Study sets matching "heme onc"

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Study sets matching "heme onc"

43 terms
Heme/Onc
Hgb Types
Pancoast Tumor - Type/Symp/Mets Loc
Brain Mets - Tx
Macrocytic Anemia - Drugs that cause/Tx
• HgA - Normal A2B2... • HgA2 - A2D2... • Thalassemia... o Alpha - 1)…
• Usually NSCLC... • Symp- Shoulder pain, Horner(Ptosis, Miosis,…
Brain Mets - Tx
• Drugs - Bactrim, MTX, Phenytoin ... - Tx Folinic Acid
Hgb Types
• HgA - Normal A2B2... • HgA2 - A2D2... • Thalassemia... o Alpha - 1)…
Pancoast Tumor - Type/Symp/Mets Loc
• Usually NSCLC... • Symp- Shoulder pain, Horner(Ptosis, Miosis,…
Heme/Onc
CHOP therapy
HAMs test is positive for
Glanzmans thrombasthenia
Bernard Soullier
prednisone, vincristine, doxorubicin, cyclophosphomide
PNH
deficiency in GPIIb-IIIa
deficiency in GPIb-IX
CHOP therapy
prednisone, vincristine, doxorubicin, cyclophosphomide
HAMs test is positive for
PNH
55 terms
Anemia 1, Heme/Onc
If hemoglobin, hemeatocrit is low, you…
RBC development
RBC life span
HbA, stands for, components
transfuse no matter the cause, always
Nucleated in bone marrow, into circulation they lose the nucl…
120 days
hemoglobin A, 2 alpha and 2 beta globulins
If hemoglobin, hemeatocrit is low, you…
transfuse no matter the cause, always
RBC development
Nucleated in bone marrow, into circulation they lose the nucl…
Heme/Onc
Acanthocyte (spur cell)
Basophilic stippling
Bite cell
Ringed Sideroblast
Liver Failure, abetalipoproteinemia
Anemia of Chronic Disease... alcohol abuse... Lead poisoning
G6PD
Sideroblastic anemia- Excess iron in mitochondria from lead p…
Acanthocyte (spur cell)
Liver Failure, abetalipoproteinemia
Basophilic stippling
Anemia of Chronic Disease... alcohol abuse... Lead poisoning
152 terms
heme-onc
packed RBCs
FFP
Cryoprecipitate
blood transfusion risks
increased Hb, O2 carrying capacity
increased coagulation factor levels
fibrinogen, factor 8, factor 13, vWF, fibronectin; use for he…
Fe overload, hypocalcemia, hyperkalemia
packed RBCs
increased Hb, O2 carrying capacity
FFP
increased coagulation factor levels
heme/onc
heparin
enoxaprin, dalteparin
argtroban, bivalirudin
warfarin
cofactor for activation of antithrombin, decrease thombin and…
low molecular weight heparins, act more on factor Xa, have be…
derviatives of hirudin, the anticoagulant used by leeches, in…
interferes with normal synthesis of gamma-carboxylationg of v…
heparin
cofactor for activation of antithrombin, decrease thombin and…
enoxaprin, dalteparin
low molecular weight heparins, act more on factor Xa, have be…
Heme/Onc
Small lymphocytic Lymphoma
Follicular Small Cleaved
Follicular Mixed
Follicular Large Cell
Diffuse well-differentiated lymphocytic
Nodular poorly differentiated lymphocytic
Nodular mixed lymphocytic- histiocytic
Nodular Histiocytic
Small lymphocytic Lymphoma
Diffuse well-differentiated lymphocytic
Follicular Small Cleaved
Nodular poorly differentiated lymphocytic
43 terms
Heme/Onc
Causes of microcytic anemia:
beta-thalassemia minor:
beta-thalassemia major:
lead poisoning:
iron deficiency, chronic disease (late), thalassemia, lead po…
asymptomatic; increased HbA2 (5%) on electrophoresis
beta chain absent, severe anemia; marrow expansion leads to c…
microcytic anemia; inhibits ferrochelatase and ALA dehydratas…
