Study sets matching "nucleic acid synthesis"

Study sets
Classes
Users

Study sets matching "nucleic acid synthesis"

15 terms
Nucleic Acid and Protein Synthesis
Characteristics of DNA (SA - 3)
Base Pairing in DNA
Steps in DNA Replication (SA - key wor…
Characteristics of RNA (SA - 3)
-Made up of nucleotides (deoxyribose, phosphate, nitrogen bas…
A-T, C-G
1.) DNA unwinds... 2.) Helicase is used to separate the strands…
-Single strand... -Made up of ribose, phosphate... -Nitrogen bases…
Characteristics of DNA (SA - 3)
-Made up of nucleotides (deoxyribose, phosphate, nitrogen bas…
Base Pairing in DNA
A-T, C-G
24 terms
Nucleic Acid and Protein Synthesis
DNA
gene
binary fission
budding
double helix, is an organism's genetic material
code for a certain trait, part of DNA; discrete unit of hered…
(for all prokaryotes)... 1. DNA copies itself (attach to cell me…
1. "bud" of a new yeast cell... 2. nucleus stretches with bud as…
DNA
double helix, is an organism's genetic material
gene
code for a certain trait, part of DNA; discrete unit of hered…
Nucleic Acid and Protein Synthesis
nucleic acids
deoxyribonucleic acid
ribonucleic acid
genetic code
Large, complex organic molecules composed of C, O, H, N, P.
DNA stands for _______________.
RNA stands for _______________.
DNA carries the _______ ____.
nucleic acids
Large, complex organic molecules composed of C, O, H, N, P.
deoxyribonucleic acid
DNA stands for _______________.
35 terms
Nucleic Acid Synthesis
What are the three purine bases?
Name the corresponding nucleosides to…
Name the corresponding nucleotides to…
What is the form of the sugar in nucle…
Adenine, guanine, and xanthine
Adenosine, guanosine, inosine
adenylate, guanylate, IMP
Ribose
What are the three purine bases?
Adenine, guanine, and xanthine
Name the corresponding nucleosides to…
Adenosine, guanosine, inosine
39 terms
Nucleic Acid Synthesis Inhibitors
Objectives slide
Target of Nucleic Acid Synthesis Inhib…
What is folic acid?
Introduction
DNA
Humans need folic acid in our DIET... Important in the formatio…
Objectives slide
Target of Nucleic Acid Synthesis Inhib…
DNA
30 terms
Nucleic Acid Synthesis inhibtors
what are the 4 classes of nucleic acid…
what are the 2 inhibitors of folate sy…
what are the sulfa antimicrobials comm…
what is the prodrug that developed the…
1. inhibitors of folate synthesis... 2. fluoroquinolones... 3. Misc…
Sulfa antimicrobials and Trimethoprim
sulfonamides... (sulfanilamide)
protonsil
what are the 4 classes of nucleic acid…
1. inhibitors of folate synthesis... 2. fluoroquinolones... 3. Misc…
what are the 2 inhibitors of folate sy…
Sulfa antimicrobials and Trimethoprim
Nucleic Acid and Protein Synthesis
Transcription
Transcribed into RNA
Translation
Contains adenine-uracil pairs
Process by which the genetic code of DNA is copied into a str…
An expressed gene is one that does what?
Process of decoding MRNA into a polypeptide chain is know as…
Example that doesn't describe the structure of DNA
Transcription
Process by which the genetic code of DNA is copied into a str…
Transcribed into RNA
An expressed gene is one that does what?
5 terms
inhibition of nucleic acid synthesis
what do Quinolones and Fluoroquinolone…
antiviral drugs
what do Nucleotide or nucleoside analo…
what does Rifampin do?
Act against prokaryotic DNA gyrase that coils and uncoiling r…
Acyclovir, Nucleotide analogs, Ribiviran
-Interfere with function of nucleic acids... -Distort shapes of…
-Inhibitors of RNA polymerase during transcription... -binds to…
what do Quinolones and Fluoroquinolone…
Act against prokaryotic DNA gyrase that coils and uncoiling r…
antiviral drugs
Acyclovir, Nucleotide analogs, Ribiviran
Automated Nucleic Acid Synthesis
1.
2.
3.
4.
Detritylation with trichloroacetic acid
Activation of Phosporamidite with tetrazole
Addition of Activated phosphoramidite to growing chain
Capping: acetylation of 5'OH groups unreaced
1.
Detritylation with trichloroacetic acid
2.
