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Study sets matching "hiv aids micro"

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Study sets matching "hiv aids micro"

30 terms
HIV AIDS
disease
virus
factory
bursts
A _______________is an illness or condition that keeps your b…
A _________________is a tiny particle that can reproduce only…
The cell acts like a __________making copies of the virus
When the cell is full, it ___________ and new viruses spill o…
disease
A _______________is an illness or condition that keeps your b…
virus
A _________________is a tiny particle that can reproduce only…
18 terms
HIV and AIDS
HIV
AIDS
HIV
AIDS
abbreviation for the human immunodeficiency virus
abbreviation for the acquired immune deficiency syndrome
the virus that causes acquired immune deficiency syndrome
can result from HIV; the immune system is weakened and diseas…
HIV
abbreviation for the human immunodeficiency virus
AIDS
abbreviation for the acquired immune deficiency syndrome
15 terms
HIV AIDS
Hiv
extramembrane
transmembrane
delayed (false negative TB test)
what dis?
GP41 is extra-membrane receptor or transmembrane?
GP120 is extra-membrane receptor or transmembrane?
what will happen to hypersensitivity in infection of people w…
Hiv
what dis?
extramembrane
GP41 is extra-membrane receptor or transmembrane?
24 terms
HIV / AIDS
Global Burden
ART/ARVs/HAART
Investigations*
PrEP*
>39 million deaths so far, 39 million people living with HIV.…
5 classes: Nucleoside/tide analog RTIs, Non Nucleoside analog…
Antibody tests- ELISA, Western blot confirms, Antigen tests-p…
...
Global Burden
>39 million deaths so far, 39 million people living with HIV.…
ART/ARVs/HAART
5 classes: Nucleoside/tide analog RTIs, Non Nucleoside analog…
17 terms
HIV/AIDS
HIV structure
HIV Life Cycle
acute HIV infection
spread of the virus
2 identical strands of RNA with associated enzymes within a c…
viral glycoproteins bind to CD4+ T helper cells, macrophages…
> 80% of HIV transmission occurs in mucosal surfaces... transmi…
3-6 days - spreads beyond submucosal cells and goes to the LN…
HIV structure
2 identical strands of RNA with associated enzymes within a c…
HIV Life Cycle
viral glycoproteins bind to CD4+ T helper cells, macrophages…
12 terms
HIV/AIDS
HIV
Characteristics
Aciton
Symtpoms
Retrovirus... Highjacks other cells... Converts RNA to DNA (revers…
HIV prefers the T helper cell... which are key to Immune system…
BINDS to CD4 receptor ... ENTERS cell... RNA - DNA ... NEW HIV cell…
2-4 after infection FLU like symptoms ... LYMPHADENOPATHY... THROM…
HIV
Retrovirus... Highjacks other cells... Converts RNA to DNA (revers…
Characteristics
HIV prefers the T helper cell... which are key to Immune system…
36 terms
HIV/AIDS
HIV/AIDS
HIV
HIV Transmission
People most at risk for HIV infection
Human Immunodeficiency Virus... -Preferentially attacks CD4+ T-c…
RNA retrovirus ... -HIV-1: United States... -HIV-2: Developing coun…
Body fluids capable of transmitting HIV ... -Blood... -Semen... -Cervi…
People who participate in....... -Male-Male sexual contact... -Inje…
HIV/AIDS
Human Immunodeficiency Virus... -Preferentially attacks CD4+ T-c…
HIV
RNA retrovirus ... -HIV-1: United States... -HIV-2: Developing coun…
47 terms
HIV/AIDS
Who is at risk
modes of transmission
Modes of tranmission
viral presence in body fluid
-gay, bisexual, and other men who have sex... -black men and wom…
-vaginal... -anal... -IV blod exposure by sharing needles
