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Study sets matching "liver pathology"

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Study sets matching "liver pathology"

34 terms
Liver Pathology
LR QI STAGNATION TURNING INTO HEAT Ton…
LR QI STAGNATION TURNING INTO HEAT: TR…
LR QI STAGNATION... Tongue, Pulse
LR QI STAGNATION:SYMPTOMS
Tongue: red on sides... Pulse: wiry, esp on L and slightly rapid,
TX= Smooth the LR, move qi, lightly clear heat. Same as LR qi…
T=Normal or slightly red, P=wiry,
sxs=abdominal distention, depression, moodiness, lump in thro…
LR QI STAGNATION TURNING INTO HEAT Ton…
Tongue: red on sides... Pulse: wiry, esp on L and slightly rapid,
LR QI STAGNATION TURNING INTO HEAT: TR…
TX= Smooth the LR, move qi, lightly clear heat. Same as LR qi…
87 terms
Liver Pathology
Acinus organization
Liver sinusoids
Kupffer cells
Perisinusoidal stellate cells of Ito
1. Periportal: closest to portal vein and hepatic artery (tra…
-lined by fenestrated and discontinuous endothelial cells
-macrophages... -attached to the luminal face of the endothelia…
-contain fat... -found in the space of Disse
Acinus organization
1. Periportal: closest to portal vein and hepatic artery (tra…
Liver sinusoids
-lined by fenestrated and discontinuous endothelial cells
19 terms
Liver Pathology Ultrasound Images
Ultrasound appearance of
Ultrasound appearance of
Ultrasound appearance of
Ultrasound Appearance of
Acute Hepatitis
chronic hepatitis
Budd-Chiari Syndrome- IVC Thrombus
Cystic Metastasis
Ultrasound appearance of
Acute Hepatitis
Ultrasound appearance of
chronic hepatitis
38 terms
Liver Pathology
metabolic functions of liver
hepatic enzymes
biliary enzymes
hepatic triad
carbohydrate metabolism... synthesis of fatty acids, cholesterol…
aspartate aminotransferase (AST/SGOT)... alanine aminotransferas…
alkaline phosphotase (ALP)... gamma-glutamyl transferase (GGT)
area of 2 hepatic arteries and 1 portal vein
metabolic functions of liver
carbohydrate metabolism... synthesis of fatty acids, cholesterol…
hepatic enzymes
aspartate aminotransferase (AST/SGOT)... alanine aminotransferas…
55 terms
Liver Pathology
Hereditary Hemochromatosis def
Hereditary Hemochromatosis clinical pr…
hereditary hemochromatosis pathogenesis
hereditary hemochromatosis treatment
autosomal recessive ... excessive iron absorption and accumulati…
1. cirrhosis ... 2. DM... 3. skin pigmentation (bronze)
iron is directly toxic to tissues ... causes lipid peroxidation…
phlebotomy
Hereditary Hemochromatosis def
autosomal recessive ... excessive iron absorption and accumulati…
Hereditary Hemochromatosis clinical pr…
1. cirrhosis ... 2. DM... 3. skin pigmentation (bronze)
18 terms
Liver Pathology
Diffuse Hepatocellular Disease
Steatosis / Fatty Infiltration
Which liver pathology is considered to…
Glycogen Storage Disease
Dysfunction of Hepatocytes
Accumulation of triglycerides in hepatocytes
Fatty Liver
Autosomal recessive diease
Diffuse Hepatocellular Disease
Dysfunction of Hepatocytes
Steatosis / Fatty Infiltration
Accumulation of triglycerides in hepatocytes
48 terms
Liver pathology
3 categories of morhophological change…
what changes can be seen in fatty live…
Fibrosis in Steatohepatitis
Etiology of alcoholic liver disease
- steatosis ... -hepatitis (alcoholic)... -fibrosis
-hepatocellular ballooning (cells undergo swelling an necrosi…
-first in centrilobular region (space of Disse): central vein…
short term ->80g/day -> reversible changes... chronic ->40-80g/…
3 categories of morhophological change…
- steatosis ... -hepatitis (alcoholic)... -fibrosis
what changes can be seen in fatty live…
-hepatocellular ballooning (cells undergo swelling an necrosi…
47 terms
Liver Pathology
Steatosis
Focal or spotty necrosis
Centrizonal (near central veins)
Midzonal (between portal and central a…
fat accumulations within hepatocyte cytoplasm ... leads to ball…
viral infection
heart disease or med toxicity
yellow fever
Steatosis
fat accumulations within hepatocyte cytoplasm ... leads to ball…
Focal or spotty necrosis
viral infection
102 terms
Pathology: Liver
What vitamins are stored by the liver?