Causes of microcytic anemia:
iron deficiency, chronic disease (late), thalassemia, lead po…
beta-thalassemia minor:
asymptomatic; increased HbA2 (5%) on electrophoresis
83 terms
Heme-Onc
Neutrophil granules
Major basic protein
Causes of eosinophilia
Drug Reaction with Eosinophilia and Sy…
Specific: ALP, collagenase, lysozyme, lactoferrin... Azurophili…
A helminthotoxin produced by eosinophils
NAACP... Neoplasia... Addison disease (chronic adrenal insufficienc…
2-8 weeks post drug exposure. MOA unknown... Anticonvulsants, al…
Neutrophil granules
Specific: ALP, collagenase, lysozyme, lactoferrin... Azurophili…
Major basic protein
A helminthotoxin produced by eosinophils
15 terms
Heme/Onc
Hereditary Spherocytosis
Unfractionated Heparin vs Enoxaparin/X…
Carboxyhemoglobinemia
Factor V Leiden Mechanism
Coombs-... Dx: acidified glycerol lysis test... AD mutation: ankyri…
Unfractionated better for renal insufficiency
Shifts O2 curve left... Tissue hypoxia increases EPO -> secondar…
unable to respond to protein C
Hereditary Spherocytosis
Coombs-... Dx: acidified glycerol lysis test... AD mutation: ankyri…
Unfractionated Heparin vs Enoxaparin/X…
Unfractionated better for renal insufficiency
62 terms
Heme/Onc
Contents to neutrophil specific granul…
Contents of neutrophil azurophilic gra…
Causes for eosinophilia (5)
3 things bradykinin does
ALP, collagenase, lysozyme, lactoferrin
proteinases, acid phosphatase, MPO, beta-glucuronidase
Neoplasia, Asthma, Allergic processes, Chronic adrenal insuff…
Increases vasodilation, bv permeability, and pain
Contents to neutrophil specific granul…
ALP, collagenase, lysozyme, lactoferrin
Contents of neutrophil azurophilic gra…
proteinases, acid phosphatase, MPO, beta-glucuronidase
87 terms
Heme-Onc-MSK Drugs
cyclophosphamide
Why hemorrhagic cystitis in cyclophaos…
How do we prevent hemorrhagic cystitis?
carboplatin
alkylating agent (nitrogen mustard)... MOA: Covalently X-link (…
Acrolein is metabolite that is toxic to bladder... -attaches t…
Vigrorous hydration... MESNA - sulfhydral binds acrolein to fo…
alkylating agent (platinum analog)... MOA: *covalently bind puri…
cyclophosphamide
alkylating agent (nitrogen mustard)... MOA: Covalently X-link (…
Why hemorrhagic cystitis in cyclophaos…
Acrolein is metabolite that is toxic to bladder... -attaches t…
36 terms
Heme/Onc
MCV <80... Dec Fe... Dec TIBC
MCV <80... Dec Fe... Inc TIBC
MCV <80... Fe normal... TIBC normal/dec
MCV >100... dec retics... inc homocysteine... n…
Anemia of chronic disease
Iron deficiency anemia
Lead poisoning... Thalassemia
Folic acid deficiency
MCV <80... Dec Fe... Dec TIBC
Anemia of chronic disease
MCV <80... Dec Fe... Inc TIBC
Iron deficiency anemia
11 terms
Heme/Onc
ALL
AML (M7 type assd with trisomy 21)
Hodgkin's lymphoma
Neuroblastoma
Fever, pallor, petechiae... Bone pain, refusal to bear weight... Ly…
Patient with trisomy 21... Fever, pallor, petechiae... Gum hyperpla…
Fever, weight loss, night sweats... Normal labs except elevated…
Ill-appearing child... Bone pain, fevers... Blue/purple eyelid disc…
ALL
Fever, pallor, petechiae... Bone pain, refusal to bear weight... Ly…
AML (M7 type assd with trisomy 21)
Patient with trisomy 21... Fever, pallor, petechiae... Gum hyperpla…
