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Study sets matching "drugs anti"

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Study sets matching "drugs anti"

24 terms
Pharmacology: Anti-inflammatory Drugs
- Short-acting... * hydrocortisone (often…
Acetylsalicylic Acid... * phenylbutazone…
** COX-2 selective inhibitor NSAIDs... -…
Dimethyl Sulfoxide (DMSO)
Glucocorticoids
Non-Selective COX Inhibitors, NSAIDs
COX-2 Selective Inhibitors NSAIDs and Dual Path Inhibitor NSA…
Free-Radical Scavengers
- Short-acting... * hydrocortisone (often…
Glucocorticoids
Acetylsalicylic Acid... * phenylbutazone…
Non-Selective COX Inhibitors, NSAIDs
25 terms
AntiHTN drugs
RAAS
Blood pressure
Chlorthalidone
Hydrochlorothiazide (HCTZ)
Increases SNS activity... Leads to Na and volume retention... May…
Cardiac output X Peripheral Resistance
Thiazide diuretic - block Na/Cl pump in DCT decreasing reabso…
Thiazide diuretic - block Na/Cl pump in DCT decreasing reabso…
RAAS
Increases SNS activity... Leads to Na and volume retention... May…
Blood pressure
Cardiac output X Peripheral Resistance
8 terms
Anti-Manic & Anti-ADHD Drugs
Anti-Mania
Lithium
Carbamazepine
Valproate
1. Lithium... 2. Carbamazepine... 3. Valproate
mood stabilizer; (cardiotoxicity & neurotoxicity); folliculit…
mood stabilizer
lipid
Anti-Mania
1. Lithium... 2. Carbamazepine... 3. Valproate
Lithium
mood stabilizer; (cardiotoxicity & neurotoxicity); folliculit…
39 terms
22. Anti-rheumatic drugs
RA is common in men or women?
Describe the pathophys of RA
inflammatory mediators associated with…
NSAIDs for RA
common in men (3x)
- chronic inflammation of the synovial tissue lining the join…
CIKE... - complement factors... - IL-1... - kinins... - eicosanoids
- effective for reducing pain and inflammation BUT requires h…
RA is common in men or women?
common in men (3x)
Describe the pathophys of RA
- chronic inflammation of the synovial tissue lining the join…
68 terms
Anti-Coag and Anti-Platelet Drugs
Clopidogrel (class)
Clopidogrel binding
Clopidogrel metabolism (one to two step)
Prasugrel class
thienopyridine - P2Y12 receptor antagonist
irreversible
two
thienopyridine - P2Y12 receptor antagonist
Clopidogrel (class)
thienopyridine - P2Y12 receptor antagonist
Clopidogrel binding
irreversible
40 terms
Anti-arrhythmic drugs
definition
electrical spread
cell mPv threshold
fast cardiac action potential
variation in site/rate of cardiac impulse formation and/or va…
SA node ... atria... AV node (slow)... his purkinje system activates... v…
-90mv
definition
variation in site/rate of cardiac impulse formation and/or va…
electrical spread
SA node ... atria... AV node (slow)... his purkinje system activates... v…
27 terms
Anti-emetics and Anti Nausea Drugs
Anticholinergic Drugs
Anticholinergic Drugs Mech of Action
Anticholinergic Indications
Anticholinergic Drug Effects
Scopolamine (Transderm-scop, Scopace)
Block ACh receptors in the vestibular nuclei and reticular fo…
Motion, sickness, Secretion reduction before surgery, nausea…
CNS: Dizziness, drowsiness, disorientation... CV: Tachycardia... EE…
Anticholinergic Drugs
Scopolamine (Transderm-scop, Scopace)
Anticholinergic Drugs Mech of Action
Block ACh receptors in the vestibular nuclei and reticular fo…
42 terms
ANTI CANCER DRUGS
Log kill Hypothesis:
Growth Fraction:
Cell Cycle Specific Agents... Antimetabo…
Classification of Anti cancer drugs ... C…
Destruction of cancer cells by chemotherapeutic agents follow…
Cytotoxic drugs are more effective against tumors that have a…
Cell Cycle Non-Specific Agents... Alkylating Agents... Antibiotic…
Cell cycle specific:... S phase - Anti metabolites (6 mercaptop…
Log kill Hypothesis:
Destruction of cancer cells by chemotherapeutic agents follow…
Growth Fraction:
Cytotoxic drugs are more effective against tumors that have a…
17 terms
Anti-hypertensive drugs
Thiazide
Beta-blockers
ACE Inhibitors
Angiotensin II receptor blockers (ARB)
Diuretic, lowers BP by increasing sodium and water excretion…
Blocks sympathetic stimulation and decreases CO.
