Study sets matching "drugs diabetes"

Study sets
Classes
Users

Study sets matching "drugs diabetes"

18 terms
Diabetes Drugs
aspart insulin
detemir
glargine
lispro insulin
Bolus (prandial) insulins (i.e. rapid-acting)... primary goal i…
Basal insulins (i.e. long-acting)... primary goal is fasting gl…
Basal insulins (i.e. long-acting)... primary goal is fasting gl…
Bolus (prandial) insulins (i.e. rapid-acting)... primary goal i…
aspart insulin
Bolus (prandial) insulins (i.e. rapid-acting)... primary goal i…
detemir
Basal insulins (i.e. long-acting)... primary goal is fasting gl…
14 terms
Diabetes drugs
Major Classes- MoA and AEs:... Biguanide…
MoA of Metformin
GLP1 Agonists
MoA for GLP1 Agonists
-Decreases hepatic glucose production ... -Increases insulin se…
exenatide, exenatide ER, liraglutide
mimics glucagon like peptide (GLP) to stimulate pancreatic se…
Major Classes- MoA and AEs:... Biguanide…
MoA of Metformin
-Decreases hepatic glucose production ... -Increases insulin se…
diabetes drugs
Rapid acting insulin
Short acting insulin
Intermediate acting insulin
Long acting insulin
lispro (Humalog), aspart (NovoLog)... Structure nearly identic…
regular (Humulin-R), (Novolin-R)... Short-acting... Can be admini…
NPH (Humulin-N), (Novolin-N)... Intermediate acting... Cloudy solu…
glargine (Lantus)... Long-acting... Clear solution... SQ injection on…
Rapid acting insulin
lispro (Humalog), aspart (NovoLog)... Structure nearly identic…
Short acting insulin
regular (Humulin-R), (Novolin-R)... Short-acting... Can be admini…
drugs diabetes
sulfonylureas... GLUCOTROL
nursing sufonylureas
biguanine
nursing biguanine
glyburide... diabeta... micronase... glynase... glucocotrol
actioon-produces insulin... causes low blood sugar... take 30 min b…
glucophage... metformin
decreases liver production of glucose/increases insulin sensa…
sulfonylureas... GLUCOTROL
glyburide... diabeta... micronase... glynase... glucocotrol
nursing sufonylureas
actioon-produces insulin... causes low blood sugar... take 30 min b…
77 terms
diabetes drugs
long
long
intermediate
short
glargine: __ acting
detemir: __ acting
NPH: __ acting
regular: __ acting
long
glargine: __ acting
long
detemir: __ acting
Diabetes Drugs
Actoplus Met
Actos
Beyetta
Glucophage
Pioglitazone Metformin
Pioglitazone
Exenatide (pen shot)
Metformin
Actoplus Met
Pioglitazone Metformin
Actos
Pioglitazone
16 terms
Diabetes Drugs
Insulins
Long Acting Insulins
Short Acting Insulins
Intermediate Acting Insulin
Glargine... Demeter... Aspart... Lispro... Glulisine... NPH... Regular insulin
Detemir... Glargine
Lispro... Aspart... Glulisine
NPH
Insulins
Glargine... Demeter... Aspart... Lispro... Glulisine... NPH... Regular insulin
Long Acting Insulins
Detemir... Glargine
11 terms
Diabetes drugs
insulin
sulfonylurea
TZD
GLP-1 agonist
- ULTRA FAST: lispro. SHORT ACTING: regular. INTERMEDIATE…
-Glyburide, glimepiride, glipizide, glibenclamide, chlorpro…
-pioglitazone, rosiglitazone... -MECHANSIM: *increases sensiti…
-exenatide... -MECHANISM: encourages insulin secretion by ac…
insulin
- ULTRA FAST: lispro. SHORT ACTING: regular. INTERMEDIATE…
sulfonylurea
-Glyburide, glimepiride, glipizide, glibenclamide, chlorpro…
101 terms
Diabetes Drugs
Sulfonylureas bind to its receptor on…
Sulfonylureas cause A1C to drop an est…
Sulfonylureas affects this/these gluco…
Using sulfonylureas, _% of the max dos…
beta, ATP dependent potassium, close, depolarizes, calcium, o…
1, 2
Fasting... PP
50, 80
Sulfonylureas bind to its receptor on…
beta, ATP dependent potassium, close, depolarizes, calcium, o…
Sulfonylureas cause A1C to drop an est…
1, 2
13 terms
Diabetes drugs
regular insulin... advers effects
short-acting insulin... names
