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Study sets matching "infection pathophysiology inflammation"

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Study sets matching "infection pathophysiology inflammation"

54 terms
pathophysiology - inflammation and infection
vascular phase
Hyperemia
Mast Cells
Exudates
brief vasoconstriction followed by vasodilation leading to in…
increased blood supply
secrete histamine, bradykinin which increase permeability and…
serous = skin blisters. Fibrinous - adhesions. Purulent - boi…
vascular phase
brief vasoconstriction followed by vasodilation leading to in…
Hyperemia
increased blood supply
27 terms
Pathophysiology - Infection/inflammation
Microorganisms/Human Relationship
Stages of Infection
Factors for Infection
Classes of Infectious Microorganisms
- Mutal relationship - microbiome... - Normal flora... - Relationsh…
- Portal of entry - direct contact, inhalation or ingestion... (…
- Mechanism of action:... Toxins, Adhesion, Evasion. and Invasio…
Prions - Not alive not dead. ... Some transmissible spongiform e…
Microorganisms/Human Relationship
- Mutal relationship - microbiome... - Normal flora... - Relationsh…
Stages of Infection
- Portal of entry - direct contact, inhalation or ingestion... (…
120 terms
Pathophysiology Inflammation, Infection and Fever
Non-specific Resistance to Disease: 1s…
Non-specific Resistance to Disease: 2n…
Structures of the immune system
Lymph nodes
Mechanical Factors:... -Skin... -Mucous membranes... -Hair... -Cilia... -Lac…
Internal defenses:... -Antimicrobial proteins... --Interferons(glyc…
Lymph nodes... Thymus... Spleen... Tonsils... Red bone marrow
Distribute along lymphatic vessels... Filter lymph fluid(simila…
Non-specific Resistance to Disease: 1s…
Mechanical Factors:... -Skin... -Mucous membranes... -Hair... -Cilia... -Lac…
Non-specific Resistance to Disease: 2n…
Internal defenses:... -Antimicrobial proteins... --Interferons(glyc…
38 terms
Pathophysiology Inflammation, Infection, Fever
Primary Lymphatic Organs
Secondary Lymphatic Organs & Tissues
Resistance
Susceptibility
-Provide environment for stem cells ... to divide & mature... Ex: R…
-Sites where most immune responses occur... Ex:Lymph nodes, Sple…
-Ability to ward off disease
-Vulnerability or lack of resistance to disease
Primary Lymphatic Organs
-Provide environment for stem cells ... to divide & mature... Ex: R…
Secondary Lymphatic Organs & Tissues
-Sites where most immune responses occur... Ex:Lymph nodes, Sple…
40 terms
Pathophysiology: Infection, Inflammation, & Immunity
Inflammatory response
Plasma Protein Systems
Complement system
Coagulation system
NONSPECIFIC response that depends on cellular & cheical com…
Complement system... Coagulation system... Kinin system... - all conta…
- Activates or collaborates with all inflammatory response…
- fibrinous meshwork to prevent spread of infection, stops…
Inflammatory response
NONSPECIFIC response that depends on cellular & cheical com…
Plasma Protein Systems
Complement system... Coagulation system... Kinin system... - all conta…
41 terms
pathophysiology immunity, inflammation, infection
first line of defense
second line of defense
third line of defense
Inflammation
innate immunity
inflammation
acquired immunity
Biochemical and cellular process, nonspecific universal respo…
first line of defense
innate immunity
second line of defense
inflammation
73 terms
Pathophysiology Infection, Inflammation, Immunity
Antigen
Antibody
Environmental Factors that affect prev…
Role of Immunizations
The foreign substance submitted to body.
Antibody is circulating protein that will fight off the antig…
-Climatic conditions/air quality... -Overcrowded living conditio…
-Most cost effective method of altering host's susceptibility…
Antigen
The foreign substance submitted to body.