Activation of Phosporamidite with tetrazole
61 terms
Nucleic acids/ protein synthesis
Nucleic acids
DNA
Nucleotide
Nitrogenous bases
- DNA ... - RNA
- double stranded helix... - never leaves the nucleus... - Watson,…
- building blocks of nucleic acids ... . Phosphate group... . Sugar…
Adenine... Thymine... Cytosine... Guanine
Nucleic acids
- DNA ... - RNA
DNA
- double stranded helix... - never leaves the nucleus... - Watson,…
Nucleic acid synthesis inhibitors
Name 5 Nucleic Acid Synthesis inhibitors
MOA of quinolones. Example of a drug
MOA of Nitroimidazoles. Example
MOA of Nitrofuran. Example
Quinolones... Nitroimidazoles... Nitrofurans... Sulfonamides... Dihydrofo…
Inhibitors DNA gyrase (unwinds DNA) and Topoisomerase IV (sep…
Metronidazole interacts with the anaerobic bacterial oxidored…
Nitrofurantoin is reduced by Nitrofuran reductase to form a t…
Name 5 Nucleic Acid Synthesis inhibitors
Quinolones... Nitroimidazoles... Nitrofurans... Sulfonamides... Dihydrofo…
MOA of quinolones. Example of a drug
Inhibitors DNA gyrase (unwinds DNA) and Topoisomerase IV (sep…
10 terms
Nucleic Acid Synthesis Inhibitors
Fluoroquinolones
Antifolates
Sulfonamides
Trimethoprim
Inhibit the action of Topoisomerase II in G- bacteria ... Topois…
Sulfonamides, Folate reductase inhibitors (trimethoprim)
Acts by inhibiting dihydropteroate synthetase... Absorbed and e…
Inhibitor of bacterial dihydrofolate reductase ... It s used in…
Fluoroquinolones
Inhibit the action of Topoisomerase II in G- bacteria ... Topois…
Antifolates
Sulfonamides, Folate reductase inhibitors (trimethoprim)
7 terms
Nucleic Acid Synthesis Inhibitors
Nucleic Acid Synthesis Inhibitors
Trimethoprim/Sulfamethoxazole Mechanis…
Trimethoprim/SulfamethoxazoleToxicities
Trimethoprim/Sulfamethoxazole Antibiot…
Trimethoprim/Sulfamethoxazole... Quinolones (-floxacin)
Inhibit Dihydrofolate Reductase, inhibiting the production of…
Rash --> Steven Johnson Syndrome... Interstitial Nephritis
MRSA, MSSA
Nucleic Acid Synthesis Inhibitors
Trimethoprim/Sulfamethoxazole... Quinolones (-floxacin)
Trimethoprim/Sulfamethoxazole Mechanis…
Inhibit Dihydrofolate Reductase, inhibiting the production of…
35 terms
Nucleic Acid & Protein Synthesis
Nucleotide Parts... (DNA)
DNA(Name)
# of Strands... (DNA)
Nitrogen Bases... (DNA)
5 carbon Sugar ... A phosphate group... Nitrogenous base
Deoxribonucleic Acid
(2)double helix
Adenine... Guanine... Cytosine... Thymine
Nucleotide Parts... (DNA)
5 carbon Sugar ... A phosphate group... Nitrogenous base
DNA(Name)
Deoxribonucleic Acid
7 terms
Nucleic Acid Synthesis Inhibitors
Fluoroquinolones
Rifamycin
Nalidixic Acid
Ciprofloxacin
Inhibit enzymes that maintain the supercoiling of closed circ…
Block prokaryotic RNA polymerase from inhibiting transcription
A quinolone used for treatment of UTI E.coli. Klebsiella, Ent…
A Fluroquinolone useful for treatment of many systemic infect…
Fluoroquinolones
Inhibit enzymes that maintain the supercoiling of closed circ…
Rifamycin
Block prokaryotic RNA polymerase from inhibiting transcription
23 terms
Nucleic acid synthesis inhibitors
Fluoroquinolone
Fluoroquinolone
Fluoroquinolone
Nitroimidazoles
Synthetic agents that inhibit DNA gyrase
Antibacterial
Ciprofloxacin
anaerobic conditions reduce the molecule which damages DNA an…
Fluoroquinolone