Blocks the enzyme that normally converts angiotensin I to the…
Compete with angiotensin II for tissue binding sites
Thiazide
Diuretic, lowers BP by increasing sodium and water excretion…
Beta-blockers
Blocks sympathetic stimulation and decreases CO.
20 terms
CNS: Anti-parkinsons drugs
parkinson's disease
Parkinson's Disease Neurochemistry
levodopa
biosynthesis of Levodopa
•Neurological disease affecting over four million patients wo…
•ACh controls muscle contraction via the five muscarinic rece…
-is used to increase dopamine concentrations in the treatment…
•Once L-DOPA has entered the central nervous system (CNS), it…
parkinson's disease
•Neurological disease affecting over four million patients wo…
Parkinson's Disease Neurochemistry
•ACh controls muscle contraction via the five muscarinic rece…
34 terms
drugs anti-trafficking operations
The government claims to be doing all…
She hired an assassin to eliminate her…
There has been a series of police crac…
We landed at a tiny airstrip in the mi…
There's no point in arresting the small fry. We've got bigger…
They were charged with peddling drugs to young children.
Most scientists believe it is legitimate to experiment on ani…
In ​their ​latest ​drugs bust ​police ​entered a ​warehouse w…
The government claims to be doing all…
There's no point in arresting the small fry. We've got bigger…
She hired an assassin to eliminate her…
They were charged with peddling drugs to young children.
60 terms
2016: Anti-cancer Drugs
Primary Induction Therapy
Neoadjuvant Chemotherapy
Adjuvant Chemotherapy
Consolidation Chemotherapy
-chemotherapy is the primary treatment in advanced disease fo…
-a type of induction therapy in which the goal is to REDUCE L…
-surgery or radiotherapy is the primary therapy (followed by…
-treatment after cancer is no longer detectable following ini…
Primary Induction Therapy
-chemotherapy is the primary treatment in advanced disease fo…
Neoadjuvant Chemotherapy
-a type of induction therapy in which the goal is to REDUCE L…
27 terms
Anti-emetics and Anti Nausea Drugs
Anticholinergic Drugs
Anticholinergic Drugs Mech of Action
Anticholinergic Indications
Anticholinergic Drug Effects
Scopolamine (Transderm-scop, Scopace)
Block ACh receptors in the vestibular nuclei and reticular fo…
Motion, sickness, Secretion reduction before surgery, nausea…
CNS: Dizziness, drowsiness, disorientation... CV: Tachycardia... EE…
Anticholinergic Drugs
Scopolamine (Transderm-scop, Scopace)
Anticholinergic Drugs Mech of Action
Block ACh receptors in the vestibular nuclei and reticular fo…
22 terms
Anti-Malarial DRUGS
MALARIA:
DRUG CLASSIFICATION
DRUGS
Treatment of malaria:... Plasmodium spp:…
Malaria is caused by a single-cell protozoa, the plasmodium.…
Tissue Schizonticides drugs that eliminate developing or dor…
CHLOROQUINE... QUININE... MEFLOQUINE _ BLOOD SCHIZONTICIDES... PYRIMET…
Chloroquine ... Chloroquine ... Chloroquine + Primaquine... Chloroqui…
MALARIA:
Malaria is caused by a single-cell protozoa, the plasmodium.…
DRUG CLASSIFICATION
Tissue Schizonticides drugs that eliminate developing or dor…
25 terms
Anti-epileptic Drugs
Adults with Partial Onset: Initial Mon…
Children with Partial Onset: Initial M…
Elderly with Partial Onset: Initial Mo…
Adults with Generalized Tonic Clonic:…
Phenytoin, Carbamazepine, Leviteracetam, Zonisamide, Valproic…
Oxcarbazepine
Gabapentin, Lamotrigine
Carbamazepine, Lamotrigine, Oxcarbazepine, Phenobarbital, Phe…
Adults with Partial Onset: Initial Mon…
Phenytoin, Carbamazepine, Leviteracetam, Zonisamide, Valproic…
Children with Partial Onset: Initial M…
Oxcarbazepine
27 terms
Anti protozoal drugs
parasites
Endoparasite:... Protozoa:Amoeba,giardia,…
CHEMOTHERAPY OF AMEBIASIS
Classification
...