10 terms
Heme/Onc
Doxorubicin toxicities
Bleomycin toxicities
Vinblastine toxicities
dacarbazine toxicities
cardiotoxicity, myelosuppression, vesicant, alopecia, red/ora…
pulmonary fibrosis
neurotoxicity, constipation, vesicant
myelosuppression... n/v
Doxorubicin toxicities
cardiotoxicity, myelosuppression, vesicant, alopecia, red/ora…
Bleomycin toxicities
pulmonary fibrosis
58 terms
Heme/Onc
nontender lymphad... +/- B symptoms
Lymphoma w/u
Lymphoma staging
Chemo peripheral neuropathy
Lymphoma
1. excisional bx of LN... - Nothing (fungus/Tb/bacteria)... - met... I…
CXR -> CT or Pet (bx for mets)... S1 1LN... S2 >=2LN not cross diap…
vincristine/vinblastin
nontender lymphad... +/- B symptoms
Lymphoma
Lymphoma w/u
1. excisional bx of LN... - Nothing (fungus/Tb/bacteria)... - met... I…
68 terms
heme/onc
methotrexate mech
methotrexate use
methotrexate tox
5-fu mech
folic acid analog, inhib DHF reductase. dec dTMP, dec DNA, de…
leukemia, lymphoma, choriocarcinoma, sarcoma. Abortion, ectop…
myelosupression, reversible with leucovorin (folinic acid). M…
pyrimadine analog, bioactivated to 5f-dUMP which bonds folic…
methotrexate mech
folic acid analog, inhib DHF reductase. dec dTMP, dec DNA, de…
methotrexate use
leukemia, lymphoma, choriocarcinoma, sarcoma. Abortion, ectop…
heme/onc
teardorp RBC
sickle cell and hotel jolly bodies, au…
spoon nails
alcoholic
myelofibrois
spleen
iron deficiency anemia
folate deficiency
teardorp RBC
myelofibrois
sickle cell and hotel jolly bodies, au…
spleen
Heme/onc
Glanzmans thrombasthenia
Bernard soulier syn
Storage pool dz
Thrombotic microangiopathy
Plt prob. Lack fibrinogen receptors,Plt gp2b3a. Sx mucocutane…
Lack vWF receptors. Sx mucocutaneous bleed. Dx thrombocytopen…
Defective Plt granule secretion, esp ADP. Sx mild dx-inc brui…
Causes: TTP, HUS, DIC, tumor, immune rxn. Leads to organ dysf…
Glanzmans thrombasthenia
Plt prob. Lack fibrinogen receptors,Plt gp2b3a. Sx mucocutane…
Bernard soulier syn
Lack vWF receptors. Sx mucocutaneous bleed. Dx thrombocytopen…
175 terms
heme-onc
heinz bodies seen in
microcytic target cells in
basphilic stippling can be 2/2
side effect of steroid use
G6PD... formed from oxidation of hemoglobin ... G6PD creates NADPH,…
thalassemia minor
lead poisoning (microcytic)... alcholism... thalassemias... its non sp…
inc hematocrit... gynecomastia... hepatotoxicity... dyslipidemia (inc…
heinz bodies seen in
G6PD... formed from oxidation of hemoglobin ... G6PD creates NADPH,…
microcytic target cells in
thalassemia minor
Heme/Onc
Hodgkin Lymphoma
Burkitt Lymphoma (NHL)
Diffuse Large B-cell Lymphoma (NHL)
Follicular Lymphoma (NHL)
Reed-Sternberg Cells (owl eye)... CD15 and CD30+
t(8;14) = c-myc;heavy chain Ig... Starry sky appearance... Tingible…
Bcl-2/6 alterations... Usually older adults... MC NHL in adults
t(14;18) = heavy-chain Ig;BCL-2... Adults... Indolent... Waxing and wa…
Hodgkin Lymphoma
Reed-Sternberg Cells (owl eye)... CD15 and CD30+
Burkitt Lymphoma (NHL)
t(8;14) = c-myc;heavy chain Ig... Starry sky appearance... Tingible…
7 terms
Heme/Onc
Binds and activates ATIII--> inactivat…
Binds to ATIII--> inactivates Xa (no e…
1) Protamine sulfate (give slowly to p…
INR <5+no sig bleeding: lower or omit…
How dose heparin work?... How do you monitor it?