Antibody
Antibody is circulating protein that will fight off the antig…
93 terms
Pathophysiology - Immunity, infection, inflammation
what is a type 1 hypersensitivity?
what are the symptoms of a type 1 hype…
what is happening in a type 1 hypersen…
what is anaphylaxis?
extreme response of immune system to an antigen
sniffling, runny nose, hay fever, resp. distress, edema, card…
-excessive production of IgE antibodies after exposure to an…
vascular shock, widespread edema and difficulty breathing
what is a type 1 hypersensitivity?
extreme response of immune system to an antigen
what are the symptoms of a type 1 hype…
sniffling, runny nose, hay fever, resp. distress, edema, card…
43 terms
Pathophysiology Chapter 4 Inflammation and Infection
Abscess
Adhesion
Antibody
Antigen
A localized collection of puss.
As normal fibrous tissue develops in the operative organ, par…
Immune bodies,or proteins that the body produces to react to…
A toxin or other foreign substance that induces an immune res…
Abscess
A localized collection of puss.
Adhesion
As normal fibrous tissue develops in the operative organ, par…
Pathophysiology Chapter 4: Inflammation and Infection
What are the three lines of defense th…
which defense mechanisms are nonspecif…
consists of the skin and mucous membra…
when antibodies are produces that are…
physical or surface barriers, inflammation, and the immune re…
Physical or surface barriers and inflammation
physical or surface barriers
immune response
What are the three lines of defense th…
physical or surface barriers, inflammation, and the immune re…
which defense mechanisms are nonspecif…
Physical or surface barriers and inflammation
44 terms
Pathophysiology - Chapter 4 - Inflammation and Infection
bacteria
antigens
antibodies
trauma
Microscopic, one-celled organisms
Protein or saccharide markers in every cell that identify the…
Immunoglobulins that develop in response to an antigen; also…
Injury
bacteria
Microscopic, one-celled organisms
antigens
Protein or saccharide markers in every cell that identify the…
126 terms
Pathophysiology Thermoregulation/Infection/Inflammation/Immunity
Thermoregulation
Normothermia
Hypothermia
Hyperthermia
The process of maintaining core body temperature at a near co…
temperature is within normal range (taking into account age)
temperature is lower than normal value
temperature is above the normal value
Thermoregulation
The process of maintaining core body temperature at a near co…
Normothermia
temperature is within normal range (taking into account age)
9 terms
Pathophysiology cell death, infection & inflammation
Hypertrophy
Atrophy
Metaplasia
Dysplasia
Increased size. ... (Muscle: smooth, cardiac, skeletal)
Reduce size
Change/replace cell type
Abnormal nucleus, size,& shape
Hypertrophy
Increased size. ... (Muscle: smooth, cardiac, skeletal)
Atrophy
Reduce size
126 terms
Pathophysiology Thermoregulation/Infection/Inflammation/Immunity
Thermoregulation
Normothermia
Hypothermia
Hyperthermia
The process of maintaining core body temperature at a near co…
temperature is within normal range (taking into account age)
temperature is lower than normal value
temperature is above the normal value
Thermoregulation
The process of maintaining core body temperature at a near co…
Normothermia
temperature is within normal range (taking into account age)
52 terms
Klassen 1 - pathophysiology of infection and inflammation
LOs
Infections - how are they caused?
Difference between epidemic, endemic,…
Difference between symptoms and signs
•Explain the epidemiology and natural history of infections a…
INfestation and propagation of bacteria, viruses, fungi, or p…
Epidemic - local... Endemic - normal level of disease... Pandemic -…
- Symptoms are determined by the patient: Pain, nausea, fatig…
LOs
•Explain the epidemiology and natural history of infections a…
Infections - how are they caused?