How does the liver detoxify blood?
How does the liver act as a physical f…
How does the liver act as a biochemica…
A, D, E, K... B12... Iron... Stores large amount of blood
Detoxifies the blood of substances from the gut via the porta…
Bacteria and particulates are trapped and broken down in the…
Phase 1: cytochrome P450... -Enzymes in hepatic cells break down…
What vitamins are stored by the liver?
A, D, E, K... B12... Iron... Stores large amount of blood
How does the liver detoxify blood?
Detoxifies the blood of substances from the gut via the porta…
38 terms
Liver pathology
Porta hepatis consists of
Lobules are...
Acini are...
5 general responses to hepatic injury
Portal vein. Heaptic artery. Bile duct.
Anatomical form
Functional. 3 zones
Inflammation. Degeneration and intracellular accumulation (fa…
Porta hepatis consists of
Portal vein. Heaptic artery. Bile duct.
Lobules are...
Anatomical form
44 terms
Liver Pathology
degeneration of hepatocytes and intrac…
toxin insult
fat-steatosis, bilirubin-cholestasis
sudden destruction of liver or endpoin…
What are the 5 general responses of the liver to damage?
What type of damage commonly results in necrosis or apoptosis?
What are examples of intracellular accumulation that can occu…
What is hepatic failure?
degeneration of hepatocytes and intrac…
What are the 5 general responses of the liver to damage?
toxin insult
What type of damage commonly results in necrosis or apoptosis?
19 terms
Liver Pathology
Reidel's Lobe
HEPATOMEGALY
Steatosis
DIFFUSE FATTY INFILTRATION
A tongue-like extension of right lobe -extends below inferi…
Swelling of the liver beyond its normal size.... Upper limit of…
Fatty Infiltration of the Liver... is an acquired, reversible me…
Mild to severe... Increased echogenicity... Poor penetration... Loss o…
Reidel's Lobe
A tongue-like extension of right lobe -extends below inferi…
HEPATOMEGALY
Swelling of the liver beyond its normal size.... Upper limit of…
23 terms
Liver Pathology
Fatty Infiltration
Focal Fatty Infiltration
Focal Fatty Sparing
Acute Hepatitis
increase lipid accumulation in hepatocytes... results from ... -maj…
Focal region of increased echogenicity within normal liver... MC…
focal regions of normal parenchyma in a fatty liver, MC adjac…
Inflammatory and infectious disease of the liver due to virus…
Fatty Infiltration
increase lipid accumulation in hepatocytes... results from ... -maj…
Focal Fatty Infiltration
Focal region of increased echogenicity within normal liver... MC…
68 terms
Liver Pathology
5 general responses of hepatic injury
cause of hereditary hyperbilirubinemias
functional enzyme bilirubin is complet…
complication of Crigler-Najjar Type 1
1. Degeneration --> swelling; intracellular accumulation of i…
may be a genetic deficiency of the bilirubin enzyme UGT 1A1
Crigler-Najjar Syndrome Type 1... (can't conjugate bilirubin)
death within 18 months due to kernicterus
5 general responses of hepatic injury
1. Degeneration --> swelling; intracellular accumulation of i…
cause of hereditary hyperbilirubinemias
may be a genetic deficiency of the bilirubin enzyme UGT 1A1
39 terms
Liver Pathology
Hydropic degeneration
Fatty change
Amyloid infiltration
Focal necrosis
Cause:... -Anaemia/hypoxia... -Starvation... -Recently anesthetised... -D…
Cause:... -Abnormal accumulation of fat within hepatocytes... -Keto…
-Amyloid deposited between the sinusoid reticulin meshwork an…
Microscopic foci of necrosis... Causes:... -Bacterial infections
Hydropic degeneration
Cause:... -Anaemia/hypoxia... -Starvation... -Recently anesthetised... -D…
Fatty change
Cause:... -Abnormal accumulation of fat within hepatocytes... -Keto…
23 terms
liver pathology
fatty liver diffuse
focal fatty liver
hepatitis
cirrhosis
diffusely echogenic. difficult to penetrate
area of increased echogenicity. can appear like a solid, hype…
nonobstructive jaundice. increased LFT. starry sky. hepatospl…
echogenic, small RT lobe. enlarged caudate and LT lobe. nodul…
fatty liver diffuse
diffusely echogenic. difficult to penetrate
focal fatty liver
area of increased echogenicity. can appear like a solid, hype…
38 terms
Liver Pathology
Chronic (autoimmune) Hepatitis
IgG
Cirrhosis
Stellate Cell
Characterized by infiltration of plasma cells at the portal t…
Elevated in chronic hepatitis
End-stage liver damage most commonly seen due to HBV, HCV, al…
Secretes TGF-B, mediating fibrosis.
