose tolerance or i…
prediabetes
_____ = defective response of cell rec…
type 2 diabetes mellitus
5 terms
Diabetes mellitus type 2
Polyuria
Polydipsia
Hyperglycemia
Hypoglycemia
frequent urination
abnormaly great thirst
an exess of glucose in the bloodstream
low blood sugar
Polyuria
frequent urination
Polydipsia
abnormaly great thirst
5 terms
Type 2 Diabetes Mellitus
Polyuria
Polydipsia
Hyperglycemia
Hypoglycemia
Frequent urination
Abnormally great thirst
An excess of glucose in the bloodstream
Low blood sugar
Polyuria
Frequent urination
Polydipsia
Abnormally great thirst
14 terms
Type 1 diabetes mellitus
Type 1 diabetes mellitus ... 1. epidemiol…
aetiology of diabetes mellitus
Natural history of disease progression
characteristic features of type 1 diab…
1. Insulin dependent diabetes ... 2. autoimmune destruction of b…
1. autoimmune disorder ... - destruction of beta cells ... 2. genet…
1. genetic predisposition ... 2. inductive event ... 3. islet antig…
classical symptoms ... - polydypsia ... - polyphagia ... - polyuria ... -…
Type 1 diabetes mellitus ... 1. epidemiol…
1. Insulin dependent diabetes ... 2. autoimmune destruction of b…
aetiology of diabetes mellitus
1. autoimmune disorder ... - destruction of beta cells ... 2. genet…
5 terms
Diabetes Mellitus Type 2
Polyuria
Polydipsia
Hyperglycemia
Hypoglycemia
the passing of an excessive quantity of urine, as in diabetes…
excessive thirst
an abnormally high level of glucose in the blood
an abnormally low level of glucose in the blood
Polyuria
the passing of an excessive quantity of urine, as in diabetes…
Polydipsia
excessive thirst
86 terms
Diabetes mellitus type 2
How many children and adults in the US…
New cases of diabetes
About 1 in every ________ children and…
ADA Screening recommendations: 1
25.8 million children and adults in US... 8.3% of the population
1.9 million new cases of diabetes are diagnosed in people age…
1 in 400
1) Testing should be considered in all adults who are overwei…
How many children and adults in the US…
25.8 million children and adults in US... 8.3% of the population
New cases of diabetes
1.9 million new cases of diabetes are diagnosed in people age…
13 terms
Diabetes Mellitus type 1
Diabetes Mellitus type 1
Long-Acting Insulin... Also called basal…
Intermediate-acting Insulin
Short acting insulin
When the beta cells of the pancreas do not produce any insulin
Insulin Glargine (lantus), Determir (levemir)... Starts: 1.5 to…
NPH (Humulin N or Novolin N) ... Starts: 1-3 hours ... peaks: 4- 15…
Regular insulin (Humulin R or Novolin R)... Starts 30 to 60 min…
Diabetes Mellitus type 1
When the beta cells of the pancreas do not produce any insulin
Long-Acting Insulin... Also called basal…
Insulin Glargine (lantus), Determir (levemir)... Starts: 1.5 to…
85 terms
Type 2 Diabetes Mellitus
Approach for obese pt (10 steps)
Prediabetes
Glucose Tolerance Test levels for dx
Screening for Diabetes in Asymptomatic…
1. Measure ht & wt --> BMI at ALL visits... 2. Measure waist c…
Blood glucose levels higher than NL but not high enough for…
FPG: pre-DM = > 100 mg/dL & DM = > 126 mg/dL... 2h glucose: pre-…
Start at 45 y/o... Repeat every year in those with Pre-diabetes…
Approach for obese pt (10 steps)
1. Measure ht & wt --> BMI at ALL visits... 2. Measure waist c…
Prediabetes
Blood glucose levels higher than NL but not high enough for…
Type I Diabetes Mellitus
20
no
less than 5 years old
American Indian
What percentage of adolescents with type 2 diabetes mellitus…
Is there an insulin regimen (multiple daily injections / insu…
In which age group is type 1 DM increasing?