How dose lovenox work?... How do you monitor it?
How do you reverse:... 1) heparin... 2) Lovenox... 3) Coumadin
What do you do with certain INRs/bleeding scenarios when on c…
Binds and activates ATIII--> inactivat…
How dose heparin work?... How do you monitor it?
Binds to ATIII--> inactivates Xa (no e…
How dose lovenox work?... How do you monitor it?
38 terms
Heme/Onc
Pernicious Anemia
Anemia of Chronic Disease
Direct Coombs Test
Spinal cord compression
auto-Abs against intrinsic factor... Dx w/ anti-IF Abs... Most comm…
-Tx = Epo... -Ensure adequate Fe stores bc RBCs are production i…
Abs are attached to RBCs
1. IV glucocorticoids... 2. MRI
Pernicious Anemia
auto-Abs against intrinsic factor... Dx w/ anti-IF Abs... Most comm…
Anemia of Chronic Disease
-Tx = Epo... -Ensure adequate Fe stores bc RBCs are production i…
111 terms
Heme/Onc
what causes hypersegmented neutrophils
how do eosinphils kill helminths
chronic adrenal insufficiency causes o…
what cell contains heparin?
B12 (necessary for folate recycling) or folate def
major basic protein
eosinophils
basophils
what causes hypersegmented neutrophils
B12 (necessary for folate recycling) or folate def
how do eosinphils kill helminths
major basic protein
6 terms
Heme/Onc
Microcytic Anemia, hypochromic (MCV<80)
Macrocytic anemia, MCV>100
Nonhemolytic, normocytic anemia
Intrinsic Hemolytic, normocytic anemia
-Iron deficiency... -alpha-thalassemia... -Beta-thalassemia... -lead p…
-megaloblastic anemia... -folate deficiency... -B12 deficiency... -oro…
-anemia of chronic disease... -aplastic anemia
-Hereditary spherocytosis... -G6PD deficiency... -Pyruvate kinase d…
Microcytic Anemia, hypochromic (MCV<80)
-Iron deficiency... -alpha-thalassemia... -Beta-thalassemia... -lead p…
Macrocytic anemia, MCV>100
-megaloblastic anemia... -folate deficiency... -B12 deficiency... -oro…
30 terms
Heme/Onc
Argatroban, bivalidrudin
Apixaban, rivaroxaban
Alteplase (tPA), reteplase, tenecteplase
Aspirin
Inhibit thrombin directly. Used instead of heparin for antico…
Binds and directly inhibits activity of factor Xa... Increases…
thrombolytics... Directly or indirectly aid conversion of plasm…
Irreversibly inhibits cyclooxygenase (both COX1 and COX 2) en…
Argatroban, bivalidrudin
Inhibit thrombin directly. Used instead of heparin for antico…
Apixaban, rivaroxaban
Binds and directly inhibits activity of factor Xa... Increases…
11 terms
Heme/Onc
Acute Intermittent Porphorya
Lead Poisoning
Porphyria cutanea tarda
Platelet Disorders
Precipitated by drugs, alcohol, starvation... Affected: Porphobi…
Affected: Ferrocheletase (incorporates Iron into Protoporphyr…
Defect in Urobilinogen Decarboxylase. Buildup of Uroporphyrin…
Bleeding time increased. Platelet abnormalities --> micro hem…
Acute Intermittent Porphorya
Precipitated by drugs, alcohol, starvation... Affected: Porphobi…
Lead Poisoning
Affected: Ferrocheletase (incorporates Iron into Protoporphyr…
226 terms
