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Study sets matching "immunity pathophysiology"

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Study sets matching "immunity pathophysiology"

96 terms
Pathophysiology-Immunity
Immunity
Structures of the IS
Examples of lymphoids
Self Ag
Protection from disease, specifically infectious disease
Lymphoid structures, immune cells/tissues, transportation/com…
Spleen, tonsils, thymus, bone marrow
Major Histocompatibility Complex (MHC)... Human Leukocyte Antige…
Immunity
Protection from disease, specifically infectious disease
Structures of the IS
Lymphoid structures, immune cells/tissues, transportation/com…
121 terms
Pathophysiology - Immunity
Mature B cells express which Ig on the…
Plasma cells secrete which antibodies…
What is the critical receptor between…
What is the B cell receptor for IgG?
IgM and IgD
IgA, IgE, and IgG
CD40
CD32
Mature B cells express which Ig on the…
IgM and IgD
Plasma cells secrete which antibodies…
IgA, IgE, and IgG
23 terms
Pathophysiology:Immunity
Immunity
Types of Natural Immunity:Non-specific
Types of Natural Immunity: SPECIFIC
Types of Acquired Immunity:Natural
*Specific defense mechanisms providing resistance to invading…
*Non-specific natural protective mechanisms that confers gene…
*Inherited specific protection against certain types of invad…
*A type of immunity due to a non-deliberate exposure in the c…
Immunity
*Specific defense mechanisms providing resistance to invading…
Types of Natural Immunity:Non-specific
*Non-specific natural protective mechanisms that confers gene…
109 terms
Pathophysiology: Immunity
Antigen
antibody
autoantibody
thymus
foreign substances, microbes or component of cell that stimul…
specific protein produced in humoral response to bind with an…
antibodies against self-antigen; attacks body's own tissues
gland located in the mediastinum, large in children, decreasi…
Antigen
foreign substances, microbes or component of cell that stimul…
antibody
specific protein produced in humoral response to bind with an…
175 terms
Immunity: Pathophysiology
How are the defenses of immunity divid…
First Line of Defense
Second Line of Defense
Third Line of Defense
The defenses of immunity are divided into:... 1. 1st line of def…
Innate resistance
Inflammation
Adaptive (acquired immunity)... -normal immune response
How are the defenses of immunity divid…
The defenses of immunity are divided into:... 1. 1st line of def…
First Line of Defense
Innate resistance
36 terms
PATHOPHYSIOLOGY : Immunity
Function of the immune system
Immunity
Immunocompetent
Antigen
To protect the body from invasion of foreign antigens, to ide…
Body's natural or induced response to infection and its relat…
Immune system that identifies antigens and effectively destro…
Foreign substances that trigger the immune response. ... Protein…
Function of the immune system
To protect the body from invasion of foreign antigens, to ide…
Immunity
Body's natural or induced response to infection and its relat…
36 terms
Pathophysiology-Immunity
Autoimmunity
Alloimmunity
IgE
IgD
disturbance in the immunologic tolerance of self-antigens
immune reaction to tissues of another individual
allergic response... causes release of histamines and other chem…
attached to B cells... Activates B cells
Autoimmunity
disturbance in the immunologic tolerance of self-antigens
Alloimmunity
immune reaction to tissues of another individual
234 terms
Pathophysiology Immunity
nonspecific response to antigen
performed by B and T cells; target spe…
5 forms of innate immunity
2 branches of Adaptive Immunity
Innate Immunity
Adaptive Immunity
1. Epithelial barriers... 2. Phagocytes... 3. Dendritic cells... 4. Pl…
Humoral and Cellular Immunity
nonspecific response to antigen
Innate Immunity
performed by B and T cells; target spe…
Adaptive Immunity
85 terms
Pathophysiology - Immunity
3 integrated parts of the immune system
Innate Immunity
Cellular components of Innate immunity
Innate - First Line
1. Inflammation... 2. Cell Mediated... 3. Antibody Mediated
-Requires no previous exposure... -Protein plasma system
Phagocytic cells
Physical, biochemical, and normal flora
3 integrated parts of the immune system
1. Inflammation... 2. Cell Mediated... 3. Antibody Mediated
Innate Immunity
-Requires no previous exposure... -Protein plasma system
35 terms
PATHOPHYSIOLOGY : Immunity
Function of the immune system
Immunity
Immunocompetent
Antigen
To protect the body from invasion of foreign antigens, to ide…
Body's natural or induced response to infection and its relat…
Immune system that identifies antigens and effectively destro…
Foreign substances that trigger the immune response. ... Protein…
Function of the immune system
To protect the body from invasion of foreign antigens, to ide…
Immunity
Body's natural or induced response to infection and its relat…
16 terms
Pathophysiology - Immunity
What is Natural Active Immunity?