-blood tranfusion... -mother to child before or during childbirt…
-blood... -semen... -vaginal fluid... -breast milk
Who is at risk
-gay, bisexual, and other men who have sex... -black men and wom…
modes of transmission
-vaginal... -anal... -IV blod exposure by sharing needles
HIV/AIDS
The nurse is aware that myelosuppressi…
Which of the following statements if m…
test informed HIV in in infant
confirms the presence of HIV antibodies
Decrease in platelet counts
Does not totally eliminate human immunodeficiency virus from…
P 24, virus culture of HIV, or polymerize chain reaction
Western blot test l
The nurse is aware that myelosuppressi…
Decrease in platelet counts
Which of the following statements if m…
Does not totally eliminate human immunodeficiency virus from…
24 terms
HIV/AIDS
Human Immunodeficiency Virus
CD4+ count
Viral Load
AIDS defining illnesses
Retrovirus that targets & destroys CD4+ T lymphocytes. Charac…
Indicates degree of immunosuppression. Guides therapy and p…
Predict rate of disease progression. Provides indications f…
1. Symptomatic HSV infection lasting > 1 month. 2. Esophageal…
Human Immunodeficiency Virus
Retrovirus that targets & destroys CD4+ T lymphocytes. Charac…
CD4+ count
Indicates degree of immunosuppression. Guides therapy and p…
24 terms
HIV/AIDS
Human Immunodeficiency Virus
CD4+ count
Viral Load
AIDS defining illnesses
Retrovirus that targets & destroys CD4+ T lymphocytes. Charac…
Indicates degree of immunosuppression. Guides therapy and p…
Predict rate of disease progression. Provides indications f…
1. Symptomatic HSV infection lasting > 1 month. 2. Esophageal…
Human Immunodeficiency Virus
Retrovirus that targets & destroys CD4+ T lymphocytes. Charac…
CD4+ count
Indicates degree of immunosuppression. Guides therapy and p…
14 terms
HIV/AIDS
What does the acronym stand for and wh…
What is HIV
What is AIDS
What does the acronym stand for and wh…
Human Immunodeficiency Virus.
It is a communicable disease, a virus that enters the body an…
A series of diseases that result from the HIV virus destroyin…
Acquired Immunodeficiency Syndrome.
What does the acronym stand for and wh…
Human Immunodeficiency Virus.
What is HIV
It is a communicable disease, a virus that enters the body an…
44 terms
HIV/AIDS
Poorly functioning CD4+ cell leads to…
with poor functioning CD4+ the pt is a…
what is the requirement to be diagnose…
Can HIV be transmitted at all stages ?
lymphocytopenia ,increase production of incomplete and nonfun…
opportunistic infections (cells that are present and as part…
HIV positive and a CD4+ count less than 200 cell per/mm or le…
YES
Poorly functioning CD4+ cell leads to…
lymphocytopenia ,increase production of incomplete and nonfun…
with poor functioning CD4+ the pt is a…
opportunistic infections (cells that are present and as part…
50 terms
HIV/AIDS
1987 - The FDA approves 1st antiretrov…
1995 - There are now over _______ case…
CD4 cells are often called...
HIV capsid
Zidovudine or AZT
500,000
T-cells or T-helper cells... -White blood cells that play a majo…
-HIV's bullet shaped core that contains HIV RNA
1987 - The FDA approves 1st antiretrov…
Zidovudine or AZT
1995 - There are now over _______ case…
500,000
94 terms
HIV/AIDS
What does HIV stand for?
What is HIV?
When was HIV first discovered?
What part of the immune system does HI…
Human Immunodeficiency Virus
a single-stranded RNA retrovirus that causes AIDS
In the early 1980s
CD4+ Helper T lymphocytes
What does HIV stand for?
Human Immunodeficiency Virus
What is HIV?