Chronic (autoimmune) Hepatitis
Characterized by infiltration of plasma cells at the portal t…
IgG
Elevated in chronic hepatitis
16 terms
Liver Pathology
Four causes of UNCONGUGATED Bilirubine…
Gilbert syndrome
Crigler-Najjar syndrome Type II
Dubin-Johnson syndrome
Hemolytic Anemias... Physiologic in Newborns... Gilberts... Crigler-Na…
Unconjugated hyperbilirubinemia due to bilirubin UDP-glucuron…
Unconjugated hyperbilirubinemia due to bilirubin UDP-glucuron…
Decreased bilirubin excretion due to a defect in the canalicu…
Four causes of UNCONGUGATED Bilirubine…
Hemolytic Anemias... Physiologic in Newborns... Gilberts... Crigler-Na…
Gilbert syndrome
Unconjugated hyperbilirubinemia due to bilirubin UDP-glucuron…
28 terms
Liver pathology
simple hepatic cyst
CT simple cyst appearance
Possible side effects of large cysts
Adult polycystic kidney disease
asymptomatic, normal LFTs, may have palpable mass, smooth wal…
density similar to water, darker shade of gray
may interfere with normal liver function, elevated LFTs
autosomal dominant, often produces symptoms of renal failure…
simple hepatic cyst
asymptomatic, normal LFTs, may have palpable mass, smooth wal…
CT simple cyst appearance
density similar to water, darker shade of gray
44 terms
liver pathology
causes of chronic passive congestion
infarcatin is rare but may result from…
peliosis hepatis--what is it, what can…
nutmeg apperance
right sided heart failure, tricuspid valvular dz, cardiac tam…
hepatic artery
dilatation of blood-filled sinusoids; ... advanced stage can cau…
chronic venous congestion
causes of chronic passive congestion
right sided heart failure, tricuspid valvular dz, cardiac tam…
infarcatin is rare but may result from…
hepatic artery
14 terms
Liver Pathology
nuclear details fade... cells shrink... more…
loss of all architecture... nulcei and cy…
ceroid laden macrophages... kupffer cell…
non-necrotizing granulomas in the live…
apoptosis
coagulative necrosis
liver damage (portal and lobar inflammation)
sarcoidosis
nuclear details fade... cells shrink... more…
apoptosis
loss of all architecture... nulcei and cy…
coagulative necrosis
9 terms
Liver pathology
Hepatitis B
Acute hepatitis
Ultrasound findings of acute hepatits
Clinical or biochemicql evidence of he…
Greatest risk to healthcare workers
Liver cell injury which may lead to cell nevrosis
PV walls more prominent
Chronic hepatitis
Hepatitis B
Greatest risk to healthcare workers
Acute hepatitis
Liver cell injury which may lead to cell nevrosis
117 terms
Liver Pathology
The blood volume within the liver is n…
In health and at rest, the liver recei…
Portal Vein
Hepatic Artery
About 10% of total blood volume
About 30% of cardiac output
About 70% of blood supply to liver... Brings in oxygen poor but…
About 30% hepatic blood supply... Supplies most of the oxygen re…
The blood volume within the liver is n…
About 10% of total blood volume
In health and at rest, the liver recei…
About 30% of cardiac output
52 terms
Liver pathology
Diffuse disease
Fatty Infiltration
fatty infiltration
Fatty Sparing
Affects the hepatocytes and interferes with liver function.
Acquired, reversible disorder of metabolism, resulting in an…
US Appear: hyperechoic liver echotexture and an increase in a…
normal liver tissue 'spared' of infiltration (will look dark)
Diffuse disease
Affects the hepatocytes and interferes with liver function.