What is Natural Passive Immunity?
What is Artificial Active Immunity?
What is Artificial Active Immunity?
..antibodies form in host after illness..
...antibodies passed from mother to child... ... ..temporary imm…
...vaccine, antibodies form...
...antibodies injected to provide temporary protection...
What is Natural Active Immunity?
..antibodies form in host after illness..
What is Natural Passive Immunity?
...antibodies passed from mother to child... ... ..temporary imm…
175 terms
Immunity: Pathophysiology
How are the defenses of immunity divid…
First Line of Defense
Second Line of Defense
Third Line of Defense
The defenses of immunity are divided into:... 1. 1st line of def…
Innate resistance
Inflammation
Adaptive (acquired immunity)... -normal immune response
How are the defenses of immunity divid…
The defenses of immunity are divided into:... 1. 1st line of def…
First Line of Defense
Innate resistance
175 terms
Immunity: Pathophysiology
How are the defenses of immunity divid…
First Line of Defense
Second Line of Defense
Third Line of Defense
The defenses of immunity are divided into:... 1. 1st line of def…
Innate resistance
Inflammation
Adaptive (acquired immunity)... -normal immune response
How are the defenses of immunity divid…
The defenses of immunity are divided into:... 1. 1st line of def…
First Line of Defense
Innate resistance
35 terms
PATHOPHYSIOLOGY : Immunity
Function of the immune system
Immunity
Immunocompetent
Antigen
To protect the body from invasion of foreign antigens, to ide…
Body's natural or induced response to infection and its relat…
Immune system that identifies antigens and effectively destro…
Foreign substances that trigger the immune response. ... Protein…
Function of the immune system
To protect the body from invasion of foreign antigens, to ide…
Immunity
Body's natural or induced response to infection and its relat…
175 terms
Immunity: Pathophysiology
How are the defenses of immunity divid…
First Line of Defense
Second Line of Defense
Third Line of Defense
The defenses of immunity are divided into:... 1. 1st line of def…
Innate resistance
Inflammation
Adaptive (acquired immunity)... -normal immune response
How are the defenses of immunity divid…
The defenses of immunity are divided into:... 1. 1st line of def…
First Line of Defense
Innate resistance
175 terms
Immunity: Pathophysiology
How are the defenses of immunity divid…
First Line of Defense
Second Line of Defense
Third Line of Defense
The defenses of immunity are divided into:... 1. 1st line of def…
Innate resistance
Inflammation
Adaptive (acquired immunity)... -normal immune response
How are the defenses of immunity divid…
The defenses of immunity are divided into:... 1. 1st line of def…
First Line of Defense
Innate resistance
52 terms
Pathophysiology Immunity
immunity
structures of the immune system
antigens
self
protection from disease, specifically infectious disease, col…
- lymphoid structures... - immune cells/tissues... - transportation…
proteins, polysaccharides, and/or glycoproteins on cell surface
major histocompatibility complex (human leukocyte antigen in…
immunity
protection from disease, specifically infectious disease, col…
structures of the immune system
- lymphoid structures... - immune cells/tissues... - transportation…
53 terms
Pathophysiology- Immunity
Abscess
Microflora
Pathogen
Antigen
Tender, easily pressed mass surrounded by dark red or pink an…
bacteria and microscopic algae and fungi, live in GI tract