Heme/Onc
erythrocytosis
anisocytosis
poikilocytosis
reticulocyte
polycythemia= increased hematocrit (increased RBC mass)
varying sizes of RBCs
varying shapes of RBCs
immature erythrocyte, marker of erythroid proliferation
erythrocytosis
polycythemia= increased hematocrit (increased RBC mass)
anisocytosis
varying sizes of RBCs
HEME/ONC
Anemia S&S
Anemia Dx
Anemia Complications
Blood Transfusion Reactions
Decrease in hgb or RBC, and NOT inadequate... -fatigue/headache…
H&P... CBC... MCV, MCH... Pt energy and activity levels
-Infection... -Need for transfusion... -HF
Hemolytic: headache, chills, flank pain, N/V, shaking, DIC si…
Anemia S&S
Decrease in hgb or RBC, and NOT inadequate... -fatigue/headache…
Anemia Dx
H&P... CBC... MCV, MCH... Pt energy and activity levels
93 terms
Heme/Onc
Anemia Compensation
Cryoprecipitate
FFP
Intravascular hemolysis- transfusion
Increased CO (HR and SV)... Increased extraction ratio... Right shi…
Contains factor 8 and fibrinogen... Give for Hemophilia A, decre…
Contains all clotting factors... Give for high PT/PTT, coagulopa…
Acute hemolytic transfusion reactions... ABO-mismatched blood- w…
Anemia Compensation
Increased CO (HR and SV)... Increased extraction ratio... Right shi…
Cryoprecipitate
Contains factor 8 and fibrinogen... Give for Hemophilia A, decre…
heme/onc
content of dense granules
content of alpha granules
petechiae
poikilocytosis
calcium, ADP
vWF, fibrinogen
result of thrombocytopenia
varying shapes (RBCs)
content of dense granules
calcium, ADP
content of alpha granules
vWF, fibrinogen
116 terms
Heme/onc
large granular lymphocyte (LGL)
the most common malignancy-related cau…
Bisphosphonates are powerful inhibitor…
most appropriate for this patient with…
Felty syndrome
Metastatic tumors originating from lung cancer and cutaneous…
osteoclast-mediated bone resorption
leucovorin, 5-fluorouracil, and oxaliplatin (FOLFOX)
large granular lymphocyte (LGL)
Felty syndrome
the most common malignancy-related cau…
Metastatic tumors originating from lung cancer and cutaneous…
27 terms
Heme/onc
Dx tests for breast cancer
Breast utz
Autoimmune hemolysis
Cold agglutinin disease
FNA- best initial biopsy; small sample... CNB- large sample; de…
Distinguishes cysts from solid lesions; perform when it's pai…
Microspherocytes; warm IgG... Most accurate test- Coombs test... T…
IgM against EBV, waldenstrom macroglobulinemia, mycoplasma pn…
Dx tests for breast cancer
FNA- best initial biopsy; small sample... CNB- large sample; de…
Breast utz
Distinguishes cysts from solid lesions; perform when it's pai…
124 terms
Heme/Onc
RBC membrane antiporter
Platelet vWF receptor
Platelet fibrinogen receptor
Macrophage surface marker
HCO3-/Cl-
GpIb
GpIIb/IIIa
CD14
RBC membrane antiporter
HCO3-/Cl-
Platelet vWF receptor
GpIb
18 terms
Heme Onc
Squamous cell Carcinoma triad of sx
Lymphoproliferative Disorder sx
Differntiate blood transfusion problem…
Sideroblastic ianemia diagnosis?