In which ethnic group is the incidence of T2DM higher than T1…
20
What percentage of adolescents with type 2 diabetes mellitus…
no
Is there an insulin regimen (multiple daily injections / insu…
19 terms
Diabetes Mellitus Type 2
Definition
Epidemiology
Pathophysiology (insulin)
Pathophys (glucagon)
Progressive hyperglycemia state... --non ketotic ... --continuum of…
Extremely prevalent (and increasing)... -7,800/100,000 (29 milli…
Insulin resistance ... -impaired glucose uptake ... -receptor des…
Paradoxical gluconeogenesis ... -inappropriate response to carbo…
Definition
Progressive hyperglycemia state... --non ketotic ... --continuum of…
Epidemiology
Extremely prevalent (and increasing)... -7,800/100,000 (29 milli…
28 terms
Type 2 Diabetes Mellitus
largest portion of diabetes by ethnicity
diagnostic criteria for diabetes : fas…
diagnostic criteria for diabetes: 2 ho…
random plasma glucose diagnostic crite…
hispanic
FPG: normal: <100; IFG : 100-125 diabetes: >126
normal: <140... IGT: 140-199... diabetes: >200
>200 and symptoms of diabetes
largest portion of diabetes by ethnicity
hispanic
diagnostic criteria for diabetes : fas…
FPG: normal: <100; IFG : 100-125 diabetes: >126
33 terms
Diabetes Mellitus type 1
Rapid-acting
Short-acting
Intermediate-Acting
Long-acting
most closely mimic the body's natural insulin response - lysi…
Given in response to an elevated blood glucose and/or expecte…
Given to offset the effects of post-parandial Blood Glucose e…
Usually given once a day; increasingly popular as a basal ins…
Rapid-acting
most closely mimic the body's natural insulin response - lysi…
Short-acting
Given in response to an elevated blood glucose and/or expecte…
17 terms
Type 1 Diabetes Mellitus
Diabetes Mellitus
Diabetes Mellitus ... Definitions
Diabetes Mellitus... Glucose regulating h…
Diabetes Mellitus... INSULIN and Glucagon…
pancreas endocrine gland. exocrine- secretes into a duct, lip…
*Glucose- 6 carbon molecule, circulating- need insulin to use…
*insulin: essential, its the key that unlocks cells so cells…
insulin... carbs: INCREASES glucose uptake in tissues, glycogen…
Diabetes Mellitus
pancreas endocrine gland. exocrine- secretes into a duct, lip…
Diabetes Mellitus ... Definitions
*Glucose- 6 carbon molecule, circulating- need insulin to use…
9 terms
Diabetes Mellitus Type I
Genetics: HLA genes
Genetics: Rare Monogenic Forms
Genetics: IL-2 receptor gene
Potential Autoantigens
Human Leukocyte Antigen genes code for surface proteins of an…
Common in many autoimmune disorders, causes disruptions in re…
Regulatory T-cells rely on IL-2 for growth and survival; IL-2…
Proinsulin, insulin, GAD 65, GAD 67.
Genetics: HLA genes
Human Leukocyte Antigen genes code for surface proteins of an…
Genetics: Rare Monogenic Forms
Common in many autoimmune disorders, causes disruptions in re…
7 terms
Diabetes Mellitus Type 1
Definition of Diabetes
Type 1 Diabetes
Age of Onset for Type 1
Risk Factors for Type 1
a metabolic disorder characterized by a relative or absolute…
autoimmune, have to take insulin are they're going to die, kn…
young age, between 8-12, can be as young as 2, accounts for a…
maybe runs in the family, but little genetic pattern, it is v…
Definition of Diabetes
a metabolic disorder characterized by a relative or absolute…
Type 1 Diabetes
autoimmune, have to take insulin are they're going to die, kn…
16 terms
Type II Diabetes Mellitus
Type I vs Type II
Type II Diabetes Mellitus... Etiology
Type II Diabetes Mellitus... Risk factors
Type II Diabetes Mellitus... Metabolic sy…
no insulin in Type 1: no endogenous insulin... resistance in Typ…
used to be called adult onset, metabolic syndrome. insulin re…
-genetics: highly, much more strongly linked to Type II... -obes…
constellation of conditions that lead to perfect storm. centr…
Type I vs Type II
no insulin in Type 1: no endogenous insulin... resistance in Typ…
Type II Diabetes Mellitus... Etiology
used to be called adult onset, metabolic syndrome. insulin re…
43 terms
Diabetes Mellitus Type 1
Diabetes facts
Diabetes
types of diabetes
blood glucose
many people... 90-95% have type 2... 6th leading cause of death…
A condition in which the body cannot make or cannot use insul…
Type I... Formerly known as :... juvenile diabetes... "brittle" diabe…
Sugar (glucose) is ... an important source ... of energy... Insulin i…
Diabetes facts
many people... 90-95% have type 2... 6th leading cause of death…
Diabetes
A condition in which the body cannot make or cannot use insul…
33 terms
Diabetes Mellitus Type 1
What is insulin?