infectious agent that causes disease or illness to host
Any substance that causes your immune system to produce antib…
Abscess
Tender, easily pressed mass surrounded by dark red or pink an…
Microflora
bacteria and microscopic algae and fungi, live in GI tract
96 terms
Pathophysiology-Immunity
Immunity
Structures of the IS
Examples of lymphoids
Self Ag
Protection from disease, specifically infectious disease
Lymphoid structures, immune cells/tissues, transportation/com…
Spleen, tonsils, thymus, bone marrow
Major Histocompatibility Complex (MHC)... Human Leukocyte Antige…
Immunity
Protection from disease, specifically infectious disease
Structures of the IS
Lymphoid structures, immune cells/tissues, transportation/com…
67 terms
Pathophysiology: immunity
Cytokines
Interleukins
Interleukin 1
Tumor necrosis factor (TNF alpha)
Any of several regulatory proteins, such as the interleukins…
Little proteins, Primarily made by macrophages and the lympho…
Promotes acute inflammatory response;... Stimulates coagulation…
Secreted primarily by macrophage in response to PAMPs (pathog…
Cytokines
Any of several regulatory proteins, such as the interleukins…
Interleukins
Little proteins, Primarily made by macrophages and the lympho…
48 terms
Pathophysiology- Immunity
List the three lines of defense:
Innate immunity:
Which line of defense is present at bi…
What is the purpose of inflammation?
1. Innate (natural) immunity... 2. Inflammatory response... 3. Adap…
includes both natural barriers (physical, mechanical, and bio…
innate immunity... first line
to protect the body from further injury or infection and to p…
List the three lines of defense:
1. Innate (natural) immunity... 2. Inflammatory response... 3. Adap…
Innate immunity:
includes both natural barriers (physical, mechanical, and bio…
64 terms
Immune Pathophysiology
Scalp
Layers of Scalp
Dangerous Area of Scalp
Meninges
Extends from supercilliary arches anteriorly to the external…
1.Skin... 2.Dense connective tissue... 3.Aponeurotic Layer... 4.Loose…
Dangerous area of scalp is the subaponeurotic space which con…
3 layers that cover the brain and spinal cord... -dura mater, a…
Scalp
Extends from supercilliary arches anteriorly to the external…
Layers of Scalp
1.Skin... 2.Dense connective tissue... 3.Aponeurotic Layer... 4.Loose…
19 terms
Immune Pathophysiology
Immune System
Innate immunity
Acquire immunity
Active acquired immunity
The function is to protect the human body from disease, neopl…
This type of nonspecific immunity is from natural or native a…
This is a adaptive or specific immunity that required B-cells…
An acquired immunity from vaccinations, natural contact, or i…
Immune System
The function is to protect the human body from disease, neopl…
Innate immunity
This type of nonspecific immunity is from natural or native a…
8 terms
Pathophysiology- Immune
Allergic Reaction- Etiology
Allergic Reaction- Risk Factors
Allergic Reaction- Chief Complaint
Allergic Reaction- PE
immune response causing an inflammatory reaction consisting o…
Known drug or food allergy
Rash, Swelling, Itching, or SOB
Edema, Facial Angioedema, Urticaria (Hives, Wheels)
Allergic Reaction- Etiology
immune response causing an inflammatory reaction consisting o…
Allergic Reaction- Risk Factors
Known drug or food allergy
43 terms
Immune Pathophysiology
Compartment of the immune system prese…
Compartment of the immune system that…
First line of defense?