INfestation and propagation of bacteria, viruses, fungi, or p…
65 terms
Pathophysiology Week 5- Respiratory Inflammation and Infection
upper respiratory infection
lobes of the lungs
respiratory patterns
aspiration pneumonia
one of the most frequent reasons for patients to seek care, w…
there are two lobes of the lung tissue on the left; there are…
right middle lobe- common area for aspiration pneumonia, ausc…
upper respiratory infection
one of the most frequent reasons for patients to seek care, w…
lobes of the lungs
there are two lobes of the lung tissue on the left; there are…
43 terms
Chapter 4 Vocabulary: Inflammation and Infection Pathophysiology
abscess
adhesion
antibody
antigen
a localized collection of pus
parts of tissue that cling to the surface of adjoining organs…
immunoglobulins that develop in response to an antigen; also…
a cell marker that induces a state of sensitivity after comin…
abscess
a localized collection of pus
adhesion
parts of tissue that cling to the surface of adjoining organs…
156 terms
Pathophysiology Exam I: Inflammation, Infection, & Fever
Host Defense Systems
Inflammatory response
Immune response
1st line of defense (non-specific)
Physical & chemical barriers to infection (skin, mucous membr…
After tissue injury or infection, immediate & general protect…
Specific, antigen-antibody response, identifies self from non…
Mechanical factors (cilia, lacrimal apparatus, mucus) & chemi…
Host Defense Systems
Physical & chemical barriers to infection (skin, mucous membr…
Inflammatory response
After tissue injury or infection, immediate & general protect…
85 terms
Pathophysiology Exam 1 - Inflammation, Infection and Fever
Inflammatory Response
Immune response (antigen- antibody)
1st Line of Defense:... Mechanical
1st Line of Defense:... Chemical
- non-specific... - occurs after tissue injury or infection... - im…
- specific... - recognizes and eliminates altered host cells... - d…
- skin (physical barrier)... - mucous membranes... - hairs... - cilia…
- pH of skin... - unsaturated fatty acids: gives the phospholipi…
Inflammatory Response
- non-specific... - occurs after tissue injury or infection... - im…
Immune response (antigen- antibody)
- specific... - recognizes and eliminates altered host cells... - d…
24 terms
Pathophysiology: Physiologic Alterations: Inflammation, Infection and Immunity
Anaphylaxis
Antigen
Autoimmunity
Eosinophils
A severe, potentially life-threatening allergic reaction.... Rap…
a toxin or other foreign substance that induces an immune res…
is the system of immune responses of an organism against its…
a white blood cell containing granules that are readily stain…
Anaphylaxis
A severe, potentially life-threatening allergic reaction.... Rap…
Antigen
a toxin or other foreign substance that induces an immune res…
125 terms
Pathophysiology Final- New Concepts(Inflammation/Infection/Elimination)
Definition of Inflammation
Inflammatory Response Characteristics
Function of Inflammatory Response
4 Outcomes of Inflammation
=An immunologic defense against tissue injury, infection, or…
-Tissues must be vascularized... -Activated within seconds of da…
-Return cells to normal functioning after injury... -Fibrous rep…
***First Outcome: Healing (Most Desired)... -Period of acute inf…
Definition of Inflammation
=An immunologic defense against tissue injury, infection, or…
Inflammatory Response Characteristics
-Tissues must be vascularized... -Activated within seconds of da…
45 terms
Pathophysiology - Inflammation
gangrene
pathogens
microbe
capillary
local death and decay of soft tissues of the body as a result…
microorganisms that cause disease
microscopic organism
thin-walled blood vessel that connects small arteries with sm…
gangrene
local death and decay of soft tissues of the body as a result…
pathogens