Synthetic agents that inhibit DNA gyrase
Fluoroquinolone
Antibacterial
Nucleic Acid Synthesis Inhibitors
Topoisomerase Inhibitors
Quinolones/Fluoroquinolones (FQs) MOA
FQs Spectrum
FQ 1st Generation EXAMPLE
Quinolones... Fluoroquinolones (FQs)
MOA - inhibit DNA replication by interfering with the action…
Broad G- coverage... Newer, "respiratory" FQs with improved G+…
Nalidixic acid - not used now
Topoisomerase Inhibitors
Quinolones... Fluoroquinolones (FQs)
Quinolones/Fluoroquinolones (FQs) MOA
MOA - inhibit DNA replication by interfering with the action…
28 terms
Nucleic Acid Synthesis Inhibitors
Naldixic Acid
Norfloxacin
Ofloxacin
Topoisomerase I
1st generation quinolone... Urinary infxn (mostly G-, minor effe…
2nd generation quinolone (similar to Cipro)... - Treat UTIs... - Ac…
2nd generation quinolone
Cuts ONE strand of DNA, opens up negative supercoil in bacter…
Naldixic Acid
1st generation quinolone... Urinary infxn (mostly G-, minor effe…
Norfloxacin
2nd generation quinolone (similar to Cipro)... - Treat UTIs... - Ac…
Nucleic Acid Synthesis Inhibitors
Fluoroquinolones
fluoroquinolone pharma
cipro
cipro use
ciprofloxacin (older)... levofloxacin, moxifloxacin (advanced or…
well absorbed in small intestine. but like tetracyclines: bin…
greatest ability against aerobic gram- bacilli.
UTI, osteomyelitis, chronic prostatitis/epididymitis, infecti…
Fluoroquinolones
ciprofloxacin (older)... levofloxacin, moxifloxacin (advanced or…
fluoroquinolone pharma
well absorbed in small intestine. but like tetracyclines: bin…
34 terms
Nucleic Acid Synthesis Inhibitors
Agents
Cellular targets
DNA gyrase (Topoisomerase II) function
Topoisomerase IV function
Rifamycin... Fidaxomycin... Fluoroquinolone... Metronidazole
DNA gyrase (Topoisomerase II)... Topoisomerase IV
Forms (-) supercoil by cutting, passing through, and reanneal…
Unknots by cutting and reannealing
Agents
Rifamycin... Fidaxomycin... Fluoroquinolone... Metronidazole
Cellular targets
DNA gyrase (Topoisomerase II)... Topoisomerase IV
111 terms
Nucleic Acid & Protein Synthesis
DNA
Substance of Inheritance
Hereditary Information
Biochemical, Anatomical, Physiological…
In 1953, James Watson and Francis Crick... introduced an elegant…
DNA, the _____, is the most celebrated molecule of our time.
Encoded in DNA and reproduced in all cells of the body.
This DNA program directs the development of four different tr…
DNA
In 1953, James Watson and Francis Crick... introduced an elegant…
Substance of Inheritance
DNA, the _____, is the most celebrated molecule of our time.
Nucleic Acid Synthesis Inhibitors
fluoroquinolones
fluoroquinolone moa
ciprofloxacin use
fluoroquinolone pharma
ciprofloxacin, levofloxacin, moxifloxacin
inhibits DNA gyrase and type IV topoisomerase
aerobic, gram-. UTI (E. coli), Osteomyelitis (P. aeruginosa),…
oral, IV, topical. absorbed in SI. like tetracyclines: bind d…
fluoroquinolones
ciprofloxacin, levofloxacin, moxifloxacin
fluoroquinolone moa
inhibits DNA gyrase and type IV topoisomerase
11 terms
Nucleic acid synthesis inhibitors
Topoisomerase inhibitors
FQ's
Second generation FQ
3rd generation FQ
Quinolones/Fluoroquinolones (FQs)... They inhibit DNA replicati…
Bactericidal and CONCENTRATION DEPENDENT killing ... Has broad…
Ciprofloxacin - UTI, GI and DOC for anthrax!