long-acting insulin... names
acarbose & miglitol... MoA
hypoglycemia... weight gain
lispro... aspart... glulisine
glargine... detemir
inhibit intestinal α-glucosidase (postprandial hyperglycemia…
regular insulin... advers effects
hypoglycemia... weight gain
short-acting insulin... names
lispro... aspart... glulisine
Diabetes Drugs
What is first line tx for type 2 diabe…
Insulin mechanism
insulin indication
how do you give insulin
exercise and weight control. If this isn't enough, add drugs.…
binds to insulin receptors, dimerization and phosphorylation…
only tx for type 1 diabetes
peptide not active PO, so give sub Q (IV or IM in emergency s…
What is first line tx for type 2 diabe…
exercise and weight control. If this isn't enough, add drugs.…
Insulin mechanism
binds to insulin receptors, dimerization and phosphorylation…
diabetes drugs
glipizide (Glucotrol)
metformin (Glucophage)
pioglitazone (Actos)
acarbose (Precose)
class: secretagogues ... route: oral... side effects: hypoglycemi…
class: meglitinide analogs ... route: oral... side effects: abdomi…
class: insulin sensitizers ... route: oral... side effects: incre…
alpha-glucosidase inhibitors ... route: oral... side effects: ... ab…
glipizide (Glucotrol)
class: secretagogues ... route: oral... side effects: hypoglycemi…
metformin (Glucophage)
class: meglitinide analogs ... route: oral... side effects: abdomi…
21 terms
Diabetes Drugs
Insulin lispro [Humalog]
Insulin aspart [NovoLog]
Insulin glulisine [Apidra]
Regular Insulin [Humulin R]
Rapid acting insulin, onset <30min short duration 3-5 hours…
Rapid acting insulin, onset <30min short duration 3-5 hours…
Rapid acting insulin, onset <30min short duration 3-5 hours…
Short acting (onset 15-60 min, duration 6-10 hrs)... Administere…
Insulin lispro [Humalog]
Rapid acting insulin, onset <30min short duration 3-5 hours…
Insulin aspart [NovoLog]
Rapid acting insulin, onset <30min short duration 3-5 hours…
93 terms
Diabetes Drugs
Januvia (sitagliptin phosphate)
Januvia (sitagliptin phosphate)
Januvia (sitagliptin phosphate)
Januvia (sitagliptin phosphate)
This drug is used for manage type 2 diabetes mellitus with di…
It slows inactivation of inretin hormones (incretin normally…
There is increased insulin release and decreased glucagon lev…
Helps lower blood sugar after meals and between meals. It imp…
Januvia (sitagliptin phosphate)
This drug is used for manage type 2 diabetes mellitus with di…
Januvia (sitagliptin phosphate)
It slows inactivation of inretin hormones (incretin normally…
Diabetes Drugs
diabetes 1
diabetes 2
when are adults screened for type 2 di…
what kids should be screened for diabe…
- autoimmune, b cell destruction... - *absolute insulin deficien…
- insulin secretory defect... - insulin resistance... - adult onset…
- @ 45 w/o risk factors... -repeat q 3 yrs if test normal
- age 10 and overweight... - + two of following w/ pos family hx…
diabetes 1
- autoimmune, b cell destruction... - *absolute insulin deficien…
diabetes 2
- insulin secretory defect... - insulin resistance... - adult onset…
39 terms
Diabetes Drugs
Rapid Acting Insulins
Short Acting Insulins
Intermediate Acting Insulins
Long Acting Insulins
Insulin Lispro... Insulin Aspart... Insulin Glulisine
Regular Insulin
NPH. (Cloudy in vial)
Insulin Glargine... Insulin Detemir
Rapid Acting Insulins
Insulin Lispro... Insulin Aspart... Insulin Glulisine
Short Acting Insulins
Regular Insulin
18 terms
Diabetes Drugs
Sulfonylurea (SUR)
2-deoxyglucose
MeglitinIDES
Diazoxide
2nd Gen: GLYBURIDE, GLIPIZIDE... 1st Gen: Tolbutamide, Tolazamid…
Analog of glucose which cannot be metabolized. Competes with…
RepaglinIDE (Prandin), Naglitinide... Closes K+/ATP channel whic…
