Study sets matching "immunity"

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Study sets matching "immunity"

86 terms
Immunity
Immunity or resistance
Immunogenicity
Antigen
Antibody
Ability of body to ward off damage/disease through our intern…
ability to provoke an immune response
Able to trigger a specific immune response against itself (ge…
-Used by immune system to identify and neutralize foreign obj…
Immunity or resistance
Ability of body to ward off damage/disease through our intern…
Immunogenicity
ability to provoke an immune response
65 terms
Immunity
Innate Immunity
Inflammatory response
Toll-like receptor
PAMP
First line of defense; non-specific; constitutive/rapidly ava…
Initiated by innate immunity (neutrophils, macrophages), recr…
receptors present on the extracellular face of dendritic cell…
pathogen-associated molecular patterns, which are recognized…
Innate Immunity
First line of defense; non-specific; constitutive/rapidly ava…
Inflammatory response
Initiated by innate immunity (neutrophils, macrophages), recr…
13 terms
Immunity
pathogen
macrophage
Antigen
t helper cells
An organism that causes disease
Found within the lymph nodes, they are phagocytes that destro…
A protein that, when introduced in the blood, triggers the pr…
Antigens bound to MHC II activate:
pathogen
An organism that causes disease
macrophage
Found within the lymph nodes, they are phagocytes that destro…
14 terms
Immunity
Phagocytes
Neutrophils
Macrophages
Lymphocytes
Two Types: Macrophages and Neutrophils. ... Produced throughout…
A type of phagocyte that produces about 60% of the white cell…
A type of phagocyte that is larger than a neutrophil. ... Origin…
Smaller than phagocytes. ... Large nucleus that fills most of th…
Phagocytes
Two Types: Macrophages and Neutrophils. ... Produced throughout…
Neutrophils
A type of phagocyte that produces about 60% of the white cell…
76 terms
Immunity
What are the six primary types of WBC's?
What are the two lineages of WBC's for…
What are the six types of phagocytic c…
What are neutrophils?
1. Polymorphonuclear neutrophils (62%)... 2. Polymorphonuclear e…
1. Myelocytic Lineage: gives rise to granulocytes and monocyt…
1. Neutrophils... 2. Monocytes and macrophages... 3. Eosinophils... 4.…
Neutrophils are the most abundant WBC and a type of phagocyte…
What are the six primary types of WBC's?
1. Polymorphonuclear neutrophils (62%)... 2. Polymorphonuclear e…
What are the two lineages of WBC's for…
1. Myelocytic Lineage: gives rise to granulocytes and monocyt…
13 terms
Immunity
infection
pathogen
immunity
disease
the invasion of the body by pathogenic microorganisms.
any disease-producing agent (especially a virus or bacterium…
the condition in which an organism can resist disease; may be…
an impairment of health or a condition of abnormal functioning.
infection
the invasion of the body by pathogenic microorganisms.
pathogen
any disease-producing agent (especially a virus or bacterium…
20 terms
Immunity
The two major types of phagocytic cell…
The diagram illustrates the stimulatio…
Histamine and leukotrienes are release…
Primary lymphatic organs include the
neutrophils and macrophages.
contact killing
basophils and mast cells.
red bone marrow and thymus.
The two major types of phagocytic cell…
neutrophils and macrophages.
The diagram illustrates the stimulatio…
contact killing
36 terms
Immunity
what cells are responsible for the imm…
where are they produced?
what two different types of wbc are th…
describe the first cell
White blood cell (leucocytes)
in the bone marrow
Lymphocytes and phagocytes
lymphocytes split into two different cells: B lymphocytes and…
what cells are responsible for the imm…
White blood cell (leucocytes)
where are they produced?