Levofloxacin - UTI, GI, URI and skin
Topoisomerase inhibitors
Quinolones/Fluoroquinolones (FQs)... They inhibit DNA replicati…
FQ's
Bactericidal and CONCENTRATION DEPENDENT killing ... Has broad…
22 terms
Nucleic Acid Synthesis Inhibitors
Nucleic Acid Synthesis Inhibitors
Fluoroquinolones Mechanism
Topoisomerase II
Topoisomerase IV
Target enzymes required for nucleic acid synthesis... Quinolone…
ENTER HOST CELLS (active against intracellular pathogens),…
DNA Gyrase... Relieves tension in ds DNA, relaxes supercoils
Separates & unlinks DNA for the next DNA replication
Nucleic Acid Synthesis Inhibitors
Target enzymes required for nucleic acid synthesis... Quinolone…
Fluoroquinolones Mechanism
ENTER HOST CELLS (active against intracellular pathogens),…
Inhibitors of nucleic acid synthesis
Rifamycin
Anti-tuberculosis
Ciprofloxacin and norfloxacin
Quinolones,fluoroquinolones,DNA Gyrase
Inhibits RNA synthesis:
Medication rifamycin
Examples of quinolones and fluoroquinolones:
__and__inhibits__.
Rifamycin
Inhibits RNA synthesis:
Anti-tuberculosis
Medication rifamycin
59 terms
Nucleic acid and protein synthesis
Types of nucleic acid
DNA
RNA
Nucleic acid is a
DNA ... RNA
Deoxyribonucleic acid
Ribonucleic acid
Organic molecule that contain all of the essential elements (…
Types of nucleic acid
DNA ... RNA
DNA
Deoxyribonucleic acid
6 terms
inhibitors of nucleic acid synthesis
inhibitors of nucleic acid synthesis
quinolones (nalidixic acid) and fluoro…
rifampin
metronidazole
competitive inhibition of essential nucleic acid precursor or…
inhibit bacterial DNA gyrase (the enzyme that controls DNA co…
inhibits transcription by binding to RNA polymerase and inhib…
causes breakage of microbial DNA (bacterial and parasitic DNA)
inhibitors of nucleic acid synthesis
competitive inhibition of essential nucleic acid precursor or…
quinolones (nalidixic acid) and fluoro…
inhibit bacterial DNA gyrase (the enzyme that controls DNA co…
Nucleic Acid and Protein Synthesis
DNA
Nucleotides
3 parts of a nucleotide
4 N bases of DNA
Deoxyribonucleic acid; Made of nucleotides
Building blocks of DNA
5 Carbon Sugar... Phosphate Group... Nitrogen Base
Adenine... Thymine... Guanine... Cytosine
DNA
Deoxyribonucleic acid; Made of nucleotides
Nucleotides
Building blocks of DNA
54 terms
Inhibitors of nucleic acid synthesis
Can humans synthesize folate?
Can bacteria synthesize folate?
Where do antibiotics compete with...
Folate is utilized for DNA synthesis b…
No... - Must be provided in the diet
Yes... - From precursors like p-aminobenzoic acid (PABA)
PABA for active site on enzyme (dihydropteroate synthase)
Humans & Bacteria
Can humans synthesize folate?
No... - Must be provided in the diet
Can bacteria synthesize folate?
Yes... - From precursors like p-aminobenzoic acid (PABA)
6 terms
Inhibitors of nucleic acid synthesis
Nalidixic acid- bacteriocidal
Nalidixic acid- mechanism of action
Ciproflaxacin- bacteriacidal
Ciproflaxacin-mechanism of action
Nalidixic acid is a quinolone antibacterial agent,it has mark…
Evidence exists for Nalidixic acid that its active metabolite…
Ciprofloxacin is a broad-spectrum antiinfective agent of the…
The mechanism of action of ciprofloxacin results from inhibit…
Nalidixic acid- bacteriocidal
Nalidixic acid is a quinolone antibacterial agent,it has mark…
Nalidixic acid- mechanism of action
Evidence exists for Nalidixic acid that its active metabolite…
Nucleic acid synthesis inhibitors
what are the abx classes of nucleic ac…
what is the MOA for nucleic acid synth…
fluoroquinolones inhibit what two enzy…
Cipro... infection
fluoroquinolones... metronidazole
prevent DNA replication by inhibiting key enzymes involved in…
DNA gyrase... type IV topoisomerase
UTI's... osteomyelitis... chronic prostatitis/epididymitis... infectio…
what are the abx classes of nucleic ac…
fluoroquinolones... metronidazole
what is the MOA for nucleic acid synth…
prevent DNA replication by inhibiting key enzymes involved in…
101 terms
Nucleic Acid Synthesis Inhibitors
quinolones, metronidazole, rifampin