How fast is the innate immune response…
innate immune system
adaptive immune system
Innate immune system
Innate is immediate or very fast, but the adaptive takes days…
Compartment of the immune system prese…
innate immune system
Compartment of the immune system that…
adaptive immune system
23 terms
Pathophysiology: Immunity & Abnormal Responses
Auto-immune disease
Goal of the Immune Response
Antigen
Antibodies
Immune system attacks its own host (body)
Recognize & remove perceived threats to the body (toxins, mic…
Any substance that stimulates the production of antibodies
Aka immunoglobulins... - Y shaped proteins on the surface of B-c…
Auto-immune disease
Immune system attacks its own host (body)
Goal of the Immune Response
Recognize & remove perceived threats to the body (toxins, mic…
62 terms
Pathophysiology: Adaptive Immunity & Infection
The immune response is more rapid afte…
Immune Defense System
__ ____: Has memory cells
The ____ progenator is part of the inn…
Adaptive immunity has memory
B lymphocytes
Myeloid
The immune response is more rapid afte…
Adaptive immunity has memory
Immune Defense System
21 terms
Pathophysiology: Immunity and Inflammation
Ig G
Ig A
Ig M
Ig D
Displays antiviral, antitoxin, and antibacterial properties,…
Predominant Ig in body secretions; protects mucous membranes
Forms natural antibodies; prominent in early immune responses…
Found on B lymphocytes, needed for maturation of B cells
Ig G
Displays antiviral, antitoxin, and antibacterial properties,…
Ig A
Predominant Ig in body secretions; protects mucous membranes
35 terms
Pathophysiology Ch. 7 Immunity
Immune System
Antigen
Macrophages
Bone marrow
Responsible for body's defense, non specific and specific
Unique to each individual, immune system will ignore self cel…
Initiate the immune response, develop from monocytes, they en…
Where are immune cells created?
Immune System
Responsible for body's defense, non specific and specific
Antigen
Unique to each individual, immune system will ignore self cel…
48 terms
Pathophysiology - Immunity Terms
Antibiotic
Antimicrobial
Antiviral
Autoantibodies
A substance derived from microorganisms that is used to treat…
An agent that kills or inhibits growth and reproduction of mi…
An agent that decreases the reproduction of viruses inside th…
Antibodies against self-antigen; attacks body's own tissues
Antibiotic
A substance derived from microorganisms that is used to treat…
Antimicrobial
An agent that kills or inhibits growth and reproduction of mi…
41 terms
Pathophysiology: Adaptive Immunity
clonal diversity
clonal selection
antigen
lymphocytes
occurs in specialized lymphoid organs (Thymus-T cells, and bo…
2nd phase of immune response; initiated by antigen; process w…
substances considered foreign or "non-self", on infectious ag…
extremely specific, each cell recognizes only one specific an…
clonal diversity
occurs in specialized lymphoid organs (Thymus-T cells, and bo…
clonal selection
2nd phase of immune response; initiated by antigen; process w…
33 terms
Pathophysiology chapt 7 - immunity
Antibiotic
Antimicrobial
Antivirus
Autoantibodies
...
...
...
...
Antibiotic
...
Antimicrobial
...
45 terms
Pathophysiology Chapter 7- Immunity
Immunity
Primary response
Secondary response
Types of immunity
-primary response... -secondary response
-first exposure to antigen ... -1 to 2 weeks for antibody titer…
-repeat exposure to the same antigen... -memory cells recognize…
-active natural immunity ... -active artificial immunity ... -passi…
Immunity
-primary response... -secondary response
Primary response
-first exposure to antigen ... -1 to 2 weeks for antibody titer…
32 terms
Pathophysiology Adaptive immunity
First Line of defense
Second Line of Defense
Third Line of Defense
Adaptive immune system
- Timing of defense is Constant... - Broadly specific Epithelial…
- Response to tissue damage or infection... - immediate response…
...