in the bone marrow
Immunity
Immunity
Immune System
Components of the Immune System
Types of Leukocytes
Human body constantly threatened by:... Foreign substances... Infec…
Complex network... Performs several functions:... Defends and prote…
Leukocytes (WBCs):... Primary cells... Derived from stem cells in b…
Granulocytes - 60-80% ... Myeloid stem cells of bone marrow... Prot…
Immunity
Human body constantly threatened by:... Foreign substances... Infec…
Immune System
Complex network... Performs several functions:... Defends and prote…
Immunity
1. What is the difference between inna…
2. What are TLR's- What are their func…
3. Identify some of the body's defense…
4. What are the functions of the lymph…
-Innate immunity refers to defenses that are present at birth…
The responses of the innate system are activated by protein r…
-(see question one diagram)
Lymph nodes are the sites of activation of T cells and 8 cell…
1. What is the difference between inna…
-Innate immunity refers to defenses that are present at birth…
2. What are TLR's- What are their func…
The responses of the innate system are activated by protein r…
Immunity
Immunity
Antigen
Antibody
Immune response
ability to the body to resist a specific pathogen
substance that triggers an immune response
protein that helps destroy pathogens
the body's specific defenses that attack a disease causing ag…
Immunity
ability to the body to resist a specific pathogen
Antigen
substance that triggers an immune response
Immunity
Resistance
Aquired immunity
Active immunity
Passive immunity
Natural or innate
Protection against specific microbes or foreign substance
Develops after exposure to microorganisms or foreign substance
Acquired when antibodies are transferred from one person to a…
Resistance
Natural or innate
Aquired immunity
Protection against specific microbes or foreign substance
Immunity
Pathogen
Virus
Bacteria
HIV
Disease-producing agents such as bacteria, protozoans, fungi,…
A small infectious agent that can replicate only inside the l…
Microscopic single-celled organisms that thrive in diverse en…
Caused by a virus and destroys helper T cells. Leads to AIDS.
Pathogen
Disease-producing agents such as bacteria, protozoans, fungi,…
Virus
A small infectious agent that can replicate only inside the l…
22 terms
Immunity
Innate (Natural) immunity (non-specifi…
Adaptive (Acquired) Immunity
Mast cells
Neutrophil
First line of defense. Included the skin, mucous membranes, a…
Third line of defense. Includes specialized lymphocytes: B ce…
Function: allergy, inflammation, antigen presentation, immuno…
Function: Cytotoxicity, phenotypic plasticity, vascular remod…
Innate (Natural) immunity (non-specifi…
First line of defense. Included the skin, mucous membranes, a…
Adaptive (Acquired) Immunity
Third line of defense. Includes specialized lymphocytes: B ce…
70 terms
Immunity
Innate and Adaptive Immunity
Natural, Non-Specific and Adaptive Imm…
Acquired, Specific and Adaptive Immunity
Physical Barrier, Genetically controll…
(2) Types of Immunity
Other names of Innate Immunity
Other names of Adaptive Immunity
Innate Imuunity Barriers (3)
Innate and Adaptive Immunity
(2) Types of Immunity
Natural, Non-Specific and Adaptive Imm…
Other names of Innate Immunity
14 terms
immunity
immunity
cytokine
complement
opsonization
ability to recognize foreign materials and destroy or neutral…
- serve as inflammatory mediators or messengers... - way cells c…
serum proteins that coat pathogens so that they can be more e…
coating of pathogens with complement... - breaks down the pathog…
immunity
ability to recognize foreign materials and destroy or neutral…
cytokine
- serve as inflammatory mediators or messengers... - way cells c…
47 terms
immunity
inflammation
infection, trauma, injury, immune reac…
vasodilation and vascular permeability
rubor, tumor, calor, dolor
-a complex nonspecific response to tissue injury intended to…
causes of inflammation include...
mediators of inflammation increase:
hallmarks of inflammation include...
inflammation
-a complex nonspecific response to tissue injury intended to…
infection, trauma, injury, immune reac…
causes of inflammation include...
immunity
immune response
3 protective activities
recognition
Communication
Most powerful defense mechanism in the body. It reacts in res…
recognition, communication and elimination.
body distinguishes between local and foreign cells by display…
cells behave a certain way which results in a specific immune…
immune response
Most powerful defense mechanism in the body. It reacts in res…
3 protective activities
recognition, communication and elimination.
Immunity
Asthma
Rheumatic fever
Juvenile-onset diabetes
Myasthenia gravis
Smooth muscle contractions reduce size of air passageways in…
Antibodies and killer T cells kill and scar cells of the hear…
An autoimmune reaction attacks the insulin-producing cells of…
Antibodies attack the nerve receptors of the muscles
Asthma
Smooth muscle contractions reduce size of air passageways in…
Rheumatic fever
Antibodies and killer T cells kill and scar cells of the hear…
Immunity
Immunity
Antibody
antigen
Immune response
Ability of the body to resist a specific pathogen.