What is main effect of insulin?
Other effects of insulin?
Post-prandial state
Hormone that is produced in the pancreas Beta cells
to regulate glucose metabolism... Increases glucose storage and…
Fat metabolism (↑ production, ↓ breakdown) ... Protein metabolis…
after a meal
What is insulin?
Hormone that is produced in the pancreas Beta cells
What is main effect of insulin?
to regulate glucose metabolism... Increases glucose storage and…
46 terms
diabetes mellitus type 2
risk factors
mechanisms
insulin resistance
beta cell dysfunction
age... obesity... hypertension... physical inactivity... family history... m…
-alteration production of adipokines- leptin resistance... -INC…
-response of insuin sensitive tissues- (lver,muscle,adipose)…
decrease in beta cell mass... inflammation and changes occur in…
risk factors
age... obesity... hypertension... physical inactivity... family history... m…
mechanisms
-alteration production of adipokines- leptin resistance... -INC…
68 terms
Diabetes Mellitus Type II
Diabetes Type II Facts
Risk Factors for DM II
DM II in Children
Reason for increasing prevalences if D…
MOST COMMON type of diabetes... About 90% of DM II have a posi…
Overweight/Obese... - Increased abdominal girth... Over 45 years o…
Epidemic... Almost always obese... Members of an at risk populati…
overweight/obesity has increased... Overweight childen become o…
Diabetes Type II Facts
MOST COMMON type of diabetes... About 90% of DM II have a posi…
Risk Factors for DM II
Overweight/Obese... - Increased abdominal girth... Over 45 years o…
127 terms
Type 2 Diabetes Mellitus
What is the primary problem in T2DM?
What lifestyle risk factors are for T2…
What ethnicities have risk factors for…
What co-morbidities are risk factors f…
Insulin Resistance
Sedentary lifestyle... increased consumption of high-fat foods... l…
African Americans... Native Americans... Latinos... Asian Americans... Pa…
CAD... HF... CKD... Liver dysfunction
What is the primary problem in T2DM?
Insulin Resistance
What lifestyle risk factors are for T2…
Sedentary lifestyle... increased consumption of high-fat foods... l…
20 terms
Diabetes Mellitus Type I
insulin does what to striated muscle (3)
when is glucagon utilized
when is insulin utilized
what cell produces glucagon
increase glucose uptake,... increase glycogen synthesis,... increas…
in the long period of time between meals
absorptive state- right after meals
alpha cell in the pancreas
insulin does what to striated muscle (3)
increase glucose uptake,... increase glycogen synthesis,... increas…
when is glucagon utilized
in the long period of time between meals
17 terms
Type 2 Diabetes Mellitus
At what age will someone, without any…
How often should screening take place…
Adults at any age should be screened f…
A blood pressure of _________ or great…
45
Every three years
Have a BMI of 25 or more AND have one or more additional risk…
>140/90
At what age will someone, without any…
45
How often should screening take place…
Every three years
43 terms
Diabetes Mellitus Type 1
Remind me again, what is DM?
What is type 1 DM?
Rate of destruction of Beta cells is m…
When do symptoms begin in DM1?
• Too much circulating glucose... • Insulin is not working to d…
Type I is a failure of the pancreas to produce insulin... Cellu…
Rate of destruction of β-cells is rapid in children, slower i…
WHEN 80% of the islets are destroyed! ... o Kids present with D…
Remind me again, what is DM?
• Too much circulating glucose... • Insulin is not working to d…
What is type 1 DM?
Type I is a failure of the pancreas to produce insulin... Cellu…
14 terms
Diabetes mellitus type 1
What is it?
Genetic susceptibility
Environmental factors
Major histocompatibility complex
Pancreatic atrophy and loss of beta cells ... Gradual loss of is…
1st degree relative (parent/sibling) with type 1... Strongest as…
Viral infection... Helicobacter pylori... Exposure to cows milk pro…
Marker- every cell contains. indicates immune system that the…
What is it?