microorganisms that cause disease
79 terms
Pathophysiology:Physiologic alterations:Inflammation, infections and immunity
Anaphylaxis
Antibody
Antigen
Autoimmunity
SEVERE ALLERGIC REACTION
a substance produced by the body that destroys or inactivates…
A protein or carbohydrate that, when introduced in the blood…
Adaptive immunity specific for an antigenic component of the…
Anaphylaxis
SEVERE ALLERGIC REACTION
Antibody
a substance produced by the body that destroys or inactivates…
69 terms
Inflammation Pathophysiology
the immune system
inflammation
catabasis
inflammation
distinguishes self from "non-self
1 swelling... 2 redness... 3 warmth... 4 pain... 5 loss of function... media…
decline, tapering off
integral part of immune response... occurs rapidly in response t…
the immune system
distinguishes self from "non-self
inflammation
1 swelling... 2 redness... 3 warmth... 4 pain... 5 loss of function... media…
213 terms
Pathophysiology Quiz 2 (electrolytes, infection, inflammation, stress and pain)
Homeostasis
Stressor
Severe or prolonged stress can cause d…
GAS - General Adaptation Syndrome
body's compensation to minor changes in the environment
factor that creates significant change in body function
Increased wear and tear on tissues... Exhaustion of resources... Ex…
Alarm stage:... Mobilization of defenses... Hypothalamus, sympathet…
Homeostasis
body's compensation to minor changes in the environment
Stressor
factor that creates significant change in body function
42 terms
physiology and Pathophysiology- Immunity, Inflammation, & Infection- exam 1 Dr Arbour
ABCD of hypersensitivity
Type I hypersensitivity
Type II hypersensitivity
Type III hypersensitivity
A- Allergic, Anaphylaxis & atopy... B- antiBody mediated ... C- imm…
Allergies, anaphylaxis, and atopy... -after initial exposure, sp…
AnitBody mediated... -IgM or IgG don't recognize self - start at…
Immune Complex mediated... -antigen+antibody bind together in ci…
ABCD of hypersensitivity
A- Allergic, Anaphylaxis & atopy... B- antiBody mediated ... C- imm…
Type I hypersensitivity
Allergies, anaphylaxis, and atopy... -after initial exposure, sp…
102 terms
Pathophysiology - Inflammation
Five indicators of inflammation
calor
rubor
tumor
heat, redness, tenderness, swelling, pain
heat
redness
swelling
Five indicators of inflammation
heat, redness, tenderness, swelling, pain
calor
heat
30 terms
Pathophysiology-Inflammation
The inflammatory response
Inflammation
Causes of Inflammation
Inflammation
1-Generally Beneficial(anaphylaxis)... 2-Can cause injury... 3-Eith…
a tissue reaction to injury that characteristically involves…
Microorganism, trauma, heat, cold, radiation, chemical or hyp…
Inflammation is non-specific and lacks memory... Immune response…
The inflammatory response
1-Generally Beneficial(anaphylaxis)... 2-Can cause injury... 3-Eith…
Inflammation
a tissue reaction to injury that characteristically involves…
38 terms
Pathophysiology 10 Inflammation
A biochemical and cellular process tha…
a break in the continuity of a tissue…
infection from microorganisms... physical…
rubor - redness... tumor - swelling... calor…
Give the definition of inflammation
Give the definition of wound
List four causes of inflammation
List the five clinical manifestations of inflammation.
A biochemical and cellular process tha…
Give the definition of inflammation
a break in the continuity of a tissue…
Give the definition of wound
29 terms
Pathophysiology: Inflammation
#1 Inflammation
4 Purposes of Inflammation
6 Characteristics of the Inflammatory…
Overview of the Components of the Infl…
...
1. Destroy infectious and injurious organisms... 2. Wall off th…
1. Occurs in vascular tissues (not avascular)... 2. Immediate R…
1. Cells: White blood cells (WBCs), endothelial cells, and pl…
#1 Inflammation
...