Protein that helps destroy pathogens.
Substance that triggers an immune response.
The bod's specific defenses that attack a disease-causing age…
Immunity
Ability of the body to resist a specific pathogen.
Antibody
Protein that helps destroy pathogens.
Immunity
Immunity
Complement
Innate immunity
Adaptive immunity
An organisms capactity to resist and combat infection
Is a set of proteins that circulate in inactivate form thorou…
Pattern receptors and the responses they initiate are apart of
Tailors immune defenses to a vast array of specific pathogens…
Immunity
An organisms capactity to resist and combat infection
Complement
Is a set of proteins that circulate in inactivate form thorou…
12 terms
Immunity
Helper T cells
Killer T cells
Memory T cells
Suppressor T cells
stimulate T+B cell proliferation
engage in cell-cell combat, leads to cell lysis
remembers antigen
inhibits T+B cell proliferation
Helper T cells
stimulate T+B cell proliferation
Killer T cells
engage in cell-cell combat, leads to cell lysis
14 terms
Immunity
Lysozyme
Lactoferrin
Cathelicidins, dedensins
Complement
Breaks down peptidoglycan, hood against gram positive, tears…
Binds free iron in body fluids, binds to LPS and leads to lyr…
Antimicrobial peptides, small proteins that have antimicrobia…
>20 serum proteins, opsonization inflammation and physics of…
Lysozyme
Breaks down peptidoglycan, hood against gram positive, tears…
Lactoferrin
Binds free iron in body fluids, binds to LPS and leads to lyr…
12 terms
Immunity
Plasma Cells
Humoral Response
Cell Mediated Response
Passive Immunity
Produce antibodies
B cells are the primary cells, production of antibodies
T cells are the primary cells
Using antibodies created by another person
Plasma Cells
Produce antibodies
Humoral Response
B cells are the primary cells, production of antibodies
54 terms
Immunity
*Response of the immune system is medi…
*Two categories of immune response
*Innate Immunity
*Acquired Immunity
cytokines (protein messengers) and antibodies
innate and acquired
non-specific, rapid, may destroy everything (not specific pat…
specific, slow, adaptive, imparts memory, distinguishes betwe…
*Response of the immune system is medi…
cytokines (protein messengers) and antibodies
*Two categories of immune response
innate and acquired
Immunity
Pathogens
Innate immunity
Acquired immunity
First line of defense
Bacteria, viruses or other microorganism that can cause disease
Non specific, responds to all pathogens in the same way. Is v…
Develops slowly and your body must know or learn about the pa…
Skin and mucus membranes.... digestive track is technically o…
Pathogens
Bacteria, viruses or other microorganism that can cause disease
Innate immunity
Non specific, responds to all pathogens in the same way. Is v…
9 terms
Immunity
Toll-like receptors
PAMPs
PAMPs
Specialized tissues where resident mac…
molecules found on the surface and inside innate immune cells
pathogen-associated molecular patterns
foreign molecules ... Help the innate immunity recognize pathoge…
microglial cells (brain)... kupffer cells (liver)... alveolar cells…
Toll-like receptors
molecules found on the surface and inside innate immune cells
PAMPs
pathogen-associated molecular patterns
Immunity
2 elements of immunity
Elements of innate immunity
Physical barriers of innate immune sys…
Lysozyme
Innate defenses and adaptive immunity
physical barriers, chemical barriers, and cellular barriers
skin (dermis with connective tissues, and epidermis with epit…
antimicrobial substance degrades peptidoglycan, found in tear…
2 elements of immunity
Innate defenses and adaptive immunity
Elements of innate immunity
physical barriers, chemical barriers, and cellular barriers
22 terms
Immunity
Altered immunity
Suppressed immune response
Exaggerated immune response
Innate immunity
Conditions in which immune responses are either suppressed or…
Referred to as immunocompromised or immunodeficiency
Referred to as hypersensitive
Immunity present at birth; a it provides nonspecific response…
Altered immunity
Conditions in which immune responses are either suppressed or…
Suppressed immune response
Referred to as immunocompromised or immunodeficiency
Immunity
neutrophils
eosinophils and basophils
monocytes/macrophages
mast cells
phagocytes and release enzymes
secrete chemical mediators
attack pathogens by engulfing and killing microorganism by en…
regulate inflammatory response
neutrophils
phagocytes and release enzymes
eosinophils and basophils
secrete chemical mediators
98 terms
Immunity
Resistance:
Susceptibility:
Lack of resistance:
Specific Resistance:
Ability to fight off diseases... Ex. Healthy Skin
Lack of resistance.