Firm Solitary Nodule + Non-Tender Neck + Smoking Hx = Squamou…
Enlarged LN multiple places + Hepatosplenomegaly + Anemia + F…
Acute Hemolytic = ABO badness, ab are made = 1 hour; FLANK PA…
4037 Isoniazid = B6 deficiency = automatically sideroblatic a…
Squamous cell Carcinoma triad of sx
Firm Solitary Nodule + Non-Tender Neck + Smoking Hx = Squamou…
Lymphoproliferative Disorder sx
Enlarged LN multiple places + Hepatosplenomegaly + Anemia + F…
heme-onc
as a nurse you need to think about wha…
CF patients get all vaccines and take…
normal newborns Hbg, hct, platelets
most common hematological disorder of…
handwashing
true
hgb-high... hgt-high... platelets-low
anemia. not disease itself, symptoms of underlying disorder
as a nurse you need to think about wha…
handwashing
CF patients get all vaccines and take…
true
78 terms
Heme/Onc
Platelets Normal Range
Platelet Dense Granules
Platelet Alpha Granules
Thrombopoietin
150,000-350,000/microliter
ADP, ATP, serotonin
plasma proteins
TPO... -produced in the liver (a little in the kidney)... -potent m…
Platelets Normal Range
150,000-350,000/microliter
Platelet Dense Granules
ADP, ATP, serotonin
Heme/onc
increased MCHC
DIC is common presentation of what leu…
distinguishes leukemoid reaction form…
cell markers on reed-sternberg
hereditary spherocytosis
AML... see auer rods, increased circulating myeloblasts... associat…
increased leukocyte alkaline phosphatase
CD15 and CD30
increased MCHC
hereditary spherocytosis
DIC is common presentation of what leu…
AML... see auer rods, increased circulating myeloblasts... associat…
164 terms
Heme/Onc
Cl/HCO3 antiporter on RBCs
RBC lifespan
platelet lifespan
ADP, Ca, vWF, fibrinogen
allows for control of blood pH
120 days
8-10 days
contents of platelet granules
Cl/HCO3 antiporter on RBCs
allows for control of blood pH
RBC lifespan
120 days
100 terms
Heme/Onc
Acanthocyte (Spur Cell) - spikey
Burr Cell
Basophilic Stippling... (RNA clumps)
Bite Cells
Liver Disease... Abetalipoproteinemia
Uremia
*Lead poisoning... - alcohol abuse... - thalassemias... - anemia of ch…
G6PD deficiency
Acanthocyte (Spur Cell) - spikey
Liver Disease... Abetalipoproteinemia
Burr Cell
Uremia
30 terms
Heme/Onc
Heparin
Warfarin
enoxaparin
Hemophilia
PTT/intrinsic, antithrombin III,tx- protamine sulfate
PT/extrinsic, (2,7,9,10,C,S), teratogen,tx- vit. K
LMWH, Xa
clotting factors, X-linked-M-+FHx, OR acuired ab (AI, Lymphop…
Heparin
PTT/intrinsic, antithrombin III,tx- protamine sulfate
Warfarin
PT/extrinsic, (2,7,9,10,C,S), teratogen,tx- vit. K
Heme/Onc
MOA of Unfractionated Heparin
MOA of LMWH (Enoxaparin):
Hemophilia A deficiency =
Hemophilia B deficiency =
Activates Antithrombin III, Increases PTT
Factor Xa Inhibitor
Factor VIII
Factor IX
MOA of Unfractionated Heparin
Activates Antithrombin III, Increases PTT
MOA of LMWH (Enoxaparin):
Factor Xa Inhibitor
197 terms
Heme/Onc
Microcytic Anemias: MCV < 80
Normocytic Anemias: MCV 80-100
Macrocytic Anemia: MCV > 100
Diseases that cause cold agglutinins:
Iron deficiency... Lead poison... Chronic disease... Sideroblastic ane…
Hemolytic... Chronic Disease... Hypovolemia
Folate deficiency... B12 deficiency... Liver disease... Alcohol Abuse