Ectoparasite:... Lice,Mite
Amoebiasis or Amebic dysentery is caused by ENTAMOEBA HISTOLY…
Mixed Amoebicides:... Act in both luminal and systemic forms of…
parasites
...
Endoparasite:... Protozoa:Amoeba,giardia,…
Ectoparasite:... Lice,Mite
7 terms
Cardiac Drugs: Anti-arrhythmic Drugs
Quinidine
Procainamide
Lidocaine
Propranolol
NA+ Channel Blockers (Class I)... Use: treatment of arterial fib…
NA+ Channel Blockers (Class I)... Use: long-term control of prem…
NA+ Channel Blockers (Class I)... Use: short-term control of PCV…
Beta-blockers (Class II)... Use: treatment for HCM and various a…
Quinidine
NA+ Channel Blockers (Class I)... Use: treatment of arterial fib…
Procainamide
NA+ Channel Blockers (Class I)... Use: long-term control of prem…
17 terms
Anti-inflammatory Drugs
Therapeutic strategies for inflammation
Agents used for treatment of inflammat…
Chemistry and Pharmacokinetics of NSAIDS
Pharmacodynamics of NSAIDS
2 Goals:... 1) Relief of inflammatory-related symptoms and maint…
NSAIDS... - Analgesic effects... - Treat both acute and chronic inf…
- Most are well absorbed and highly metabolized in the liver…
Primary MOA is inhibition of cyclooxygenase (COX) enzymes... - R…
Therapeutic strategies for inflammation
2 Goals:... 1) Relief of inflammatory-related symptoms and maint…
Agents used for treatment of inflammat…
NSAIDS... - Analgesic effects... - Treat both acute and chronic inf…
201 terms
MC: Anti-arrhythmic Drugs
Learning Objectives slide
What do you mean by cell depolarization?
What is the resting membrane potential…
Repolarization mainly involves
Sodium influx
-90mV
Potassium ions
Learning Objectives slide
What do you mean by cell depolarization?