Ex. Broken skin or HIV (T4 Cells)
Antibodies that protects.
Resistance:
Ability to fight off diseases... Ex. Healthy Skin
Susceptibility:
Lack of resistance.
Immunity
Immunity
Non-specific immunity
Mast Cells
Histamines
The ability to neutralize internal threats, like microorganis…
Involves inflammation, mucus production, histamine release, s…
Release histamines
Cause capillaries to swell and release nitric oxide which att…
Immunity
The ability to neutralize internal threats, like microorganis…
Non-specific immunity
Involves inflammation, mucus production, histamine release, s…
Immunity
pathogens
nonspecific (innate) immunity
specific (acquired) immunity
microbe
disease-causing agents
inborn, same defenses regardless of pathogen type (1st line:…
part inborn, part developed; specific attack against specific…
micro-organism causing disease or fermentation (yeast)
pathogens
disease-causing agents
nonspecific (innate) immunity
inborn, same defenses regardless of pathogen type (1st line:…
13 terms
Immunity
specific category of immunity
Antigen-presenting cells
Characteristics of Primary immunity
Characteristics of secondary immunity
(adaptive) ... Learned from exposure... A function of lymphocytes a…
antigen presenting cells present foreign antigen on their sur…
IgM... Short duration ... Low level of Ab production ... 5-10 days
IgG... Long duration ... High level of Ab production ... <2 years
specific category of immunity
(adaptive) ... Learned from exposure... A function of lymphocytes a…
Antigen-presenting cells
antigen presenting cells present foreign antigen on their sur…
45 terms
Immunity
Lymphatic vessels
Lymphatic organs
Lymph nodes
Spleen
Collect fluid loss from blood vessels when it returns to the…
All house phagocytes and lymphocytes
Filters lymph, ... activates immune system
Activates immune system, cleans blood
Lymphatic vessels
Collect fluid loss from blood vessels when it returns to the…
Lymphatic organs
All house phagocytes and lymphocytes
IMMUNITY
Immunity
PAMPS
Antigen
Complement Proteins
The capacity to resist & combat infection
Pathogen-Associated Molecular Patterns
Molecule/particle recognized by the body as non-self
Destroy invading cells/mark them for phagocytosis
Immunity
The capacity to resist & combat infection
PAMPS
Pathogen-Associated Molecular Patterns
Immunity
Functions of the Immune System
Innate Immune System
Host Pathogen relationship
First line Defense
-keep microorganisms out... -remove microorganisms... -fight microo…
-present since birth... -first and second line of defense... -preve…
pathogens infect hosts, hosts develop immunity, pathogens dev…
-skin... -mucous membranes... -secretions... -normal flora
Functions of the Immune System
-keep microorganisms out... -remove microorganisms... -fight microo…
Innate Immune System
-present since birth... -first and second line of defense... -preve…
Immunity
Non-specific Immunity
Specific Immunity
Cell mediated immunity
Humoral immunity
General Protection
Protection against specific pathogens
Uses T-lymphocytes
Uses B-lymphocytes
Non-specific Immunity
General Protection
Specific Immunity
Protection against specific pathogens
19 terms
Immunity
Neutrophils
Eosinophils
Basophils
Monocytes
Phagocytosis
parasite destruction and allergic reactions
histamine and heparin release, allergic reactions
transform into macrophages, phagocytosis
Neutrophils
Phagocytosis
Eosinophils
parasite destruction and allergic reactions
8 terms
Immunity
Innate immunity
Acquired/adaptive immunity
Examples of External/Innate barriers
Examples of Body defences
Nonspecific defence mechanisms. For example, external barrier…
Highly specialised, systematic cells and processes that preve…
Skin, saliva, tears, mucus, stomach acid and 'good' gut bacte…
White blood cells. For example, B and T Lymphocytes. Also ant…
Innate immunity
Nonspecific defence mechanisms. For example, external barrier…
Acquired/adaptive immunity
Highly specialised, systematic cells and processes that preve…
46 terms
Immunity
bone marrow thymus
spleen
innate
neutrophil
B cells mature in the _________ ___________ while the T cells…
Patients that have this organ removed are at a higher risk fo…