Forces Beta cell K+/ATP channel to stay open. Prevents cell f…
Sulfonylurea (SUR)
2nd Gen: GLYBURIDE, GLIPIZIDE... 1st Gen: Tolbutamide, Tolazamid…
2-deoxyglucose
Analog of glucose which cannot be metabolized. Competes with…
Diabetes Drugs
Lispro
Aspart
Glulisine
Regular U-500
Humalog ... Fast acting Insulin
Novolog ... Fast acting Insulin
Apidra... Fast acting insulin
Fast acting insulin
Lispro
Humalog ... Fast acting Insulin
Aspart
Novolog ... Fast acting Insulin
32 terms
Diabetes Drugs
Metformin
Glyburide
Glipizide
Glimepiride
Glucophage, Riomet
Diabeta, Micronase
Glucotrol, Glucotrol XR
Amaryl
Metformin
Glucophage, Riomet
Glyburide
Diabeta, Micronase
Diabetes Drugs
Humalog
Humulin N
Lantus
ActorPlus Met
insulin lispro... Insulin... Diabetes mellitus
insulin NPH... Insulin... Diabetes mellitus
insulin glargine... Insulin... Diabetes mellitus
pioglitasone/metformin... Biguanide/thiazolidinedione... Type 2 d…
Humalog
insulin lispro... Insulin... Diabetes mellitus
Humulin N
insulin NPH... Insulin... Diabetes mellitus
Diabetes drugs
MOA: closes K+ ch on β-cells --> depol…
Insulin-dependent glucose channel
MOA of α-glucosidase inhibitors
MOA: agonist at PPARγ Rs --> improved…
Sulfonylureas
GLUT4 = in adipose & skeletal muscle
inhibits α-glucosidase at intestinal brush border
Glitazones, Thiazolidinediones (TZD)
MOA: closes K+ ch on β-cells --> depol…
Sulfonylureas
Insulin-dependent glucose channel
GLUT4 = in adipose & skeletal muscle
21 terms
Diabetes Drugs
Metformin
Acarbose
Exenatide
Liraglutide
Fortamet, Riomet, Glucophage
Precose
Byetta, Bydureon
Victoza
Metformin
Fortamet, Riomet, Glucophage
Acarbose
Precose
Diabetes Drugs
Novolog and Humalog
Rapid acting peak time
Rapid acting onset
Rapid acting duration
rapid-acting insulin
30-90 minutes
15 minutes
3-5 hours
Novolog and Humalog
rapid-acting insulin
Rapid acting peak time
30-90 minutes
116 terms
Diabetes Drugs
Type II DM Insulin Resistance and Hype…
Drugs with Hyperglycemic Effects
Different Forms of DM
Drugs with Hyperglycemic Effects
Hyperinsulinemia --> Insulin Resistance... Insulin Resistance -…
Glucocorticoids: cortisol contributes to insulin resistance,…
Diabetes secondary to :... - pancreatic disease... - other endocrin…
Epinephrine: induces glycogenolysis --> increases blood glucose
Type II DM Insulin Resistance and Hype…
Hyperinsulinemia --> Insulin Resistance... Insulin Resistance -…
Drugs with Hyperglycemic Effects
Glucocorticoids: cortisol contributes to insulin resistance,…
Diabetes Drugs
Metformin... (Biguanides)
Glipizide, Glyburide, Glimepiride... (Sul…
Repaglinide, Nateglinide... (Meglitinides)
Acarbose, Miglitol... (alpha-Glucosidase…
DRUG OF CHOICE, ALWAYS FIRST, Monotherapy you can add to... ant…
Added onto Metformin... Stimulates insulin secretion... Glimepirid…
Insulin-releasing agents... blocks ATP-sensitive K channel... *sh…
Cause flatulence and GI upset, thus poor patient compliance
Metformin... (Biguanides)
DRUG OF CHOICE, ALWAYS FIRST, Monotherapy you can add to... ant…
Glipizide, Glyburide, Glimepiride... (Sul…
Added onto Metformin... Stimulates insulin secretion... Glimepirid…
Diabetes Drugs
Lispro
Aspart
Glulisine
Regular
Rapid acting Insulin
Rapid acting insulin
Rapid acting insulin
Short acting insulin
Lispro
Rapid acting Insulin
Aspart
Rapid acting insulin
7 terms
Diabetes - Drugs
Metformin: Brand name?
Metformin: Strengths of 3 Forms?
Metformin: Dosing
Metformin: Indication
Glucophage, Glucophage XR, Fortamet, Glumetza, Riomet
IR: 500mg, 850mg, 1000mg... ER: 500mg, 750mg, 1000mg... Riomet Liqu…
Start: IR 500mg BID or 850mg QD... Start ER 500-1000mg WITH DINN…
First line for T2DM and may use for prevention
Metformin: Brand name?