Sodium influx
75 terms
Anti-Arrhythmic Drugs
Class 1 Agents Mechanism
Class 1a Effects
Class 1a ADs
CLass 1a Agents
Na+ channel blocker
-modest Na+ effect... -increases refractory period... -increases AP…
-thrombocytopenia... -torsades de pointes (QT prolongation)
Quinidine... Procainamide... Disopyramide... ^^^rarely used
Class 1 Agents Mechanism
Na+ channel blocker
Class 1a Effects
-modest Na+ effect... -increases refractory period... -increases AP…
22 terms
Anti-Viral Drugs
Miraviroc
Enfuvirtide
(N)NRTI
Nevirapine
Chemokine co-receptor Blocker (for HIV). Blocks CD4 co-recept…
Fusion inhibitor (HIV). Prevents fusion of cell membrane and…
(Non)-Nucleoside Reverse Transcriptase Inhibitors... All preven…
NNRTI... Non-nucleoside Reverse Transcriptase blocker (HIV).... Bi…
Miraviroc
Chemokine co-receptor Blocker (for HIV). Blocks CD4 co-recept…
Enfuvirtide
Fusion inhibitor (HIV). Prevents fusion of cell membrane and…
40 terms
Anti-infective Drugs
Amoxil
Clavulin
Orbenin
PenVee
amoxicillin... Penicillin family
Amoxicillin+ clavulanic acid... Penicillin family
Cloxacillin... Penicillin family
Penicillin V... Penicillin family
Amoxil
amoxicillin... Penicillin family
Clavulin
Amoxicillin+ clavulanic acid... Penicillin family
27 terms
Anti-emetics and Anti Nausea Drugs
Anticholinergic Drugs
Anticholinergic Drugs Mech of Action
Anticholinergic Indications
Anticholinergic Drug Effects
Scopolamine (Transderm-scop, Scopace)
Block ACh receptors in the vestibular nuclei and reticular fo…
Motion, sickness, Secretion reduction before surgery, nausea…
CNS: Dizziness, drowsiness, disorientation... CV: Tachycardia... EE…
Anticholinergic Drugs
Scopolamine (Transderm-scop, Scopace)
Anticholinergic Drugs Mech of Action
Block ACh receptors in the vestibular nuclei and reticular fo…
15 terms
Heme - Anti-coagulant Drugs
Heparin
Heparin
Heparin OD
Heparin-induced Thrombocytopenia
Short acting... Constant IV infusion... Indirectly inhibits thro…
Bleeding... Bone loss... Osteoporosis... Heparin-induced Thrombocyto…
Protamine sulfate... - binds
- heparin binds to Platelet factor 4 --> auto-antibodies ag…
Heparin
Short acting... Constant IV infusion... Indirectly inhibits thro…
Heparin
Bleeding... Bone loss... Osteoporosis... Heparin-induced Thrombocyto…
25 terms
Anti-Cancer /Immunosuppressant Drugs
Azathioprine, 6-mercaptopurine
Cladribine (2-CDA)
Cytarabine (arabinofuranosyl cytidine)
5-FU
Purine (thiol) analogs, decrease de novo purine synthesis. Ac…
Purine analog--multiple mechanisms. ... Use: Hairy cell leukemia…
Pyrimidine analog--> inhibition of DNA polymerase.... Use: Leuke…
Pyrimidine analog bioactivated to 5F-dUMP, which covalently c…
Azathioprine, 6-mercaptopurine
Purine (thiol) analogs, decrease de novo purine synthesis. Ac…
Cladribine (2-CDA)
Purine analog--multiple mechanisms. ... Use: Hairy cell leukemia…
23 terms
Pharmacology: Anti-Diabetic Drugs
Types of Diabetes Mellitus
Insulin Biochemistry
Insulin Biology
Insulin Mechanism of Action
-Type I: Absence of insulin production; most severe type; m…
-Two chains: A (21 aa) and B (30 aa)... -Insulin is a protein sy…
Regulation of Insulin:... -Insulin is secreted at a low basal ra…
-Insulin binds to specific receptors on cell surface... -Recepto…
Types of Diabetes Mellitus
-Type I: Absence of insulin production; most severe type; m…
Insulin Biochemistry
-Two chains: A (21 aa) and B (30 aa)... -Insulin is a protein sy…
8 terms
Anti-inflammatory and Anti-gout drugs
Asprin
Acetylsalicylic acid (ASA)
ibuprofen
naproxen
NSAID
Salicylate
NSAID (advil)
NSAID (aleve/naprosyn)
Asprin
NSAID
Acetylsalicylic acid (ASA)
Salicylate
46 terms
Anti-Fungal and Anti-Parasitic Drugs
Ergosterol
Amphotericin B
Amphotericin B
Amphotericin B
Biosynthesis... 1. Squalene + squalene epoxidase (inhibited by a…
Mechanism... -Polyene; disrupts fungal membrane function... -Binds…
Clinical Use... -Serious, systemic mycoses; "gold standard"; mus…
Toxicity... -Fever/chills ("shake and bake")... -Hypotension... -Nephr…
Ergosterol
Biosynthesis... 1. Squalene + squalene epoxidase (inhibited by a…
Amphotericin B
Mechanism... -Polyene; disrupts fungal membrane function... -Binds…
29 terms
Anti-inflammatory drugs
COX-1
COX-2
misoprostol
Cardiovascular
Which COX enzyme is constituitively expressed?