a single-stranded RNA retrovirus that causes AIDS
34 terms
HIV/AIDS
What immune cells (and subsets) are in…
What are the three main transmission r…
What is the risk of transmitting AIDS…
What roles do the following play in th…
Primarily infects vital components of the human immune syste…
Sexual Route, Blood or Blood Product Route to include needle…
There has been no documented account of AIDS being transmitte…
The envelope proteins gp120 and gp41 bind to CD4+ cell or mac…
What immune cells (and subsets) are in…
Primarily infects vital components of the human immune syste…
What are the three main transmission r…
Sexual Route, Blood or Blood Product Route to include needle…
46 terms
HIV and AIDS
HIV - Origin and Historical Perspective
HIV Disease causative agent:
HIV Disease Pathogenesis:
HIV Transmission:
Human Immunodeficiency Virus - Acquired ImmunoDeficiency Syn…
- In U.S. disease is caused by human immunodeficiency virus t…
- attacks variety of cell types... Most critical are Helper T-c…
HIV is spread primarily by:... Transference of cells and fluids…
HIV - Origin and Historical Perspective
Human Immunodeficiency Virus - Acquired ImmunoDeficiency Syn…
HIV Disease causative agent:
- In U.S. disease is caused by human immunodeficiency virus t…
71 terms
HIV & AIDS
What are the 5 body fluids that can tr…
What are some examples of body fluids…
Horizontal transmission
Vertical transmission
Blood... Semen, pre-seminal fluid... Rectal secretions... Vaginal secr…
Saliva... Sweat... (antibodies are present in these fluids, but no…
Sexual; heterosexual transmission is the most common in the W…
Mom to child; if the mother's HIV is undetectable at the time…
What are the 5 body fluids that can tr…
Blood... Semen, pre-seminal fluid... Rectal secretions... Vaginal secr…
What are some examples of body fluids…
Saliva... Sweat... (antibodies are present in these fluids, but no…
19 terms
HIV/AIDs
describe the HIV virus
what cell does HIV bind to
how does the HIV virus bind onto the C…
what stages of the HIV lifecycle can b…
- two forms (HIV 1 and 2)... - belong to the lentivirus subfamil…
- CD4
- gp 120 binds to CD4 which causes a conformational change... -…
- attachment and fusion... - reverse transcription... - integration…
describe the HIV virus
- two forms (HIV 1 and 2)... - belong to the lentivirus subfamil…
what cell does HIV bind to
- CD4
28 terms
HIV-AIDS
What are the characteristics of HIV we…
What enzymes does HIV need?
What are the different parts of the HI…
What are the accessory genes of HIV an…
Retroviridea family... Lentivirinae genus... enveloped ssRNA positi…
reverse transcriptase... integrase... aspartyl protease
tat & nef suppress synthesis of MHC class I molecules
What are the characteristics of HIV we…
Retroviridea family... Lentivirinae genus... enveloped ssRNA positi…
What enzymes does HIV need?
reverse transcriptase... integrase... aspartyl protease
28 terms
HIV/ AIDS
what is HIV?
how does the replication of HIV work?
what does HIV primarily target?
what does this lead to?
a retrovirus that has ribonucleic acid (RNA) as its genetic m…
can't replicate itself so needs a host cell to do it via the…
cells in the immune system
low levels of CD4+ T cells
what is HIV?
a retrovirus that has ribonucleic acid (RNA) as its genetic m…
how does the replication of HIV work?
can't replicate itself so needs a host cell to do it via the…
9 terms
HIV and AIDS
HIV
AIDS
AIDS
opportunistic
abbreviation for the human immunodeficiency virusthe virus an…
abbreviation for the acquired immune deficiency syndrome
can result from HIV; the immune system is weakened and diseas…
type of infection that take advantage of a weakened immune sy…
HIV
abbreviation for the human immunodeficiency virusthe virus an…
AIDS
abbreviation for the acquired immune deficiency syndrome
48 terms
HIV/AIDS
Retroviruses
HIV
AIDS
HIV Life Cycle
RNA viruses that reproduces by transcribing its RNA into DNA…
Human Immunodeficiency Virus
Acquired Immunodeficiency Syndrome
Retroviruses
RNA viruses that reproduces by transcribing its RNA into DNA…
HIV
Human Immunodeficiency Virus
18 terms
HIV/AIDS
HIV is a retrovirus. ... What is a retro…
How is HIV infection acquired?
What are risk factors for HIV infection?
Who should be screened for HIV infecti…
Enveloped RNA virus
-Retroviruses use the virally encoded enzyme reverse... transcri…
...
Who? All persons aged 13-64 ... How often? At least once for ev…
HIV is a retrovirus. ... What is a retro…
Enveloped RNA virus
How is HIV infection acquired?