Specificity... Memory... - much slower
First Line of defense
- Timing of defense is Constant... - Broadly specific Epithelial…
Second Line of Defense
- Response to tissue damage or infection... - immediate response…
88 terms
Lecture 5 - Pathophysiology - Immunity/Immune System Disorders
immunity
specific, nonspecific
nonspecific
food allergy (peanuts), autoimmune rx…
the response by the body to "foreign" pathogens or substances…
Immunity may be ____, where the chemistry of foreign agent is…
With _____ the individual chemical type of the pathogen is no…
Examples of situation in which immunity may be destructive in…
immunity
the response by the body to "foreign" pathogens or substances…
specific, nonspecific
Immunity may be ____, where the chemistry of foreign agent is…
Pathophysiology Adaptive Immunity
Adaptive Immunity aka The Immune Respo…
Adaptive Immunity elements
Humoral and Cellular Adaptive Immunity
Active Immunity
Purpose: destruction of infectious microorganisms that are re…
antigens, lymphoctyes (T and B cells),
Both cellular (T and B cells) and humoral (antibodies) produc…
exposure to antigen (like through immunizations), activates B…
Adaptive Immunity aka The Immune Respo…
Purpose: destruction of infectious microorganisms that are re…
Adaptive Immunity elements
antigens, lymphoctyes (T and B cells),
33 terms
Pathophysiology Adaptive Immunity
adaptive immunity
antigens
Antigen presenting cells (APCs)
macrophages
recognizes and responds to large number of SPECIFIC antigens;…
foreign substances that stimulate an immune response (usually…
phagocytes--> macrophages, dendritic cells, lymphocytes
mature from monocytes, may be fixed or mobile
adaptive immunity
recognizes and responds to large number of SPECIFIC antigens;…
antigens
foreign substances that stimulate an immune response (usually…
44 terms
Pathophysiology Immunity & Abnormal Responses
Antigens (Self)
Antigens (Non-Self)
Types of immunity
Humoral immunity
Proteins label cells of the individual... Immune system ignores…
Immune system recognize specific non-self antigems as foreign…
Humoral & Cell-Mediated
Antibodies are produced yo protect body
Antigens (Self)
Proteins label cells of the individual... Immune system ignores…
Antigens (Non-Self)
Immune system recognize specific non-self antigems as foreign…
41 terms
Pathophysiology Exam 1 - Immunity
What is an infection?
What is an autoimmune response?
What is innate resistance?
Describe the innate protection of the…
an invasion in the body of some microorganisms
an immune reaction to your own body tissues if those tissues…
something you are born with, any anatomic or physiological fe…
In the mouth, pH is about 7, then in the stomach it goes to 1…
What is an infection?
an invasion in the body of some microorganisms
What is an autoimmune response?
an immune reaction to your own body tissues if those tissues…
41 terms
Pathophysiology: Adaptive Immunity
clonal diversity
clonal selection
antigen
lymphocytes
occurs in specialized lymphoid organs (Thymus-T cells, and bo…
2nd phase of immune response; initiated by antigen; process w…
substances considered foreign or "non-self", on infectious ag…
extremely specific, each cell recognizes only one specific an…
clonal diversity
occurs in specialized lymphoid organs (Thymus-T cells, and bo…
clonal selection
2nd phase of immune response; initiated by antigen; process w…
23 terms
Pathophysiology 5 - Innate Immunity - Objectives
Innate Immunity
Innate Immunity - First Line of Defens…
Innate Immunity - Second Line of Defen…
Innate Immunity - Third Line of Defens…
(natural or native immunity); includes natural barriers (phys…
Innate barriers are form of first line of defense at body's s…
if surface barriers are breached, the inflammatory response i…
adaptive immunity (acquired or specific immunity) is induced…
Innate Immunity
(natural or native immunity); includes natural barriers (phys…
Innate Immunity - First Line of Defens…
Innate barriers are form of first line of defense at body's s…
71 terms
Pathophysiology: Adaptive Immunity
two purposes of adaptive immunity
2 main characteristics of adaptive imm…
inducible
antigens
1. destroying infectious microorganisms resistant to inflamma…
-memory... -specific
must recognize pathogen as foreign or "non self"
molecules on infectious agents
two purposes of adaptive immunity
1. destroying infectious microorganisms resistant to inflamma…
2 main characteristics of adaptive imm…
-memory... -specific
70 terms
Pathophysiology: Adaptive Immunity
two purposes of adaptive immunity
inducible
antigens
products of adaptive immune system (2)
1. destroying infectious microorganisms resistant to inflamma…
must recognize pathogen as foreign or "non self"
molecules on infectious agents
1. immunoglobulins/antibodies... 2. lymphocytes (T/B cells)
two purposes of adaptive immunity
1. destroying infectious microorganisms resistant to inflamma…
inducible
must recognize pathogen as foreign or "non self"
73 terms
Pathophysiology - immunity (2.3)
Diagnostic test
Titer
Indirect coombs test
Elisa
test can assess levels of functional quality of serum immunog…
measures levels of serum immunoglobulins
detects Rh blood incompatibility
-detects for HIV antibodies... -used for a number of other disea…
Diagnostic test
test can assess levels of functional quality of serum immunog…
Titer
measures levels of serum immunoglobulins
64 terms
Pathophysiology Adaptive Immunity
Describe Adaptive Immunity
What are Antigens?