Highly inducable COX isoform
Drug given as a prostaglandin analogue for people with a hist…
COX-2 inhibitors have the highest rate of [system] adverse ef…
COX-1
Which COX enzyme is constituitively expressed?
COX-2
Highly inducable COX isoform
46 terms
Anti-epileptics= anti-sezure drugs
Phenobarbitol... Mechanism... Indications... PK
Phenytoin/ Dilantin... Indications... Mechan…
Ethosuximide/ Zarontin... Mechanism... Indic…
Benzodiazepines (diazepam, lorazepam,…
cheap and very effective... Mechanism: GABA receptor agonist- op…
Cheap... INDICATIONS: ... -effective against all seizure types exc…
Mechanism: blocks T-type Ca++ channels found in the thalamus…
Indications: ... -Drug of choice for status epilepticus, alcohol…
Phenobarbitol... Mechanism... Indications... PK
cheap and very effective... Mechanism: GABA receptor agonist- op…
Phenytoin/ Dilantin... Indications... Mechan…
Cheap... INDICATIONS: ... -effective against all seizure types exc…
28 terms
Nonsteroidal AntiInflammatory Drugs
Some Questions
General Outline
Significance of NSAIDs
Vioxx
Why is Aspirin Used as a Blood Thinner? Can NSAIDs Hurt the F…
LOOK AT SLIDE
Prostaglandins are the NSAID Targets which are Produced from…
Double the persons risk of Heart Attack + Stroke. Selective C…
Some Questions
Why is Aspirin Used as a Blood Thinner? Can NSAIDs Hurt the F…
General Outline
LOOK AT SLIDE
24 terms
Anti arrhythmic Drugs
Antiarrhythmic Drugs 4 Classes
Miscelaneous Drugs
Action potential phases
Class 1A: activated Na+ chanel
Class 1: Na+ Channel Blockers... Class 2: Beta Blocker... Class 3:…
Adenosine, Digoxin, Magnesium Sulfate
Phase 0- increase Na... Depolarization... Phase 1-increase Ca... Over…
Quinidine, procainamide, and disopyramide
Antiarrhythmic Drugs 4 Classes
Class 1: Na+ Channel Blockers... Class 2: Beta Blocker... Class 3:…
Miscelaneous Drugs
Adenosine, Digoxin, Magnesium Sulfate
132 terms
Arrhythmias & Anti-Arrhythmic Drugs
Increased automaticity (normal or ecto…
slope of phase 4 depolarization, thres…
conduction, refractory period, prematu…
AP duration, calcium
The goal of anti-arrhythmic therapy is to stop tachyarrhythmi…
Tachyarrhythmias caused by increased automaticity (normal or…
Tachyarrhythmias caused by reentrant pathways can be stopped…
Tachyarrhythmias caused by triggered activity can be stopped…
Increased automaticity (normal or ecto…
The goal of anti-arrhythmic therapy is to stop tachyarrhythmi…
slope of phase 4 depolarization, thres…
Tachyarrhythmias caused by increased automaticity (normal or…
201 terms
MC: Anti-arrhythmic Drugs
Learning Objectives slide
What do you mean by cell depolarization?
What is the resting membrane potential…
Repolarization mainly involves
Sodium influx
-90mV
Potassium ions
Learning Objectives slide
What do you mean by cell depolarization?