-Retroviruses use the virally encoded enzyme reverse... transcri…
21 terms
HIV/AIDS
Immunosupression... Definition and Who is…
HIV
AIDS
HIV epidemic
the decrease in the ability of the immune system to respond t…
Human Immunodeficiency virus... kills dendritic cells, macropha…
stage 3 of HIV... Acquired Immunodeficiency Syndrome ... Unable t…
currently no FDA approved vaccine ... directly attacks the immu…
Immunosupression... Definition and Who is…
the decrease in the ability of the immune system to respond t…
HIV
Human Immunodeficiency virus... kills dendritic cells, macropha…
11 terms
HIV/AIDS
HIV AIDS Patients are susceptible to
Mycobacterium Avium Complex (MAC)
Cryptococcus Neoformans
Cryptococcus Neoformans Pathogenesis
-Mycobacterium Avium Complex... -Cryptococcus... -Histoplasmosis... -C…
Is an atypical bacterium found in the environment (food, wate…
- Pathogenic fungi w/ a polysaccharide polymer capsule... - The…
Infectious spores in the environment get inhaled and then rea…
HIV AIDS Patients are susceptible to
-Mycobacterium Avium Complex... -Cryptococcus... -Histoplasmosis... -C…
Mycobacterium Avium Complex (MAC)
Is an atypical bacterium found in the environment (food, wate…
12 terms
HIV/AIDS
HIV transmission occurs through which…
Risk Factors for HIV
Routine HIV Testing
Additional HIV testing on should be do…
Blood... Ejaculate/Pre-ejaculate... Vaginal Secretions... Breast Milk
Any unprotected sex... Multiple partner/anonymous... Other STIs... Sha…
ages 15-64
Tested and treated for STIs... Initiating TB ... Pregnant Women... Wom…
HIV transmission occurs through which…
Blood... Ejaculate/Pre-ejaculate... Vaginal Secretions... Breast Milk
Risk Factors for HIV
Any unprotected sex... Multiple partner/anonymous... Other STIs... Sha…
24 terms
HIV/AIDS
Primary immunodeficiency diseases
Acquired (secondary) immunodeficiency…
HIV -An enveloped positive single-st…
HIV -is characterized by glycoproteins…
Result from some genetic or developmental defect. Detectable…
Developed later in life as a direct consequence of some other…
Primary immunodeficiency diseases
Result from some genetic or developmental defect. Detectable…
Acquired (secondary) immunodeficiency…
Developed later in life as a direct consequence of some other…
45 terms
HIV/AIDs
History of HIV/AIDs
HIV description
Virus structure
Pathophysiology
o Initially arose in 1981 in LA - affected gay men (& hemophi…
o Lentivirus (subgroup of retroviruses)... o 120nm (60x smalle…
o ssRNA tightly bound to nucleocapsid proteins, p7, and enz…
o Lacking ligands/receptors leads to immunity ... o Viruses atta…
History of HIV/AIDs
o Initially arose in 1981 in LA - affected gay men (& hemophi…
HIV description
o Lentivirus (subgroup of retroviruses)... o 120nm (60x smalle…
13 terms
HIV/AIDS
stability
doubt
taboo
mosque
N. OPP = instability... ổn định, hằng định... - The political ---—-…
N... sự nghi ngờ, hoài nghi... -There is no ---- that social and re…
ADJ... kiêng kỵ, cấm kỵ... - Community leaders could not treat it a…
N... nhà thờ Hồi giáo
stability
N. OPP = instability... ổn định, hằng định... - The political ---—-…
doubt
N... sự nghi ngờ, hoài nghi... -There is no ---- that social and re…
56 terms
HIV/AIDS
HIV vs. AIDS
Where is most HIV found?
US Epidemic of HIV
HIV in Indiana
HIV - a retrovirus that infects primarily CD4+ T helper cells…
Sub-Saharan Africa 24.7 million... Total is 35million
- CDC estimates more than 1.2 million people are living with…
- Marion county has highest incidence (235) and prevalence (4…
HIV vs. AIDS
HIV - a retrovirus that infects primarily CD4+ T helper cells…
Where is most HIV found?