This type of immunity is characterized by a non-specific resp…
make up 60-70% of WBCs in circulation; first-responders to in…
bone marrow thymus
B cells mature in the _________ ___________ while the T cells…
spleen
Patients that have this organ removed are at a higher risk fo…
80 terms
Immunity
Innate immunity
Acquired immunity
Acquired active immunity
Active acquired: naturally acquired
present at birth
after birth
antibodies developed after exposure to antigen
through environmental exposure to pathogens i.e. measles, chi…
Innate immunity
present at birth
Acquired immunity
after birth
Immunity
First line of defence- Non specific im…
Second Line of defence- non specific i…
Third Line of defence- Non specific im…
Active Natural
Mechanical barriers(skin) Chemical barriers( acidic environme…
Phagocytosis( phagocytic cells ingest and destroy all microbe…
Natural killer cells(NK cells are a group of lymphocytes that…
(get the disease, produce the immunity) Results from natural…
First line of defence- Non specific im…
Mechanical barriers(skin) Chemical barriers( acidic environme…
Second Line of defence- non specific i…
Phagocytosis( phagocytic cells ingest and destroy all microbe…
47 terms
Immunity
Immune System
Anti-tumor effects
pro-tumor effects
innate immunity
Protects the host from infectious agents and promotes repair…
Recognition and destruction of tumor cells and virally infect…
Long-term inflammation can promote carcinogenesis.
Early, non-specific immune response that is mediated by immun…
Immune System
Protects the host from infectious agents and promotes repair…
Anti-tumor effects
Recognition and destruction of tumor cells and virally infect…
61 terms
Immunity
Innate Defences
Surface Barriers
Internal Defences
Phagocytes
Fast. non-specific
Mechanical, external. Skin and mucous membranes
Cells and chemicals. Phagocytes, NK cells, Inflammation, Anti…
Neutrophill and eosinophil
Innate Defences
Fast. non-specific
Surface Barriers
Mechanical, external. Skin and mucous membranes
immunity
pathogen
antigen
vector
host cell
causes diseases
•proteins on pathogen's surface ... •causes an immune response
carries pathogens from one host to another
infected cell
pathogen
causes diseases
antigen
•proteins on pathogen's surface ... •causes an immune response
6 terms
immunity
passive natural
passive artifical
active natural
active artifical
antibodies pass through breast milk/placenta
short term by injection of antibodies
exposed to a live pathogen/develops disease
induced by vaccine
passive natural
antibodies pass through breast milk/placenta
passive artifical
short term by injection of antibodies
Immunity
Innate (Nonspecific) body defenses
adaptive (specific) body defenses
Humoral (antibody- mediated) response
Humoral response peak production
first line of defense i.e. skin, phagocytes, natural killer c…
second line of defense, specific activation i.e. immune respo…
initiated when antigen encounters b cell
in about 10 days
Innate (Nonspecific) body defenses
first line of defense i.e. skin, phagocytes, natural killer c…
adaptive (specific) body defenses
second line of defense, specific activation i.e. immune respo…
Immunity
hypersensitivity
Type 1 (allergic disorder)
Type 2 (bad blood)
Type 3 (complex)
an innappropriate response to an antigen
type of hypersensitivity ... lgE mediated... Releasing cell media…
Type of hypersensitvity ... reactions are mediated by lgG or lg…
type of hypersensitivity ... results from failure of immune sys…
hypersensitivity
an innappropriate response to an antigen
Type 1 (allergic disorder)
type of hypersensitivity ... lgE mediated... Releasing cell media…
IMMUNITY
Pathogens, prevent
Self, foreign
Bacteria, viruses, and fungi
Innate immunity
Immunity includes the ability to destroy __________________ a…
Antigens are chemical markers, and there are two general type…
Name three different kinds of foreign antigens
Does not involve antibodies...... does involve the process of…
Pathogens, prevent
Immunity includes the ability to destroy __________________ a…
Self, foreign
Antigens are chemical markers, and there are two general type…
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