Fatty Infiltration
Acquired, reversible disorder of metabolism, resulting in an…
41 terms
Liver Pathology
Diffuse hepatocellular disease
Fatty infiltration
Sonographic appearance of fatty infilt…
Symptoms of liver diffuse pathology
affects the hepatocytes and interferes with liver function
increased lipid accumulation in the hepatocytes resulting fro…
increased echogenicity and attenuation, impaired visualizatio…
increased lfts
Diffuse hepatocellular disease
affects the hepatocytes and interferes with liver function
Fatty infiltration
increased lipid accumulation in the hepatocytes resulting fro…
47 terms
Liver Pathology
lobule
acinus
zone 1
zone 3
multiple portal tracts surrounding a central vein
portal tract & adjacent central vein, enzyme expression, oxyg…
zone around the portal tract
zone around the central vein
lobule
multiple portal tracts surrounding a central vein
acinus
portal tract & adjacent central vein, enzyme expression, oxyg…
30 terms
Liver pathology
Fungal abscess
Candidiasis
Clinical and lab data of candidiasis
Sono appearance of candidiasis
Complications seen in patients with HIV and other immune comp…
Fungus normally found in humans ... Normals immune system keeps…
RUQ pain... Fever... Hepatomegaly
Varies:... "Wheel within a wheel" or "bullseye"... Hypoechoic lesio…
Fungal abscess
Complications seen in patients with HIV and other immune comp…
Candidiasis
Fungus normally found in humans ... Normals immune system keeps…
74 terms
Liver Pathology
True Cyst
Simple Cyst
Sono Appearance of a Simple Cyst
Polycystic Disease
A fluid filled space having an epithelial lining
Have an unknown etiology... Often asymptomatic ... Occur in females
Anechoic... Thin, well defined wall... Posterior acoustic enhanceme…
Inherited as an autosomal dominant pattern... Can be a few to 50…
True Cyst
A fluid filled space having an epithelial lining
Simple Cyst
Have an unknown etiology... Often asymptomatic ... Occur in females
380 terms
Liver Pathology
Which proteins are produced by the liv…
What is stored in the liver?
Name 5 basic physiological roles of th…
Describe the basic role of the liver i…
Albumin, clotting factors, enzymes, non-essential amino acids
Fat soluble vitamins (ADEK, B12), many of the coagulation fac…
production of bile, metabolism and energy production, storage…
Synthesis of lipids and plasma lipoproteins occurs in the liv…
Which proteins are produced by the liv…
Albumin, clotting factors, enzymes, non-essential amino acids
What is stored in the liver?
Fat soluble vitamins (ADEK, B12), many of the coagulation fac…
6 terms
Liver Pathology
Glycogen storage disease
Polycystic liver disease
Hepatic abscesses
Routes for bacteria to gain access to…
autosomal recessive; genetic; type one most common
cysts are small, less than 2-3 mm; may enlarge and cause bili…
occur most often as a complication of biliary tract disease,…
1. biliary tree, portal vein or hepatic artery; 2. a direct e…
Glycogen storage disease
autosomal recessive; genetic; type one most common
Polycystic liver disease
cysts are small, less than 2-3 mm; may enlarge and cause bili…
Liver Pathology
sonographic findings for AIDS
pneumocystic jiroveci sonographic find…
sclerosing and AIDS cholangitis sonogr…
lymphoma and Kaposi's sarcoma sonograp…
pneumocystic (carinii) jiroveci (MC opportunistic infection w…
diffuse, non-shadowing, hyperechoic foci in liver
thick biliary ducts
intrahepatic mass, diffuse infiltration
sonographic findings for AIDS
pneumocystic (carinii) jiroveci (MC opportunistic infection w…
pneumocystic jiroveci sonographic find…
diffuse, non-shadowing, hyperechoic foci in liver
15 terms
Pathology- Liver
75%
1. primary pathway for elimination of…
1. hepatic failure... 2. cirrhosis... 3. por…
hepatic failure
Removal of up to ________ of the liver is still compatible wi…
2 major functions of hepatic bile formation
4 major clinical syndromes associated with liver disease
can occur by slow cell-by-cell erosion, repetitive waves of d…
75%
Removal of up to ________ of the liver is still compatible wi…
1. primary pathway for elimination of…
2 major functions of hepatic bile formation
liver pathology
Metastatic liver disease
Fatty infiltrate
Cirrhosis
Primary liver cancer
colon, breast, lung... Spread via PV, hepatic artery, lymphatic…
problem metabolizing fats, can be entire liver or just some p…
destroys normal liver tissue, parenchyma deformed by fibrous…
men over 40, usually have cirrhosis... rare... increased AFP
Metastatic liver disease
colon, breast, lung... Spread via PV, hepatic artery, lymphatic…
Fatty infiltrate
problem metabolizing fats, can be entire liver or just some p…
62 terms
Liver Pathology
Patterns of hepatic injury
Hepatic failure
Clinical features of hepatic failure i…
Kupffer cells are part of the ________…
Limited repertoire of responses to injury - 5 general respons…
Sudden & massive destruction or endpoint of chronic damage... Ap…
Jaundice (failure to metabolise bilirubin normally)... Hypoalbum…
Monocyte/macrophage
Patterns of hepatic injury
Limited repertoire of responses to injury - 5 general respons…
Hepatic failure
Sudden & massive destruction or endpoint of chronic damage... Ap…
22 terms
Liver Pathology
Explain the structure of the liver
What makes up the Portal Triad?