inhibit enzymes required for DNA repli…
dna gyrase
topoisomerase 4
nucleic acid synthesis inhibitors
quinolones mechanism of action
where do quinolones bind to in gram negative organisms
where do quinolones bind to in gram positive organisms
quinolones, metronidazole, rifampin
nucleic acid synthesis inhibitors
inhibit enzymes required for DNA repli…
quinolones mechanism of action
53 terms
inhibitors of nucleic acid synthesis
Prontosil rubrum (red dye) was effecti…
Bacteria must synthesize its own _____…
Folic acid is composed of
How sulfonamides interferes with the s…
streptococcal infection... (prodrug couldn't be activated)
folate
Pteridine ring... p-aminobenzoic acid (PABA), and ... Glutamate
Sulfonamides structurally resembles PABA (p-amino benzoic acid)
Prontosil rubrum (red dye) was effecti…
streptococcal infection... (prodrug couldn't be activated)
Bacteria must synthesize its own _____…
folate
Inhibitors of Nucleic Acid Synthesis
Sulfamethoxazole
Sulfadiazine
Sulfasalazine
Sulfacetamide
Sulfonamides... MOA: stops dihydropteroate synthase (PABA). com…
Sulfonamides... MOA: stops dihydropteroate synthase (PABA). com…
Sulfonamides... MOA: stops dihydropteroate synthase (PABA). com…
Sulfonamides... MOA: stops dihydropteroate synthase (PABA). com…
Sulfamethoxazole
Sulfonamides... MOA: stops dihydropteroate synthase (PABA). com…
Sulfadiazine
Sulfonamides... MOA: stops dihydropteroate synthase (PABA). com…
nucleic acid synthesis inhibitors
what is the mechanism of nucleic acid…
will NASI harm the host?
which is the indication for NASI?
are NASI broad or narrow spectrum?
binds to DNA dependent RNA polymerase so it blocks initiation…
no, because of the differences between prokaryotic and eukary…
TB, leprosy and MAC pneumonia
broad
what is the mechanism of nucleic acid…
binds to DNA dependent RNA polymerase so it blocks initiation…
will NASI harm the host?
no, because of the differences between prokaryotic and eukary…
11 terms
+nucleic acid and protein synthesis
chromosomes are made of
a gene Is a
dna determines the
the chromosomes of an eye cell compare…
dna which wraps around protein to condense
segment of dna with the instructions to build one protein
proteins made by an organism which then determines its traits
identical
chromosomes are made of
dna which wraps around protein to condense
a gene Is a
segment of dna with the instructions to build one protein
16 terms
Nucleic Acid Synthesis Inhibitors
List the 5 main categories of Nucleic…
List the 4 generations of Fluoroquinol…
What is the mechanism of action for qu…
What is the mechanism of action for Qu…
Fluoroquinolones ... Polymyxin B ... Metronidazole... Nitrofurantoin... D…
1) Nalidixic acid - not used much anymore ... 2) CON ... Ciprofloxa…
inhibition of topoisomerase 4 enzyme
inhibition of DNA gyrase enzyme
List the 5 main categories of Nucleic…
Fluoroquinolones ... Polymyxin B ... Metronidazole... Nitrofurantoin... D…
List the 4 generations of Fluoroquinol…
1) Nalidixic acid - not used much anymore ... 2) CON ... Ciprofloxa…
81 terms
Inhibitors of Nucleic Acid SYnthesis
SMX and TMP individually are bacterios…
together they are
DOC for Pneumocyctis jirovecii**
Cotrimoxazile affects both
static
cidal and synergistic
cotrimioxazole
GP and GN
SMX and TMP individually are bacterios…
static
together they are
cidal and synergistic
inhibitors of nucleic acid synthesis
Rifampin
Fidoxamin
Fluoroquinolones
Sulfonamides
RNA polymerase inhibitor... Induces metabolism of other drugs... Us…
RNA polymerase inhibitor... narrow spectrum... C. diff
Ciprofloxacin, levofloxacin, moxifloxacin... Inhibit DNA replica…
Indirect inhibition of DNA synthesis... Competitive inhibitor in…
Rifampin
RNA polymerase inhibitor... Induces metabolism of other drugs... Us…
Fidoxamin
RNA polymerase inhibitor... narrow spectrum... C. diff
22 terms
Nucleic Acid Synthesis Inhibitors
What are the 2 main subgroups that fal…
Fluoroquinolones are derived from ____…
Fluoroquinolones inhibit the DNA gyras…
Fluouroquinolones are bacteri_____.