Sub-Saharan Africa 24.7 million... Total is 35million
35 terms
HIV & AIDS
History
Disease Process
Acute Seroconversion
Seroconversion
1981... -first published report in morbidity and mortality world…
-AIDS is a disease where the HI virus debilitates the host's…
-2-4 weeks - 3 months... -1/2 to 2/3 will get this... -severe flu o…
-6 weeks - 6 months after exposure... *positive blood test... -dorm…
History
1981... -first published report in morbidity and mortality world…
Disease Process
-AIDS is a disease where the HI virus debilitates the host's…
96 terms
HIV/AIDS
Stages of HIV infection
Outliers
AIDS-defining illnesses
Early Clinical Presentation
Viral transmission... Primary HIV infection (PHI)... Seroconversion…
Long-term non-progressors (CD4 > 500)... Elite controllers (keep…
Bacterial infections... Candidiasis... Cervical cancer... Coccidioidom…
Fever... Fatigue... Myalgia... Rash ... HA... Pharyngitis... Cervical adenopath…
Stages of HIV infection
Viral transmission... Primary HIV infection (PHI)... Seroconversion…
Outliers
Long-term non-progressors (CD4 > 500)... Elite controllers (keep…
29 terms
HIV/AIDS
CD4+ Count in AIDS
CD4+/CD8+ Ratio
Skin Manifestations AIDS
Respiratory Manifestations AIDS
less than 200/mm3
less than 2 (<2)
-dry skin... -poor wound healing... -skin lesions... -night sweats
-shortness of breath... -cough
CD4+ Count in AIDS
less than 200/mm3
CD4+/CD8+ Ratio
less than 2 (<2)
9 terms
HIV/AIDS
Saquinavir (Invirase)
Stavudine
Pentam
Zidovudine (AZT, Retrovir)
Used for HIV PT. teaching includes, Avoid sun exposure, eat h…
Used for HIV assess for Paresthesia is abnormal sensation tin…
Use for pneumocystis jiroveci pneumonia check for anemia and…
For HIV, check CBC, fatigue, vomiting, hyperventilation
Saquinavir (Invirase)
Used for HIV PT. teaching includes, Avoid sun exposure, eat h…
Stavudine
Used for HIV assess for Paresthesia is abnormal sensation tin…
62 terms
HIV/AIDS
AIDS
CD4 protein
CD4+ cells
HAART
Acquired Immunodeficiency Syndrome. An immunodeficiency cause…
A cell-surface protein found on some T-cells, monocytes, macr…
Cells that express the CD4 protein on their surface. Predomin…
Highly Active Antiretroviral Therapy. A combination of drugs…
AIDS
Acquired Immunodeficiency Syndrome. An immunodeficiency cause…
CD4 protein
A cell-surface protein found on some T-cells, monocytes, macr…
9 terms
HIV / AIDS
HIV
AIDS
T Cells
HIV Treatment
Human Immunodeficiency Virus
Acquired Immune Deficiency Syndrome
An immune system cell that coordinates the immune system and…
Anti Viral Medications
HIV
Human Immunodeficiency Virus
AIDS
Acquired Immune Deficiency Syndrome
11 terms
HIV/AIDS
What is HIV/AIDS
How is HIV/AIDS transmitted
Causes of HIV/AIDS
HIV/AIDS global statistics
- A communicable disease that destroys the white blood cells…
- Unprotected sex with another infected person ... - Sharing a…
- Lack of education on disease... - Poverty leading to lack of…
- Identified in every country in the world... - 39 million are…
What is HIV/AIDS
- A communicable disease that destroys the white blood cells…
How is HIV/AIDS transmitted
- Unprotected sex with another infected person ... - Sharing a…
23 terms
HIV & AIDS (lecture 26)
Define lentivirus
How long (typically) after infection d…
How is the virus transmitted?
when were the first cases observed?