4 Purposes of Inflammation
1. Destroy infectious and injurious organisms... 2. Wall off th…
58 terms
Pathophysiology inflammation
Inflammation
Inflammation
Inflammation
Inflammation
Prevents spread of damaging agents to nearby tissues
Disposes of cell debris and pathogens
Prepares the area for repair process
Is not the same thing as infection. Microorganisms are always…
Inflammation
Prevents spread of damaging agents to nearby tissues
Inflammation
Disposes of cell debris and pathogens
38 terms
Pathophysiology: Inflammation
First line of defense
Second line of defense
Third line of defense
Inflammation
physical and mechanical barriers, biochemical barriers
inflammation
adaptive immunity
the sum of the body's efforts to destroy the invading organis…
First line of defense
physical and mechanical barriers, biochemical barriers
Second line of defense
inflammation
10 terms
Pathophysiology Inflammation
Purpose Inflammation
3 general causes of inflammation
what tissue agent causes the initial t…
T or F: Inflammation response is diffe…
destroy dilute infectious agent... start repair and regeneration…
Acquired , congenital and genetic
STROMA ... (CT, vascular tissues, arterioles, capillaries, aerol…
FALSE ... part of non specific innate immune system so its the s…
Purpose Inflammation
destroy dilute infectious agent... start repair and regeneration…
3 general causes of inflammation
Acquired , congenital and genetic
17 terms
Pathophysiology - Inflammation
Innate immunity
Adaptive immunity
first line of defense in innate immunity
second line of defense in innate immun…
composed of a first and a second line of defense
third line of defense, is induced in a slower and more specif…
physical, mechanical, and biochemical barriers to invasion
inflammatory response, phagocytosis
Innate immunity
composed of a first and a second line of defense
Adaptive immunity
third line of defense, is induced in a slower and more specif…
45 terms
Pathophysiology Inflammation
Inflammation occurs in what area?
Characteristics of Capillaries
Percentage that goes to lymphatic syst…
Pre-Cappilary sphincter
Vascularized tissue ... Occurs in the endothelium junction and w…
Provide exchange of O2, nutrients, and waste between blood ve…
10% lymph ... 90% vein
Controls the perfusion to the capillaries
Inflammation occurs in what area?
Vascularized tissue ... Occurs in the endothelium junction and w…
Characteristics of Capillaries
Provide exchange of O2, nutrients, and waste between blood ve…
73 terms
Inflammation Pathophysiology
What are our primary defenses?
Inflammation occurs in response to
Inflammation is designed to deliver wh…
Purpose of inflammation of is to (3)
Skin and mucous membranes
exogenous or endogenous cell injury
Leukocytes and plasma proteins
- Neutralize invasion... - Limit speed... - Remove debris or prepar…
What are our primary defenses?
Skin and mucous membranes
Inflammation occurs in response to
exogenous or endogenous cell injury
67 terms
Inflammation and Infection
Initial response to damage in epitheli…
What is the first inflammatory cell on…
What do the platelets active for the n…
Blood vessel response to injury?
Bleeding and coagulation
Platelets
cytokines/chemoattractants
Damaged blood vessels initially constrict, but later dilate a…
Initial response to damage in epitheli…
Bleeding and coagulation
What is the first inflammatory cell on…
Platelets
47 terms
Pathophysiology: Inflammation
Inflammation can be ________: also cal…
Define natural barriers.
What are the mechanical and chemical b…
What is inflammation?
specific and non-specific
Our first line of defence includes the epithelial layer of th…
Mechanical: ridding the body of pathogens includes sloughing,…
Our second line of defence. It is the protective response des…
Inflammation can be ________: also cal…
specific and non-specific
Define natural barriers.
Our first line of defence includes the epithelial layer of th…
92 terms
PATHOPHYSIOLOGY-INFLAMMATION
Human defense mechanisms work to?
What is the first line of defense
Biochemical barriers are where on the…
The skin does what as a biochemical ba…
protect from injury and infection
physical and mechanical barriers-epithelial cells tightly ass…
the skin.
produces lactic acid in sebaceous glands. And perspires, it c…
Human defense mechanisms work to?