Sodium influx
35 terms
Anti-Anginal and Anti-Platelet Drugs
angina
angina
coronary atherosclerosis
classic
a symptomatic manifestation of myocardial ischemia, caused by…
chest pain
generally the major underlying cause of classic angina
type of angina, stable, reduced blood flow to heart muscle du…
angina
a symptomatic manifestation of myocardial ischemia, caused by…
angina
chest pain
12 terms
Anti HIV drugs MOA
zidovudine
azidothymidine (AZT)
ritonavir
saquinavir
- analog of thymidine that is recognized by thymidine kinase…
increases CD4 count in AIDS patients, toxic to bone marrow an…
protease can cleave at Phe residues at either side of the hyd…
HIV protease can cleave at proline residues, this drug contai…
zidovudine
- analog of thymidine that is recognized by thymidine kinase…
azidothymidine (AZT)
increases CD4 count in AIDS patients, toxic to bone marrow an…
24 terms
Pharmacology - Anti Convulsant Drugs
Simple Partial Seizure (begin focally…
Complex Partial Seizure (begin focally…
Generalized Convulsive Seizures
Absence (petit mal) Generalized
preservation of consciousness, e.g.... focal motor, jacksonian,…
gradual loss of consciousness, may... begin with simple seizure,…
involve both hemispheres of cortex from the beginning
(< 30 sec) sudden impaired consciousness, staring, blinking,…
Simple Partial Seizure (begin focally…
preservation of consciousness, e.g.... focal motor, jacksonian,…
Complex Partial Seizure (begin focally…
gradual loss of consciousness, may... begin with simple seizure,…
10 terms
Anti-Depressant and Anti-Maniac Drugs
Amitriptyline, Nortriptyline
Tricyclic Anti-depressants
*Selective Serotonin Re-uptake Inhibit…
Duloxetine, Venlafaxine
"First generation" tricyclic anti-depressants, inhibit NET…
Inhibit re-uptake of biogenic amines Generally well-absorbe…
*Fluoxetine, sertraline, paroxetine, citalopram, escitalopram…
*(Selective) Serotonin-Norepinephrine Re-uptake Inhibitors (S…
Amitriptyline, Nortriptyline
"First generation" tricyclic anti-depressants, inhibit NET…
Tricyclic Anti-depressants
Inhibit re-uptake of biogenic amines Generally well-absorbe…
26 terms
Anti Cancer Drugs
Melphalan
Cyclophosphoramide
Lomustine
Mitomycin C
Nitrogen mustard (have 2chloroethyl groups). Carbonium ion is…
Nitrogen mustard (2 chloroethyl). Alkylates @ G7, induces Cro…
Nitrosourea, a group that has at least 1 chloroethyl group bu…
Aziridine, that has a Quinone group therefore must first be a…
Melphalan
Nitrogen mustard (have 2chloroethyl groups). Carbonium ion is…
Cyclophosphoramide
Nitrogen mustard (2 chloroethyl). Alkylates @ G7, induces Cro…
14 terms
Anti-Nausea and Anti-emetic Drugs
Scopalamine
Buclizine
Dimenhydrinate
Meclizine
Muscarinic Receptor Antagonist
Histamine (H1) Receptor Antagonist
Histamine (H1) Receptor Antagonist
Histamine (H1) Receptor Antagonist
Scopalamine
Muscarinic Receptor Antagonist
Buclizine
Histamine (H1) Receptor Antagonist
33 terms
Anti-Inflammatory and Anti-Gout Drugs
Xanthine oxidase inhibitor, antigout,…
Allopurinal (Zyloprim)
Inhibits the production of uric acid b…
Decreased blood counts and potentially…
Indication of Allopurinal
Anti-Gout
MOA of Allopurinal
Side Effects of Allopurinal
Xanthine oxidase inhibitor, antigout,…
Indication of Allopurinal
Allopurinal (Zyloprim)
Anti-Gout
36 terms
Pharm- Anti Cancer drugs
Antimetabolites- 5-flurouracil and cap…
Antimetabolites- 6-mercaptopurine
Antimetabolites- 6-thioguanine, cytara…
Antimetabolites- Methotrexate
Antimetabolites- 5-flurouracil and cap…
Antimetabolites- 6-mercaptopurine
36 terms
Pharm- Anti Cancer drugs
Antimetabolites- 5-flurouracil and cap…