Pancreatic atrophy and loss of beta cells ... Gradual loss of is…
Genetic susceptibility
1st degree relative (parent/sibling) with type 1... Strongest as…
20 terms
Diabetes Mellitus Type II
postprandial
incretin hormones
which incretin has greatest effect
effect that GLP-1 has on insulin and g…
after a meal
hormones secreted by small intestine cells that stimulate pos…
GLP-1 (glucagon-like-peptide)
insulin increases glucagon decreases
postprandial
after a meal
incretin hormones
hormones secreted by small intestine cells that stimulate pos…
15 terms
Diabetes Mellitus Type 2
Insulin
Signs and Symptoms of Diabetes
Contributing factors for diabetes
What is metabolic syndrome
Key that allows glucose to enter cell (decreased blood sugar)…
Frequently no real symptoms... Fatigue or recurrent infections…
Overweight... Dyslipidemia... Hyperinsulemic... Hypertensive
Cluster of conditions that increase the risk of heart disease…
Insulin
Key that allows glucose to enter cell (decreased blood sugar)…
Signs and Symptoms of Diabetes
Frequently no real symptoms... Fatigue or recurrent infections…
108 terms
Type 1 Diabetes Mellitus
What is the pathophysiology of T1DM?
What are the four stages of T1DM?
How often should a T1DM SMBG?
What are the signs/symptoms of T1DM?
Immune-mediated and idiopathic processes--> destruction of be…
1) Preclinical period (environmental triggers and immune mark…
6-10 times/day
1) Polyphagia... 2) Polydipsia... 3) Polyuria... 4) Weight Loss... 5) Fat…
What is the pathophysiology of T1DM?
Immune-mediated and idiopathic processes--> destruction of be…
What are the four stages of T1DM?
1) Preclinical period (environmental triggers and immune mark…
52 terms
Type II Diabetes Mellitus
Diabetic Complications: microvascular
Diabetic Complications: Macrovasculature
What is the pathophysiology of microva…
How does peripheral neuropathy present?
Diabetic Kidney Disease/Nephropathy ... Retinopathy ... Neuropath…
Atherosclerotic Cardiovascular Disease (ASCVD)... Cerebrovascula…
Hyperglycemia causes endothelial damage and thickening of cap…
Paresthesias, dysesthesias, numbness in both hands and feet,…
Diabetic Complications: microvascular
Diabetic Kidney Disease/Nephropathy ... Retinopathy ... Neuropath…
Diabetic Complications: Macrovasculature
Atherosclerotic Cardiovascular Disease (ASCVD)... Cerebrovascula…
45 terms
Type 2 Diabetes mellitus
What s the difference to type 1
What happens to insulin production
Due to the increase in beta cells, wha…
Why does DKA not tend to occur in type…
Production of insulin is still there but the cells don't resp…
Increases (beta cell hyperplasia and hypertrophy)... Needs more…
Amylin
As well as Hyperglycaemia there is also still insulin being p…
What s the difference to type 1
Production of insulin is still there but the cells don't resp…
What happens to insulin production
Increases (beta cell hyperplasia and hypertrophy)... Needs more…
6 terms
Diabetes Mellitus Type 1
`Factors that increase insulin secreti…
Factors that decrease insulin secretion:
What does Glucagon do?
What are each of the GLUT channels for?
Increased BGL... Increased blood free fatty acids... Increased bloo…
Decreased BGL... Fasting... Somatostatin... Leptin
Acts mainly on the liver and works by increasing cAMP... 1. Prom…
GLUT-1: Transport glucose across blood-brain barrier and eryt…
`Factors that increase insulin secreti…
Increased BGL... Increased blood free fatty acids... Increased bloo…
Factors that decrease insulin secretion:
Decreased BGL... Fasting... Somatostatin... Leptin
26 terms
Diabetes Mellitus Type 2
what increases your chances of having…
what are the criteria for diagnosis of…
what defines pre-diabetes
what is the biggest precursor for card…
-obesity... -increased caloric intake... -decreased caloric expendi…
-random glucose over 200... -FPG over 126... -GTT over 200... -HgbA1C…
-FBG between 100 and 125... -GTT between 140-199... -HgbA1C between…
-impaired glucose tolerance test
what increases your chances of having…
-obesity... -increased caloric intake... -decreased caloric expendi…
what are the criteria for diagnosis of…
-random glucose over 200... -FPG over 126... -GTT over 200... -HgbA1C…
11 terms
Type 1 Diabetes Mellitus
When does type 1 DM typically occur?