Glucophage, Glucophage XR, Fortamet, Glumetza, Riomet
Metformin: Strengths of 3 Forms?
IR: 500mg, 850mg, 1000mg... ER: 500mg, 750mg, 1000mg... Riomet Liqu…
39 terms
Diabetes Drugs
Insulin Rapid Acting... Aspart, Glulisine…
Use of insulin rapid acting
Insulin, short acting... regular use
Insulin intermediate acting ... NPH
binds insulin receptor (tyrosine kinase activity)... liver: incr…
T I DM... Type II DM... GDM (postprandial glucose control)
T I DM, T2 DM, GDM, DKA, hyperkalemia... stress hyperglycemia
T 1 DM... T 2 DM... GDM
Insulin Rapid Acting... Aspart, Glulisine…
binds insulin receptor (tyrosine kinase activity)... liver: incr…
Use of insulin rapid acting
T I DM... Type II DM... GDM (postprandial glucose control)
Diabetes Drugs
Insulin Lispro, Aspart, Glulisine
Insulin
Insulin NPH
Insulin Glargine, Detemir
Diabetes... Rapid-acting insulin analog (5-15 min) subQ
Diabetes... Short-acting (30 min) IV
Diabetes... Intermediate-acting (2-5 h)
Diabetes... Long-acting insulin analog (24 h)
Insulin Lispro, Aspart, Glulisine
Diabetes... Rapid-acting insulin analog (5-15 min) subQ
Insulin
Diabetes... Short-acting (30 min) IV
14 terms
diabetes drugs
insulin lispro
regular insulin
NPH insulin
insulin glargine
ultra short acting insulin preparation 15 to 30 minute onset.…
short acting insulin. 30 minute to 1 hour onset. 2 to 3 hour…
intermediate insulin. 2 to 4 hour onset, 4-6 hour peak, 14-18…
long acting. delayed onset duration up to 24 hours
insulin lispro
ultra short acting insulin preparation 15 to 30 minute onset.…
regular insulin
short acting insulin. 30 minute to 1 hour onset. 2 to 3 hour…
9 terms
Diabetes Drugs
Lispro
Regular Insulin
Neutral protamine Hagedorn (NPH) insul…
Glargine
Class: modified recombinant insulin --rapid acting (3-5 hrs)…
Class: Recombinant Zn insulin --short acting (5-7 hrs)... ROA: s…
Class: combo Zn insulin and protamine; intermediate acting (1…
Class: modified recombinant insulin --long acting (20-24 hrs)…
Lispro
Class: modified recombinant insulin --rapid acting (3-5 hrs)…
Regular Insulin
Class: Recombinant Zn insulin --short acting (5-7 hrs)... ROA: s…
37 terms
Diabetes Drugs
Ultra-rapid acting insulins (onset, pe…
Lispro (class of insulin)
Aspart (class of insulin)
Glulisine (class of insulin)
O: 10min... P: .5-1 hr... D: 3-4 hrs
Ultra-rapid acting
Ultra-rapid acting
Ultra-rapid acting
Ultra-rapid acting insulins (onset, pe…
O: 10min... P: .5-1 hr... D: 3-4 hrs
Lispro (class of insulin)
Ultra-rapid acting
19 terms
Diabetes Drugs
Renal dysfunction
Severe liver dysfunction
Overweight/ obese
Heart failure
Metformin, Glyburide
Most except insulin
TZD
TZD, metformin (only unstable/severe)
Renal dysfunction
Metformin, Glyburide
Severe liver dysfunction
Most except insulin
71 terms
Diabetes drugs
Insulin Secretagogues
Sulfonylurea Agents
Insulin Sensitizers
Thiazolidinediones (TZD)
stimulate insulin release from pancreas beta cells and are us…
trigger the release of insulin from the beta cells
decreases liver glucose production, therby reducing fasting p…
improve insulin sensitivity and reduce liver glucose production
Insulin Secretagogues
stimulate insulin release from pancreas beta cells and are us…
Sulfonylurea Agents
trigger the release of insulin from the beta cells
Diabetes drugs
note
HbA1C
Glyburide
Glipizide
resistant to insuliin so all it has is glucagon unopposed and…
over 6.5% is diagnostic for diabetes- shows for the past 3 mo…
sulfonylureas... insulin secretagogue... increase insulin release…
sulfonylureas... insulin secretagogue... increase insulin release…
note
resistant to insuliin so all it has is glucagon unopposed and…
HbA1C
over 6.5% is diagnostic for diabetes- shows for the past 3 mo…