Antimetabolites- 6-mercaptopurine
Antimetabolites- 6-thioguanine, cytara…
Antimetabolites- Methotrexate
Antimetabolites- 5-flurouracil and cap…
Antimetabolites- 6-mercaptopurine
29 terms
Pharm Anti-Hypertensive Drugs
Symptoms and consequences of hypertens…
DIURETICS
Proximal tubule
Loop diuretics
-Headache, fatigue, confusion, pounding in the chest, neck, o…
-increase the excretion of salt and water!... -classified by sit…
-acetozolamide and mannitol
-In thick ascending limb of Henle... -representative drug - Furo…
Symptoms and consequences of hypertens…
-Headache, fatigue, confusion, pounding in the chest, neck, o…
DIURETICS
-increase the excretion of salt and water!... -classified by sit…
59 terms
Anti-inflammatory drugs
acetominophen
positives of acetominophen
negatives of acetominophen
what acetaminophen metabolite mediates…
treats pain, fever... NOT anti-inflammatory (non-NSAID)
no GI irritation or effects on blood (no blood clotting/thinn…
not anti-inflammatory (limits use for chronic conditions)... big…
NAPQI... converted via multiple p450s... initial damage can be repa…
acetominophen
treats pain, fever... NOT anti-inflammatory (non-NSAID)
positives of acetominophen
no GI irritation or effects on blood (no blood clotting/thinn…
29 terms
Anti-fungal drugs (Dukhande)
Systemic Infections
Opportunistic Infections
Pneumocystitis jirovencii
Fungal Cell Wall
coccidiomycosis, Histoplasmosis, Blastomycosisi
Candidiasis, Thrush, Vulvovaginitis-candida albicans: GI trac…
a fungus but drugs that work for it are antiprotozoal and ant…
1. Mannan... 2 beta glucan... 3. Chitin
Systemic Infections
coccidiomycosis, Histoplasmosis, Blastomycosisi
Opportunistic Infections
Candidiasis, Thrush, Vulvovaginitis-candida albicans: GI trac…
40 terms
Anti hypertensive drugs
Blood pressure
How reduce blood pressure by drugs ?
Mechanisms of Beta blockers in lowerin…
Clinical uses of Beta-blockers other h…
determined by cardiac output & total peripheral resistance.
- either reduce blood volume, dilate arterial & or venous blo…
• decreasing heart rate & cardiac output ... • reduce rennin rel…
- angina pectoris... - cardiac dysrhythmias... - thyrotoxicosis ... -…
Blood pressure
determined by cardiac output & total peripheral resistance.
How reduce blood pressure by drugs ?
- either reduce blood volume, dilate arterial & or venous blo…
107 terms
Anti-Arrhythmic Drugs
It is only during Phase ______________…
HCN channels generate funny current --…
________________ is active in all auto…
_____________ has the highest intrinsi…
0
channel open when the membrane repolarizes (other Na channels…
Phase 4 Automatic Depolarization
SA Node (more HCN channels)
It is only during Phase ______________…
0
HCN channels generate funny current --…
channel open when the membrane repolarizes (other Na channels…
41 terms
Anti arrhythmias drugs
action potential of the heart depends on
Phases of cardiac cycle
Classification of anti arrhythmias drugs
Write about Disopyramide
ionic movement into & out of cardiac cells in resting state
Phase 0 is due to rapid depolarization of the cell membrane…
Class I => sodium channel blockade. ... • slow the maximum rat…
• antimuscarinic ... • negative inotropic effects more than *qui…
action potential of the heart depends on
ionic movement into & out of cardiac cells in resting state
Phases of cardiac cycle
Phase 0 is due to rapid depolarization of the cell membrane…
10 terms
Anti-Parkinson Drugs
Sinemet
Tasmar
Mirapex
Symmetrel
carbidopa/levodopa
tolcapone
pramipexole
amantadine
Sinemet
carbidopa/levodopa
Tasmar
tolcapone
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