protect from injury and infection
What is the first line of defense
physical and mechanical barriers-epithelial cells tightly ass…
54 terms
Pathophysiology inflammation
Blood
Plasma
Lymphocytic
Myelocytic
Plasma + cells (RBC, WBC, platelets)
Water (90%), Protein (9%), Ca++, glucose, hormones, etc (1%)
lymphocytes - T & B cells
granulocytes, monocytes, RBC, platelets
Blood
Plasma + cells (RBC, WBC, platelets)
Plasma
Water (90%), Protein (9%), Ca++, glucose, hormones, etc (1%)
31 terms
Inflammation - Pathophysiology
Types of Healing (3)
Resolution
Regeneration
Replacement
1. Resolution... 2. Regeneration... 3. Replacement
(Healing) all damaged cells return to normal... - little tissue…
(Healing) damaged cells replaced with functional cells... - capa…
(Healing) No function... - NO mitosis
Types of Healing (3)
1. Resolution... 2. Regeneration... 3. Replacement
Resolution
(Healing) all damaged cells return to normal... - little tissue…
21 terms
Pathophysiology Inflammation
Important Opsonins
Oxygen dependent Killing
Oxygen Independent Killing
Serous Inflammation
antibodies IgG (most important), C3b, collecting
strongest, myeloperoxidase halide system, HOCl result
less effective, can damage host tissue, mediated by lysozyme,…
transudate, protein poor fluid (effusion), peritoneum, pleura…
Important Opsonins
antibodies IgG (most important), C3b, collecting
Oxygen dependent Killing
strongest, myeloperoxidase halide system, HOCl result
58 terms
Pathophysiology inflammation
Inflammation
Inflammation
Inflammation
Inflammation
Prevents spread of damaging agents to nearby tissues
Disposes of cell debris and pathogens
Prepares the area for repair process
Is not the same thing as infection. Microorganisms are always…
Inflammation
Prevents spread of damaging agents to nearby tissues
Inflammation
Disposes of cell debris and pathogens
55 terms
Pathophysiology - Inflammation
inflammatory response
The Immune Response
The Inflammatory Response
1. acute inflammation... 2. chronic infla…
the body's response to cellular injury
-develops slowly... -response is specific (targets specific anti…
-develops swiftly... -response is nonspecific ... -temporary (lasts…
Phases of inflammation:
inflammatory response
the body's response to cellular injury
The Immune Response
-develops slowly... -response is specific (targets specific anti…
17 terms
Pathophysiology Inflammation
Inflammation response
2 phase tissue reaction to injury
Vascular Phase
Cellular Phase
Usually beneficial response to invasion by microorganisms or…
1. Vascular & Cellular work to destroy substances foreign to…
Involves chemical mediators from either plasma or cells
Happens after vascular phase
Inflammation response
Usually beneficial response to invasion by microorganisms or…
2 phase tissue reaction to injury
1. Vascular & Cellular work to destroy substances foreign to…
48 terms
Pathophysiology: Inflammation
First line of defense
Second line of defense
Natural Immunity (innate response)
Third line of defense
Skin
Inflammation
First and Second line of defense
Adaptive immunity
First line of defense
Skin
Second line of defense
Inflammation
26 terms
Inflammation / Infection
Atrophy
Hypertrophy
Dysplasia
Hyperplasia
Reduced tissue mass, decrease in size of cells
Enlarged tissue mass, increase in size of individual cells
Vary in size and shape, large nuclei - may indicate precancer…
Increase in number of cells, can occur with hypertrophy
Atrophy
Reduced tissue mass, decrease in size of cells
Hypertrophy
Enlarged tissue mass, increase in size of individual cells
22 terms
Pathophysiology: Inflammation
chronic inflammation
purposes of inflammation
consequence of inflammation
rubor
heals by scar tissue only
sends fluid to dilute microorganisms, limits further damage,…
leads to damage of un-injured cells
redness
chronic inflammation
heals by scar tissue only
purposes of inflammation
sends fluid to dilute microorganisms, limits further damage,…
15 terms
Inflammation/Infection
4500-11000
50-70
4-10
16-45
normal leukocytes present in adults
% Neutrophils of the TWBC
% Monocytes of TWBC
% lymphocytes of TWBC
4500-11000
normal leukocytes present in adults
50-70
% Neutrophils of the TWBC
78 terms
Pathophysiology- Inflammation
What are causes of inflammation?
Aids in the basis of treatment
Inflammation
Examples of the inflammatory process
Infection response, injury response
Inflammation
Basis of research in many disease states
1.) Coronary Disease... 2.) MI... 3.) Chronic Brochitis... 4.) Allergi…
What are causes of inflammation?
Infection response, injury response
Aids in the basis of treatment
Inflammation
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