Diabetes Drugs
Lispro (Humalog)... Aspart (Novolog)
Regular (Humulin R, Novolin R, Regular…
NPH (Humulin N, Novolin N, lente)
Glargine (Lantus)... Detemir (Levemir)
Rapid Acting... Onset: 5-15 min, admin at time of meal... Peak: 60-…
Short Acting... Onset: 30-60 min... Peak: 2-3 hr... Duration: 4-6 hrs…
Intermediate Acting... Onset: 2hr... Peak: 6-8hr... Duration: 12-16hr…
Long Acting... Onset: 1-2hr... Peak: has no peak... Duration: 24+ hrs…
Lispro (Humalog)... Aspart (Novolog)
Rapid Acting... Onset: 5-15 min, admin at time of meal... Peak: 60-…
Regular (Humulin R, Novolin R, Regular…
Short Acting... Onset: 30-60 min... Peak: 2-3 hr... Duration: 4-6 hrs…
Diabetes drugs
Regular insulin (Humulin)
Regular insulin: onset of action (SQ a…
Which type of insulin is most often ad…
Insulin Lispro (Humalog)
Short acting insulin in a Zn solution
30 minutes (must be administered 30-60 before eating)
regular insulin (humulin). when given IV or IM has an onset <…
ultra-short acting insulin that is released very rapidly fr…
Regular insulin (Humulin)
Short acting insulin in a Zn solution
Regular insulin: onset of action (SQ a…
30 minutes (must be administered 30-60 before eating)
42 terms
Diabetes Drugs
biguanide site of action
biguanide desired effect
biguanide side effects
GLP1 agonist site of action
liver, GI, periphery
decreased glucose production;... decreased glucose absorption;... i…
weight loss;... GI upset;... lactic acidosis
liver;... pancreas;... GI;... brain
biguanide site of action
liver, GI, periphery
biguanide desired effect
decreased glucose production;... decreased glucose absorption;... i…
84 terms
Diabetes Drugs
Endogenous Insulin Half-Life
Regular Insulin
Mechanism of Insulin Absorption Delay
NPH Insulin (Neutral Protamine Hagedor…
3-5 minutes
Short acting
Hexamerization
Intermediate acting
Endogenous Insulin Half-Life
3-5 minutes
Regular Insulin
Short acting
12 terms
Diabetes Drugs
Acarbose... class?... action?... benefit?... contr…
Canagliflozin... class?... action?... indicatio…
Exenatide... class?... action?... indication?... c…
Glipizide... class?... action?... indication?... c…
class: alpha glucosidase inhibitor ... action: delayed carb abso…
class: SGLT2 inhibitor... action: block SGLT2 in proximal tubule…
class: incretin... action: GLP-1 receptor agonist which ctrls hy…
class: sulfonylureas ... action: induce release of insulin by in…
Acarbose... class?... action?... benefit?... contr…
class: alpha glucosidase inhibitor ... action: delayed carb abso…
Canagliflozin... class?... action?... indicatio…
class: SGLT2 inhibitor... action: block SGLT2 in proximal tubule…
diabetes drugs
what type of diabetes has the honeymoo…
treatment outline for type 1 diabetes
insulin for type 1 diabetes
rapid acting insulin names
type 1 diabetes
always require insulin... Islet or pancreatic transplantation ... A…
Long acting insulin - basal insulin... rapid acting insulin - b…
lispro, aspart, glulisine
what type of diabetes has the honeymoo…
type 1 diabetes
treatment outline for type 1 diabetes
always require insulin... Islet or pancreatic transplantation ... A…
61 terms
Diabetes drugs
Humulin R
Novolin R
Lispro
Aspart
Regular insulin... Effects after 30 min ... Peak 2-3 hr, lasts 5-8h…
Regular insulin... Effects after 30 min ... Peak 2-3 hr, lasts 5-8h…
Rapid Acting insulin... Humalog... Idential to human insulin excep…
Rapid acting... Novolog... B28 is aspartic acid... reduces self associ…
Humulin R
Regular insulin... Effects after 30 min ... Peak 2-3 hr, lasts 5-8h…
Novolin R
Regular insulin... Effects after 30 min ... Peak 2-3 hr, lasts 5-8h…
62 terms
Diabetes Drugs
What % pts use insulin only?