IgM... - Mycoplasma... - EBV
Microcytic Anemias: MCV < 80
Iron deficiency... Lead poison... Chronic disease... Sideroblastic ane…
Normocytic Anemias: MCV 80-100
Hemolytic... Chronic Disease... Hypovolemia
Heme/onc
Schistocytes - helmet cells found in
Patients with hereditary telangiectasi…
The lupus anticoagulant, an anti-phosp…
Negative family history positive Coomb…
DIC, HUS, TTP
pulmonary AVMs w/hemoptysis and right to left shunt physiolog…
prolonged PTT
AIHA - Autoimmune hemolytic anemia
Schistocytes - helmet cells found in
DIC, HUS, TTP
Patients with hereditary telangiectasi…
pulmonary AVMs w/hemoptysis and right to left shunt physiolog…
Heme/Onc
smear of peripheral blood: neutrophils…
anemia
acute anemia
chronic anemia
never let monkeys eat bananas
What is the most common childhood hematologic problem
anemia that presents w/tachycardia, flow murmur, poor exercis…
anemia that is well tolerated in children and present w/tachy…
smear of peripheral blood: neutrophils…
never let monkeys eat bananas
anemia
What is the most common childhood hematologic problem
Heme/Onc
Apixaban
Rivaroxaban
Alteplase (tPA)
Reteplase (rPA)
Direct Factor Xa inhibitor
Direct Factor Xa inhibitor
Thrombolytics, convert plasminogen to plasmin... Toxicity: BLEED…
Thrombolytics, convert plasminogen to plasmin... Toxicity: BLEED…
Apixaban
Direct Factor Xa inhibitor
Rivaroxaban
Direct Factor Xa inhibitor
46 terms
Heme Onc
Apixaban
Tx for thrombolytic tox
Aspirin tox sx
Clopidogrel, ticlodipine
F10a inhib
Aminocaproic acid
Tinnitus, fever, tachypnea
Platelet aggregat. Inhib for acute coronary syndrome and coro…
Apixaban
F10a inhib
Tx for thrombolytic tox
Aminocaproic acid
128 terms
Heme/Onc
Characterization of anemia in Anemia a…
Characterization of iron deficiency an…
Reticulocyte cellular hemoglobin (CHr)
Soluble transferrin receptor (sTfR)
normocytic, normochromic. Characterized by normal size and he…
microcytic and hypochormic
Useful for the early detection of iron restriction to the ery…
Produced when erythroblasts become fully hemoglobinized and s…
Characterization of anemia in Anemia a…
normocytic, normochromic. Characterized by normal size and he…
Characterization of iron deficiency an…
microcytic and hypochormic
6 terms
Heme/Onc
WBC and Differential
Causes of Eosinophilia
Vitamin K-dependent factors
Anti-thrombin inhibits...
nl = 4000-10,000 cells/mm3... Neutrophils (54-62%)... Lymphocytes…
"worms, wheezes, and weird diseases" ... Neoplasia... Asthma... Allerg…
II, VII, IX, X... protein C, protein S
thrombin, Xa... (activated forms of II, VII, IX, X, XI, XII)
WBC and Differential
nl = 4000-10,000 cells/mm3... Neutrophils (54-62%)... Lymphocytes…
Causes of Eosinophilia
"worms, wheezes, and weird diseases" ... Neoplasia... Asthma... Allerg…
38 terms
HEME-ONC
ALL PEAK AGE
ALL CLIN, LABS
ALL XRAY "leukemic lines"
ALL STANDARD RISK (75-90% survival)
4yo
fever, pallor/bleeding (anemia/thrombocytopenia in 90%), LAN,…
at metaphyses
age b/w 1-10yo, WBC at dx <50K, no prior steroids, no CNS/tes…
ALL PEAK AGE
4yo
ALL CLIN, LABS
fever, pallor/bleeding (anemia/thrombocytopenia in 90%), LAN,…
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