Describe the normal histology of the l…
Steatosis
The liver is made up of hepatocytes and is mainly supplied by…
Portal Vein, Hepatic Artery and Bile Duct
The liver consists of hepatocytes. At the interface of each h…
accumulation of triglycerides in hepatocytes
Explain the structure of the liver
The liver is made up of hepatocytes and is mainly supplied by…
What makes up the Portal Triad?
Portal Vein, Hepatic Artery and Bile Duct
32 terms
Liver pathology
cirrhosis
portal hypertention
enzymes related to liver damage
functional liver markers
diffuse broad bands of bridging fibrosis in liver... - via stell…
incr pressure in portal venous system... etiologies: cirrhosis,…
AST and ALT... - in most liver dz ALT>AST... - in alcoholic AST>ALT…
bilirubin - incr in various liver dz... - eg. biliary obstructio…
cirrhosis
diffuse broad bands of bridging fibrosis in liver... - via stell…
portal hypertention
incr pressure in portal venous system... etiologies: cirrhosis,…
15 terms
Liver Pathology
3 parts of the structural framework
carry out most of the livers functions
phagocytosis of immune complexes
mobile w/i the sinusoids
capsule, trabeculae, reticular network
hepatocytes
Kupffer cells
Kupffer cells
3 parts of the structural framework
capsule, trabeculae, reticular network
carry out most of the livers functions
hepatocytes
59 terms
Liver Pathology
A benign neoplasm containing cystic st…
Cystadenomas are rare and occur most o…
An inherited disorder of female preval…
With polycystic disease, where may mul…
Cystadenoma
Middle-aged women
Polycystic disease
Kidneys, Pancreas, Spleen, Liver
A benign neoplasm containing cystic st…
Cystadenoma
Cystadenomas are rare and occur most o…
Middle-aged women
110 terms
Liver Pathology
Liver Function Tests (Lft's)
Two types of disease processes
Hepatocellular
Obstructive
Group of various laboratory (blood) tests established to prov…
Hepatocellular and obstructive
Affects hepatocytes, treated medically
Flow of bile is prevented, treated surgically
Liver Function Tests (Lft's)
Group of various laboratory (blood) tests established to prov…
Two types of disease processes
Hepatocellular and obstructive
203 terms
Liver pathology
portal v., hepatic a., and bile duct e…
how does blood flow in a classic liver…
space of Disse
bile canaliculi
porta hepatis
portal triad to central v.
space btw. hepatocytes and sinusoids... contains lymph/interstit…
btw. adjacent hepatocytes, normally protected by tight juncti…
portal v., hepatic a., and bile duct e…
porta hepatis
how does blood flow in a classic liver…
portal triad to central v.