What % of pts use PO only?
What % of pts use insulin and PO?
Approach to management of DMT2 (picture)
15%
57%
13%
What % pts use insulin only?
15%
What % of pts use PO only?
57%
Diabetes Drugs
What is the MoA of sulphonyluresas
What are the side effects of sulfonylu…
Name some sulfonylureas
You have a patient who is intolerant o…
PROMOTES INSULIN SECRETION... Close ATP sensitive ATP --> influx…
Weight gain, ... HYPOGLYCAEMIA... GI disturbances, N&V, Diarrhoea,…
Tolbutamide, Gliclazide, Glibenclamide
Tolbutamide or Gliclazide
What is the MoA of sulphonyluresas
PROMOTES INSULIN SECRETION... Close ATP sensitive ATP --> influx…
What are the side effects of sulfonylu…
Weight gain, ... HYPOGLYCAEMIA... GI disturbances, N&V, Diarrhoea,…
11 terms
DRUGS FOR DIABETES
glucagon
SULFONYLEUREAS... first gen: diabinese, O…
MEGLITINIDES... repaglinde (Prandin)... nate…
BIGUANIDES... metformin (Glucophage)... Gluc…
hyperglycema agent... emergency for acute hypoglycemia... SQ, IM, I…
help the PANCREAS make extra insulin... take with breakfast... low…
help PANCREAS make extra insulin... take 15-30 min before each m…
stop the LIVER from making extra sugar when not needed... low ri…
glucagon
hyperglycema agent... emergency for acute hypoglycemia... SQ, IM, I…
SULFONYLEUREAS... first gen: diabinese, O…
help the PANCREAS make extra insulin... take with breakfast... low…
82 terms
Diabetes Drugs
Which type of Diabetes is treated sole…
Which type of Diabetes is treated most…
Which insulin is used to treat ketoaci…
What are the differences between Type…
Type I diabetes mellitus (insulin dependent diabetics / juven…
Type II diabetes... - try to decrease insulin resistance ... - most…
regular insulin
Type I: Beta cells are destroyed with no production of insuli…
Which type of Diabetes is treated sole…
Type I diabetes mellitus (insulin dependent diabetics / juven…
Which type of Diabetes is treated most…
Type II diabetes... - try to decrease insulin resistance ... - most…
Diabetes Drugs
Generic name: Metformin... Class: Biguan…
no
no
if the med is taken with food and if t…
Provide the following for Glucophage: ... Generic name: ... Class:…
does metformin cause weight gain?
does metformin cause marked hypoglycemia?
how can the adverse GI effects of metformin be alleviated?
Generic name: Metformin... Class: Biguan…
Provide the following for Glucophage: ... Generic name: ... Class:…
no
does metformin cause weight gain?
Drugs for Diabetes +
Insulin
Chlorpropamide
Tolbutamide
Glimepiride
Diabetes... Type 1
Inhibits ATP sensitive K+ channels ... Diabetes... Type 2... A Sulfony…
Inhibits ATP sensitive K+ channels ... Diabetes... Type 2... A Sulfony…
Inhibits ATP sensitive K+ channels ... Diabetes... Type 2... A Sulfony…
Insulin
Diabetes... Type 1
Chlorpropamide
Inhibits ATP sensitive K+ channels ... Diabetes... Type 2... A Sulfony…
Diabetes drugs
Diabetes mellitus Type 2
Rapid insulin
Insulin aspart
Insulin lispro
Decreased insulin activity / sensitivity
5-15 min onset... short duration... ALG
Rapid acting insulin
Rapid acting insulin
Diabetes mellitus Type 2
Decreased insulin activity / sensitivity
Rapid insulin
5-15 min onset... short duration... ALG
Diabetes: The Drugs
Sulfonylureas - MoA
Sulfonylureas - AE/CI
Sulfonylureas - Drug Examples, their s…
Meglinitides - MoA
Lowers A1c 1-2%... Stimulates B-cells to release insulin... Increas…
Weight gain, hypoglycemia, cardiovascular deaths... Avoid in su…
CYP2C9 Substrates... Diabinese (chlorpropamide)**... Diabeta (glyb…
Lowers A1c 1-1.5%... Stimulate B-Cell insulin release
Sulfonylureas - MoA
Lowers A1c 1-2%... Stimulates B-cells to release insulin... Increas…
Sulfonylureas - AE/CI
Weight gain, hypoglycemia, cardiovascular deaths... Avoid in su…
1 of 10