Fluoroquinolones... Rifamycins
Urinary naldixic acid
topoisomerase destroys the human cell's DNA.
bactericidal
What are the 2 main subgroups that fal…
Fluoroquinolones... Rifamycins
Fluoroquinolones are derived from ____…
Urinary naldixic acid
25 terms
Nucleic Acid and Protein Synthesis
DNA is
RNA is
nucleic acid is made of the organic mo…
nucleotides are - bonded
deoxyribonucleic acid
ribonucleic acid
C H O N P
covalently
DNA is
deoxyribonucleic acid
RNA is
ribonucleic acid
Nucleic Acids and Protein Synthesis
Friedrich Miescher
Frederick Griffith
Transformation
Oswald Avery
1869 Germany was studying chemistry of cells (white blood cel…
1920's trying to find a cure for pneumonia, a bacteria called…
incorporation of a piece of foreign DNA into the genome of a…
did a follow up to Griffith's experiment and concluded it was…
Friedrich Miescher
1869 Germany was studying chemistry of cells (white blood cel…
Frederick Griffith
1920's trying to find a cure for pneumonia, a bacteria called…
39 terms
Nucleic Acid Synthesis and Metabolism
DNA
RNA
Nucleotides
Nucelosides
Missing an O on 2' C
O on all C
Nitrogenous base, sugar, and phosphate group
Nitrogenous base attached to a 5 C sugar (sugar has no phosph…
DNA
Missing an O on 2' C
RNA
O on all C
35 terms
Gochin: Nucleic Acid Synthesis
What are the three purine bases?
Name the corresponding nucleosides to…
Name the corresponding nucleotides to…
What is the form of the sugar in nucle…
Adenine, guanine, and xanthine
Adenosine, guanosine, inosine
adenylate, guanylate, IMP
Ribose
What are the three purine bases?
Adenine, guanine, and xanthine
Name the corresponding nucleosides to…
Adenosine, guanosine, inosine
43 terms
Nucleic Acid Synthesis Inhibitors
What are fluoroquinolones' MOA?
Are fluoroquinolones bactericidal or b…
Fluoroquinolone's ability to kill bact…
Which 2nd generation fluoroquinolone i…
inhibit DNA replication
bactericidal
concentration dependent
ciprofloxacin
What are fluoroquinolones' MOA?
inhibit DNA replication
Are fluoroquinolones bactericidal or b…
bactericidal
Disruption of Nucleic Acid Synthesis
Fluoroquinolones (aka quinolones)
Two enzymes used in fluoroquinolones t…
True or False: Gyrase is a type of top…
Gyrase removes supercoils by _________…
Gyrase inhibitor; Have two enzymes to counter nucleic acid sy…
Gyrase and Topoisomerase
True
holding onto
Fluoroquinolones (aka quinolones)
Gyrase inhibitor; Have two enzymes to counter nucleic acid sy…
Two enzymes used in fluoroquinolones t…
Gyrase and Topoisomerase
12 terms
Nucleic Acids and Protein Synthesis
Friedrich Miescher
bacteriophage
Lytic Cycle
Lysis
-first isolated DNA... -Swiss Physician... -discovered is pus of di…
virus that infects a bacteria
1. phage attaches to the cell... 2. virus infects the bacterium…
the bursting of a cell
Friedrich Miescher
-first isolated DNA... -Swiss Physician... -discovered is pus of di…
bacteriophage
virus that infects a bacteria
45 terms
Nucleic Acids and Protein Synthesis
DNA
RNA
Nucleotides
Bases
deoxyribonucleic acid
ribonucleic acid
DNA and RNA are unbranched polymers of repeating monomer unit…
the nitrogen-containing bases in nucleic acids are derivative…
DNA
deoxyribonucleic acid
RNA
ribonucleic acid
32 terms
Nucleic Acids and Protein Synthesis
DNA
DNA shape
each nucleotide consists of
purines
Deoxyribonucleic Acid
double helix
one sugar- deoxyribose, one phosphere- PO4^3, one nitrogen ba…
composed of two rings
DNA
Deoxyribonucleic Acid
DNA shape
double helix
42 terms
Inhibitors of Nucleic acid synthesis
Inhibitors of Nucleic acid synthesis f…
Human beings source of folate comes fr…
Bacteria Synthesize their own folate f…
bacteria synthesize _______ that is re…
1. Inhibitors of folic acid synthesis... 2. Direct inhibitors of…
dietary... Cannot synthesize folate
para-aminobenzoic acid (PABA)
tetrahydrofolate
Inhibitors of Nucleic acid synthesis f…
1. Inhibitors of folic acid synthesis... 2. Direct inhibitors of…
Human beings source of folate comes fr…
dietary... Cannot synthesize folate
1 of 10