Usually the Symptoms are the three P's
*Increased levels of what in urine pro…
Polyuria
During childhood or puberty and average onset is 16
Polyuria... Polydipsia ... Polyphagia
Glucose
Increase in urine volume
When does type 1 DM typically occur?
During childhood or puberty and average onset is 16
Usually the Symptoms are the three P's
Polyuria... Polydipsia ... Polyphagia
22 terms
Diabetes Mellitus Type 1
What is the leading cause of kidney fa…
How is DM diagnosed?
Which medication are used to treat neu…
Which medicine for neuropathy has seve…
Diabetes
- symptoms of DM- RBG >200 mg/dL (polyuria, polydipsia, unexp…
Gabapentin
Metoclopramide
What is the leading cause of kidney fa…
Diabetes
How is DM diagnosed?
- symptoms of DM- RBG >200 mg/dL (polyuria, polydipsia, unexp…
19 terms
Type 2 Diabetes Mellitus
What is Diabetes Mellitus?
What is a standard blood test diagnosi…
Another way is to perform a 75g glucos…
What is type 2 Diabetes Mellitus?
A condition where the blood glucose is above an international…
Blood glucose of >11.1 mmol/l + symptoms... OR... Blood glucose of…
...
A condition where Beta cells cannot produce enough insulin to…
What is Diabetes Mellitus?
A condition where the blood glucose is above an international…
What is a standard blood test diagnosi…
Blood glucose of >11.1 mmol/l + symptoms... OR... Blood glucose of…
25 terms
Diabetes Mellitus Type 1
Define Diabetes Mellitus T1
What causes DM T1?
What is the prevalence of DM T1 in the…
Who presents with DM T1?
Metabolic hyperglycaemic condition caused by absolute insuffi…
Destruction of the pancreatic insulin-producing Beta cells.…
0.25% (One of the most common chronic diseases in childhood.
Juvenile onset (<30yrs)
Define Diabetes Mellitus T1
Metabolic hyperglycaemic condition caused by absolute insuffi…
What causes DM T1?
Destruction of the pancreatic insulin-producing Beta cells.…
13 terms
Diabetes Mellitus (Type 1)
What condition produces a patient's sy…
An injury was most likely sustained to…
What is the most likely contributing f…
What is the most likely clinical prese…
Multi-system disease... persistent hyperglycemia due to diminish…
autoimmune disease; circulating insulin is very low or absent…
autoimmune process with a strong genetic component
starts in children ages 4+... polyuria (diluted urine)... polydipsi…
What condition produces a patient's sy…
Multi-system disease... persistent hyperglycemia due to diminish…
An injury was most likely sustained to…
autoimmune disease; circulating insulin is very low or absent…
15 terms
Patho: Diabetes Mellitus Type 1
Cause of Type I
Glucose moves through glucose transpor…
GLUT-1
GLUT 2
-Auto immune destruction of B cells of pancreas... ---Believed t…
GLUT 1-4
ubiquitous
B cells of pancreas... --very low affinity, serves as trigger fo…
Cause of Type I
-Auto immune destruction of B cells of pancreas... ---Believed t…
Glucose moves through glucose transpor…
GLUT 1-4
22 terms
19 - Type 1 Diabetes Mellitus
Diabetes Mellitus Definition
Main Types of Diabetes Mellitus and Pr…
Other Etiologies of Diabetes
Diagnostic Criteria for Diabetes
Metabolic disorder characterized by elevated blood sugars
Type 1 - inadequate level of insulin, autoimmune process dest…
- Genetic defects in beta cells (MODY, Wolfram, mito disorder…
- A1C > 6.5 ... OR ... - Fasting Glucose > 125... OR ... - 2-hour Glucose…
Diabetes Mellitus Definition
Metabolic disorder characterized by elevated blood sugars
Main Types of Diabetes Mellitus and Pr…
Type 1 - inadequate level of insulin, autoimmune process dest…
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