What are Immunogens?
What are Allergens?
-It's a later response... -Responds more slowly but more effecti…
-Bind with antibodies, receptors on T and B calles... -Not neces…
-Induce production of antibodies, T, and B cells... -Depends on…
Antigens that produce an allergic response
Describe Adaptive Immunity
-It's a later response... -Responds more slowly but more effecti…
What are Antigens?
-Bind with antibodies, receptors on T and B calles... -Not neces…
61 terms
Pathophysiology Week 4-Immunity
Myeloid Granulocytes
Neutrophils-Innate
Eosinophils/Basophils (mast cells)-Inn…
Monocytes/Macrophages
Neutrophils, eosinophils/basophils(mast cells), monocytes/mac…
-Most important cell in innate system.... -Short lived so many a…
Attack parasites which are too large for phagocytosis... Very im…
Innate AND adaptive;... Go to all the tissues and are long lived…
Myeloid Granulocytes
Neutrophils, eosinophils/basophils(mast cells), monocytes/mac…
Neutrophils-Innate
-Most important cell in innate system.... -Short lived so many a…
35 terms
Pathophysiology: Ch 7 Immunity
Immunology
Primary Functions of Immune System
Origination of cells in immune response
3 types of lymphocytes derived from bo…
study of immune system and responses
1. Differentiate between self and non-self... 2. Destroy non-self
bone marrow
1. B lymphocytes (B cells)... 2. T lymphocytes (T cells)... 3. Natu…
Immunology
study of immune system and responses
Primary Functions of Immune System
1. Differentiate between self and non-self... 2. Destroy non-self
52 terms
Pathophysiology- Immunity and Abnormal Responses
antigens
self cells
non-self
humoral immunity
proteins on the surface of a cell that help the immune system…
immune system ignores these
will be intruded because it is foreign;... develops an antibody…
antibodies are produced to protect the body
antigens
proteins on the surface of a cell that help the immune system…
self cells
immune system ignores these
10 terms
Pathophysiology - Adaptive Immunity
What is the third line of defense in t…
What is so unique about adaptive immun…
What are the end products of adaptive…
There is apart of adaptive immunity ca…
Adaptive Immunity
it has memory and it is specific
immunoglobins and lymphocytes (T cells, B cells)
antibodies
What is the third line of defense in t…
Adaptive Immunity
What is so unique about adaptive immun…
it has memory and it is specific
38 terms
Pathophysiology - Innate Immunity
What are the three human defense lines?
Describe the first line of defense.
Describe the second line of defense.
What are the goals of inflammation?
1. Innate immunity... 2. inflammation... 3. acquired immunity
skin, linings of gastrointestinal, genitourinary, and respira…
Inflammation, nonspecific, activated rapidly, vascularized, b…
initiate healing, prevent/limit infection and further damage
What are the three human defense lines?
1. Innate immunity... 2. inflammation... 3. acquired immunity
Describe the first line of defense.
skin, linings of gastrointestinal, genitourinary, and respira…
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