14 terms
Liver Pathology
Hepatocellular adenoma
Focal nodular hyperplasia
Hepatic angioma
HCC
Women BCP... Can rupture and bleed into peritoneum... Smooth appear…
Not a true neoplasm... Due to focal vascular abnormality and rem…
Most common tumor... Small and asymptomatic. Can cause abd pain…
Bad prognosis... Risk factors: Cirrhosis, Hep, hemochromatosis,…
Hepatocellular adenoma
Women BCP... Can rupture and bleed into peritoneum... Smooth appear…
Focal nodular hyperplasia
Not a true neoplasm... Due to focal vascular abnormality and rem…
13 terms
Liver Pathology
simple hepatic cyst
polycystic liver disease
pyogenic abscess
hepatic candidiasis
solitary, non parasitic cyst. enechoic, thin walls, well defi…
autosomal dominant, multiple small cysts throughout liver. Hx…
puss forming abscess, when bacteria gain access to liver
fungus invades bloodstream, wheel within a wheel, fever
simple hepatic cyst
solitary, non parasitic cyst. enechoic, thin walls, well defi…
polycystic liver disease
autosomal dominant, multiple small cysts throughout liver. Hx…
57 terms
Liver - Pathology
Most common benign
Most common malignant
Most common malignancy in infancy
Most common primary metastatic disease
Hemangioma
Hepatocellular carcinoma (hepatoma)
Hepatoblastoma
Colon
Most common benign
Hemangioma
Most common malignant
Hepatocellular carcinoma (hepatoma)
49 terms
Liver Pathology
Hepatic encephalopathy
Hepatorenal syndrome
Cirrhosis
Portal hypertension
-Affects brain... -Rigidity, hyperreflexia, asterixis... -Hyperammo…
-Renal failure assoc. w/ severe liver disease... -Decrease urine…
-Collagen deposition in all portions of hepatic lobule... -Ito c…
-Increased resistance to peripheral bloodflow
Hepatic encephalopathy
-Affects brain... -Rigidity, hyperreflexia, asterixis... -Hyperammo…
Hepatorenal syndrome
-Renal failure assoc. w/ severe liver disease... -Decrease urine…
76 terms
Liver Pathology
Define and describe the functions of n…
Describe the sequence of vessels invol…
Liver Injury: Degeneration and IC accu…
Liver Injury: Necrosis and Apoptosis
Portal tract = Portal triad = hepatic artery, portal vein (la…
Dual Blood Supply - both enter at hilum... Portal vein and Hepat…
IC Accumulations - Micro and macrovesicular steatosis - fat i…
Centrilobular Necrosis - around central veins - ischemia, hea…
Define and describe the functions of n…
Portal tract = Portal triad = hepatic artery, portal vein (la…
Describe the sequence of vessels invol…
Dual Blood Supply - both enter at hilum... Portal vein and Hepat…
57 terms
Liver Pathology
regeneration priming
progression to mitosis
non-parenchymal cells divide
hepatocyte integrity
G0 -> G1 of parenchymal cells, IL-6 and TNFa
enhance mitotic function, HGF/SF, EGF, TGFa
sinusoidal epithelial, Kupfur, stellate, biliary epithelial
AST, ALT, LDH
regeneration priming
G0 -> G1 of parenchymal cells, IL-6 and TNFa
progression to mitosis
enhance mitotic function, HGF/SF, EGF, TGFa
44 terms
Liver Pathology
Periportal hepatocytes
Periacinar hepatocytes (centrolobular…
Kupffer cells
Pit cells
Zone 1 hepatocytes that are closest to the nutrient/oxygen ri…
Zone 3 hepatocytes closest to the central vein and furthest f…
Fixed-tissue macrophages within sinusoidal lumens... -Removes de…
Large, granular lymphocytes with NK cell activity in sinusoid…
Periportal hepatocytes
Zone 1 hepatocytes that are closest to the nutrient/oxygen ri…
Periacinar hepatocytes (centrolobular…
Zone 3 hepatocytes closest to the central vein and furthest f…
63 terms
Liver Pathology
in the center of each of the liver lob…
what is in the periphery of the liver…
zone 1 is around the portal triad and…
zone 3 is around the .... and has the…
central vein
portal area
hepatic artery... -have greater o2 supply
central ring... -o2 flows from zone 1 to 3
in the center of each of the liver lob…
central vein
what is in the periphery of the liver…
portal area
81 terms
Liver Pathology
Primary Diseases of the Liver
Patterns of Hepatic Injury
Most common intrahepatic cause of bloo…
Impaired blood flow through the liver…
Viral Hepatitis... Alcoholic Liver Disease ... Nonalcoholic Fatty L…
Hepatocyte degeneration and intracellular accumulations... Hepat…
Cirrhosis
Impaired flow --> Passive congestion --> Centrilobular Necrosis
Primary Diseases of the Liver
Viral Hepatitis... Alcoholic Liver Disease ... Nonalcoholic Fatty L…
Patterns of Hepatic Injury
Hepatocyte degeneration and intracellular accumulations... Hepat…
Liver pathology
Fatty infiltration
Fatty infiltration CLINICAL
Fatty infiltration SONO
Hepatitis
acquired, reversible condition of metabolism, resulting in an…
Asymptomatic... Minimal hepatomegaly... Minimal elevated LFTs
Normal or hepatomagaly... Diffused or focal Increased liver echo…
Inflammation of the liver
Fatty infiltration
acquired, reversible condition of metabolism, resulting in an…
Fatty infiltration CLINICAL
Asymptomatic... Minimal hepatomegaly... Minimal elevated LFTs
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