a slow acting virus
5-10 years
through the exchange of bodily fluids (blood, semen and breas…
around 1979
Define lentivirus
a slow acting virus
How long (typically) after infection d…
5-10 years
12 terms
HIV/AIDS
HIV
AIDS
3 ways the disease spreads
T Cell
the virus the causes AIDS
the disease that interferes with the bodies ability to fight…
sexual intercourse, using contaminated needles, and pregnancy
coordinate the body's response to infection
HIV
the virus the causes AIDS
AIDS
the disease that interferes with the bodies ability to fight…
29 terms
HIV/AIDS
Acquired. _____ _____ _____
HIV (Human Immunodeficiency Virus)
HIV-1
HIV-2
Immune. Deficiency. Syndrome.
causes AIDS
most common
less common, less virulent/severe
Acquired. _____ _____ _____
Immune. Deficiency. Syndrome.
HIV (Human Immunodeficiency Virus)
causes AIDS
39 terms
HIV/AIDs
3 ways HIV/AIDs is transmitted
HIV trend in US
HIV diagnositic testing algorithm
HIV/AIDs prevalence in gender
blood products- transfusion, sharing needles, needlesticsk... bo…
despite public health efforts, 50-60k new infections yearly... m…
2:1 males to females
3 ways HIV/AIDs is transmitted
blood products- transfusion, sharing needles, needlesticsk... bo…
HIV trend in US
despite public health efforts, 50-60k new infections yearly... m…
HIV/AIDS
non rapid HIV test
western blot
primary HIV
HIV asymptomatic
if positive, repeat then Western blot
confirmatory HIV test
occurs from time of infection to replication of antibodies
stage of HIV where CD4 & T lymphocyte 500 +; usually last 6 m…
non rapid HIV test
if positive, repeat then Western blot
western blot
confirmatory HIV test
59 terms
HIV/AIDS
HIV
AIDS
Normal T-Cell Count
Low T-Cell Count
Human immunodeficiency Virus
Acquired Immune Deficiency Syndrome
800-1200
650-800
HIV
Human immunodeficiency Virus
AIDS
Acquired Immune Deficiency Syndrome
25 terms
HIV/AIDS
HIV Routes of Transmission
Pathophysiology of HIV
HIV Prevention
Precautions & Safety Measures for Heal…
-Sexual... a. Oral, Vaginal, Anal... -Blood Exposure... a. Occupatio…
-Reverse transcriptase assists to make viral DNA... -Viral DNA e…
-Use testing as routine health care... -Offer tests universally…
-Wash hands frequently and thoroughly before and after patien…
HIV Routes of Transmission
-Sexual... a. Oral, Vaginal, Anal... -Blood Exposure... a. Occupatio…
Pathophysiology of HIV
-Reverse transcriptase assists to make viral DNA... -Viral DNA e…
38 terms
HIV/AIDS
Describe the characteristics of Acquir…
Describe how AIDS is an epidemic
Describe the various causes of HIV
Describe the Origins of HIV
-Immune deficiency:... Opportunist infections... (TB, Candida, pn…
Zoonotic transmission (trans-species
Describe the characteristics of Acquir…
-Immune deficiency:... Opportunist infections... (TB, Candida, pn…
Describe how AIDS is an epidemic
HIV/AIDS
HIV
AIDS
Human Immunodeficiency Virus (HIV) att…
1 in (#) people with HIV don't know th…
Human Immunodeficiency Virus
Acquired Immunodeficiency Syndrome
Helper T cells
8 (and 60% of youth don't know they have HIV)
HIV
Human Immunodeficiency Virus
AIDS
Acquired Immunodeficiency Syndrome
48 terms
HIV/AIDS
AIDS-meaning
HIV-meaning
History of HIV-when discovered
Etiology
-Acquired Immunodeficiency Syndrome
-Human Immunodeficiency Virus
-first recognized in summer of 1981 (8 men in upstate new yor…
-Transmission
AIDS-meaning
-Acquired Immunodeficiency Syndrome
HIV-meaning
-Human Immunodeficiency Virus
228 terms
HIV/AIDS
Objectives slide #1
Objectives slide #2
What was the name of the activist grou…
HIV is what type of virus?
Act-Up (AIDS Coalition to Unleash Power)
Lentivirus (slowly replicating retrovirus)
Objectives slide #1
Objectives slide #2
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